C********1
发帖数: 5281 | 1 http://www.khou.com/story/news/2015/08/14/breaking-large-explos
DrillChem is an oil industry supply company that creates sealants, shale
inhibitors and lubricants, according to their website.
There is another oilfield service company that also uses the same name
however, this company is located in Corpus Christi, Texas.
这个炼油厂是产密封剂，润滑剂页岩密封剂的，好像不生产汽油，所以应该是利用生产
汽油柴油的炼油厂剩下的残渣再炼油，对石油的利用，和汽油的生产关系不大.大家说
说？ |
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a*****1
发帖数: 3134 | 2 all TNF alpha inhibitors have black box warning and all are blockbuster
drugs. |
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b*********f
发帖数: 2125 | 3 search LOXO101 Trk inhibitor 的第一个药！ 顺便推荐另一个潜力股GLYC！！ |
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B***E
发帖数: 2001 | 4 glyc指标上最近看跌
俩星期之前涨的确实好看,没赶上
还有啥推荐的没
: search LOXO101 Trk inhibitor 的第一个药！ 顺便推荐另一个潜力股GLYC！！
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f*******1
发帖数: 1308 | 5 INCY还是相当猛的，有批了的药 JAK1/JAK2 inhibitors (Jakafi), 还有Iclusig (BCR
-ABL),另外在小分子抑制剂（JAK, PI3K, LSD1,FGFR, PIM,BRD...)和Immunotherapy(
IDO1, PD-1, ARG, OX40, GITR...)还有一堆很有意思的pipeline,针对各种肿
瘤的。 |
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发帖数: 1 | 6 目前celg 并购Juno的消息还悬在半空中。从肿瘤界的角度看，这不是个坏的主意，如
果说肿瘤界这几年的热点是immune check point inhibitor，让BMS和Merck嫌了个足，
那么今后几年的热点就会是CART 了，大的制药公司都会卷入的，利益驱使。药物的疗
效是硬道理，有疗效就有市场。JUNO 在CART界的地位和技术注定了它不会沉寂太久，
即便不被Celg并购，也会被其他的公司惦记上的。即便是不被并购，它的前景也会很棒
的。 |
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f*******1
发帖数: 1308 | 7 U.S. FDA Approves Portola Pharmaceuticals’ Andexxa®, First and Only
Antidote for the Reversal of Factor Xa Inhibitors
GlobeNewswire•May 3, 2018 |
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发帖数: 1 | 8 MD Anderson Cancer Center，号称世界上最牛的癌症研究和治疗机构
这里的医生这么讲：他们实际发现Vitrakvi (larotrectinib) 对15-20%的癌症病人（
无论什么癌）完全有效。他们想在每位癌症病人身上使用这种神药。他们从没见过如此
好的疗效。
“There are a lot of critics of precision medicine right but I’ll tell you:
if you ever put a patient on a TRK inhibitor like larotrectinib [for a
solid-tumor cancer], you’ll want to test everybody because the responses
are just incredible,” said David Hong, MD, of the University of Texas MD
Anderson Cancer Center in Houston. “Complete responses in 15%–20%... 阅读全帖 |
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d*******u
发帖数: 5337 | 9 Hi reviewers,
I wish you all have a happy new year.
Please check the following manuscripts to Biomedicine and pharmacotherapy.
If you are interested in reviewing these manuscripts, send your background
and Ms #. Feel free to pass this information to your friends and collogues.
Best regards,
xxxx
Executive editor
Biomedicine and Pharmacotherapy
1. Antiproliferative activity of Corylus avellana L. extracts against
human cancer cell lines
2. Poloxamer Surface modified Trimethyl Chitosan Nano... 阅读全帖 |
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g****d
发帖数: 238 | 10 OAP 旗下 Journal of Drug Resistant Pathogen Research，无分非SCI哦，稿件情况
如下：
Title: In Vitro Activity of Iclaprim Against Methicillin-Resistant
Staphylococcus aureus Nonsusceptible to Daptomycin, Linezolid or Vancomycin
Abstract:
Iclaprim is a novel bacterial dihydrofolate reductase inhibitor in Phase 3
clinical development for the treatment of acute bacterial skin and skin
structure infections and hospital acquired bacterial pneumonia caused by
Gram-positve bacteria. Daptomycin, linezolid and vancomyci... 阅读全帖 |
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c******e
发帖数: 350 | 11 RFE le.
移民局要求递交材料以证明以前研究项目的重要性. 这些材料必须由曾经引用过我的文
章的主要作者提供, 指出被引用部分的意义.
One professor wrote:
"The major significance of this manuscript was that XXX gene upregulates YYY
, member of the inhibitor of apoptosis family, expression. Therefore, the
imbalance of increased anti-apoptosis and decreased pro-apoptosis seen in
HCC is a critical mechanism leading to the uncontrolled growth of tumour
cells."
My attorney read it and said "These statements are helpful only if they
describe how they used your wor... 阅读全帖 |
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L******r
发帖数: 141 | 12 All the materials were taken from Administrative Decisions (Aliens with Extraordinary Ability/ Outstanding Professors and Researchers). 所以这些话是权威!!!
I downloaded All the AAO decisions for the past three years. I read one by one for a total number of more than 200 decisions. I took good paragraphs from recommendation letters which IOs thought have met criterion of contribution. Because the works were from PDF files, I had to reformat them into word file.
It took me many hours to do the work and I... 阅读全帖 |
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b*******g
发帖数: 1040 | 13 昨天晚上8点左右，收到手机短信，没有说结果，只是说decision了,让自己上网查，赶
紧上网，紧张得看到信脑袋都没反应，还是老公先说了approve了，我开始嚎叫，发现
两个娃也里屋外屋的嚎叫，才发现自己太兴奋了。
自己背景真的很弱，所以才有中彩票的感觉！
先说time line:
Eb1b pp
RD 27th December 2011
AD 4th January 2012
除去新年放假，就一周时间。网上状态一直是acceptance，直接进入decision. 真是应
了版上牛人的pp总结，如果1周左右出结果，多半是好消息。
背景再说一下:
国内医学本科+ 小硕士
文章：英文一作3，通讯1(向国内导师要的，影响因子<1)，coauthor 1。会议摘要 2。
所有的IF< 4
中文 6。
引用：一片英文文章引用来自14个国家，其他都都是中文引用，不区分他引自引共68次。
审稿：32次，来自5个国家。
就这些，无奖无报道。
死马当活马医，为什么我起这么个标题，大过年的，就是想鼓励背景较弱的同学。也许
大家觉得我文章有，审稿有，引用也有，不算弱。请注意，我是cancer re... 阅读全帖 |
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a**l
发帖数: 219 | 14 关键词： Quantitative structure–activity relationship, PTP1B Inhibitors;
journal还不错，if 4点几。
如果感兴趣，站内信。请将联系方式告诉我，我再推荐给主编，主编给谁我就不知道了
... |
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b*********r
发帖数: 7139 | 15 ☆─────────────────────────────────────☆
brighttiger (hehehehe) 于 (Fri Sep 28 09:11:34 2012, 美东) 提到:
每逢佳节倍思亲，移民版版务提前祝大家中秋节快乐！！
☆─────────────────────────────────────☆
wachwu (wachwu) 于 (Fri Sep 28 09:12:15 2012, 美东) 提到:
chi,
☆─────────────────────────────────────☆
lover00 (caicai) 于 (Fri Sep 28 09:12:35 2012, 美东) 提到:
Yeah!!!第一个！
☆─────────────────────────────────────☆
hsutau (xixi) 于 (Fri Sep 28 09:12:44 2012, 美东) 提到:
哇咔咔 吃吃！！
☆─────────────────────────────────────☆
canhelp... 阅读全帖 |
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S***R
发帖数: 309 | 16 please send your name, email address and simple description to my mail box.
thanks. |
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z***i
发帖数: 383 | 21 Brown Recluse Spider Bite Mediated Hemolysis: Clinical Features, a Possible
Role for Complement Inhibitor Therapy, and a Potential Biomarker of Venom
Exposure
有相关研究的人给我发个简历,我看着合适推荐一下,不过推荐不保证editor一定给.
l*******[email protected] |
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F**9
发帖数: 56 | 22 Any one interested, please email me.
review opportunity. Journal: Corrosion Science
ABSTRACT:
The possibility of using newly synthesize N,N?-bis(4-hydroxybenzaldehyde)-1
,2-cyclohexan diimine (4-HBC) Schiff base as a corrosion inhibitor of API 5L
steel in 1 M HCl solution was investigated by polarization curves, AC
impedance measurements, current transient and SEM and AFM techniques. It
was shown that the inhibition effectiveness increases with an increase in
the concentration of 4-HBC and a de... 阅读全帖 |
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z********4
发帖数: 533 | 23 准备eb1a中，但是有好几个引用下不来，请大家帮帮忙，list在下面，请发到我的邮箱
z***********[email protected] 先谢谢各位了！
1.Antigenic diversity and seroprevalences of Torque teno viruses in children
and adults by ORF2-based immunoassays
J Gen Virol February 2013 vol. 94 no. Pt 2 409-417
2.Tunicamycin induces resistance to camptothecin and etoposide in human
hepatocellular carcinoma cells: role of cell-cycle arrest and GRP78
JL Hsu, PC Chiang, JH Guh - Naunyn-Schmiedeberg's archives of …, 2009 -
Springer
3.p53 antagonizes the unfolded prote... 阅读全帖 |
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z********4
发帖数: 533 | 24 准备eb1a中，但是有好几个引用下不来，请大家帮帮忙，list在下面，请发到我的邮箱
z***********[email protected] 先谢谢各位了.
1.Enhanced autophagic flux by endoplasmic reticulum stress in human
hepatocellular carcinoma cells contributes to the maintenance of cell
viability
Oncology Reports July 2013 Volume 30 Number 1
2.Proteomic dissection of viral pathogenesis
HC Liu, J Hicks, D Yoo - 2010 - Animal Genomics for Animal Health
International Symposium, Paris, October 2007: Proceedings
3.Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)
T... 阅读全帖 |
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V**F
发帖数: 164 | 25 I have referred one ID with the closest background to the manuscript. Sorry
to others.
****
For toxicology journal impact factor >4, one of the top journals in
toxicology.
Key words: Optical coherence tomography, MAPK/ERK kinase (MEK) inhibitors
Please send me your brief background and contact info if you think you will
be able to handle this manuscript.
I will refer you to the editor.
**** |
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f**********e
发帖数: 6 | 27 hi
Here is my cv, it would be appreciated if I can have the chance to review
the article.
Thanks
Hao
Harvard Medical School
Curriculum Vitae
Name: Hao Wang
Office Address: Department of Cancer Immunology and AIDS
Dana-Farber Cancer Institute
Harvard University
3 Blackfan Circle, CLSB 1010
Boston, MA 02215
Home Address: 103 Gordon street,
Boston, MA 02120
Work Phone: (617) 602-6786
W... 阅读全帖 |
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b*****f
发帖数: 851 | 28 I have a major concern of how to define my field. I am now writing to ask
for your suggestions.
Basically, my research work has focused on the following two areas,
1. Bioactive peptides in venomous cone snails (conopeptides or conotoxins),
particularly the isolation and characterization of novel conopeptide ligands
which can discriminate between closely related receptors and ion channels
and be developed for the treatment of neuropathic and inflammatory pain.
Conopeptides or conotoxins are neu... 阅读全帖 |
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i****g
发帖数: 55 | 30 Bioorganic & Medicinal Chemistry的manuscript，关于inhibitors of Mt-FabG4。
请把一个能证明审稿能力的CV发给我。 会转给第一个符合条件的。
同时为自己马上要三个月的EB1B求个祝福，学校不给PP，只能干等。周围的朋友不少两
个月多一点就批了，自己的快三个月了。听说版上祝福很灵，来求个祝福。 |
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t**********r
发帖数: 35 | 31 【 以下文字转载自 Chemistry 讨论区 】
发信人: troublewater (trouble), 信区: Chemistry
标 题: medicinal chemistry review opportunity
发信站: BBS 未名空间站 (Tue Jun 24 11:07:54 2014, 美东)
Sorry can't input Chinese...
There's a review opportunity if someone is interested. The journal is Future
Medicinal Chemistry. The paper is about synthesis, biochemical evaluation,
and molecular modeling of several non-toxic, and selective
butyrylcholinesterase inhibitors for Alzheimer’s disease.
If you have related background and are wil... 阅读全帖 |
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i****g
发帖数: 55 | 32 转让一篇paper review，from BMC （IF： 2-3）。
Key words: inhibitors of DNA gyrase B.
会转给第一个符合条件的，希望没收到的不要有意见。 |
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c****e
发帖数: 172 | 33 已给lz站内信！
做的enzymology，study of enzymes in bacteria for screening inhibitors.
谢谢！ |
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l****t
发帖数: 916 | 34 请问review还有效吗，我是做medicinal chemistry的，主要是inhibitors的合成和SAR
研究 |
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x***2
发帖数: 3345 | 35 关键词 Enzyme inhibitors
请悄悄话联系方式。 |
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x***2
发帖数: 3345 | 36 1.Bioorganic & Medicinal Chemistry
2.Organic & Biomolecular Chemistry
请发姓名，单位，email，和简单介绍给我。 |
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p*******i
发帖数: 141 | 38 杂志：Apoptosis
标题：Synergistic effect of apoptosis and necroptosis inhibitors in
cisplatin-induced nephrotoxicity
有意者请短信息 简单用英文介绍一下背景，这样可以转发给主编。最后还须看主编的
意向。
PS: 套用的jill422网友的模版，多谢！ |
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v*******n
发帖数: 8995 | 39 好像非常合适我的背景，请考虑一下我， 谢谢
ying wang
[email protected]
/* */
背景是molecular biology，cancer(ovarian cancer, tumor metastasis)/stem cell
biology
文章有molecular cell 和cancer research
1. Wang Y, Arribas-Layton M, Chen Y, Lykke-Andersen J, and Sen GL.DDX6
Orchestrates Mammalian Progenitor Functionthrough the mRNA Degradation and
Translation Pathways. Mol Cell. doi:10.1016/j.molcel.2015.08.014
2. Mistry DS, Chen Y, Wang Y, Sen GL. Transcriptional profiling of SNAI2
regulated genes in primary human kerat... 阅读全帖 |
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a*********0
发帖数: 268 | 40 转让life science 审稿一篇。Y-27632, a Rho-associated protein kinase
inhibitor, inhibits voltage-dependent K+ channels in rabbit coronary
arterial smooth muscle cells. 需要background 介绍和email，姓名以便推荐。 |
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T**7
发帖数: 264 | 41 请发给我：
你的
（1）简短的PUBLICATION LIST 不超过5篇文章
（2）你的名字
（3）学位
（4）EMAIL地址
Entitled "Asymptomatic bacteriuria increases the risk of edematous attacks
in hereditary angioedema due to C1-inhibitor deficiency"
Article Type: Original Article
Background: Although urinary tract infections are considered among the most
common infectious disorders in humans, these usually follow an uncomplicated
course. Various infections may have a role in inducing HAE attacks. Further
, danazol treatment has been associated ... 阅读全帖 |
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i********n
发帖数: 171 | 42 8.Xiaoxianggou attenuates atherosclerotic plaque formation in endogenous
high Ang II ApoE-/- mice via the inhibition of miR-203 on the expression of
Ets-2 in endothelial cells
9.Loss of Raf kinase inhibitor protein is associated with malignant
progression in hepatic fibrosis
10.Bio-fabricated silver nanoparticles preferentially targets gram positive
depending on cell surface charge
11.Rosiglitazone elevates sensitization of drug-resistant oral epidermoid
carcinoma cells to vincristine by G2/M-ph... 阅读全帖 |
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i********n
发帖数: 171 | 43 Please send your CV to [email protected]/* */ with selected MS#. 请务必认真审稿并及
时提交意见，谢谢
1. Iptakalim induces mitochondria-dependent apoptosis in hypoxic rat
pulmonary arterial smooth muscle cells
2. Fyn-related kinase expression predicts favorable prognosis in patients
with cervical cancer and suppresses malignant progression by regulating
migration and invasion
3. The Protective effect of Citrus limon essential oil on Hepatotoxicity
and nephrotoxicity induced by aspirin in rats
4. ... 阅读全帖 |
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i********n
发帖数: 171 | 44 请发邮件到[email protected]/* */
1. Synthesis and characterization of chitosan–polyvinylpyrrolidone–
bovin serum albumin coated magnetic iron oxide nanoparticles as potential
carrier for delivery of tamoxifen
2. n-vitro and In-silico anticancer potentials of taxoids isolated from
Taxus wallichiana Zucc
3. Homology modeling and virtual screening for inhibitors of lipid kinase
PI(4)K from Plasmodium
4. Evidence for the involvement of nitric oxide in cholestasis-induced
itch associated... 阅读全帖 |
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d*******u
发帖数: 5337 | 45 1. Novel pH-sensitive nanosponges as effective carrier for oral delivery
of naproxen
2. Biphenyl tetrazole-thiazolidinediones as novel bacterial peptide
deformylase inhibitors: Synthesis, biological evaluations and molecular
docking study
3. PEGylated long circulating liposomes deliver homoharringtonine to
suppress multiple myeloma cancer stem cells
4. Antiproliferative and apoptotic effects of black turtle bean extracts
on human breast cancer cell line through extrinsic and intrinsi... 阅读全帖 |
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i********n
发帖数: 171 | 46 请发邮件到[email protected]/* */
1. Novel pH-sensitive nanosponges as effective carrier for oral delivery
of naproxen
2. Biphenyl tetrazole-thiazolidinediones as novel bacterial peptide
deformylase inhibitors: Synthesis, biological evaluations and molecular
docking study
3. PEGylated long circulating liposomes deliver homoharringtonine to
suppress multiple myeloma cancer stem cells
4. Antiproliferative and apoptotic effects of black turtle bean extracts
on human breast cancer cell l... 阅读全帖 |
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i********n
发帖数: 171 | 47 Send your CV and MS # to [email protected]/* */, and please reply here with MS #.
Thanks
1. In-silico screening for DNA-dependent protein kinase (DNA-PK)
inhibitors: combined homology modeling, docking, molecular dynamic study
followed by biological investigation
2. Fast and long acting neoflavonoids dalbergin isolated from Dalbergia
sissoo heartwood is osteoprotective in ovariectomized model of osteoporosis
3. Synthesis of stable nanosilver particles (AgNPs) by the proteins of
se... 阅读全帖 |
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i********n
发帖数: 171 | 48 请发简历及你想审稿的文章编号，可以多选。
同时提醒一下审稿人，请不要为了申绿卡而忽视了审稿质量，请大家珍惜下一次审稿机
会。
Please email to: [email protected]/* */
1. MiR-486-5p functions as a tumor suppressor and directly targets VEGFA
in human osteosarcoma
2. Novel quercetin derivative TEF induces ER stress and mitochondria-
mediated apoptosis in human colon cancer HCT-116 cells
3. Antioxidant, anti-microbial, anti-inflammatory and wound healing
effects of Artemisia campestris aqueous extract on rat
4. Identification of novel HDAC2 inh... 阅读全帖 |
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i********n
发帖数: 171 | 49 请发简历及你想审稿的文章编号， 尽量会照顾大家，一般给我邮件都有机会，尽量多
选几篇你相关的领域。
同时提醒一下审稿人，请重视审稿质量，希望大家都有下一次审稿机会。
Please email to: [email protected]/* */
1. Identification of novel VP35 inhibitors: virtual screening driven new
scaffolds
2. Long non-coding RNA SNHG5, which is downregulated by estradiol,
suppresses breast cancer cell proliferation
3. anti-inflammatory, analgesic and antipyretic activities of grapevine
leaf extract (Vitis vinifera) in mice and identification of its active
constituents by LC-MS/MS ... 阅读全帖 |
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i********n
发帖数: 171 | 50 有审稿意愿的请发送你的CV到[email protected]/* */并告知你希望审稿的文章编号
请有时间愿意多审几篇的也可以，只要你能保证质量，之前有些审稿人有些敷衍，希望
大家能认真对待。谢谢合作。
1. Comparative assessment of cytotoxic effect of Cuban and Brazilian
propolis in human laryngeal epidermoid carcinoma cells
2. Role of PI3K/AKT/mTOR signaling pathway in ostearthritis by regulating
articular chondrocytes autophagy in rats
3. CREB knockdown inhibits growth and induces apoptosis in human pre-B
acute lymphoblastic leukemia cells through inhibition of prosurvival sig... 阅读全帖 |
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