b**s
发帖数: 589 | 1 1。
A photolabile hydrogel for guided three-dimensional cell growth and migration
Y. LUO AND M. S. SHOICHET
Nature Materials 3, 249; April 2004.
| Abstract | Full Text (HTML/PDF) |
Tissue engineering sees the light
To replace or repair body tissues from cultured cells requires a 'scaffold'
that contains pathways to support and guide cell organization. Such
biochemical channels have already been created in two-dimensional gel matrices
to guide tissue formation. But in this month's Nature Materials |
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b**s
发帖数: 589 | 2 在丁香园转了半天，发现在国内赚点小钱也很容易
象这样的公司听说都发了
http://www.fstysw.com/Ins_cpjj.htm#
我可以在那里贴个广告，专门卖我的scaffold，我的最大优势是
可以实现生长因子在三维的可控分布，而且可以controlled release
用公司的机器偷偷做，材料自己买
大家认为如何？ |
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c*s
发帖数: 2145 | 3 来自主题: Macromolecules版 - 今天的收获 just curious, how to realize "利用scaffold在三维释放出不同区域的growth factor,
signaling molecules"
sounds to me you guys can control the orientation of cell growth at will.
or change to another way: you cna control the 3-D spatial position at cell
level.
this sounds too aggresive
个
物
趾
办
成
少
)
它 |
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b**s
发帖数: 589 | 4 来自主题: Macromolecules版 - 今天的收获 If you have 5-dimentional (X,Y,Z,Compositional,Time-elapse) capability, you
can do it. Imagine a 3-D color printer using a drug controlled release ink.
factor,
一
动
个
种
化
取
cell，然后在放在scaffold里(当然要我们的heterogenerous的
使 |
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w********h
发帖数: 12367 | 5 来自主题: Macromolecules版 - 今天的收获 I am also surprised by argon's poor English. hoho...
cashine's English is quite good.
assume
"利用scaffold在三维释放出不同区域的growth
at
兼 |
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c***r
发帖数: 3965 | 6 来自主题: Macromolecules版 - 今天的收获 非也非也,在有路的情况下,轮子确实比腿有效率.
所以如果能让人进化出轮子,以后大家就不用买车了.
一
动
个
种
化
取
cell，然后在放在scaffold里(当然要我们的heterogenerous的
使 |
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w********h
发帖数: 12367 | 7 next time, get me a scaffold using my polymer,
I will put your name as second-author...hoho |
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b**s
发帖数: 589 | 8 I know a little bit of him
He is the guy who use polypeptide to make tissue engineering scaffold
The funny thing is that: the work published in Nature or Science normally
means that it will take more than 20 years to 技术转化. I would rather to
invest on projects which can make money in 5 years.
全
麻
科
部
求
工
建
新
川
究
独
大
研究计划等），同时争取获得国内外企业的重要科研资助，获准科研经费要达到约3000万
高
获
制
运
设
管
学
15
并
司
研
批
的 |
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p******e
发帖数: 164 | 9 来自主题: Macromolecules版 - 请教 stereolithography...
injectable biomaterials for scaffold fabrcation |
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y****o
发帖数: 50 | 10 好文章，DSC不错。提个笨笨的问题，porosity和pore size是一回事吗？有的文章用
blotted dry method去测porosity因为材料的密度一致，但是要是不知道密度（比如说
混合材料），那这种方法的可行性如何？--〉Controlling the porosity of fibrous
scaffolds by modulating the fiber diameter and packing density有什么更好的方
法（如果不用diffusion,因为材料的限制-fragile &thin）？
另外有的方法用algorithm预测pore size,可能使我背景差，没太看懂怎么算的555
Eichhorn SJ, Sampson WW. Statistical geometry of pores and statistics of
porous nanofibrous assemblies. Journal of the Royal Society, Interface / the
Royal Society 2005;2(4):309-18.
非常感... 阅读全帖 |
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x*****g
发帖数: 82 | 11 国内有机硕士毕业，博士期间的工作经历如下
Synthesis and characterization of Polymer & monomer, Modification functional
molecules to polymer scaffolds
The application of synthetic biocompatible polymers, like drug and gene
delivery
Operating Instrumentals, NMR, HPLC, GPC, MS (MALDI-TOF),TEM, Confocals IR,
DLS etc.
publication现在只有一篇jacs和国内时候发的几篇有机方向文章，还有4-5篇已经投出
或者即将投出。
明年五月份毕业，不知道能不能在毕业前找到位子。
将来何去何从还没有打算。
请大家给点建议，现在心里很忐忑，谢谢 |
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u*****e
发帖数: 357 | 12 Need dissertation copy: PROQUEST
Reinventing fibrin: Development of angiogenic tissue engineered scaffolding
Please email me at w****[email protected]
Thanks a lot. |
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w********h
发帖数: 12367 | 13 Lab-made organ implanted for first time
By Madison Park, CNNJuly 8, 2011 9:32 a.m. EDT
Scientists created an artificial trachea using polymers that had a spongy
and flexible texture.
In June, doctors implanted an artificial trachea into a 36-year-old man
The organ was created in a lab and bathed with the patient's stem cells
It took away the need for the patient to wait for a donor organ
(CNN) -- For the first time, a patient has received a synthetic windpipe
that was created in a lab with the p... 阅读全帖 |
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t****t
发帖数: 45 | 14 Job Title: Postdoctoral Position in Biomaterials, Stem Cells, and Tissue
Regeneration
Application Deadline: Open Until Filled
Job Description
Description:
The Department of Biomedical Engineering at the University of Minnesota
currently has an opening for a post-doctoral fellow to conduct studies in
the area of biomaterials and tissue regeneration. The project involves
materials engineering on the molecular level, scaffold fabrication, and stem
cells.
Qualifications:
Candidates must have a Ph.D.... 阅读全帖 |
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w********h
发帖数: 12367 | 15 赞"一个踏实工作的研究者，比如我吧"
那个工作没啥好质疑的,
不过是有些人比较愚昧,以为不用scaffold就能长个人耳而已.
你若是做tissue engineering的,
没听过曹谊林,有点不够广闻.
当年和Vacanti的工作,还是很吸引眼球的.
当然,所有的科研工作者都应该用正面的态度对待质疑,
只是,这质疑来的真是时候,估计科学的成分很少了吧. |
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s***q
发帖数: 3 | 16 PhD position on biomaterials and Tissue Engineering
The Biomaterials research group at Florida Atlantic University (FAU) would
like to invite applications for a 3-4 year PhD position starting 2015 full
semester.
Project Description
The biomaterials lab at the Department of Ocean and Mechanical Engineering
at FAU is looking for a PhD student in the area of biomaterials for tissue
engineering and regenerative medicine.
Biomaterials including bioceramics and polymers have been extensively
applied i... 阅读全帖 |
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P******e
发帖数: 344 | 17 Biomaterial, tissue engineering, scaffold design,
Protein fiber, silk, regenerative medicine, electrospining, ect.
Thanks. |
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l******g
发帖数: 278 | 18 A 32-year-old construction worker is brought to the emergency department
20 minutes after falling 18 feet from a scaffold. He was immobilized at the
scene and placed on a backboard for transport. On arrival, he is moaning
and responds only to painful stimuli. His pulse is 130/min, respirations are
16/min, and blood pressure is 85/40 mm Hg. Examination shows no evidence of
external bleeding. There are ecchymoses over the forehead, left lower chest
, and upper abdomen. He is intubated, and two... 阅读全帖 |
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s***q
发帖数: 3 | 19 PhD position on biomaterials and Tissue Engineering
The Biomaterials research group at Florida Atlantic University (FAU) would
like to invite applications for a 3-4 year PhD position starting 2015 full
semester.
Project Description
The biomaterials lab at the Department of Ocean and Mechanical Engineering
at FAU is looking for a PhD student in the area of biomaterials for tissue
engineering and regenerative medicine.
Biomaterials including bioceramics and polymers have been extensively
applied i... 阅读全帖 |
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f***s
发帖数: 533 | 20 I'm only posting, please do not contact me.
It sounds like for GC holders only. Automation experience is highly desired.
contact the company directly at l**[email protected]
==============================================================
Sr. Associate Scientist, Protein Engineering and Display Technologies
We are seeking a scientist to join our Protein Engineering effort
exploring the use of alternative protein scaffolds in immunology,
oncology and diagnostics.
The successful candidate wi |
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s**********g
发帖数: 413 | 21 亲戚家小孩想找药企的研发，不知道如何提升背景，先行谢过板上的各位大大
目前背景是biomedical engineering PhD, tissue engineering track with polymer
background
Techniques: cell culture (2D, 3D), ex vivo tissue culture. DNA/mRNA
extraction Westernblot, PCR, magpix multiplexing, Immunostaining,
Immunohistochemistry, Fluorescent/confocal microscopies, Flow cytometry,
Hydrogel fabrication, Scaffold mechanical testing (Instron)
research focus: immunology(macrophage activation and roles), stem cell
immunomodulatory effect, osteoarthritis
个人感觉药... 阅读全帖 |
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qk
发帖数: 14 | 22 Tissue Eng. 2006 Jul 1
Collagen-GAG Scaffolds Grafted onto Myocardial Infarcts in a Rat Model: A
Delivery Vehicle for Mesenchymal Stem Cells.
Xiang Z, Liao R, Kelly MS, Spector M.
Department of Orthopaedic Surgery, Huaxi Hospital, Sichuan University,
Chengdu, China., Tissue Engineering, VA Boston Healthcare System, Boston,
Massachusetts., Department of Orthopaedic Surgery, Brigham and Women's
Hospital, Boston, Massachusetts., Harvard Medical School, Boston,
Massachusetts.
MY Email: q**[email protected] |
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qk
发帖数: 14 | 23 Second-Generation Inhibitors for the Metalloprotease Neprilysin Based on
Bicyclic Heteroaromatic Scaffolds: Synthesis, Biological Activity, and X-Ray
Crystal-Structure Analysis
Helvetica Chimica Acta
Volume 88, Issue 4, Date: April 2005, Pages: 731-750
Stefan Sahli, Brian Frank, W. Bernd Schweizer, François Diederich,
Denise Blum-Kaelin, Johannes D. Aebi, Hans-Joachim Böhm, Christian
Oefner, Glenn E. Dale |
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s**********8
发帖数: 25265 | 24 A medical device is a product which is used for medical purposes in patients
, in diagnosis, therapy or surgery[citation needed]. Whereas medicinal
products (also called pharmaceuticals) achieve their principal action by
pharmacological, metabolic or immunological means. Medical devices act by
other means like physical, mechanical, physico-chemical or chemical means.
Medical devices are included in the category: Medical technology.
Medical devices include a wide range of products varying in comp... 阅读全帖 |
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s**********8
发帖数: 25265 | 25 Biocompatibility
From Wikipedia, the free encyclopediaJump to: navigation, search
http://en.wikipedia.org/wiki/Biocompatibility
Biocompatibility is related to the behavior of biomaterials in various
contexts. The term may refer to specific properties of a material without
specifying where or how the material is used (for example, that it elicits
little or no immune response in a given organism, or is able to integrate
with a particular cell type or tissue), or to more empirical clinical
success ... 阅读全帖 |
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b**z
发帖数: 1351 | 26 汉语 http://www.hanbio.net/xueshu/item/123
英文 http://www.nature.com/news/neuroscience-method-man-1.13077
Karl Deisseroth一次又一次地用他发明的新技术在脑科学（brain science）发展
史上刻下了自己的大名。
Karl Deisseroth在2004年有了第一个完全属于他的实验室，后来他发现那间实验
室的前主人竟然是诺贝尔物理学奖得主朱棣文（Steven Chu）。“我搬进实验室的
时候，朱棣文的名字还挂在实验室的门上。”美国加利福尼亚州斯坦福大学（
Stanford University in California）的神经科学家Deisseroth回忆说。沾名人
的光总是有好处的，后来有一位化学系的学生Feng Zhang拜访朱棣文时，
Deisseroth居然用尽花言巧语把他给留了下来，“虽然Zhang没听说过我，可是我
让他对我的课题产生了兴趣。” Deisseroth得意地说道。
Deisseroth现在可是科学界的大牛之一了。有两项意义重大的技术都与
De... 阅读全帖 |
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z*******n
发帖数: 1034 | 27 免费游戏模式束缚着开发者的双手
发布时间：2014-05-22 17:11:19 Tags：付费模式,免费游戏,市场,手机平台,玩家
作者：Barry Meade
在今年的三月初，Fireproof公开了一个好消息，即自从我们的手机游戏《The Room》
和《The Room 2》发行以来已经卖出了550万份了。
在Fireproof，我们总是能听到一款手机游戏必须是休闲的，且能够免费下载的说法，
作为一种服务的游戏将永久地出现在玩家面前。但因为我们的游戏都很短，既黑暗又残
忍，不存在社交或在线元素，且不包含应用内部购买或广告，所以这便是一大问题。
the room(from d.cn)
the room(from d.cn)
我们同样也缺少足够的钱去支付专业的市场营销或PR。但是依靠着苹果的App Store的
推荐，我们这款基于7万英镑预算的游戏获得了超乎预期的成功。
在对于我们所获得的成绩的评价时，我发了一条tweet表示，也许手机游戏在免费玩家
之间的盈利战导致开发社区更加依赖于“数据之谈”，同时渐渐忽视了一款优秀的游戏
会对玩家产生怎样的影响。关于开发者一味地追求娱乐而不是... 阅读全帖 |
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w*******y
发帖数: 60932 | 29 Werner MT-13 300-Pound Duty Rating Telescoping Multi-Ladder, 13-Foot:
http://www.amazon.com/Werner-MT-13-300-Pound-Telescoping-Multi-
Technical Details
13-foot telescoping multiladder with 300-pound duty rating
13 different working heights or positions by converting into a 2-person
stepladder, extension ladder, or scaffold
The soft touch push knobs are the key to this versatile ladder enabling
you to get the job done easier with this versatile ladder
This professional grade ladde... 阅读全帖 |
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w*******y
发帖数: 60932 | 30 Link:
http://www.lowes.com/pd_78390-287-MT-13_0__?storeId=10151&Ntt=m
Technical Details
13-foot telescoping multiladder with 300-pound duty rating
13 different working heights or positions by converting into a 2-person
stepladder, extension ladder, or scaffold
The soft touch push knobs are the key to this versatile ladder enabling you
to get the job done easier with this versatile ladder
This professional grade ladder is built to last with double-riveted steps
with a more durable design than oth... 阅读全帖 |
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w*******y
发帖数: 60932 | 31 Rat On A Scooter XL Link:
http://itunes.apple.com/app/rat-on-a-scooter-xl/id342699962?mt=
We are giving away THREE awesome DONUT GAMES for free during a limited time:
- Rat On A Scooter XL
- Chicken & Egg
- Lucky Coins
Search the AppStore for "Donut Games"
Grab em' all, and TELL YOUR FRIENDS TO HURRY while they're FREE.
- - - - - - - - - - - - - - - - - -
WARNING! Considered one of the most addictive games on the App Store... if
you start playing you may have a hard time to stop.
*** #1 Download... 阅读全帖 |
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c*******k
发帖数: 1437 | 34 这个老师的general 出发点是好的。但是可能不太适合中国家长和中国孩子的情况。她
by default assume中国家长的这种push行为是会给小孩造成压力，让他们早早失去兴
趣，从而在将来的学习生涯中没有真正的学习的快乐和动力，而是为了单纯地please家
长。问题是也许这种push对很多美国孩子来说会造成她说的那种结果，但对中国孩子也
许不一定。 这个妈妈明明说了自己的孩子就是喜欢阅读和写作，这种情况下家长的Pus
h是适时适当的scaffolding,在成长和学习过程中是很重要的外界力量，也是成人能发挥
的重要作用之一。如果这个孩子的水平早就已经超过了在学校描字母的水平，为什么不
能feed a little bit more呢？ 我记得很小的时候偶尔一次画了一张画不错，然后大人
们就常常夸我有画画的天赋，于是后来我自觉不自觉地就在画画上花了不少时间。没觉
得是为了Please别人，相反是一种自我肯定，成为学画的一个小小动力。总之，什么教
育的原则都应该因人而异的，这个老师的根本出发点还是怕过早push会伤害孩子的学习
兴趣和动力，如果家长的push不仅不会伤害反而有助于... 阅读全帖 |
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