s*****y 发帖数: 4595 | 1 4.3
Breakfast
Great Value - Texas Toast - Garlic Bread, 1 slice 150
Horizon Organic - Fat-Free Milk , 1 cup 90
Lunch
Generic - Homemade Chicken and Fried Rice With Eggs/Veggies, 1 Cup 426
Dinner
Generic - Homemade Chicken and Fried Rice With Eggs/Veggies, 1 Cup 426
Generic - Seaweed Soup (Home Made0, 1 cups 215
Snacks
Snickers - Icecream Bar, 1.8 bar 324
Cranberries - Dried, sweetened, 0.1 cup 37
Nestle - Crunch Chocolate Bar, 0.5 bar (43.9g) (1.55 oz) 110
Exercises
Walking, 3.5 mph, uphill 350... 阅读全帖 |
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c**********e 发帖数: 413 | 2 贴一下今天吃的东西吧~用 myfitnesspal算的,格式有点乱将就看吧
总之就是吃了1202卡,运动285
半夜猛吃的零食也都算进来了。平时大约最多也就吃这样了。运动呢一周1600-2100卡
就大家关心的cheese, 今天这里有4片*60=240卡(app算70我懒的改)
但不是如果cheese不吃能少摄入240卡,显然我不吃cheese也要吃别的 。。。。
感觉今天确实吃的有点多,看看明天体重会不会掉吧
最后倒立,其实……挺累的……
Breakfast Calories Carbs Fat Protein Sodium Sugar
Kraft - Slice of Cheese, 2 slice 140 4 8 8 440 2
Quick Added Calories, 40 calories 40 0 0 0 0 0
Generic - Single Raw Peanut, 30 peanut 180 8 28 6 180 ... 阅读全帖 |
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c**********e 发帖数: 413 | 3 贴一下今天吃的东西吧~用 myfitnesspal算的,格式有点乱将就看吧
总之就是吃了1202卡,运动285
半夜猛吃的零食也都算进来了。平时大约最多也就吃这样了。运动呢一周1600-2100卡
就大家关心的cheese, 今天这里有4片*60=240卡(app算70我懒的改)
但不是如果cheese不吃能少摄入240卡,显然我不吃cheese也要吃别的 。。。。
感觉今天确实吃的有点多,看看明天体重会不会掉吧
最后倒立,其实……挺累的……
Breakfast Calories Carbs Fat Protein Sodium Sugar
Kraft - Slice of Cheese, 2 slice 140 4 8 8 440 2
Quick Added Calories, 40 calories 40 0 0 0 0 0
Generic - Single Raw Peanut, 30 peanut 180 8 28 6 180 ... 阅读全帖 |
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h****n 发帖数: 17 | 5 there are generic versions of Clindamycin gel and Tretinoin, you can either
ask your doctor the the pharmacist to replace the brand drug with the
generic.
sometimes though, generic drugs might not be as good as the brand, due to
formulation difference. |
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d*****d 发帖数: 10658 | 6 哦,是接受美学啊。Generic Architecture是建筑师Koolhas的概念,他写了一本厚书
generic city,主要讲现在全球化,城市建筑都可以造得一样,如此也带来同质化的城
市景观。比如罗山机的别墅群移植到上海来也完全可以。我觉得美国城市同质化严重,
downtown一撮高楼,然后就是郊区house群,costco,walmart摆设都一样。幸好中国现
在还没有很generic city,各地还很不同。 |
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l*****l 发帖数: 5909 | 7 来自主题: LeisureTime版 - 走在尘世间 个人认为无关句式手法的创意意象一般没有抄袭一说。
就算有,也要在原始对象有一定的独特性的前提下。
而这种独特性的程度判定,也要看是否超越generic的认知。
比如陀螺旋转所以(或者是 为了)不倒下,就是generic的认知。
比如陀螺旋转产生的幻觉感,晕眩感,不稳定感,感觉周围世界在旋转,
这都是人类自己旋转就能产生的自然感觉,所以是generic的。
而shot这首诗的第二段表达的在旋转中陀螺膨胀而成为世界本身的概念,相对就算是有
一定独特性的创意。 |
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d********t 发帖数: 837 | 8 化学锁男明天就能在实验室合成blue pill ,$0.99一大罐,你丫敢吃吗?generic有通
过审批的就有通不过审批的,如果监管没用的话你下次可以申请把没通过审批的药都拿
来用。另外FDA管的是你能不能label上写上和非generic一样的indication,不管你能不
能生产。一般药厂不会脑残去批量生产没被批的药是因为没人敢去用,而不是FDA不准
你生产。你丫知道generic 审批看什么吗?给你个脑残片吃进去血液浓度比品牌药高十
倍,在体内多呆一个月你敢吃吗?CMC数据你不审批你知道下批生产出来的药片跟你用
来做对照试验的药一样吗?杂质多十倍,有效成分减半你负责吗?
准: |
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m***u 发帖数: 1 | 9 来自主题: PsychoAnalysis版 - 抑郁症的药 你别买brand name,要买generic.
Zoloft 的成分是sertraline,你就去drug store买sertraline,完全一样。
Zoloft的专利权大约一年前过期了,所以就大大便宜了俺们消费者。以前我吃zoloft
(50mg pay day)一个月要付40美刀,现在只付5美刀。你没有prescription
insurance,吃generic大概10美刀/月。
你去跟医生将,不要开brand name,开generic好了。 |
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c*******n 发帖数: 1648 | 11 我就不懂了,大药厂自己不能都搞个GENERIC的DIVISION?成本应该比其他GENERIC的药
厂低,本来就是自己的药,熟门熟路,不就一下子把GENERIC的公司给干掉了? |
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c********1 发帖数: 517 | 12 这就是华尔街的人跟我们华理人在思路上的层次。不过我也是听工作的人说的哈。
人家是这样想的:我同样雇用100个人,有个5亿美元的facility。现在做generic,收
入只有原来的1/3。那就是说,我的股票就要掉价。
现在我这么干:我把那批针对完蛋的产品的R&D砍掉。假定说上面100个人,砍了。去做
一个新的药,重新去雇用100个新人新知识。结果是同样的固定投资,同样的人员开销
,我的revenue还是跟原来一样。我的股票还是那么值钱。
这就是他们说的什么投资的边际效用之类的东西。那你说原来的东西就这么不要了?是
这样的,通常他们会把原来的整个卖了。据说在自由市场里面,假定你接着generic,
每年给你带来的是多少的钱,跟你现在去把它卖了,收益差不多。就类似说那滩东西被
折旧了。
然后那买家为啥买哪?比如说他刚干完一件同样的事情。手上有比钱。但是本行业回报
很差。投资制药有想法,但是怕风险。那就先上一个generic。然后再说。倒时候原来
那家公司还会帮着把你的resume往那个地方递。当然工资从9万跳到6万。类似的意思。
总之一句话,科学家,工程师,都是靠出卖自己体力,又没有自己 |
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s******n 发帖数: 876 | 15 I read it somewhere but I can't be sure I remember it clearly.
Apparently, even before Generics, at java byte code level,
a class is allowed to have two methods of same signature,
if they have different return types.
class A // pseudo byte code
f(List)->String
f(List)->Integer
The byte code reference to a method actually includes the
return type, therefore the two methods can be distinguished.
// pseudo byte code invoking two methods
(A.f(List)->String) ();
(A.f(List)->Integer) ();
Of ... 阅读全帖 |
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Z**0 发帖数: 1119 | 16 你grub出错,出来的是什么错误?
title Ubuntu 8.04.2, kernel 2.6.24-23-generic
root (hd0,1)
kernel /boot/vmlinuz-2.6.24-23-generic root=UUID=d0621a00-e4f9-4911-
b404-7899c2c7b350 ro quiet splash
initrd /boot/initrd.img-2.6.24-23-generic
quiet
从上面的这个看,你的grub.conf没有问题。按理用uuid,系统不应该出现问题。
可能你需要安装一次grub。
http://ubuntuforums.org/showthread.php?t=224351 |
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h***r 发帖数: 726 | 17
由于有两套/boot/grub/menu.lst, (hd0,0) 有如下typo
title Ubuntu 8.10, kernel 2.6.27-14-generic
uuid
kernel /boot/vmlinuz-2.6.27-14-generic
root=UUID= ro quiet splash
initrd /boot/initrd.img-2.6.27-14-generic
把old改成new就可以了. (测试通过)
另外run grub, root (hd0,0) setup (hd0) 或者
root (hd0,3) setup (hd0) 可以指定使用哪个分区的menu.lst |
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S*A 发帖数: 7142 | 18
Stack-based VM is hard to do normal function optimization like CSE.
You can in theory undo the stack and convert them back to SSA
form. A lot of modern compiler transformation is depend on SSA.
Convert stack to SSA takes memory and CPU time. In modern C
compilers, most of the time is spend on IR transformation.
The C front end is very fast.
That is why Java better use JIT, it only work on the hot path,
and most of the scalor is already on the stack. It can not afford
to full optimization of the... 阅读全帖 |
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x*********s 发帖数: 5554 | 19 话说为了接光驱,把本来接/dev/sda装windows的硬盘拔了,接上光驱,安装centos,
拔掉光驱,接上装有windows的硬盘。
然后直接起动,进入一个只有centos信息的grub。如果改变启动磁盘顺序,还能进入一
个有以前windows+ubuntu信息的grub。
我想将两个grub合并,但总是失败,下面分别贴两个grub.cfg的信息和磁盘信息,看看
有没有大侠帮帮忙,看看怎么能把windows+ubuntu的grub信息写到centos的grub里面去:
###########################
sudo cat /boot/grub/grub.cfg
menuentry 'Ubuntu, with Linux 2.6.32-33-generic' --class ubuntu --class gnu-
linux --class gnu --class os {
recordfail
insmod ext2
set root='(hd1,1)'
search --no-floppy --... 阅读全帖 |
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b*****e 发帖数: 17 | 20 When I write rules in makefile
Chap12.o : chap12.cpp chap12.h generic.h
g++ -c -I $(include_path) chap12.cpp
generic.h is included in chap12.h and chap12.h is included in chap12.cpp
Do I need to put generic.h in prerequisite?
Thanks. |
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G***l 发帖数: 355 | 21 这个说的是Java,因为JVM不支持Generics,runtime还是会做cast,所以Java里用
Generics不比不用快。C#的Generics不需要runtime cast。
types
no |
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g*****g 发帖数: 34805 | 22 C#出来的时候有个屁linq,而且Java从来没有linq也没见啥功能
实现不了。Java 5 04年出来的,之前没有Generics,
C# 02年出来的,没得抄所以也没有Generics。到06年C# 2.0的时候
就有Generics了。还好意思说不是抄的。 |
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g*****g 发帖数: 34805 | 23 你妈要有多不要脸,才能成天意淫这些,历史都能改写。你要不是无知,就是脸皮够厚。
C#控件程序员,对java不满意俺们压力很大。
Generics are a facility of generic programming that was added to the Java
programming language in September 2004 as part of J2SE 5.0.
Generics were added to version 2.0 of the C# language ... Since the release
of C# 2.0 in November 2005 |
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f***c 发帖数: 338 | 24 写了一段代码,用g++编译顺利通过。
想到前几天曾讨论过编译器对int main(),void main()的处理不同问题,就顺手试了cc
和gcc。这一试不打紧,居然都不能通过。
OS: Debian GNU/Linux 6.0.3 (squeeze)
然后就看看个编译器的version,居然是一样的。但是对同样的代码的编译处理区别怎
么这么大呢?
彻底懵了,请达人解惑,谢谢。
g++ -v
Using built-in specs.
Target: x86_64-linux-gnu
Configured with: ../src/configure -v --with-pkgversion='Debian 4.4.5-8' --
with-bugurl=file:///usr/share/doc/gcc-4.4/README.Bugs --enable-languages=c,c
++,fortran,objc,obj-c++ --prefix=/usr --program-suffix=-4.4 --enable-shared
--enable-multiarch --enab... 阅读全帖 |
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k**********g 发帖数: 989 | 25
system
I know nothing about functional programming but I know at least a little
about C++ metaprogramming. Also I am very familiar with generic programming.
I have the feeling that,
(1) Unless the end-users of your language are compiler-writers or language
researchers (that is, users of your language use it to write their own
compilers or design their own languages),
(2) All other users outside this niche can have their practical programming
needs fulfilled with just generics, run-time code gen... 阅读全帖 |
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k**********g 发帖数: 989 | 26
system
I know nothing about functional programming but I know at least a little
about C++ metaprogramming. Also I am very familiar with generic programming.
I have the feeling that,
(1) Unless the end-users of your language are compiler-writers or language
researchers (that is, users of your language use it to write their own
compilers or design their own languages),
(2) All other users outside this niche can have their practical programming
needs fulfilled with just generics, run-time code gen... 阅读全帖 |
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k**********g 发帖数: 989 | 27
For this type of question, there is no generic answer.
The only answer you can give, is Your Own Answer, from your own experience.
You can't fake it.
"as much as you know" means that you need to write your own autobiography.
Just give an example of why there can't be generic answer:
Suppose that for 95% of existing websites, content type X is static. So, it
does not need to be updated in real-time. Thus, many caching strategies can
be used for this content type.
For the remaining 5% of websites... 阅读全帖 |
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w***g 发帖数: 5958 | 28 要说C#加入generic是被java 5逼的我觉得没问题。要说抄我倒是看不出来。java C#和
C++的generic各不相同,很难说哪两个更接近。要说抄,最多也就是java和C#都抄了C+
+。Generic有哪几中方法也不是啥高深的知识,design space大家应该早就都想清楚了,
C#和java做了不同的选择而已。 |
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c*****t 发帖数: 1879 | 29 最近无聊,稍微研究了下两个语言,彻底被雷了。
第一是 R 。可以说是世界上最 fucked up 的语言之一(COBOL 是另外一个)。
你看一下这篇文章就明白了:
https://xianblog.wordpress.com/2010/09/13/simply-start-over-and-build-
something-better/
如果你非要写 R 代码。建议你把所有的 variable 都弄个 prefix 。免得你
不小心碰到这种麻烦事。
第二就是 Go 。整个一傻逼语言。
1) 如果该语言有 pointer,但是其速度比 Java 还慢点,谁 TMD 有病才用它。
再不用说,Go 里面需要知道很多很多 low level 的东西,但是搞了半天比 Java
还慢?!!
2) Stupid copies 。好吧,你有 pointer 不用,非得 pass by value (i.e.
struct copy),真是脑袋抽筋了。copy 大部分情况下比 reference 慢。
reference 是可以放在 register 里的,而 struct 一旦比 register... 阅读全帖 |
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c*****t 发帖数: 1879 | 30 最近无聊,稍微研究了下两个语言,彻底被惊呆了。
第一是 R 。可以说是世界上最 fucked up 的语言之一(COBOL 是另外一个)。
你看一下这篇文章就明白了:
https://xianblog.wordpress.com/2010/09/13/simply-start-over-and-build-
something-
better/
第二就是 Go 。整个一傻逼语言。
1) 如果该语言有 pointer,但是其速度比 Java 还慢点,谁 TMD 有毛病才用它。
再不用说,Go 里面需要知道很多很多 low level 的东西,但是搞了半天比 Java
还慢?!!
2) Stupid copies 。好吧,你有 pointer 不用,非得 pass by value (i.e.
struct copy),真是脑袋抽筋了。copy 大部分情况下比 reference 慢。
reference 是可以放在 register 里的,而 struct 一旦比 register 大,
就会占内存。然后 Go idiots 说 cache 很 precious,那你还搞那么多 copy... 阅读全帖 |
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f*******t 发帖数: 7549 | 31 不能简单评价是缺点还是优点。Go的理念是语法必须简单,让码工写起来恶心,但不容
易写出无法维护的代码。不支持generic隐含的意义是强迫码工断绝让一段代码支持多
种类型的念头。写lib是一回事,而对app来说这显然是有利的。一段business logic如
果只处理int,出错的概率显然比既支持int又支持string小。
某种程度上generic可以通过interface实现,但实践中它主要用来做DI,test时注入
mock组件。
真正的generic语义,比如自带的sort package,很不顺手,确实不如fancy的新语言“
简洁”。我不认为这完全是坏事。swift写个运算符就能当匿名函数用,简化到极致,
但我总觉得哪里不对劲 |
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发帖数: 1 | 32 Which language has the brightest future in replacement of C between D, Go
and Rust? And Why?
In spite of my status and obvious bias as co-creator of D, I'll do my best
to answer candidly; I follow Go and Rust, and I also definitely know where D
's dirty laundry is. I'd encourage people with similar positions in the Rust
and Go communities to share their honest opinion as well. So here goes.
First off, C++ needs to be somewhere in the question. Whether it's to be
replaced alongside C, or be one o... 阅读全帖 |
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K******S 发帖数: 10109 | 33 【 以下文字转载自 Pharmaceutical 讨论区 】
发信人: bleu (好奇杀死猫), 信区: Pharmaceutical
标 题: Merck to Cut Up to 13,000 Jobs
发信站: BBS 未名空间站 (Fri Jul 29 10:17:30 2011, 美东)
By PETER LOFTUS
Merck & Co. said Friday that it would widen its cost-cutting measures by
eliminating up to 13,000 jobs—on top of the 17,000 layoffs in prior actions
—as the drug maker faces generic competition and other pressures.
The Whitehouse Station, N.J., company disclosed the job cuts as it reported
a near-tripling of second-quarter earning... 阅读全帖 |
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l**********1 发帖数: 5204 | 34 How to sort a generic List
After reading this post from Steven Smith I thought I should write something about it.
Sorting a generic List is pretty straightforward if you know how to do it. With C# 2.0, anonymous
methods come at hand, as well as the little known Comparison delegate (check out this post for more
information about this class as well as other useful classes new to C# 2.0).
Ok, let's suppose we have a product class (let me save some space by using C# 3.0 syntax).
-----
Publi... 阅读全帖 |
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s**********e 发帖数: 2888 | 35 你这个是在胡说,FDA 3年前就对ciprofloxacin发布了safety alert
http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInforma
Information for Healthcare Professionals: Fluoroquinolone Antimicrobial
Drugs [ciprofloxacin (marketed as Cipro and generic ciprofloxacin),
ciprofloxacin extended-release (marketed as Cipro XR and Proquin XR),
gemifloxacin (marketed as Factive), levofloxacin (marketed as Levaquin),
moxifloxacin (marketed as Avelox), norfloxacin (marketed as Noroxin), and
ofloxacin (marketed as Floxin)]
F... 阅读全帖 |
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I***a 发帖数: 704 | 36 In Design Compiler, 我用write_sdf命令得到的.sdf文件back-annotate到综合后的
verilog netlist总是有这个问题:
Instance '/FFT8inputs/\Regs_4/Q_reg[20] ' does not have a generic named 'tpd
_clk_q_posedge'.
tpd_clk_q_posedge, tpd_clk_qbar_posedge, tsetup_d_clk_posedge_posedge,
tsetup_d_clk_negedge_posedge, thold_d_clk_posedge_posedge, thold_d_clk_
negedge_posedge,
这6个generic参数说是对应的DFF cell里没有:
entity DFF_E is
generic(
TimingChecksOn: Boolean := True;
InstancePath: STRING := "*";
Xon: Boolean := False;
... 阅读全帖 |
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s*****t 发帖数: 247 | 37 听说小硕很难到Scientist,最多Chemist.现申请了一个Sciensit 职位,也拿到了onsite
.我的背景化学+药学(国内,硕士),在国内做过数个ANDA,一个NDA(做到临床),来美国后
又拿了个非化学硕士(主要做分析).此职位主要focus on generic R&D.过来人给说说可
能性怎样? 还是说generic的Scientist比新药研发的Scientist的门槛底很多?
电面的时候问了一些技术方面的细节,我感觉答得不是太好,但好在以前在国内的项目做
得比较踏实,面世我的director还是比较满意.所以拿到了Onsite.但director同时问我
如果降到chemist III 我还接不接受.我说没问题,但同时我也说我现在最需要的是熟悉
他们的环境,相信我很快就能达到Scientist的要求,Director也说他相信这一点.
不知版上有没有在generic里混的大侠?给说说entry level scientist和Chemist III的
薪水如何?如果能拿到scientist,是不是对以后的职业发展会好点?我已经找了大半年了
,对这个机会还是充满 |
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t*d 发帖数: 1290 | 38 Thanks a lot.
One more question: How do you understand the following sentence in your
linked article?
When asked whether pharmacists can assume that a reference-listed drug
product with a protected indication is interchangeable with a generic
equivalent, Rickman said that the products are deemed bioequivalent "even
though a generic may not be approved for all indications for which the
innovator drug is approved."
Does it mean the pharmacists have liberty to give patients a generic
equivalent of |
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j******w 发帖数: 97 | 40 Biosimilar 刚出来的时候还挺感兴趣的。但现在看来3-5年都成不了气候,假设可以成气候的话。。。对了。现在很多人在讲 Generic User Fee. 不知道会对Generic Industry 有什么影响。估计中国的Generic 药厂就更不愿意搞美国市场了。
hearing |
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B****a 发帖数: 1526 | 41 http://finance.yahoo.com/news/Teva-to-buy-Cephalon-for-68-rb-55
On Monday May 2, 2011, 8:48 am EDT
By Lewis Krauskopf
NEW YORK (Reuters) - Teva Pharmaceutical Industries Ltd struck a deal to
acquire U.S. specialty drugmaker Cephalon Inc (NasdaqGS:CEPH - News) for
nearly $7 billion, topping an unsolicited bid by Canada's Valeant
Pharmaceuticals International Inc and boosting its brand-name drug business.
Teva's (Tel Aviv:TEVA.TA - News; NasdaqGS:TEVA - News) $81.50-a-share deal
is a nearly 12 per... 阅读全帖 |
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v**a 发帖数: 2062 | 42 低潮高潮都是正常现象,低潮如果持续太长,那这个industry就逐渐萎缩甚至死掉,如
果低潮只是暂时几年,现在不投入R&D的十多年后也会衰败掉。往往science上的一个小
突破就能度过低潮了。
搞generic大公司比不过专做generic的公司,generic赚的那点小钱也远填不了大公司
现在的漏洞。搞science还是需要规模效应的,学校里牛lab出东西也比小lab快而多。
小公司也许成本效率方面有某些优势,但是最终是敌不过规模效应的。 |
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b**u 发帖数: 2761 | 43 By PETER LOFTUS
Merck & Co. said Friday that it would widen its cost-cutting measures by
eliminating up to 13,000 jobs—on top of the 17,000 layoffs in prior actions
—as the drug maker faces generic competition and other pressures.
The Whitehouse Station, N.J., company disclosed the job cuts as it reported
a near-tripling of second-quarter earnings on a tax benefit and other items.
Revenue rose 7% on sales growth for diabetes drugs Januvia and Janumet, as
well as anti-inflammatory drug Remicade.
... 阅读全帖 |
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L******r 发帖数: 522 | 44 确实有这种可能,而且现在还不是可能,是有无数的例子。所以去年Generic吵得最热
闹的事情就是GDUFA,就是将来generic也交钱,FDA也需要10个月内完成审批。业界已
经在去年跟FDA达成了一致,就等着FDA拿出最后的草案,然后交到congress去走程序,
最快估计今年10月就可以下来。到时候对generic会产生非常重大的影响,因为将不仅
仅是费用增加问题,还有个要害就是将来FDA估计会发更多的warning letter,cGMP的
要求会越来越高,我个人希望是把那些弄虚作假的老印狠狠再收拾下。 |
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j******w 发帖数: 97 | 45 Generic/biosimilar user fees are coming...
The U.S. Food and Drug Administration has completed its recommendations for
three user fee programs that will help speed safe and effective drugs and
lower-cost generic drug and biosimilar biological products to patients, FDA
Commissioner Margaret A. Hamburg, M.D. said today. The recommendations were
transmitted to Congress today by Health and Human Services Secretary
Kathleen Sebelius.
The programs include the fifth authorization of the Prescription Dr... 阅读全帖 |
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h*******o 发帖数: 4884 | 46 个人的粗浅理解
对于biologics来说,在2009年前,由于没有类似于ANDA的505j 申请, 不管brand name的
biologics的patent有没有失效, generic 公司都必须提交类似于全新BLA的申请, 这意
味着要进行完整的preclinical & clinical study. 所以你即使成功的void一个
biologics patent1) 也不会有180天的market exclusivity; 2)你的产品还是要完整的
BLA. 这个对于generic公司来说是很难实现的.
至于biologics专利有没有被challenge过,我个人印象是有,我记的是UPenn的一个stem
cell还是gene therapy的patent就被判无效过.
2009年以后FDA出台了类似于ANDA的biosimilarity的条例,相当于大幅度的简化了
biologics generic的申请要求.
当时09年的时候市场普遍对Amgen之类的公司持负面观望态度. 至于这个新的法案能多
大程度上鼓励biologics,还要过一些年才能知道. |
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L******r 发帖数: 522 | 47 我不在Momenta工作。
Momenta现在被Sandoz/Novartis买下来了,他们主要是做一些比较复杂的分子的
generic,不能算传统的generic,也不是真正意义的biosimilar (我个人起码不这么认
为)。最成功(也是目前唯一一个成功,不过确实赚了好多钱,所以他们才这么招人)
的就是号称第一个blockbuster的generic Enoxaparin。他们的核心技术大概是对一些
高分子,多糖.....进行成分分析(只能这么简单说说了),你去恶补下biosimilar的
基本知识,读读他们关于Enoxaparin的专利和这段历史(包括他们跟FDA 的那些
Citizen Petition讨论),估计聊天的时候会比较有用。
Good Luck. |
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t*****n 发帖数: 64 | 48 前面根大家提到有一个offer,因为工作的领域(大分子)比较喜欢,公司发展也不错
,文化据说不错,决定接受offer,尽管工资比较低,title也降,也没有商讨的余地。
结果这周接2连3又来了几个比较实际的offer,工资至少比前面的大分子工作高$15k,
工作我肯定能胜任,因为是我所在的领域,但是觉得自己学习的机会会少。几家公司都
还不错。其中值得考虑的是个大的generic company,还给我升了一个title。我很是
feel being respected and valued。就是我对generic有一点偏见,总觉得他们的
research低人一等,没有innovation。我个人还是很value original research。一开
始没有料到他们会出这么高的价,这一出价高,我还真有点心动。
面对我喜欢的工作,钱少,路远,起点低,和generic的工作,钱多,路近些,起点高
,怎么选?周一的定下来了。 |
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