a***c 发帖数: 578 | 1 runner's world上的一篇老文章,大概意思是止痛药的使用要适量,主要危害是kidney
and high blood pressure,不同的止痛药用量不同,最后针对不同的伤病推荐了不同
的止痛药,相对来说,acetaminophen(Tylenol)要安全点,但效果也可能差些
http://www.runnersworld.com/injury-treatment/pill-problem?page=
The Pill Problem
After winning a 24-hour track run in record time, Stephanie Ehret should
have been celebrating. Instead, she was in a Phoenix emergency room,
vomiting up a strange substance, which a doctor informed her was part of her
digestive-tract lining. Feverish and nauseous, Ehret co... 阅读全帖 |
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b***m 发帖数: 2112 | 2 最近做功课研究消除疼痛的办法,看到下面这边文章。大意似乎是:
1)炎症是身体对抗伤痛的自然反应,是身体自我修复过程的正常症状;
2)药物消除炎症,同时也抑制了身体的自我修复过程,反而不利于伤痛的恢复;
3)消炎药不能明显提高比赛成绩。
根据这篇文章的说法,我觉得ibuprofen或Advil最大的效果可能是止痛(类似麻醉剂,
消除或削弱大脑对疼痛的感受)。疼痛要求人不要过度使用身体;大脑不觉得疼了,就
会继续正常(其实是超量)使用身体。后果可能是短时间内保持了成绩,但加速了肌肉
撕裂,伤病加重。
我英语不太好,英语好的可以再总结一下。
Ibuprofen and Running
Written by Coach Jeff
As a competitive runner and a coach, I am always striving to find the
perfect balance between recovery and adaptation.
If you’re reading this post, you too have probably come across you... 阅读全帖 |
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b***i 发帖数: 10018 | 3 ☆─────────────────────────────────────☆
AiUWa (Nemo妈) 于 (Tue Feb 28 14:53:48 2012, 美东) 提到:
上个礼拜左glute痛,休息。养了2天没感觉了。去跑步,左膝盖痛,决定休息一个礼拜
,其实才一天后就不痛了。但是我是小心出名的,所以继续养着。
书其实还没看完。看到一半的地方吧。
一些完全没有organize好的想法。
1. 在还没看书之前,测了一下平时easy long run的心跳。136-146之间。然后看书知
道怎么算MATHR.发现我如果take on LHR training的话。心跳要保持在134-144之间。
所以自己最舒服状态跑步差不多就是他建议的那样了。但是想想次次出门跑步都要像
easy long run的pace.没有speedwork,tempo, 难道不会很boring么?
2. 他说在build up aerobic base之前,任何anaerobic运动都会有坏影响。这点非常
turn me off.
3. 作者说用MAF办法,并且配合良好的饮食,压力控制好之类。... 阅读全帖 |
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n******a 发帖数: 6 | 4 Cortisone ,Celebrex 都是处方药,怎搞?
唉,看来老妈的病是没法治了
从某处转载的:
Analgesics (pain relievers) such as acetaminophen (Tylenol)* and nonsteroidal
anti-inflammatory drugs (NSAIDs) such as ibuprofen are used to reduce the pain
caused by many rheumatic conditions. NSAIDs have the added benefit of
decreasing the inflammation associated with arthritis. A common side effect of
NSAIDs is stomach irritation, which can often be reduced by changing the
dosage or medication. New NSAIDs, including celecoxib (Celebrex) and |
|
l***h 发帖数: 9308 | 5 我记得以前给过一个术语链接在某个置项贴里面,可能归档了吧,再贴一下,新人不懂
的可以参考一下
http://www.runnersworld.com/community/forums/runner-communities
Your friendly beginning runner's guide to .... runner's jargon.
You'll notice we don't have a FAQ here -- that's because we want you to ask
your questions, join in, become part of the community! That said, I am sure
new runners get overwhelmed by phrases we throw around all the time here
with impunity; you probably think we're all speaking some strange language.
To follow along here, ... 阅读全帖 |
|
W***i 发帖数: 833 | 6 算了,我还是再贴一遍,
Your friendly beginning runner's guide to .... runner's jargon.
You'll notice we don't have a FAQ here -- that's because we want you to ask
your questions, join in, become part of the community! That said, I am sure
new runners get overwhelmed by phrases we throw around all the time here wit
h impunity; you probably think we're all speaking some strange language. To
follow along here, it's really helpful just to know some general stuff and w
hat terms mean. So in the interest of hel... 阅读全帖 |
|
l***h 发帖数: 9308 | 7 marathon pace
跑步黑话大全
Your friendly beginning runner's guide to .... runner's jargon. Cool
You'll notice we don't have a FAQ here -- that's because we want you to ask
your questions, join in, become part of the community! That said, I am sure
new runners get overwhelmed by phrases we throw around all the time here wit
h impunity; you probably think we're all speaking some strange language. To
follow along here, it's really helpful just to know some general stuff and w
hat terms mean. So in the in... 阅读全帖 |
|
l******k 发帖数: 27533 | 8 哈哈,赞!
凭印象补充下NSAIDs对肾和血压的影响
NSAIDs constrict afferent arterioles of glomerulus, which may cause fluid
retention and therefore increase BP.
严重的情况是NSAIDS-LISINOPRIL-LOOP DIURETIC TRIAD contraindication
另外一种说法是NSAIDs有其他未知机理影响anti-hypertensive drugs efficacy like
beta blockers and thiazides... |
|
l******k 发帖数: 27533 | 9 哈哈,赞!
凭印象补充下NSAIDs对肾和血压的影响
NSAIDs constrict afferent arterioles of glomerulus, which may cause fluid
retention and therefore increase BP.
严重的情况是NSAIDS-LISINOPRIL-LOOP DIURETIC TRIAD contraindication
另外一种说法是NSAIDs有其他未知机理影响anti-hypertensive drugs efficacy like
beta blockers and thiazides... |
|
y*********c 发帖数: 1014 | 10 Try OTC NSAIDS such as ibuprofen for the pain first before going to doc.
They will most likely to prescribe you a stronger strength of NSAIDs to take
. Do you use computer a lot? Do you have numbness of your hand? If yes, you
may have carpal tunnel syndrome. Otherweise, just take NSAIDs if you don't
have cardiac disease. You would be fine. |
|
L********9 发帖数: 85 | 11 If anyone has GI history, such as ulcers, please be careful of NSAIDS.
NSAIDS includes Motrin (Ibuprophen), Aleve, Naproxen... NSAIDS can cause GI
bleeding if it's used excessively. |
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g*2 发帖数: 658 | 12 那就排除炎性,免疫性的原因,还有滑囊炎。感觉patellofemoral pain syndrome
PFPS 或是 patellar tendinopathy, 前者可能性更大些
前者:
PFPS is the most common etiology of anterior knee pain in the general
population. PFPS can be defined as pain involving the patella and
retinaculum that excludes other intraarticular and peripatellar pathology.
There is no consensus about its pathophysiology. Overuse is common among
patients with PFPS.
PFPS has no pathognomonic sign or symptom. PFPS is a clinical diagnosis made
based upon history, exam... 阅读全帖 |
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c****n 发帖数: 21367 | 13 同一套原则下,没有啥进步,一次又一次重复而已
要不你说说新的NSAIDs和老的NSAIDs能有啥不同?
从老的NSAIDs里得到了模型的改进么? |
|
g*****j 发帖数: 1211 | 14 Cerebrex is an COX2 NSAIDs. NSAIDs are used in almost all joint and
musculoskeletal pain. Lupus arthritis is a joint disease caused
specifically by an antoimmune disorder. When in active disease, patient
can experience terrible pain in joints as well as injuries to other
vital organs. If the patient has active lupus, doctor will not only
prescribe Cerebrex. If the patient is only taking Cerebrex, that
means his doctor thinks that his lupus was in good control during the
last visit. As a ma... 阅读全帖 |
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s**********e 发帖数: 2888 | 15 骗局一: 西医说止痛药没有副作用,或是只有说明书上写出的那些副作用;
现有的止痛药,包括传统的NSAIDs,现在的争议很大的COXIBs,这两类都是cox-2抑制剂
。从来没有说过自己没有副作用,或者只是说明书上的副作用。NSAIDs开始的时候认为
会抑制cox-1和cox-2,认为会产生消化系统的副作用,后来开发了非常选择性的cox-2
抑制剂,就是COXIBs,结果后来发现了心血管系统的副作用。关于NSAIDs/COXIBs的副
作用的研究,文章太多了。
但是呢,这些副作用,都是大剂量长期使用才会很明显。比如Merck自己撤掉的Vioox,
现在有很多的呼声希望它重新上市,因为如果严格的使用,或者只在某些特定的sub-
population patients使用,副作用是可以控制的,这类药物对于关节炎又非常好的作
用。
你说的这些话,完全是胡话。
骗局二: 止痛药能治好你的病;
你说的这句话,我都不知道怎么反驳你。谁他妈说过止痛药可以只好你的病?你在那里
听到的?
但是最近的研究,证实了某些止痛药,对于很多类型的癌症,有非常好的预防作用。原
因是因为,cox-2在很多的癌症细胞... 阅读全帖 |
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w**********u 发帖数: 290 | 16 今儿下午准备推荐信闹心,看到Daisyy在组织CS talk,我也来写写我的经验,算是加
把柴吧!
我是CK考完后一个半月考的,准备的书只用了FA,上了NJ两天班,感谢后来的partner
订了严格的计划使得能够把FA过到两遍,准备过程中觉得最重要的就是练习练习再练习
。第一遍的时候比较茫然,但是就跟着FA练,等到第二遍的时候严格控制时间和PN的练
习,感觉就来了。反正无时无刻的练习,把嘴张开,然后像模像样的象征性的做体检就
对了。我最后的几天找了GoldUSMLEREVIEW做了mock practice,有用没用不说,至少是
让我安了心,说我能去考了。Authur怎么样不知道,因为我约的太晚了。
考试时:
1. 我有两例没顾上closure,就出去了,现在看来两例问题不大。
2. 考试时戴的手套,方便,还能一边戴一边问问病人心情如何,或者说我手凉云云。
3. 有些药物实在是听不懂啊,重复问了一遍,还是没懂,但是我知道肯定是某类
NSAIDS,PN上直接写了NSAIDS。后来凡遇到者不再重复问,直接写NSAIDS.
4. PN有一个没写完,Social 和sexual history... 阅读全帖 |
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m******r 发帖数: 1904 | 17 ☆─────────────────────────────────────☆
watermelonxu (dolphin) 于 (Fri Jul 6 17:58:02 2012, 美东) 提到:
今儿下午准备推荐信闹心,看到Daisyy在组织CS talk,我也来写写我的经验,算是加
把柴吧!
我是CK考完后一个半月考的,准备的书只用了FA,上了NJ两天班,感谢后来的partner
订了严格的计划使得能够把FA过到两遍,准备过程中觉得最重要的就是练习练习再练习
。第一遍的时候比较茫然,但是就跟着FA练,等到第二遍的时候严格控制时间和PN的练
习,感觉就来了。反正无时无刻的练习,把嘴张开,然后像模像样的象征性的做体检就
对了。我最后的几天找了GoldUSMLEREVIEW做了mock practice,有用没用不说,至少是
让我安了心,说我能去考了。Authur怎么样不知道,因为我约的太晚了。
考试时:
1. 我有两例没顾上closure,就出去了,现在看来两例问题不大。
2. 考试时戴的手套,方便,还能一边戴一边问问病人心情如何,或者说我手凉云云。
3. 有些药物实在是听... 阅读全帖 |
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y******a 发帖数: 590 | 18 if it's ankylosing spondylitis:
first line treatment- physical therapy, NSAIDs if patient has inflammatory
back pain or other joint pain
if not respond to NSAIDs (have tried three different NSAIDs, still have pain
), try TNF alpha inhibitor, like infliximab, adalimumab, or eternacept. No
study so far demonstrated any difference of these three meds.
NO disease modifying medications so far, based on current available trials.
If it's other seronegative spondylitis, like psoriatic arthritis or... 阅读全帖 |
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f******I 发帖数: 769 | 19
for acute phase any NSAIDS would do, but in particular indocin or colchicine
, for indocin be careful if patient has kidney disease or gastrointestinal
ulcer and it might also induce neutropenia, for colchicine it could cause
very bad diarrhea,
if patient is not a good candidate for NSAIDS then steroid, either systemic
or intra-articular,
for long term maintainence take allopuirnol, which should be dosed according
to renal function and do not take it till acute attack abates for a couple
weeks, |
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t*******n 发帖数: 4445 | 20 Asprin, ibuprofen and naproxen are NSAID drugs which often irritate the
stomach. Tylenol is not an NSAID and is pretty safe in this regard. |
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g*****j 发帖数: 1211 | 21 This is called dysmenorrhea.
If the pain occurs during onset of menses, the most likely cause is primary
dysmenorrhea, which usually will respond to nonsteroid anti-inflammatory
drugs (NSAIDs) such as motrin. You can give it a try next month. Remember
that it has to be NSAIDs, and tylenol does not work.
If the pain is really intolerable or motrin makes no difference at all, you
need to see a physician, preferably an OB/Gyn doctor. If you search
dysmenorrhea online, you will find many potenti |
|
g*****j 发帖数: 1211 | 22 The only medicine that does not need prescription are pain killers during
acute attack, such as Tylenol and NSAIDs (ie Naproxen, Ibuprofen).
Major treatment for gout in acute phase include: NSAIDs, colchicine,
corticosteroid, for long term treatment include: allopurinol, probenecid.
All of them need prescription. |
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g*****j 发帖数: 1211 | 23 The only thing you can get OTC is probably non-steroid anti-inflammatory (
NSAIDs), such as motrin, naproxen etc. Gout in acute phase can be very
painful, and NSAIDs may not be sufficient. More effective drugs will need a
prescription. |
|
a**********2 发帖数: 3726 | 24 Hard to say. The diagnosis of bone tumor is sometimes very tough to make. X
ray, bone scan, only provides possibility, even pathology (biopsy) sometimes
can not confirm the diagnosis.
Lets say if it is, with current 2 year of survival without obvious
metastasis or local invasion, it sounds benign or low grade malignancy.
As for the anti inflammatory meds (NSAIDS), it helps for some patients
Or early stage of pain management, but you can't judge that it is not bone
tumor because the pain can be c... 阅读全帖 |
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b******8 发帖数: 1251 | 25 colchicine, NSAID, corticosteroid are equally efficient for gouty attack. 你
就用NSAID就是了,非处方的药,就买ibuprofen就是了,按照anti-inflammatory的计
量吃,800mg 每天3次或者4次,200mg的是非处方,买了按照800mg 这样吃就是了,做
个算数就是。 |
|
s*******k 发帖数: 3071 | 26 ☆─────────────────────────────────────☆
NSAID (大印象) 于 (Fri Aug 6 14:11:06 2010, 美东) 提到:
从7/28 167lbs开始到今天 8/7 165lbs,虽然一直维持低卡饮食,体重只掉了两磅。我
估摸着,可能这就是平台了。
怎么办呢? 是维持原来的低卡,甚至于更低? 还是低卡+运动?
运动是我的死穴,如果实在要运动,恐怕就是晚上10点以后去24hrs fitness了,想想
就头疼阿。
请有过相同经历的兄弟姐妹们出出主意吧。
☆─────────────────────────────────────☆
kittykitty (白雪公主) 于 (Fri Aug 6 14:16:05 2010, 美东) 提到:
可以吃完晚饭在家附近走路
☆─────────────────────────────────────☆
NSAID (大印象) 于 (Fri Aug 6 14:32:10 2010, 美东) 提到:
我晚饭基本不吃的。饭后时间如果不是在上班的话,就是在陪儿子们打篮 |
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g*2 发帖数: 658 | 27 一般痛经和前列腺素(prostaglandin)的分泌有关, 吃些OTC的NSAIDs (非甾体类消炎
药,如 Motrin)就好了。 但因为主要有胃肠道,心,还有肾的副作用,尽量少服用。
用理疗的方法加休息就好了。
另外,月经期,盆腔充血,尽量避免非常剧烈的运动。少量运动是可以的,也有助于放
松。
如果吃Motrin等NSAIDs, 要注意避免脱水, 因为它会收缩肾前小动脉,加上脱水会加
重对肾的影响。 这适应于所有服该药的人。 |
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l*****g 发帖数: 138 | 28 不是麻醉剂,是NSAID,抗炎症的,跟Advil的作用原理一模一样,但是口服的话,一方
面没法精准施加到膝盖,另一方面NSAID对消化道黏膜伤害非常大。药膏就把这两个问
题都解决了。
我感觉有些慢性炎症一旦发生了,可能因为局部肿胀变形,所以会一直受到刺激,就总
是很难自己恢复,哪怕当初造成炎症的诱因已经不存在了,尤其是关节这样一个不停活
动的地方。需要一个外界的因素来把它压制一段时间才好。RICE大法就是尽量抑制炎症
的,不过现在看来还是不如直接用药效果好。
另外,我在google voltaren gel的时候,发现有人用它来对付脚底筋膜炎,效果貌似
也不错。 |
|
m******4 发帖数: 2810 | 29 你这种情况我见过很多呀,好长时间不踢,一踢还特兴奋,当场吐的,中途不行了回家
的都有,你这一踢就上比赛,踢完才犯毛病已经算不错了。
我不是医生啊,后果自负。我以前关节有inflammation,医生给我开的NSAID类处方药
,但是医生说用普通的NSAID,比如Advil就可以。我当时情况应该比你严重,连续吃了
八天处方药,大概四五天后有明显好转。你要是没打算看医生又想快点儿恢复吃Advil
会有帮助。 |
|
z***a 发帖数: 8436 | 30 maria好久不见了呀,呵呵
成分太多,我比较忙,没有每个查。
不过好像看到有回帖说含有asprin.提醒你一下,asprin是NSAIDS,因为anti coagulant
and COX-2 inhibition 的作用而起到活血止痛作用。但是因为是NSAIDS,对胃出血等副作
用是靠take with meal不能防治的。它主要是抑制了COX-1 PATH,破坏了COX-1保护消化道黏
膜的功能而产生消化道出血或者溃疡的。所以,你要是本身就有溃疡,不能用。
还有跟剂量关系很大。而植物药很难做到剂量准确。建议你先试试baby asprin (81 mg
)。如果能起到同样的效果,这个就很好。如果是其他植物成分在调节,那就换回这个植物药
也不错。不过如果出现胃痛,出血等症状,要马上停用。
willow bark, |
|
b*******y 发帖数: 12791 | 31 OTC止痛片常见的分三种
Acetaminophen (对乙酰氨基酚,扑热息痛)。最常见的就是brand name就是Tylenol
。这一类止痛片存在时间很长,是最常用的止痛片之一。好处是相对副作用小,对肠胃
刺激小。坏处是对肝肾的负担大。如果肝肾功能有问题的要慎用。
Ibuprofen (布洛芬)。常见brand name是Motrin, Advil。消炎,退烧,止痛效果多
不错
Naproxen。常见的brand name是Aleve,Midol。药效长,需要吃的量少。Midol有专门
针对 menstral cramp的
Ibuprofen和Naproxen都是onsteroidal anti-inflammatory drugs (NSAIDs)。NSAIDs
类药物对肠胃刺激大,最好和食物一起服用,减少药物对肠胃的直接刺激,特别是如果
有恶心的症状。另外这类药会增加心脏病和中风的可能性。 |
|
c****n 发帖数: 21367 | 32 nah,反复强调我不是中医fan了 :)
你也承认这个是局限性,那我们没啥分歧
不过也说句实在话,在经济利益的驱动下,FDA是绝对不会在
短期内制订标准使得药检的数据具有通用性,建立模型的。
因为这个会打破药厂的垄断。
科学指明了路,但未必能赚钱。呵呵。
只有在同一个模型下,数据积累和改进才是对人类医疗研究的
真正促进。只有这样,一个NSAIDs这样和预期不符的效果,
才能反映到模型的改进上,使得一类药物都不会被研发,
新的NSAIDs产生的概率变小。 |
|
S******1 发帖数: 44 | 33 今天得知了step3的成绩,210+,心里的石头终于落下。终于轮到我给USMLE说再见了。
回顾从step1自己闭门造车考了只带一个9的分数, step2开始参加小组学习,做了所有
能做的题只为拿个99,虽胸有成竹且考试感觉很好,最终但又得到一个9的分数。虽然
这次成绩不高,依然很高兴,毕竟不用发愁如果没过的话住院医开始后没有时间复习该
咋办。过去的3年中得到太多人的帮助 (此处略去人名20个),绝大多数甚至从未谋面。
今天发贴也是为了回报我们这个社区吧。
自我介绍:毕业>15年,220+/220+/1st/210+;
复习时间:6月,头4个月每天约2-3小时,周末由于陪孩子们玩(前两年欠的太多,你
懂得)及做点家务(再不做但心被老婆炒掉),反而复习不了多少;最后2个月每天4小
时,鼓励自己考了这个2年内再不用受这个罪。
复习资料:随大流,MTB 3, UW CCS, UW step3 Qbank, UW step2 Qbank;
模拟:考前2月,NBME 1 190+, 考前1周,NBME 2 220+;
体会:难,考过不容易,考高分更难。主要是因为没有合适的复习资料。UW的1300... 阅读全帖 |
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r********r 发帖数: 352 | 34 我觉得你记反了。
E for exit没错,不过kidney perfusion requires vasodilation of afferent blood
vessel and vasoconstriction of efferent blood vessel (想像一个管子,进口要
大,出口要小,这样管子里才有足够的水压,如果进口小,出口大,就没水压了,不是
吗) vasodilation of afferent blood vessel requires prostaglandins, so
NSAIDs inhibits the vasodilation.
ACEI causes vasodilation of efferent blood vessel, buy it self, this
mechanism is very good for lowering BP and protecting the kidneys, but with
the combination of NSAIDs, it may cause kidney injury, especially ... 阅读全帖 |
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u*******s 发帖数: 688 | 35 好,理清楚了:
Afferent arteriole: maintained in vasodilated state by prostaglandins
Efferent arteriole: maintained in vasoconstricted state by Angiotensin II
NSAID: block PG and cause vasoconstriction of afferent
ACE-I: block AG-II and cause vasodilation of efferent.
Concomitant use of NSAID, ACE-I, LOOP can cause acute renal failure. |
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r********r 发帖数: 352 | 36 我觉得你记反了。
E for exit没错,不过kidney perfusion requires vasodilation of afferent blood
vessel and vasoconstriction of efferent blood vessel (想像一个管子,进口要
大,出口要小,这样管子里才有足够的水压,如果进口小,出口大,就没水压了,不是
吗) vasodilation of afferent blood vessel requires prostaglandins, so
NSAIDs inhibits the vasodilation.
ACEI causes vasodilation of efferent blood vessel, buy it self, this
mechanism is very good for lowering BP and protecting the kidneys, but with
the combination of NSAIDs, it may cause kidney injury, especially ... 阅读全帖 |
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u*******s 发帖数: 688 | 37 好,理清楚了:
Afferent arteriole: maintained in vasodilated state by prostaglandins
Efferent arteriole: maintained in vasoconstricted state by Angiotensin II
NSAID: block PG and cause vasoconstriction of afferent
ACE-I: block AG-II and cause vasodilation of efferent.
Concomitant use of NSAID, ACE-I, LOOP can cause acute renal failure. |
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s******v 发帖数: 477 | 38 现学现卖,接着卖弄
drug eruptions ( sorry, I can only cover a small part of this):
1.Any drugs is capable of cutaneous lesions, for any rash consider drug
eruption.
2. The usual suspects: antimicrobiasis, ( PCN< Sulfonamides..), NSAIDS,
anticonvulsants, analgesics
3. Morphology of a drug eruption: exanthematous=> hypersensitivity syndrome;
urticarial=>serum sickness (like) reaction, anaphylaxis; vesiculobullous=>
steven Johnson syndrome/ TEN; Pustular => acute generalized examthematous
pustulsis
4. drug ... 阅读全帖 |
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p**********r 发帖数: 108 | 40 ☆─────────────────────────────────────☆
pray2008 (stock888) 于 (Sun Apr 11 22:47:41 2010, 美东) 提到:
http://gwestrookitraders.com/fdadates.html
☆─────────────────────────────────────☆
tanmaomao (坛猫猫) 于 (Mon Apr 12 10:03:52 2010, 美东) 提到:
Biotech Stocks Facing FDA Approval From April - October 2010
Cell Therapeutics (CTIC)
Drug/indication: Pixantrone for non-Hod1gkin's lymphoma
Approval decision date: April 23
An FDA advisory panel held on March 22 voted 9-0 to recommend against
approval of ... 阅读全帖 |
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c****n 发帖数: 21367 | 41 这句话有个屁用,除了捞funding和骗老百姓
转基因的实验数据才多点儿啊?才多少时间啊?
别说什么“这是我们能做到的最好了”,科学结论是要跟整个样本空间比的
那些生物实验数据合在一起,置信度有万分之一吗?
就是药物那么“严格”的测试,NSAIDs和阿司匹林的冲突是多少年后才发现的?
死了多少人才发现的?
这里很多人都是靠写paper过日子的,这些行话套话都不陌生,
靠这个赚钱吃饭,大家都理解,但是BBS灌个水还想洗脑就没意思了 |
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j*****p 发帖数: 24000 | 42 Ankylosing spondylitis 为什么一开始就要用Infliximab
不先试试NSAID |
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l*****r 发帖数: 687 | 44 布洛芬(英语:Ibuprofen,商品名:芬必得),是一种非甾体抗炎药(NSAID),用来
止痛,退烧和消炎[4]。可用于治疗经痛、偏头痛,和类风湿性关节炎[4] |
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z*****g 发帖数: 75 | 45 baclofen加naproxen,baclofen要处方,先吃naproxen,阿司匹林也管用,nsaid随便
吃点也行 |
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发帖数: 1 | 46 一个都没有
明天睡醒再看吧
: baclofen加naproxen,baclofen要处方,先吃naproxen,阿司匹林也管用,
nsaid随便
: 吃点也行
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z*****g 发帖数: 75 | 47 没事吃点nsaid靠自愈,有事的话运动损伤康复,单单是营养就是一个专业。国内团队
项目不行很大原因就是康复营养专业跟不上。个人项目靠人多,废了一个再上一个,团
队项目哪有那么多人可换。 |
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发帖数: 1 | 48 1月27日对新冠肺炎死亡患者的病理解剖发现,死者的肺部表现为弥漫性肺泡损伤和肺
透明膜形成,符合ARDS表现,总体病理学表现与SARS和MERS相似。流式细胞术可发现淋
巴细胞减少,但淋巴细胞同时也被过度激活。此外,高度促炎性的CCR4+ CCR6+ Th17细
胞增加,导致肺部严重的免疫损伤。
一般抗炎症药物NSAIDs如塞来昔布,特异抗炎症药物,如使用针对Th17细胞激活的IL-
17抑制剂苏金单抗(Secukinumab)可能对缓解病情有用。
慎用糖皮质激素,可引发股骨头坏死(在非典治疗中,北京登记在案的有300名患者,
因在非典治疗中大量使用糖皮质激素而从此丧失劳动能力)。 |
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发帖数: 1 | 49 【明報專訊】本月中,法國衛生部警誡,有新型冠狀病毒肺炎徵狀人士勿自行服用布洛
芬(ibuprofen),恐加重病情。世界衛生組織(WHO)隨即建議有相關徵狀人士避免服
用布洛芬;但不久又推翻建議,表示「不建議反對使用布洛芬」。與此同時,醫學期刊
《刺血針》文章指出,布洛芬可能導致新冠肺炎病情惡化。
布洛芬是消炎止痛藥常見成分,在香港雖屬監管藥物,但不少港人遊日本、歐美時購買
當地的複方感冒藥或止痛藥,都含有布洛芬。各方專家意見分歧,背後有何理據?是否
需要停止服用布洛芬?
布洛芬屬非類固醇消炎藥(NSAIDs),適用於輕度至中度疼痛,具退燒、止痛、消炎作
用,在外國較撲熱息痛更被廣泛使用。新型冠狀病毒肺炎在全球爆發後,很多確詡付
荚貌悸宸遥洞萄槨方湛俏恼拢覆悸宸一驅е滦鹿诓∏閻夯O愀坩t
院藥劑師學會會長崔俊明解釋,布洛芬藥理作用是抑制前列腺素製造,令血液減少流到
腎臟,腎臟的調控機制便會使身體細胞表面的ACE2(血管緊張素轉化酶2)增加。「
ACE2就像是門,多開幾道門,病毒就更容易進入。」由於新冠病毒透過ACE2進入人體的
細胞,因此有推論指布洛芬會加重病情。 |
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h******o 发帖数: 976 | 50
药总是不得已吃吃的,像tylenol这种药有损肝的副作用,而ADVIL算NSAIDs类的止痛药
,对胃肠道也照样有影响。只是友情忠告,我也是不得已才吃。能忍则忍呗 |
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