c********1
发帖数: 35 | 1 第2个好像不太对啊。这样PTO expense就overstate啦。。 |
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s*******u
发帖数: 28 | 2 f I were you, I would definitely go to GSU even without financial support
because you may get more chances in job hunting from their job career
～～～～～～～～～～～～～～～～～～～～～～～～～～～～～～～～
This is way more overstated
service. And there are 3 Chinese students getting full-time positions in GSU
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
AIG coming to recruit is a real small probability event
over the last couple of years |
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m******5
发帖数: 1383 | 3 手头一篇BBRC 肯定overqualify，但JBC又有点悬的文章在写
有很多想法想写在introduction和discussion里，但又比较担心：reviewer会不会反而
反感这种overstate自己工作意义的写法？（藏得再聪明reviewer都看得出来吧……） |
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k****a
发帖数: 7077 | 4 没有强迫，没用，只是询问下。你不要overstate。 |
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d*****r
发帖数: 2583 | 6 man, the reason is very simple:
1. every lab needs to get money to survive.
2. to get money you need high profile papers.
3. to get high profile papers you need solve big problems
4. most people most of the time cannot solve big problems, to keep
publishing CNS, they have to over-state their findings and data
5. if everyone else in the field over-state their findings and data,
then you have to overstate too, unless 1), you are big enough you don't
care, or 2), you want to be wiped out of this fi... 阅读全帖 |
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y******8
发帖数: 1764 | 7 No only for hematopoietic system. Basically, you can screen for any
phenotype, but use soluble molecules instead of genetic methods. By this way
, you would directly get drug candidates, not just drug target candidates.
The transparency of fish embryo is overstated. If you want deal with any
late-onset disease, the adult fish is not very transparent. |
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n***3
发帖数: 663 | 8 其实董晨这个人是相当聪明的，方向从Th17逐渐转到Tfh也是大势所需，毕竟Th17已经
火了一个decade了，重大的发现不太容易再轻易得到了。
其实免疫领域真正从能从basic concept角度做出 groud breaking work的人不多，大
多数现在所谓的牛人好多是照搬原来的idea, 随便搞个什么transcription factor, 然
后direct T xx cell differentiation and function, 再搞掂cytokine的story, 自己
建个mouse model玩的不亦乐乎。这种paper在CNS, Nature Immunology上面比比皆是。
我个人觉得现在大家都在猛追新发现，好多已经发现的东西研究的不够深，而且更大的
问题是，大家的成果都相对独立，各自make story, 各自建mouse model, 然后证明自
己的理论正确。没有人把这些东西整合一下，所以临床的实际应用价值很差劲。当然了
，这种整合的工作风险很大，很可能最后什么都弄不出来，很大原因是因为原来的已有
的paper 都倾向于overstate自己研... 阅读全帖 |
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p********e
发帖数: 609 | 9 Went through it quickly so don't quote on my comments.
The title is certainly overstated. There are many cavities in this work, to
name a few:
1) CCI -> mTOR inhibition >> autophagy: may or may not related with
autophagy.
2) CCI suppresses necrosis?: not well-defined.
3) Is downregulation of RIP3 a cause or consequence of attenuated cell death
? Not answered.
4) How does CCI regulate the RIP1/RIP3 levels?
... Plus, the quality of the data is not that great.
Just my 2 cents. |
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j*****p
发帖数: 8 | 10 刚投了一篇，折腾了半年最后悲剧了。
第一轮（花了2个半月时间。。。）：
Reviewer #1: Good,补一些实验
Reviewer #2: Good,补一些小实验，去一些不必要的数据。
Reviewer #3: Good,要求补的实验和reviewer #1差不多。
Reviewer #4：This is too preliminary and bullshit, overstate their results
everywhere...从提的问题大概猜到是领域内的一个大牛（可能在做类似的工作），没
有对hypothesis和conclusion提具体问题，就要求用一些不public available的tools
做实验。
给了两个月时间修改，补了#1,2,3所有要求的实验和一部分#4要求的实验，讨论了#4其
它的问题。两个月后送回。
第二轮（又花了1个半月时间。。。）：
Reviewer #1: 没问题了，Accept
Reviewer #4：Still bullshit!
Editor: Reject.
老板气坏了，给Editor board写信，质疑#4可能从事同样的工作... 阅读全帖 |
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j*****p
发帖数: 8 | 11 刚投了一篇，折腾了半年最后悲剧了。
第一轮（花了2个半月时间。。。）：
Reviewer #1: Good,补一些实验
Reviewer #2: Good,补一些小实验，去一些不必要的数据。
Reviewer #3: Good,要求补的实验和reviewer #1差不多。
Reviewer #4：This is too preliminary and bullshit, overstate their results
everywhere...从提的问题大概猜到是领域内的一个大牛（可能在做类似的工作），没
有对hypothesis和conclusion提具体问题，就要求用一些不public available的tools
做实验。
给了两个月时间修改，补了#1,2,3所有要求的实验和一部分#4要求的实验，讨论了#4其
它的问题。两个月后送回。
第二轮（又花了1个半月时间。。。）：
Reviewer #1: 没问题了，Accept
Reviewer #4：Still bullshit!
Editor: Reject.
老板气坏了，给Editor board写信，质疑#4可能从事同样的工作... 阅读全帖 |
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a********h
发帖数: 245 | 12 The sad and sobering tale of how allegedly fabricated results of research
led by a Johns Hopkins University lab led to the suicide of a scientist in
Taiwan,and the dismissal of the man who blew the whistle, are the focus of a
feature in yesterday's Washington Post.
The story is the tale of Daniel Yuan, formerly a genetics researcher in Jeff
Boeke's lab at Hopkins. For years, Yuan suggested that data being generated
in the lab's studies of gene interactions in yeast were suspicious.
Yuan was dism... 阅读全帖 |
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a********h
发帖数: 245 | 13 The sad and sobering tale of how allegedly fabricated results of research
led by a Johns Hopkins University lab led to the suicide of a scientist in
Taiwan,and the dismissal of the man who blew the whistle, are the focus of a
feature in yesterday's Washington Post.
The story is the tale of Daniel Yuan, formerly a genetics researcher in Jeff
Boeke's lab at Hopkins. For years, Yuan suggested that data being generated
in the lab's studies of gene interactions in yeast were suspicious.
Yuan was dism... 阅读全帖 |
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g******4
发帖数: 6339 | 14 【 以下文字转载自 Parenting 讨论区 】
发信人: gogo2004 (挑灯看剑), 信区: Parenting
标 题: 小孩家长必看::[视频] 上百万只蜜蜂离奇死亡，咋回事？ (转载)
发信站: BBS 未名空间站 (Mon Jan 13 22:47:33 2014, 美东)
--------------
看来，首先不能让小孩吃蜂蜜
==========================
Pesticides
Further information: Pesticide toxicity to bees, Imidacloprid effects on bee
population, and Bees and toxic chemicals
According to the U.S. Department of Agriculture, pesticides may be
contributing to CCD.[49] Scientists have long been concerned that pesticides
and possibly some fungi... 阅读全帖 |
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c*******r
发帖数: 54 | 15 Recent US government budgets have harmed the National Institutes of Health.
But the problems in the medical research system are deeper than just the
current budget. If you care about medical research, read this article in the
Proceedings of the National Academy of Sciences by Bruce Alberts, Marc
Kirschner, Shirley Tilghman, and Harold Varmus.
Alberts and his colleagues describe a hypercompetitive culture in science
that undermines the process of discovery.
Competition… has always been a part... 阅读全帖 |
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O******e
发帖数: 4845 | 16 我推荐大家都读一下这篇文章：
http://www.pnas.org/content/111/16/5773.full
全文：
By Bruce Alberts, Marc W. Kirschner, Shirley Tilghman, and Harold Varmus
By many measures, the biological and medical sciences are in a golden age.
That fact, which we celebrate, makes it all the more difficult to
acknowledge that the current system contains systemic flaws that are
threatening its future. A central flaw is the long-held assumption that the
enterprise will constantly expand. As a result, there is now a severe
imbalan... 阅读全帖 |
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m*********D
发帖数: 1727 | 17 Disputed Research Ends in Tragedy
A biomedical researcher whose Nature paper was called into question was
found dead in his lab.
By Dan Cossins | March 14, 2013
4 CommentsPrint
Link thisStumbleTweet this
FLICKR, PLAXCO LAB
A Taiwanese biomedical researcher who co-authored a Nature paper while at
Johns Hopkins University (JHU) may have killed himself last summer, on the
day he was due to submit a written response to questions regarding the study
's conclusions, reported The Washington Post.
The s... 阅读全帖 |
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i*********0
发帖数: 915 | 18 reviewer发话了，说我们文章的用词太过strong，有的时候有点overstate。
我想问问大家，suggest，indicate，imply，等等这写词，那个意味强一点？
谢谢！ |
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d*****n
发帖数: 166 | 19 persistence is somewhat overstated, especially in our culture. The reality
is the one who can adapt and ride the trend will survive. Change, before it
is too late. |
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O********4
发帖数: 113 | 20 是真偷了有用的东西，还是杀一儆百？
Two GlaxoSmithKline scientists and three others were charged by a federal
grand jury in Philadelphia on Wednesday with conspiracy to steal promising
cancer research secrets from the pharmaceutical giant and market them to
companies in China backed by the Chinese government.
U.S. Attorney Zane David Memeger said Yu Xue, 45, of Wayne; Tao Li, 42, and
Yan Mei, 36, both of Nanjing China; Tian Xue, 45, of Charlotte, N.C.; and
Lucy Xi, 38, of West Lake Village, Calif., were named in ... 阅读全帖 |
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OE
发帖数: 369 | 21 compared with par bond, discount bond has lower coupon rate ---> lower
coupon payment ---> all coupon payment is in CFO as interest expense --->
overstate CFO.
in this case, coupon payment = the interest expense in income statement (
this is accurate interest expense) - amortized discount |
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J**********y
发帖数: 1891 | 22 老是搞不明白。
还请大家指点一下。
非常感谢。 |
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h**********k
发帖数: 168 | 24 There are several categories or types of potential bias in using changes in
the CPI as a measure of the change in the cost of living. 1) Substitution
bias occurs because a fixed market basket fails to reflect the fact that
consumers substitute relatively less for more expensive goods when relative
prices change. 2) Outlet substitution bias occurs when shifts to lower price
outlets are not properly handled. 3) Quality change bias occurs when
improvements in the quality of products, such as greate |
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e****c
发帖数: 183 | 25 I don't know much about the topic, but this seems to be overstating the case
. According to the following link, at least Kenneth Arrow, Robert Solow, Joe
Stiglitz, Clive Granger, and Lawrence Klein support it.
http://www.epi.org/content.cfm/minwagestmt2004 |
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s*h
发帖数: 1538 | 26 Last year I reviewed 500 applications from applicants who graduated outside
of the US.
Did I read 500 personal statements? No. Did I screen in anyone based on
their personal statement alone? No. How many did I personally read? I only
read the ones of the candidates that we interviewed. How many were really
read closely? Only the ones who we discussed ranking for residency.
What is the personal statement for?
When I interview you, I want to know where you came from, what you have done
and what yo... 阅读全帖 |
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c****e
发帖数: 2097 | 27 You don't know Bryce DeWitt? Did you not read the very first serious
papers on canonical quantization of gravity? I thought those were
the 3 papers by DeWitt :D I guess you meant not to put those 2
brighter guys with Lee Smolin.
Lubos is probably right on many things, but apparently there's 1 LQG
speaker in strings this year. I just like to use my own judgement
instead of others, however it's hard to have time to go into that
literature, as it's pretty unenlightened.
I don't want to overstate it |
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s********a
发帖数: 1100 | 28 某些vairable在某段时间内有预测能力的
你是不是variable 就选的不对 overstate it的能力了。。 |
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l****d
发帖数: 55 | 29 OK,apologies for what I said。Here is what I think. Louzhu is seriously
seeking some information here. From the questions you asked (including the
questions here and your gf's pregnancy), my feeling is that you read a lot,
think a lot and might understand something deeply. But you are a bit geeky
in asking the pregnancy question online. Dude, please don't take it as
insulting but the first thing I would do if I find my gf is pregnant is to
go ask a doctor, not post questions on bbs. You should re... 阅读全帖 |
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J*****n
发帖数: 4859 | 30
No, it is kind of dangerous. U can overstate, but can't lie. |
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J*****n
发帖数: 4859 | 31
No, it is kind of dangerous. U can overstate, but can't lie. |
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u******3
发帖数: 11 | 32 one depedent variable, several independent variables. and so I develop a
regression model for them. the problem is that among several independent
variables, they might be correlated. Hence, I think it necessay to isolate
the effect of correlation or I will overstate the impact of these
independent variables on the dependent variable. What is the statistical
tool to isolate or test the correlation among indepedent variables? Sorry
but statistics is not really my area. |
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j**********e
发帖数: 367 | 33 一个病没及时诊断， 瞎了过一辈子， 瘫痪了坐一辈子轮椅，运气不好的得等下辈子轮
回了，
1. Are you sure about what you said?
2. It seems to me that you are overstating or over-exaggerating the power of
doctors. are you saying that doctors are GOD Jesus Christ, Ru Lai Fo, or Yu
Huang Da Di, or even Sun Wu Kong?? |
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l*****9
发帖数: 9501 | 34 http://www.examiner.com/article/despite-obamacare-rollout-progr
Despite Obamacare rollout, Progressives see single-payer health care as goal
December 10, 2013
Among the people who express dissatisfaction with Obamacare (the Affordable
Care Act), the bigger number are actually progressives who were upset by the
contortions Obama went through to preserve profit-making private insurance
companies as the gatekeepers to the health care system.
Progressives wanted a single-payer system which every o... 阅读全帖 |
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m***i
发帖数: 2013 | 35 overstated conclusion
要是每个睡眠障碍后面都是神经退行，那得有多少人从多年轻就开始了。这样的话，我
也得担心自己了，至少我的睡眠经常有问题，更不要说我认识的很多人因为精神压力大
或者其他原因而会经常整夜失眠的 |
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c*m
发帖数: 836 | 36 我家一辆前轮的，一辆后轮的，我经常换着开。说实话，除了下雪，没觉得有啥区别。
要说每天都能感到的最大的区别，就是因为后轮驱动的车的differential占了很大空间
，导致trunk比fwd的浅了不少。其实两种车所谓的区别，什么under steer over steer
的，严格意义上讲，都是失控情况下的特性。如果你从来不把车push到失控的边缘，恐
怕很难觉出来区别。
如果是在赛道上，随时都在失控的边缘，就是另一回事了，fwd最大的弱点就在于驱动
和转向在同一组轮胎上，所以可用的traction要在这两个方面分配，还有就是万一前轮
打滑除了减速和steer into the skid之外什么也不能做。而rwd的车，driver对四个轮
子都有控制。
fwd的重量集中在前面，对赛车很不利，但是雪天优势就大了，呵呵。
fwd还有torque steer的缺点，不过这个很容易克服，用一样长的drive shaft就可以了。
fwd会under steer, rwd倾向于oversteer, 但是这个不是绝对的，跟你怎么入弯和前后
suspension怎么配很有关系，把fwd改成倾向于o |
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B*******S
发帖数: 2379 | 37 新加sway跑了十天有余, rear从起初最软放到了中间的位置.
车转弯倾泻减少了, 过去40的弯现在45, 急转弯时松开油门会明显感到车开始
oversteer, 就指望轮胎能扒的住地了
Engine bay很脏, 周末调了调coilover, 降了降高度, 弹簧调到最硬 |
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b***i
发帖数: 10018 | 38 你用什么车? pp500 or pp750?
把physics调到professional后，开大马力的车power oversteer比较严重，的确很真实 |
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x*****n
发帖数: 3422 | 39 LFS, single player -> autocross map -> skidpad, choose car FZR
rear engine, rear drive, F:R ratio 36:64, 基本上就是加了turbo的911
很容易就lift-off oversteering. 建议按F键打开force vector显示模式 |
|
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F*********e
发帖数: 2696 | 41 刹车打方向，我在雪地上oversteer过
小下坡的右弯，挺缓的，但是我速度太快
开始下坡的时候已经开始感觉速度太快，带上刹车了，开始入弯的时候感觉还是有点un
der，于是脚下刹车重一点，再然后就剧烈over了，没机会反打方向，直接180度调头撞
进路边的雪堆，后来AAA来救我的
不过有ABS比没有是会好很多
某天我在local开着莫名其妙就ABS系统警告灯亮，不是ABS启动的那个灯，是警告ABS不
工作的那个灯，以前有过两次，都是刚启动就警告，熄火再打火就没事的。。。正好前
面有个加油站我就想进去重新启动一下，结果就那一小段路有压得很硬的积雪，一刹车
就扭了两下，还好速度不快，我方向救得及时，没出什么事。就那么一次在路上ABS不工
作，后来就没有过，当时就紧张得厉害 |
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F*********e
发帖数: 2696 | 42 先从小马力的开始
过弯的时候需要全身用力抵抗离心力，很消耗体力的
一般刹车是在后轴上的，刹车和方向盘同时动作的话很容易oversteer
后轴没有差速器，所以油门放得不够的话容易understeer |
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b***i
发帖数: 10018 | 43 FWD重量分配不如RWD完美，操控就会受到影响
还有understeer/oversteer这些不用push到limit都可以体现出来
再说，road car的limit也不是很高的，起码我自己的车很容易push到limit |
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c*********r
发帖数: 19468 | 44 but torsen c quattros can do power oversteering too (thanks to its 40:60
power split ratio)
and if you can get a B8 S4 with quattro torque vectoring, that'll be even
easier (and safer) |
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x*****n
发帖数: 3422 | 45 generally speaking, no.
除了拉力赛，其他比赛很少看到那么夸张的drift，实践说明问题。
其实漂移没啥神秘的，当车接近极限的时候，都是处于飘和不飘的临界状态。再怎么调教的赛车，也不可能在每个弯都是完全neutral的。怎么合理计划/分配/利用oversteering/understeering就是个million dollar question了。
想起来某些老外车坛的月经贴，drift到底是不是racing。有个比方很好，drift是figure skating，其他比赛是speed skating。你说它是它就是，你说不是就不是。 |
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x*****n
发帖数: 3422 | 46 玩LFS的时候，唯一能明显感受lift oversteer的车，就是那辆r/r的伪911 |
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y*******n
发帖数: 10103 | 47 还有那辆敞篷的MR车，超级oversteer。 |
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x*****n
发帖数: 3422 | 48 我瞎说几个，你随便听听：
1。look ahead，这个说起来容易做起来难，据说至少要提前两个session。我最多也就
瞄瞄下一个session，还经常盯着apex不放，呵呵。这直接导致我走线不够好。
2。throttle control。我去年前半段过slalom的时候基本constant throttle，速度不
够踩深点，速度过了踩浅点。后来才意识到可以通过throttle控制车的oversteering/
understeering倾向，配合方向盘的节奏踩油门。其实course的绝大部分都能这么干，
比如clamshells。我现在还是处于东施效颦阶段，力度拿捏/时机都和高手有差距。
3。downshift，autocross降一档的机会不多，不过一旦有这种180度变态慢pivot，
downshift好不好能差半秒。很多了。
4。尽早push to the limit。我这人比较ws，经常到了下午的session才真正找到limit
，调整都来不及了，最后成绩总比理想的要差~1秒
5。硬件trick, 每个class总是有些trick的。比如stock class：brak |
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a*********g
发帖数: 2853 | 49 Elise比S2000轻，低速应该有优势，弯道也应该占优。不过马力不够，高速的时候就吃
亏了。Elise还有个问题就是屁股太重(38F62R，跟Carrera一样了)，容易oversteer |
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s******y
发帖数: 431 | 50 S2000如果把VSA关了也容易OVERSTEERING啊。。还是技术最重要 |
|
