l*****e
发帖数: 110 | 1 Sorry I can not type Chinese in the lab.
mm,as I said, I know exactly what you are going through! Be positive! It
happened to me just a few month before you, but my husband and I handle it
quite well.
Abnormal pap smear could mean many things. It includes CIN I, II, III,
cancer-instu, or worse. If it is the early stage of cervical cancer (before
cancer metastasis), it is not a life-threatening disease and has more than
99% cure rate. We should feel really lucky for that! Timing for the this
dis |
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E*********n
发帖数: 144 | 2 我想你是hearsay吧，一会说骨转移后活了两年，一会说发现时全身扩散，然后活了十
几年。全身扩散还进行了手术？ 只要有remote metastasis, 手术就不再可能，一般是
系统化疗，局部放疗，加靶向。我可以负责得告诉你，癌症的愈后和病人的心情毫无关
系。癌症的愈后的决定因素是癌症的种类，分期，癌细胞的分化程度，是否转移，以及
手术切割的干净程度。所以早期发现，尽早手术是关健。 |
|
l****x
发帖数: 53 | 3 非SCI杂志Cancer Growth and Metastasis寻找guest editor，需要guest editor邀稿
并审邀到的稿子。感兴趣的同学请联系我。 |
|
p*******r
发帖数: 156 | 4 Postdoctoral positions available
A postdoctoral position is available in the Laboratory of Cellular and
Molecular Biology at the National Cancer Institute. A focus of current
studies is understanding the contribution of integrin adhesion complexes,
including focal adhesions and invadopodia, to the control of cancer cell
proliferation and survival. A class of proteins called the Arf GTPase-
activating proteins (Arf GAPs), which regulate the Ras-superfamily proteins
Arfs and integrin adhesions, ... 阅读全帖 |
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S******i
发帖数: 71 | 5 【 以下文字转载自 Biology 讨论区 】
发信人: Suozucai (Zuzu), 信区: Biology
标 题: 南方医科大学中西医结合医院院长罗荣城教授严重剽窃他人论文，发表到diagnostic pathology.
发信站: BBS 未名空间站 (Wed Oct 7 21:14:58 2015, 美东)
南方医科大学中西医结合医院院长罗荣城教授严重剽窃他人论文，发表到diagnostic
pathology.
见过造假的，没见过这么造假的。。。。。。
论文公司的科学家学习学习吧，一本万利
The microRNA-1246 promotes metastasis in non-small cell lung cancer by
targeting cytoplasmic polyadenylation element-binding protein 4 (Weihua
Huang, Huifen Li, and Rongcheng Luo, 2015, Diagnostic Pathology
Journal)
MicroRNA-550a acts as a pr... 阅读全帖 |
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b****n
发帖数: 75 | 6 【 以下文字转载自 Biology 讨论区 】
发信人: bioben (hehe), 信区: Biology
标 题: 吉林大学中日联谊医院青千招聘（癌症系统生物学）
发信站: BBS 未名空间站 (Sat Feb 3 12:27:02 2018, 美东)
Faculty and Qin Qian positions at the CSBC at JLU
http://csbc.org.cn/
We are looking for energetic and talented people to join our faculty (吉林大
学中日联谊医院肿瘤系统生物学中心, http://csbc.org.cn/). We are particularly interested in receiving applications from candidates with background in
(1) cancer systems biology;
(2) cancer metabolomics;
(3) studies of relationships between ch... 阅读全帖 |
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h*******3
发帖数: 38 | 7 I'd like to write a review regarding Tumor Microenvironment and metastasis.
I am working at a top national research institute in cancer field. My email is h******[email protected]
内容：
在申请EB1的同学。字数在5000-6000字，大约3个月内完成。
最后能发表的同学肯定可以得到邀请信，不需要出版费用。
杂志的编辑会在3月再和大家联系。 |
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m**n
发帖数: 750 | 8 I have written more than two reviews. I'd like to contribute in the
following part.If needed, I'd love to provide my CV for your evaluation.
Thank you for the opportunity. here is my email address: t*********[email protected].
miRNA and metastasis |
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l******g
发帖数: 83 | 9 hi, I'm interested in the following three topics. and my email is t**********[email protected]
Thanks.
Tumor Microenvironment and metastasis
Cancer stem cell and chemotherapy
Cancer epigenetics
内容：
在申请EB1的同学。字数
在5000-6000字，大约3个月内完成。
最后能发表的同学肯定可以得
到邀请信，不需要出版费用。
杂志的编辑会在3月再和大家
联系。 |
|
f******e
发帖数: 921 | 10 Hi, I am interested in these two topics: Cancer and Inflammation
Tumor Microenvironment and metastasis. I have several papers in cancer and
inflammation signaling pathway studies. I could provide my CV. My email is:
g****[email protected] |
|
R******E
发帖数: 159 | 11 Cancer and Inflammation
miRNA and metastasis
Thank you,
h****[email protected] |
|
z*****g
发帖数: 306 | 12 Hi 你好！
姓名Zhenwei Zhang
单位Northshore University HealthSystme, University of Chicago
邮箱z*****[email protected]
领域cancer biology, experimental cancer therapy, metastasis, virus.
Reviewed for Mol Cancer Ther, Mol Medicine, JECCR.
Thanks a lot! |
|
c********g
发帖数: 2075 | 13 给老板审过包括CNS在内的杂志一百多篇，自己受邀给5点多的杂志审过5篇，审稿经验
绝对丰富，有信心让我审稿的请联系email: b***[email protected] 或者站短。 多谢了啊啊
啊啊啊啊。
关键词：
cell signaling, especially TGF-beta and Wnt pathways;
Post-translational modifications;
Kinases, phosphatases, ubiquitin ligases and DUBs;
Proteasome functions and regulations;
Cell cycle control, oncogenes and tumor suppressors;
In vitro and in vivo tumor models;
Cancer metastasis.
neuroscience
neural regeneration |
|
t*****2
发帖数: 213 | 14 也替老公求review机会，同求，谢谢了。
背景：
cancer biology
cancer metastasis and drug resistance
human and cancer genetics
Cell Biology
molecular biology
BioChemistry
Genomic biology
blood cell malignancies |
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R*******d
发帖数: 13640 | 15 【 以下文字转载自 Biology 讨论区 】
发信人: liujiatian (liujiatian), 信区: Biology
标 题: 2015年影响因子新出炉
发信站: BBS 未名空间站 (Thu Jun 18 23:51:32 2015, 美东)
Rank full journal title Total Cites IF
1 ca-a cancer journal for clinicians 18,594 115.84
2 new england journal of medicine 268,652 55.873
4 lancet 185,361 45.217
6 nature biotechnology 45,986 41.514
7 nature 617,363 41.456
12 nature materials 64,622 36.503
13 jama-journal of the american medical assoc... 阅读全帖 |
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h*********9
发帖数: 35 | 16 UCA1 functions as a competing endogenous RNA to suppress epithelial ovarian
cancer metastasis
tumor biology 据掉审稿的时候可以推荐审稿人，有兴趣的把email和主页发给我。 |
|
发帖数: 1 | 17 因绿卡申请需要，急需攒review数量，恳请帮忙。
本人有过几篇独立审稿经验。如有请联系[email protected]
/* */。
不胜感激！
Post-transcriptional regulation
RNA biology (e.g. RNA silencing, RNA splicing)
small RNA (e.g. microRNA, siRNA, tRNA)
cancer biology
Cancer metastasis |
|
i********n
发帖数: 171 | 18 请发简历及你想审稿的文章编号，可以多选。
到[email protected]/* */
1. Combination of 2-deoxy D-glucose and metformin for synergistic
inhibition of non-small cell lung cancer: A reactive oxygen species and P-
p38 mediated mechanism
2. MYC gene regulating the occurrence and metastasis of prostate cancer
by STAT signaling pathways
3. Ursolic Acid Mediates Hepatic Protection through enhancing of anti-
aging biomarkers.
4. New insight on using aged garlic extract against toxic impacts of
titanium dioxide... 阅读全帖 |
|
i********n
发帖数: 171 | 19 请发简历及你想审稿的文章编号， 尽量会照顾大家，一般给我邮件都有机会，尽量多
选几篇你相关的领域。
同时提醒一下审稿人，请重视审稿质量，希望大家都有下一次审稿机会。
Please email to: [email protected]/* */
1. Identification of novel VP35 inhibitors: virtual screening driven new
scaffolds
2. Long non-coding RNA SNHG5, which is downregulated by estradiol,
suppresses breast cancer cell proliferation
3. anti-inflammatory, analgesic and antipyretic activities of grapevine
leaf extract (Vitis vinifera) in mice and identification of its active
constituents by LC-MS/MS ... 阅读全帖 |
|
i********n
发帖数: 171 | 20 请发简历以及相应的审稿文章编号到[email protected]/* */
1. Possible Contributions of Thyroid Hormone Replacement to Specific
Behaviors of Cancer
2. ATTENUATING EFFECT OF GYMNEMA SYLVESTRE ON STREPTOZOTOCIN-NICOTINAMIDE
INDUCED DIABETIC NEPHROPATHY IN RATS
3. Estrogen and Thyroid Cancer is a stem affair. A preliminary study
4. Therapeutic outcomes of autologous CIK cells as a maintenance therapy
in the treatment of lung cancer patients: A retrospective study
5. Role of gastrointestinal motili... 阅读全帖 |
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k********r
发帖数: 12 | 21 Breast Cancer: Basic and Clinical Research杂志招收4-6名guest editors。
主要任务：
在四个月内招收3到5篇关于Molecular Basis of Breast Cancer Progression and
Metastasis主题的投稿，发表在Breast Cancer: Basic and Clinical Research的
supplement。这些投稿会经过peer review选出可以发表的文章。最后四个月和所有的
editor和 journal staff 一起编辑发表。
出版费：
Authors in North America: USD$1386
Authors in other countries: GBP￡1040
每个guest editor手下如果有两篇或者以上投稿被接受的话，可以有选择一篇给予免出
版费的权利。
Benefits of the role：
The role will be a valuable addition to your CV and you will also become a... 阅读全帖 |
|
k********r
发帖数: 12 | 22 Breast Cancer: Basic and Clinical Research杂志招收4-6名guest editors。
主要任务：
在四个月内招收3到5篇关于Molecular Basis of Breast Cancer Progression and
Metastasis主题的投稿。这些投稿会经过peer review, 发表在Breast Cancer: Basic
and Clinical Research。最后，另外四个月所有的editor和 journal staff 一起编辑
发表。
出版费：
Authors in North America: USD$1386
Authors in other countries: GBP￡1040
福利：
每个guest editor手下如果有两篇或者以上投稿被接受的话，可以有选择一篇给予免出
版费的权利。
出版后，所有guest editor都会成为杂志deitor board的一员。个人信息会被陈列在网
站guest editorial一栏里。
自己或者同一单位的同事有在Breast Cancer: Basic and ... 阅读全帖 |
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p****2
发帖数: 8 | 23 求肿瘤／心血管／生物物理方面的审稿机会。非常感谢！
具体方向为：
Tumor metastasis
tumor microenvironment
oncogene
epigenetics
emzymology
signal transduction
cardiac myopathy (hypertension, atherosclerosis and myocardial infarction)
nanoparticle-based drug delivery
live cell imaging
receptor-ligand binding kinetics
CRISPR/Cas9
transgenic mouse models
如果有合适的审稿机会可否推荐？ 请私信我。
万分感谢！ |
|
p****2
发帖数: 8 | 24 求肿瘤／心血管／生物物理方面的审稿机会。非常感谢！
具体方向为：
Tumor metastasis
tumor microenvironment
oncogene
epigenetics
emzymology
signal transduction
cardiac myopathy (hypertension, atherosclerosis and myocardial infarction)
nanoparticle-based drug delivery
live cell imaging
receptor-ligand binding kinetics
CRISPR/Cas9
transgenic mouse models
如果有合适的审稿机会可否推荐？ 请私信我。
万分感谢！ |
|
c**i
发帖数: 6973 | 25 My comment:
(a) Vice President of Taiwan Vincent C. Siew was diagnosed with lung cancer,
stage IIIB. Apparently during operation, metastasis was observed in the
form of white dots on pleura His doctors said 5-year survival rate would be
90%. That is a joke! After all, it is just a step away from the terminal
stage of IV.
Lababede O, Meziane MA and Rice TW, TNM Staging of Lung Cancer; A Quick
Reference Chart. Chest (January 1999) vol. 115 no. 1 233-235.
Omar Lababede, MD, Moulay A. Meziane, MD, a |
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s*****c
发帖数: 753 | 26 蛋蛋癌 cure rate is very high. 70%-80%, I believe. Lance Armstrong has
that and Cancer already metastasis to his brain, but he is still cured and
win 6 championship. |
|
|
g***r
发帖数: 22 | 28 It is extremely important to have a diagnosis before jumping into surgery.
Some adrenal tumors are benign and do not need treatment, for example
functionally inactive adrenal adenomas. Some tumors, such as
pheochrsmocytomas, need medical treatment to control blood pressure before
surgery to prevent side effects of the operation. Malignant tumors and
metastasis need different appoaches in management.
Both adrenal CT and MRI are very helpful to confirm the diagnosis or point
to some differential d... 阅读全帖 |
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P*A
发帖数: 7996 | 29 除非安德森不是地球开的，地球上的科技目前对metastasis无解 |
|
y**w
发帖数: 516 | 30 来就事论事检讨一下哈。
HA有文献证明可以通过外敷渗入，不是渗析机理，而是有transporter.
文献：http://www.nature.com/jid/journal/v113/n5/abs/5600510a.html
再来严谨一下，
第二点“和HA有作用的一些酶的确在癌扩散期扮演了重要角色” 文献：
(1) Bharadwaj AG, et al. Inducible hyaluornan production reveals
differential effects of prostate tumor cell growth and tumor angiogenesis. J
Cell Biol. 2007;282:20561-20572
(2) Gao F, et al. Hyaluronan oligosaccharides are potential stimulators to
angiogenesis via RHAMM mediated signal pathway in wound healing. Clinical
and Investigative Med... 阅读全帖 |
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G***a
发帖数: 27294 | 31 ☆─────────────────────────────────────☆
Ivraie (vicia) 于 (Fri Mar 2 03:53:31 2012, 美东) 提到:
今晚参加韩国LG公司'ISA KNOX'系列新产品TE'RVINA在LA的发布会，据说TE'RVINA是首
批应用human placenta用作cosmetics的产品（以前只用animal placenta，比如羊胎素
）。
使用人体胎盘as the raw material for cosmetics是不合乎法律的，所以LG公司
extract only the superior skin regenerating substances from the effective
ingredients of the human placenta utilizing the patent technology and human
placentas of CHA Medical Center (一间人体胎盘研究很强的医学中心）。
简言之，LG公司用一种专利技术成功从人体胎盘中提炼对人类皮肤有re... 阅读全帖 |
|
|
f********i
发帖数: 8412 | 33 Not because of luck, but the cancer type, stage, especially metastasis. |
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c**********r
发帖数: 891 | 34 现在的西医跟中医一样也是唯象的。什么stem cell，什么metastasis，无非是花哨的
名词而已，连这些东西的精确定义都没有，换句话说连这些东西是否是真实存在的还是
人类想象的都搞不清，跟中医的气、筋脉什么的没有本质区别。五十步百步的关系。
已经比较清楚的知道了各个组成部分的功用，然后研究整体的性质，和根本对组成部分
的性质一无所知，玩弄玄学性的“整体”，根本是两回事。 |
|
l*****o
发帖数: 26631 | 35 Long-Term Health Risks and Benefits Associated with Spay / Neuter in Dogs
Laura J. Sanborn, M.S.
May 14, 2007
Precis
At some point, most of us with an interest in dogs will have to consider
whether or not to spay / neuter our pet. Tradition holds that the benefits
of doing so at an early age outweigh the risks. Often, tradition holds sway
in the decision-making process even after countervailing evidence has
accumulated.
Ms Sanborn has reviewed the veterinary medical literature in an exhaustive
a... 阅读全帖 |
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c****g
发帖数: 37081 | 36 都是万恶的媒体！
想当年，Elizabeth为John选举奔前顾后时，小John忙里偷闲还搞出了人命；一朝东窗
事发，还得故作欢颜，为John百般辩解。Elizabeth真是倒霉，生命最后几年，得了BC
、儿子没了、被老公骗了、还要忍受chemo、John的政治生涯也结束了。上天的确很不
公平，此刻Elizabeth也许真的希望能少活那几年，死对她真的是一种解脱。
BTW，老左，问件事。知不知道Elizabeth得的是那种BC？三年就metastasis。 |
|
s**d
发帖数: 325 | 37 《CELL》发表尚永丰教授实验室揭示乳腺癌转移分子机理的研究成果
发布日期：2009-08-27 浏览次数：4952 字号：[ 大 中 小 ]
2009 年8月21日，《CELL》发表北京大学医学部生物化学与分子生物学系尚永丰教
授实验室的研究论文。论文题目为“LSD1 is a Subunit of the NuRD Complex and
Targets the Metastasis Programs in Breast Cancer”（Wang et al, CELL 138:
660-672, 2009. IF 31.253）。王艳博士为第一作者，尚永丰教授为责任作者。
乳腺癌是女性最常见的恶性肿瘤之一，而乳腺癌转移是导致患者死亡的主要原因。
乳腺癌转移的分子机理目前还不完全清楚。LSD1是第一个被发现的组蛋白去甲基化酶，
理论上对基因转录起广泛调控作用，但近期研究却表明LSD1只参与一些特异的细胞信号
通路的调控而且与多种肿瘤的发生发展高度相关，提示这一看似简单的酶在生理病理上
有着复杂的作用机制。尚永丰教授研究小组利用生物化学、分子生物学、 |
|
h*******e
发帖数: 1968 | 38 My good friend in China needs some paper but I cann't find this one in our
school. You know that it's had to do some research in China as graduate
scudents without access to recent papers.
Anybody can help? I guess as long as your university has medical school, you
will be able to find it.
Co-expression of CD44v3 and heparanase is correlated with metastasis of human
colon cancer。
International journal of molecular medicine，2002 Sep;10(3):333-7， Kuniyasu
H, Chihara Y, Kubozoe T, Takahashi T
Thank |
|
c****i
发帖数: 27 | 39 【 以下文字转载自 Biology 讨论区 】
发信人: CaMKII (不作postdog), 信区: Biology
标 题: 最新一期Cell两篇北大的文章（尚永丰&汤超）
发信站: BBS 未名空间站 (Thu Aug 20 12:38:55 2009, 美东)
http://www.cell.com/abstract/S0092-8674(09)00710-7
Cell, Volume 138, Issue 4, 660-672, 21 August 2009
doi:10.1016/j.cell.2009.05.050
LSD1 Is a Subunit of the NuRD Complex and Targets the Metastasis Programs in
Breast Cancer
Yan Wang1,Hua Zhang1,Yupeng Chen1,Yimin Sun1,Fen Yang1,Wenhua Yu1,Jing
Liang1,Luyang Sun1,Xiaohan Yang1,Lei Shi1,Ruifang Li1,Yanyan Li1,Yu |
|
d**********u
发帖数: 4124 | 40 ☆─────────────────────────────────────☆
CaMKII (不作postdog) 于 (Thu Aug 20 12:39:18 2009, 美东) 提到:
发信人: CaMKII (不作postdog), 信区: Biology
标 题: 最新一期Cell两篇北大的文章（尚永丰&汤超）
发信站: BBS 未名空间站 (Thu Aug 20 12:38:55 2009, 美东)
http://www.cell.com/abstract/S0092-8674(09)00710-7
Cell, Volume 138, Issue 4, 660-672, 21 August 2009
doi:10.1016/j.cell.2009.05.050
LSD1 Is a Subunit of the NuRD Complex and Targets the Metastasis Programs in
Breast Cancer
Yan Wang1,Hua Zhang1,Yupeng Chen1,Yimin Sun1,Fen Yang1,Wenhua ... 阅读全帖 |
|
j****u
发帖数: 1413 | 41 新闻与图片花絮请见：http://www.ustcif.org/default.php/content/1605/
加USTCIF为微信好友，即可订阅每日一期中国科大手机新闻报，科大要闻与校友动态尽
在掌握
扫一扫二维码，即可在微信添加好友，每天收到中国科大新闻：
2013年5月2日，肺癌新药发明人、辉瑞公司科学家崔景荣博士（803校友）在北京为中
国
科大校友带来精彩的科普报告《癌症的发生，演变与个体化治疗》。她还介绍她作为主
导发明人的抗癌药克唑替尼 (Crizotinib) 的研发历程，并阐述了她对癌症治疗的抗药
性及抗癌的新理念的看法。
崔景荣领衔的辉瑞公司团队，因发明治疗肺癌新药“克里唑替尼”（Xalkori），2011
年
荣获美国第38届年度国家发明奖，该药2011年在美国上市，之后在北京协和医院、解放
军307医院等地进行中国临床三期实验。2013年，中国食品药品监督管理局（SFDA）批
准
该药在中国上市。
崔景荣介绍癌症的相关基础知识，癌症是细胞生长失控的表现、长期基因突变累积的结
果。她简单列举了诱发癌症的原因，并指出“癌症的复杂性在于癌细胞与周边环境的相
辅... 阅读全帖 |
|
l*****k
发帖数: 587 | 42 This is a pretty cool paper,
1. The experiment they used to show securing binding of P53 affects ability of
P53 to bind DNA, I think it is a long shot to have that conclusion, there are
plenty of other alternative explanations. However, their in vivo experiments
are very convincing.
2. Can anyone tell me how many AA can phage display vectors successfully
express?
A recent paper by ES. Lander and TR. Golub in nature genetics (Jan 2003) “A
molecular signature of metastasis in primary solid tumors” |
|
r****o
发帖数: 105 | 43 本文献给YL
（一）新的开始
去年（２００５）四月份我参加了冷泉港实验室开设的《蛋白质纯化与鉴定》
培训课，并写了“从纯化到星辰”系列短文来回顾这个课程。一开始只是抱着写
着好玩，八卦一下的想法，写到后来整个系列就变成了很严肃的学习笔记。起初
我还担心MITBBS 生物版的网友会觉得这种形式很枯燥无味，没想到大家反应还
挺热情，让我很受鼓励。
“从纯化到星辰”只是开了一个头。今年我想向大家介绍冷泉港实验室开设
的另一个很重要的课程，《小鼠分子胚胎学》(Molecular Embryology of the
Mouse)。之所以今年去学习这门课程是因为我希望利用动物模型来研究复杂的人
类疾病。我一直认为简单的体外实验体系是不可能让我们真正理解人类疾病中出
现的复杂现象的。我举一个简单的例子吧。我做cancer metastasis，研究了两
个有相同遗传背景的人结肠癌细胞株A和B。A是从病人的primary tumor分离出来
的，一年之后这个病人出现癌转移，B是从扩散到淋巴结中的癌症中分离出来的。
我当时就猜想B应该有更强的转移能力。在做细胞培养的时候我注意到B |
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r****o
发帖数: 105 | 44 本文献给YL
（三）五湖四海
《小鼠分子胚胎学》的老师和学生可以说来自五湖四海。主讲老师(instructor)
有两位---UMDNJ的Michael Shen和杜克大学的Blanche Capel。辅讲老师
(co-instructor)也有两位---Stowers的Paul Trainor和北卡的David Threadgill。
Michael 和Blanche在2003~2004是辅讲老师，之后转成主讲，今年则是最后一年执
教这个课。明年就会由Paul和David接班。我博士实验室和Michael 合作过，我还
是他一篇文章的第三作者。前面提过，如果不是因为认识他，我是绝无可能被这
个课录取的。所以我对他是相当感激的。以前虽然合作过，但是我没有见过他。
上了这个课之后才对他有些了解。一开始觉得他有点浮，喝酒之后还会比较疯，
比如跳到桌子上跳舞什么的。但是很快我就发现这老哥在学术上非常牛，分析
问题往往是一针见血。比如metastasis领域还主要停留在用裸鼠xenograft为
研究手段的层次上，Michael则认为这种研究方法完全不对。他的想法和我的
想法可谓是 |
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l******u
发帖数: 936 | 46 Joan Massagué @ sloan kettering |
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b******d
发帖数: 28 | 48 Doug是不是也在作mirna啊？
搞不明白cKO掉dicer后在有些组织内没啥表型，敲出掉17-92却有了。
不是这个方向的，听了doug讲；不是太懂
bob |
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