e*******n 发帖数: 872 | 1 每次都是2个月的时候流的,症状是先出血,然后胎心停了
流产后作了各种检查,发现MTHFR C677T和MTHFRA1298C基因有mutation
请问这两个基因的mutation是造成流产的原因吗?如果是应该如何治疗?有相似的情况
吗? |
|
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L********r 发帖数: 758 | 3 Although your reply is not toward my post, I will try my best to clarify
something for you.
Homosexual behavior is common in prison, but given a freedom of choice, most
of the inmates will choose to intercourse with a partner from different sex
. In your definition, are their sex orientation hetero/homo/bi? In your
thoughts, what caused them to do homosexual behavior? Environment/gene?
And regarding your question of if there is a gene or gene group for
heterosexual preference, it is still hypoth... 阅读全帖 |
|
n****m 发帖数: 1283 | 4 Despite I do not like 8 year father. Talking about who contributed to the
mutation might not help the family.
However, it surely raises more questions. Would it be likely that 8 year
father could not communicate with the genetic consulor?
A professional interpreter might not be able to provide more thorough
description of mutation than 8 year father. |
|
s*******9 发帖数: 177 | 5 高龄产妇, 二胎,等明年生产时已经39了.先做了maternity T21 plus正常。觉得不放
心,在18周时做了一个羊穿,自己掏腰包加选了microarray (这个查得更细,不加选
这个就是普通的羊穿, 心想既然反正做羊穿要扎一针的, 还不如就这个机会做的全面
一些)。 普通的羊穿结果没问题,但是microarray 发现了8号染色体
上多了一小块(8p23.1), 大小大约0.73Mb。
下面是报告的原文, 觉得写的有点模糊:
No diagnostic copy number were observed, however, one variant of uncertain
significance was identified: a heterozygous copy number gain of 0.73 Mb on
8p23.1 (10,875, 772-11,603,171): MIR598,XKR6,MTMR9,SLC35G5,TDH,C8orf12,
FAM167A,BLK,LINC00208, GATA4 (partial).
This region has n... 阅读全帖 |
|
t*******r 发帖数: 22634 | 6 如果你说的是对的,选择性杀戮是最大因子。。。那么 African American
在统计上,应该比非洲不存在黑奴地区的 African 的 intelligence 低
很多。。。有没有数据支持你说的这个?
如果没有数据支持,那我觉得缺乏当年可能在埃塞俄比亚发生的 genetic
mutation 才是第一因子(或者尼派认为尼人的 mutation)。。。虽然
政治上不正确。。。 |
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t*******r 发帖数: 22634 | 7 在人类发明核弹以前,中肯的说,基本还是 mother nature 是第一
选择因子。。。蒙古骑兵那个屠城的搞法,也都没有消灭中原老弱病残,
以及欧洲坑爹贵族。。。另外比如农耕社会后来缺乏大航海,技术就给
退步成那样子。。。
我觉得虽然政治不正确,但是 science 方面,我觉得还是有理由认为
“是不是走出非洲” 可能是第一选择因子。。。大部分 mutation 的走
出了非洲,大部分没有 mutation 的要么懒得走,要么半路就被
mother nature 给 wipe off 了。。。 |
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s*******7 发帖数: 352 | 8 Temporary and Permanent Mutators Lacking the Mismatch Repair System: The
Enhancement of Mutators in Cell Populations
J.H. MILLER, A. YEUNG, P. FUNCHAIN, E. MAO, J. STEWART, W.M. CLENDENIN, and
M.M. SLUPSKA |
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z*h 发帖数: 773 | 9 Brief Introduction of Biofuels Lab at Virginia Tech
“Imagination, Invention, innovation --- Replacing Crude Oil by Sugars
through Cascade Enzyme Factories”. Website: http://sugarcar.com
The mission of the Biofuels Laboratory led by associate professor Yi-Heng
Percival Zhang at Virginia Polytechnic Institute and State University (USA)
is to solve key sustainability challenges – What will replace crude oil?
How and when? How to feed the world in future? Dr. Zhang is a world
recognized young bioc... 阅读全帖 |
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s******i 发帖数: 350 | 10 http://www.news-medical.net/news/20120618/Updated-data-from-ARI
"The pivotal PACE trial data show robust anti-leukaemic activity of
ponatinib in patients with CML at all stages, who are resistant or
intolerant to dasatinib or nilotinib, or who have the T315I mutation, a rare
form of CML which has no available treatment options," said Jane F.
Apperley, professor and chair, Department of Haematology at the Imperial
College, and the chief of service, Clinical Haematology, at the Imperial
College He... 阅读全帖 |
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L****n 发帖数: 12932 | 11 半年的蝌蚪, 能出这种评语,天蝎座也没这么厉害吧。 还有很多...版上比你看得准的
不多了。
INFI昨天可以闻的出有trouble的版上可能没几个。 比HPQ gap down前一天差不多,
但大盘很乱,我可能就会上cover call, 今天还是吃一壶。蝌蚪厉害。
发信人: mutate (mutate), 信区: Stock
标 题: Re: TSLA在狂掉
发信站: BBS 未名空间站 (Wed May 15 09:39:05 2013, 美东)
别担心,昨天滑坡,今天上坡。。。 |
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x******g 发帖数: 984 | 12 已转~
xiaocang,您好:
您转给?mutate,现金(伪币):50,收取手费:0.5同时附加了如下留言给?mutate.求长线
pick,谢大牛美眉 |
|
s*v 发帖数: 275 | 13 siv,您好:
您转给 mutate,现金(伪币):50,收取手续费:0.5
同时附加了如下留言给 mutate.
Qiu pick
站务
已转,谢谢大牛mm |
|
b**********s 发帖数: 435 | 14 已转。谢谢mm!
biosynthesis,您好:
您转给 mutate,现金(伪币):50,收取手续费:0.5
同时附加了如下留言给 mutate.
求pick,谢谢您! |
|
l*******n 发帖数: 773 | 15 寄信人: deliver (自动发信系统)
标 题: 本站转帐通知单
发信站: BBS 未名空间站 (Thu Nov 07 00:51:59 2013)
来 源: mitbbs.com
lilylogon,您好:
您转给 mutate,现金(伪币):50,收取手续费:0.5
同时附加了如下留言给 mutate.
求pick
站务 |
|
L********3 发帖数: 757 | 16 以转,谢谢。
Littlepig3,您好:
您转给 mutate,现金(伪币):50,收取手
续费:0.5
同时附加了如下留言给 mutate.
Qiu pick |
|
u**********n 发帖数: 8905 | 17 紧跟5倍大牛!
umkcmoneyman,您好:
您转给 mutate,现金(伪币):50,收取手续费:0.5
同时附加了如下留言给 mutate.
pick.Thanks!
站务 |
|
e*o 发帖数: 2134 | 18 pm me please
emo,您好:
您转给 mutate,现金(伪币):50,收取手续费:0.5
同时附加了如下留言给 mutate.
pick please |
|
J***J 发帖数: 6000 | 19 紧跟大牛
JJCNJ,您好:
您转给 mutate,现金(伪币):50,收取手续费:0.5
同时附加了如下留言给 mutate.
长线皮克
站务 |
|
o******l 发帖数: 3125 | 20 ontravel,您好:
您转给 mutate,现金(伪币):50,收取手续费:0.5
同时附加了如下留言给 mutate.
pick
站务 |
|
t***u 发帖数: 2057 | 21 已转,谢谢。
寄信人: deliver (自动发信系统)
标 题: 本站转帐通知单
发信站: BBS 未名空间站 (Thu Nov 07 10:19:15 2013)
来 源: mitbbs.com
theyu,您好:
您转给 mutate,现金(伪币):50,收取手续费:0.5
同时附加了如下留言给 mutate.
for pick, thanks
站务 |
|
s********n 发帖数: 125 | 22 已转,学习,thanks
spiritmoon,您好:
您转给 mutate,现金(伪币):50,收取手续费:0.5
同时附加了如下留言给 mutate.
Pick, thanks
站务 |
|
d******b 发帖数: 105 | 23 寄信人: deliver (自动发信系统)
标 题: 本站转帐通知单
发信站: BBS 未名空间站 (Thu Nov 07 11:30:00 2013)
来 源: mitbbs.com
dewitchb,您好:
您转给 mutate,现金(伪币):50,收取手续费:0.5
同时附加了如下留言给 mutate.
qiu pick |
|
h********2 发帖数: 433 | 24 houston312,您好:
您转给 mutate,现金(伪币):50,收取手续费:0.5
同时附加了如下留言给 mutate.
Please share your pick. Thanks |
|
o********d 发帖数: 1070 | 25 oldmanhead,您好:
您转给 mutate,现金(伪币):50,收取手续费:0.5
同时附加了如下留言给 mutate.
Pick please |
|
c******3 发帖数: 35 | 26 coolin83,您好:
您转给 mutate,现金(伪币):50,收取手续费:0.5
同时附加了如下留言给 mutate.
谢谢pick。
站务 |
|
s********n 发帖数: 317 | 27 sundaymoon,您好:
您转给 mutate,现金(伪币):50,收取手续费:0.5
同时附加了如下留言给 mutate.
大牛 求pick 谢谢 |
|
H****7 发帖数: 159 | 28 HD2007,您好:
您转给 mutate,现金(伪币):50,收取手续费:0.5
同时附加了如下留言给 mutate.
Pick, thanks.
站务 |
|
x*j 发帖数: 271 | 29 xmj,您好:
您转给 mutate,现金(伪币):50,收取手续费:0.5
同时附加了如下留言给 mutate.
buy the pick
站务 |
|
N*****d 发帖数: 9872 | 30 盘后是五倍大牛坐的庄?依稀记得数年前五倍大牛一个金矿股盘前传出被收购消息暴涨
50%,几个月后就归零了
[在 mutate (mutate) 的大作中提到:]
:盘后5.5了,牛牛们冲! |
|
N*****d 发帖数: 9872 | 31 想起来了,那个股叫anv
The ANV (Allied Nevada Gold Corp) Active Long Trade is halted today on news
of a buyout offer at 7.50/share, which is also my final target (T2).
Although there is some buzz about the stock being valued at over $9.00 share
(click here to view article), T2 remains my final target and the trade will
be considered completed, should the stock trade at 7.50 or higher upon
opening. The live chart of ANV can be viewed by clicking here (although as
of the time this post was publish, the st... 阅读全帖 |
|
s*******9 发帖数: 177 | 32 高龄产妇, 二胎,等明年生产时已经39了.先做了maternity T21 plus正常。觉得不放
心,在18周时做了一个羊穿,自己掏腰包加选了microarray (这个查得更细,不加选
这个就是普通的羊穿, 心想既然反正做羊穿要扎一针的, 还不如就这个机会做的全面
一些)。 普通的羊穿结果没问题,但是microarray 发现了8号染色体
上多了一小块(8p23.1), 大小大约0.73Mb。
下面是报告的原文, 觉得写的有点模糊:
No diagnostic copy number were observed, however, one variant of uncertain
significance was identified: a heterozygous copy number gain of 0.73 Mb on
8p23.1 (10,875, 772-11,603,171): MIR598,XKR6,MTMR9,SLC35G5,TDH,C8orf12,
FAM167A,BLK,LINC00208, GATA4 (partial).
This region has n... 阅读全帖 |
|
a*******1 发帖数: 1187 | 33 【 以下文字转载自 Pharmaceutical 讨论区 】
发信人: bald (小颓), 信区: Pharmaceutical
标 题: 新泽西公司找有genomics背景的PhD Scientist (转载)
发信站: BBS 未名空间站 (Wed Nov 3 21:40:30 2010, 美东)
发信人: bald (小颓), 信区: Biology
标 题: 新泽西公司找有genomics背景的PhD Scientist
发信站: BBS 未名空间站 (Wed Nov 3 21:06:35 2010, 美东)
公司在找有genomics背景的PhD Scientist.我们是service company,做大量的SNP/
mutation analysis.希望你熟悉 how to look for genomic sequence in the
database, PCR primer design, PCR sequencing data analysis and call mutation/
insertion/deletion etc.如果你有分子生物学的背... 阅读全帖 |
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s*******9 发帖数: 177 | 34 高龄产妇, 二胎,等明年生产时已经39了.先做了maternity T21 plus正常。觉得不放
心,在18周时做了一个羊穿,自己掏腰包加选了microarray (这个查得更细,不加选
这个就是普通的羊穿, 心想既然反正做羊穿要扎一针的, 还不如就这个机会做的全面
一些)。 普通的羊穿结果没问题,但是microarray 发现了8号染色体
上多了一小块(8p23.1), 大小大约0.73Mb。
下面是报告的原文, 觉得写的有点模糊:
No diagnostic copy number were observed, however, one variant of uncertain
significance was identified: a heterozygous copy number gain of 0.73 Mb on
8p23.1 (10,875, 772-11,603,171): MIR598,XKR6,MTMR9,SLC35G5,TDH,C8orf12,
FAM167A,BLK,LINC00208, GATA4 (partial).
This region has n... 阅读全帖 |
|
s*******9 发帖数: 177 | 35 高龄产妇, 二胎,等明年生产时已经39了.先做了maternity T21 plus正常。觉得不放
心,在18周时做了一个羊穿,自己掏腰包加选了microarray (这个查得更细,不加选
这个就是普通的羊穿, 心想既然反正做羊穿要扎一针的, 还不如就这个机会做的全面
一些)。 普通的羊穿结果没问题,但是microarray 发现了8号染色体
上多了一小块(8p23.1), 大小大约0.73Mb。
下面是报告的原文, 觉得写的有点模糊:
No diagnostic copy number were observed, however, one variant of uncertain
significance was identified: a heterozygous copy number gain of 0.73 Mb on
8p23.1 (10,875, 772-11,603,171): MIR598,XKR6,MTMR9,SLC35G5,TDH,C8orf12,
FAM167A,BLK,LINC00208, GATA4 (partial).
This region has n... 阅读全帖 |
|
O***n 发帖数: 13127 | 36 mutation, mutation, evolution, evolutions after thousands of years
btw, how old is 苏轼? |
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s*****g 发帖数: 3693 | 37 Plants' DNA is accumulation of last 百万年发生的基因变异. DNA has been
duplicated, shuffled, mutated, lost from the genome and exogenous DNA
fragments from other plant species, bacteria, fungus and virus were
transferred into plant genome as well. All those happened naturally.
Current plants should be considered super "genetically modify" when compared
to their ancestors.
Domestication of crops is a process of selecting DNA mutations beneficial to
human. Genetic engineering is doing exactly the same.
... 阅读全帖 |
|
F*V 发帖数: 3978 | 38 大棋局与9/11
来源: ognc 于 2013-02-22 16:08:44[档案] [博客] [旧帖] [转至博客] [给我悄悄
话] 本文已被阅读:63次
字体:调大/调小/重置 | 加入书签| 打印| 所有跟帖 | 加跟贴| 查看当前最热讨论主题
The Moral Decoding of 9-11
By Prof. John McMurtry
(Journal of 9/11 Studies) - I was sceptical of the 9-11 event from the first
time I saw it on television. It was on every major network within minutes.
All the guilty parties were declared before any evidence was shown. The
first questions of any criminal investigation were erased. Who had the most
compelling motives for... 阅读全帖 |
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G***G 发帖数: 16778 | 39 早期的人类胎形和老鼠的,鱼的胎形很相近,都有尾巴和脊骨。
那么会有哪些因素导致几周后胎形的不同的呢?
1)基因
2)不解码的基因
3)蛋白质
4)调控机制
另外,我还有一个很基本的生物问题。关于鱼的。
单细胞生物,细胞质内就是dna。细胞分裂,dna复制,这个单细胞生物就长大了。
毫无疑问,每个细胞,每个细胞里的dna都是相同的(假设没有mutation)。
但是对于多细胞生物。最早就是fertilized egg. 就一个细胞。
这1个细胞怎么能分裂成多种多样的细胞,从而让某些细胞组成不同的organ。
如果从不同organs里面取出dna,比如liver, brain。
那么如果进行基因测序的话,liver里面和brain里面是不是应该完全一样的
dna序列(不考虑mutation)?
但是如果我们进行基因芯片分析,或者next generation sequencing,
我们能找到differentially expressed gene across organs。
这是不是说明liver和brain里面的dna序列都是存在的,而且是一模一样的。
但是有的organ里面表达得... 阅读全帖 |
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发帖数: 1 | 40 I was thinking to go for the mutation quest for unlock, so changed focus to
start bnw instead.
but then I saw there is a command line to enable the mutation, need to try
try tomorrow.
btw, the first innkeep at bnw has really strong kunte deck. and it looks
like many new cards to be collected. |
|
e****i 发帖数: 2152 | 41
engineer的飞船里那些罐子里黑色的液体 is not 异型幼虫的培养液. It mutates the
organism it infects. What comes out of the mutation depends on the organism
being infected. |
|
x****u 发帖数: 12955 | 42
If you recognize GMF and drugs are different, then why always say they are
both managed by FDA? They have commonalities, sure. But you will find
commonalities in almost everything we see, touch, hear, and use. That doesn
't make them equivalent or should subject to the same regulations. The fact
is, GMF so far are concentrating on transferring genes to reproduce
naturally occurring substances. If there is area of concern, it's about
what happens when the transferred genes mutate within the... 阅读全帖 |
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t**n 发帖数: 244 | 43 你说“不是。“,然后把我的话说一边。你说的是natural selection大部分是random
; 我说的是 mutation是random,natural selection不是,是survival of the
fittest。“mutation在达尔文的进化论中是提供natural selection的资源或材料而已
“是我的观点。所以random在natural selection之前。
中性进化论?改基因食品是中性进化?自然选择不起作用?中性进化论阐明了分子水平
上的进化机制,这种机制主要在于中性突变本身,是生物分子随机的自由组合,自然选
择不起作用,分子进化的方向与环境无关。中性突变三种类型:1有一个核苷酸发生置
换,往往不会造成氨基酸的改变。2非功能性DNA顺序的突变对蛋白质的合成没有影响。
3结构基因的突变,不影响蛋白质原有的主要功能。 |
|
f****p 发帖数: 18483 | 44
http://bbs.tianya.cn/post-funinfo-4023670-12.shtml
摘录如下。可惜了,好歹也算当过我徒弟了。。。
附录2:吐了大妈的简历
Haiying Zhou's Education
postdoc at University of California at Berkeley
San Francisco Bay Area
Research
Haiying Zhou's Education
The University of Texas Health Science Center at San Antonio
Ph.D., Molecular Medicine
2001 – 2008
Nankai University
B.S, Chemistry
1993 – 1997
Haiying Zhou's Publications
Dual functions of TAF7L in adipocyte differentiation
eLIFE
January 8, 2013
Authors: Haiying Zhou
The diverse tr... 阅读全帖 |
|
M****0 发帖数: 877 | 45 以下是ld用我的ID给别人回的帖子,转一下,可能对你有点帮助。
今天有点空,用ld的ID上来帮你分析一下。
First, you need to know the stage (as you mentioned your uncle has
adenocarcinoma which belongs to non-small cell lung cancer. If is small cell
lung cancer, it will be a different story). For most of stage I and II,
even some IIIA, the intent for treatment is cure.
If your uncle's lung cancer is just 2.5 cm and no metastases, then his
cancer is stage IA. This stage can be cured with surgery only, followed by
imagine surveillance. But he does ... 阅读全帖 |
|
d****g 发帖数: 93 | 46 most Asian lung Adc are casue by EGFR mutation. Please have your mum tumor
sequenced.If it is driven by EGFR mutation, please consider Taceva or some
other TKI. |
|
d**********o 发帖数: 1321 | 47 第二次作业补充说明(2)
那么fit出二次函数的难点在哪里呢?笔记本内存硬件要求,和C++资源管理,如果是用
c++编程的话,用java当然就没有这个问题了。
这个genetic programming的项目,我的constructor, destructor都是没有问题的;其
它地方可能会占用资源的的就是,当我每一代(generation)选出两个 elite
individuals 作为parent,我用steady-state的方法,先把它们考贝到两个worst
individuals的位置(保存一个最好版本),再将 elite individuals 突变,node
mutation,这一步那两个worst individuals的资源我是释放了的,node mutation并不
占用资源,所以我认为自己的资源管理是没问题的。可我的linux mint大胡子帮我装的
是32 bit的,内存就很少。加上这种进化,因为crossover的发生,tree的size增长得
非常快。这样导致的直接结果就是,每次程序上百万个generation 一路run下来,不等
程序正常结束,就会有“... 阅读全帖 |
|
d**********o 发帖数: 1321 | 48 第二次作业补充说明(2)
那么fit出二次函数的难点在哪里呢?笔记本内存硬件要求,和C++资源管理,如果是用
c++编程的话,用java当然就没有这个问题了。
这个genetic programming的项目,我的constructor, destructor都是没有问题的;其
它地方可能会占用资源的的就是,当我每一代(generation)选出两个 elite
individuals 作为parent,我用steady-state的方法,先把它们考贝到两个worst
individuals的位置(保存一个最好版本),再将 elite individuals 突变,node
mutation,这一步那两个worst individuals的资源我是释放了的,node mutation并不
占用资源,所以我认为自己的资源管理是没问题的。可我的linux mint大胡子帮我装的
是32 bit的,内存就很少。加上这种进化,因为crossover的发生,tree的size增长得
非常快。这样导致的直接结果就是,每次程序上百万个generation 一路run下来,不等
程序正常结束,就会有“... 阅读全帖 |
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