l*****7
发帖数: 8463 | 1 A soda a day could be making your skin look older, new research finds.
Moodboard/Corbis You might want to rethink that soda.
Related
Spot the Warning Signs of Suicide
Tickle Me Pink: Fun Facts About Tickling
More in HEALTHY LIVING
Key Takeaways
Sugar can lead to wrinkles, acne, or a psoriasis flare-up.
For a healthy alternative to soda, add fresh fruit to water.
Always read food and drink labels carefully; if an ingredient ends in “ose,
” that’s a good sign it’s sugar.
Wednesday, October 22, 201... 阅读全帖 |
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p*****c
发帖数: 20445 | 2 A-D E-K L-P R-Z
Peter Baumann, Ph.D.
HHMI Early Career Scientist
Stowers Institute for Medical Research
Peter Baumann’s research focuses on beginnings and endings: beginnings in
the form of reproduction in unisexual lizards and endings in the form of the
telomeres that protect chromosome tips.
Each time chromosomes are copied, telomeres—specialized stretches of DNA
that extend from the ends of each chromosome—become progressively shorter.
With each cell division, they ero... 阅读全帖 |
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j******n
发帖数: 21641 | 3 说到一方水土养一方人，看到一段争论，笑死了
您的位置： 文学城 » 新闻 » 焦点新闻 » 赵薇见照片自叹不像自己
网友：以为是高圆圆(图)
赵薇见照片自叹不像自己 网友：以为是高圆圆(图)
文章来源: 太阳报 于 2014-01-18 10:47:58 - 新闻取自各大新闻媒体，新闻内容并不
代表本网立场！
打印本新闻 (被阅读 26697 次)
赵薇一向以眼睛大获赞，男演员王森有幸同赵薇合照，更分享了自己的喜悦。他说：“
女神，等了一年才等到这迟来的合影﹗”赵薇即回应王森：“怎么不太像我。”不止女
神赵薇觉得合照影得不像自己，网友都纷纷回应“一看以为是高圆圆”、“两人的五官
都挺像”﹗
赵薇与高圆圆（资料图）
赵薇一向以眼睛大获赞，男演员王森有幸同赵薇合照，更分享了自己的喜悦。他说：“
女神，等了一年才等到这迟来的合影﹗”赵薇即回应王森：“怎么不太像我。”不止女
神赵薇觉得合照影得不像自己，网友都纷纷回应“一看以为是高圆圆”、“两人的五官
都挺像”﹗
在线申请最实惠的信用卡 - 12个月开户免息 + 5%现金返还 + 送里程点数换回国机票!
曼康皮肤病... 阅读全帖 |
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s*********a
发帖数: 801 | 4 所有的灵长类都有24对染色体，只有人有23对，为什么？
http://en.wikipedia.org/wiki/Chromosome_2_(human)
All members of Hominidae except humans have 24 pairs of chromosomes. Humans
have only 23 pairs of chromosomes. Human chromosome 2 is widely accepted to
be a result of an end-to-end fusion of two ancestral chromosomes.[3][4]
Fusion of ancestral chromosomes left distinctive remnants of telomeres, and
a vestigial centromereThe evidence for this includes:
The correspondence of chromosome 2 to two ape chromosomes. The close... 阅读全帖 |
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J*****3
发帖数: 4298 | 5 http://en.wikipedia.org/wiki/Chromosome_2_%28human%29
All members of Hominidae except humans have 24 pairs of chromosomes. Humans
have only 23 pairs of chromosomes. Human chromosome 2 is widely accepted to
be a result of an end-to-end fusion of two ancestral chromosomes.[3][4]
Fusion of ancestral chromosomes left distinctive remnants of telomeres, and
a vestigial centromere
The evidence for this includes:
The correspondence of chromosome 2 to two ape chromosomes. The closest
human relative, ... 阅读全帖 |
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w*********r
发帖数: 3382 | 6 关于二号染色体的问题很多，尚无定论
you can let your faith affect your judgment and interpretation of the
evidences, but it is already a fact that chromosome 2 is widely accepted as
the end to end fusion of two chromosomes
理想的证明是在二号染色体上找到两个着丝粒
normally only one centromere can be found in a chromosome, but chromosome 2
has the remaining of a second one. instead of interpreting this as the
evidence of a fusion, you choose to question the deactivation mechanism of
the second centromere. it is good to question, but i... 阅读全帖 |
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h********n
发帖数: 4079 | 7 when you recover telomere, you are immortalizing a cell, so the cell high
much higher chance to become cancer cell. If you can recover telomere of a
whole person, I would guess this person become a big big tumor.
Why? some cell should die after a few passages of division. If they don't
die, the balance will be broken.
so, elongate/recover telomere itself greatly raise cancer risk. |
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m******g
发帖数: 467 | 8 基本上就是题目+bulletin point的形式吧，不要纠结我对paper的品味，呵呵。新年快
乐！
PNAS 13.12.03
推荐：
1. Reintroducing domesticated wild mice to sociality induces adaptive
transgenerational effects on MUP expression
promiscuous / monogamous-line
higher MUP (pheromone) expression in pros-line
Male become more attractive
Difference in Mup promoter methylation level
2. High-throughput DNA sequencing errors are reduced by orders of magnitude
using circle sequencing
Previously ~0.1-1x10^-2
Unique library preparation strategy
Copie... 阅读全帖 |
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m******g
发帖数: 467 | 9 基本上就是题目+bulletin point的形式吧，不要纠结我对paper的品味，呵呵。新年快
乐！
PNAS 13.12.03
推荐：
1. Reintroducing domesticated wild mice to sociality induces adaptive
transgenerational effects on MUP expression
promiscuous / monogamous-line
higher MUP (pheromone) expression in pros-line
Male become more attractive
Difference in Mup promoter methylation level
2. High-throughput DNA sequencing errors are reduced by orders of magnitude
using circle sequencing
Previously ~0.1-1x10^-2
Unique library preparation strategy
Copie... 阅读全帖 |
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k*******t
发帖数: 2113 | 10 dna 就是上帝的编程语言
人类基因与树木基因相同部分，就是基类
dna 螺旋体末端的 Telomere， 就是写代码的缓冲区
Telomere 耗尽之后，就无法复制 DNA了
人就只能等死了 |
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s****e
发帖数: 7018 | 11 细胞分裂的时候，复制基因需要 Telomere 做缓冲。
细胞衰老是因为 Telomere 变短了
无法复制基因了
因此细胞无法更新 |
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n**********1
发帖数: 355 | 12 Crit Rev Eukaryot Gene Expr. 2006;16(2):103-18.
Inside the mammalian telomere interactome: regulation and regulatory
activities of telomeres.
Songyang Z1, Liu D.
Someone can help me with the paper? Thanks!
sent to [email protected]
(function(){try{var s,a,i,j,r,c,l,b=document.getElementsByTagName("script");l=b[b.length-1].previousSibling;a=l.getAttribute('data-cfemail');if(a){s='';r=parseInt(a.substr(0,2),16);for(j=2;a.length-j;j+=2){c=parseInt(a.substr(j,2),16)^r;s+=String.fromCharCode(c);}s=do... 阅读全帖 |
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w*****i
发帖数: 441 | 13 来自主题: Immigration版 - 审稿机会 审稿机会，下面是大致的title。请做此领域的，若感兴趣，把简历发到zhou.422@
gmail.com
非相关专业的勿扰，谢谢
Telomerase activity, telomere length and alternative lengthening of
telomeres in renal cell carcinoma |
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l*********d
发帖数: 21519 | 15 看了偶像游士化肥科普系列，也东施效颦一把，来个小谈健康秘诀，结合自己
为了家人的健康选修了一门营养学，主要谈如何饮食，先开个引子，因为比较忙，不知
道何时能整理完，敬请大家原谅。
决定人的寿命的两大因素：
一，人只要活着就有新的细胞产生和老的细胞死去，产生新细胞由染色体复
制，然后细胞分裂，但是细胞不能无休止地分裂，细胞也有寿命。每个细胞的染色体上
有个“telomere”，中文叫端粒，每分裂一次就短一些，直到到终端，细胞的寿命就终
结，这也是人为什么终有一天会死亡，科学家已经开始研制如何延长telomere。
二，超氧化物 “superoxide”对细胞的破坏，形成细胞变异、死亡。人在消
耗能量的过程中主要采取有氧分解，在这个过程中，如果过多的氢原子，但是氧原子不
足，就会产生大量的超氧化物（H2O2），所以很多人说心宽者年轻，这也不无道理的。
人着急、生气的时候会感到胸闷，这也是肺部缺氧的一个征兆，所以经常着急、生气的
人会多产生超氧化物，就会容易短寿和变老；心宽者凡事大度，心胸开阔就会增进肺部
氧气，减少超氧化物的产... 阅读全帖 |
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S*********o
发帖数: 1334 | 16 关于二号染色体的问题很多，尚无定论，远远没有证明或者弄得像是人和黑猩猩同祖先。
比如说，如果是融合的话，理想的证明是在二号染色体上找到两个着丝粒（
centromeres，在染色体的中部），但是，Ken Miller所引用的那篇文章说：one of
the two centromeres became inactivated (2q21, which corresponds to the
centromere from chimp chromosome 13) and the centromeric structure quickly
deterioriated（LaDeana W. Hillier et al, Nature 434, 2005），换句话说，只找
到一个确定的着丝粒，另外一个只是残片，这个残片的确定可就不是那么确凿的了，文
章说：Within this 2.6-Mb interval, we identified a relatively large tract of
satellite sequence (three tracts totalling 31,198 ... 阅读全帖 |
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l****t
发帖数: 102 | 17 "for the discovery of how chromosomes are protected by telomeres and the
enzyme telomerase"
Elizabeth H. Blackburn
Carol W. Greider
Jack W. Szostak
5 October 2009
The Nobel Assembly at Karolinska Institutet has today decided to award
The Nobel Prize in Physiology or Medicine 2009 jointly to
Elizabeth H. Blackburn, Carol W. Greider and Jack W. Szostak
for the discovery of
"how chromosomes are protected by telomeres and the enzyme telomerase"
Summary
This year's Nobel Prize in Physiology or Medici |
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g*********d
发帖数: 233 | 18 Box 1. Properties of euchromatic and heterochromatic regions
Trying to define heterochromatin is like trying to define life itself: a
cluster of important properties can be specified, but there are exceptions
in every instance. For example, centromeres are usually associated with
blocks of flanking heterochromatin. However, the inner centromere of
Drosophila chromosomes is associated with blocks of nucleosomes that contain
CENP-A (also known as CID), a variant of histone H3, interspersed with
bl... 阅读全帖 |
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b****r
发帖数: 17995 | 19 这个好像挺常识的了吧，我不是做这个的但是seminar和看文献提到的还是挺多的
刚去随便搜了ncbi的review，这个摘要里就讲了“. Telomere dysfunction has been
implicated in aging and senescence, and shorter leukocyte telomere length (
LTL) has been demonstrated to predict cardiovascular disease and mortality. ”
至于是不是primary defects， 不是特别明白你指的是什么。据我所知只是确证了端粒
随着细胞分裂次数而缩短，而端粒太短与很多疾病相关现象有关，如触发凋亡或者染色
体融合，这个应该是有非常solid的实验证据的 |
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f******g
发帖数: 1003 | 20 In the fast turn-over organ, intestine, blood system, telomere gets shorter
and shorter when cell proliferate. but in slow turn orver organ, like heart,
telomere may not play an improtant role. |
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C******D
发帖数: 5 | 21 I would like to find the following 2 papers:
Holt S, Shay J, Wright W. Refining the telomere-telomerase hypothesis of
aging and cancer. Nat Biotechnol. 1996;14(7):836-836-9.
Multani A, Li C, Ozen M, Imam A, Wallace S, Pathak S. Cell-killing by
paclitaxel in a metastatic murine melanoma cell line is mediated by
extensive telomere erosion with no decrease in telomerase activity. Oncol
Rep. 1999;6(1):39-39-44.
Thank you very much! |
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C******D
发帖数: 5 | 22 I would like to find the following 2 papers:
Holt S, Shay J, Wright W. Refining the telomere-telomerase hypothesis of
aging and cancer. Nat Biotechnol. 1996;14(7):836-836-9.
Multani A, Li C, Ozen M, Imam A, Wallace S, Pathak S. Cell-killing by
paclitaxel in a metastatic murine melanoma cell line is mediated by
extensive telomere erosion with no decrease in telomerase activity. Oncol
Rep. 1999;6(1):39-39-44.
Thank you very much! |
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v*******e
发帖数: 11604 | 23
你说的恢复机制之类的，可能是指telomerase吧。生殖细胞有这个表达用来对付
telomere erosion.
细胞生存过程中，除了分裂的时候有telomere erosion问题，还有别的DNA damage问题
。生殖细胞里也不一定可以恢复，但是可以依靠自然选择（精子竞争游泳，有问题的受
精卵流产之类）。 |
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发帖数: 1 | 24 1 北京大学生命科学学院魏文胜课题组
我们使用了文章中报道的高效ssDNA，同时自己设计了其他2条针对体内其他基因位点的
ssDNA，与NgAgo表达质粒共转HEK293T细胞与HeLa细胞，2天及5天后，用T7E1检测切割
效率，这三条针对2个不同基因的ssDNA，在HEK293T和HeLa两个细胞系中，无论转染一
次还是在8到12小时后再转染一次ssDNA，都没有检测到切割。
针对敲除后能使细胞有表型变化的某特定基因，我们设计了ssDNA，与NgAgo表达质粒共
转HeLa细胞5天后，发现细胞表现出了一定的对应表型，但是把这部分细胞收集起来提
取基因组，对靶位点测序，没有发现基因组序列的任何改变。
我们针对某特定基因设计了6种ssDNA，用特异的荧光报告系统检测是否有靶点DSB产生
，结果显示所有实验组均没有检测到对靶位点DNA序列的切割活性。
2 中科院动物研究所王皓毅课题组
我们在293T细胞中表达带有Flag标签的NgAgo ，在不同时间点检测NgAgo蛋白表达。发
现转染6小时后开始检测到目的蛋白，随着时间的延长蛋白量增加。在人类293T细胞系
中重复原文章中Figure ... 阅读全帖 |
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O*******d
发帖数: 20343 | 25 你显然是生物外行，科盲。难怪那么幼稚。 要攻击进化论，先把进化论的理论搞清楚
了再发言。
1. Archidiacono, N., Storlazzi, C.T., Spalluto, C., Ricco, A.S., Marzella
, R., Rocchi, M. 1998. ‘Evolution of chromosome Y in primates.’ Chromosoma
107:241-246.
2. Britten, R.J. 2002. ‘Divergence between samples of chimpanzee and
human DNA sequences is 5% counting indels.’ Proceedings National Academy
Science 99:13633-13635.
3. Fujiyama, A., Watanabe, H., Toyoda, A., Taylor, T.D., Itoh, T., Tsai,
S.F., Park, H.S., Yaspo, M.L., Lehrach, H., C... 阅读全帖 |
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发帖数: 1 | 26 信念改命运 日医师30天抗癌成功
原标题：〝踩烂癌细胞〞信念改命运 日医师30天癌愈 综合报导 / 李小奕
点此看大图片
美国生物学家布鲁斯・立顿认为，信念在挑选我们的基因、决定我们的行为。(
pixabay)
很多从重病中康复的人几乎都有三个共同点：改变饮食、改变生活习惯，以及〝改变信
念〞。其中以人的信念尤为关键，越来越多的〝身心灵医学〞研究发现，人的情绪、信
念和思想能左右生理健康、甚至改变遗传密码（DNA）。
收藏见证历史 一窥书店老板的私人车库
收藏见证历史 一窥书店老板的私人车库
日精神科医师一个月抗癌成功
日本精神科医师渡部芳德在其书《一个月，从癌症生还》中记述，自己在一次健检中发
现肺癌。他下定决心，开始透过饮食、健走，以及运用正念来调养自己的身体。一个月
后他再回医院做检查，原本3～5公分的肿瘤竟消失无踪！
渡部芳德在书中讲述了自创的〝抗癌（想像）健走法〞。身为精神科医师，渡部芳德非
常了解情绪与疾病的关系：当人处在焦虑状态下，免疫力就会下降。于是他很快收拾自
己负面的心情，采取一种积极的〝焦虑控管〞技巧：在每日健走的时候，集中心力对抗
癌症。
〝我走在... 阅读全帖 |
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l****o
发帖数: 2909 | 27 Cambridge's Nobel Prize winners since 1996:
# 1996 James Mirrlees, Trinity College
Prize in Economics, for studying behaviour in the absence of complete
information
# 1997 John Walker, Sidney Sussex College
Nobel Prize in Chemistry, for studying how a spinning enzyme creates the
molecule that powers cells in muscles
# 1998 Amartya Sen, Trinity College
Prize in Economics, for his contributions to welfare economics
# 1998 John Pople, Trinity College
Nobel Prize in Chemistry, for the development of... 阅读全帖 |
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w*****g
发帖数: 1503 | 28 这种货色， 挫则挫矣，勇，大概他的菊花很勇吧
Yanzhong Wang
Lecturer in Medical Statistics
Background:
PhD in Statistics, University of Glasgow, 2000-2003.
Bioinformatician working on cancer genomics, University of Cambridge, 20
04-2006.
Statistician working on large epidemiological studies and clinical trial
s, Robertson Centre for Biostatistics, University of Glasgow, 2007-2009.
Research Interests:
Health Informatics, epidemiological studies and clinical trials;
Statistical genomics and genetics;... 阅读全帖 |
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p**o
发帖数: 3409 | 29 端粒(telomeres)在细胞分裂时会缩短损耗，所以任何组织和器官都有寿命。 |
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b********n
发帖数: 38600 | 30 http://washington.cbslocal.com/2014/01/08/study-racism-may-acce
Study: Racism May Accelerate Aging In African-American Men
COLLEGE PARK, Md. (CBSDC) – Accelerated aging and a greater likelihood of
suffering from an age-related illness at a younger age are two consequences
being linked to African-American men who have experienced high-levels of
racism throughout their lives.
“We examined a biomarker of systemic aging, known as leukocyte telomere
length,” Dr. David H. Chae, assistant professor of ... 阅读全帖 |
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s********e
发帖数: 2783 | 31 科学家已经成功将老年人的细胞转变成为年轻细胞，这或许让我们离永葆青春的梦想又
近了一步。据英国《每日邮报》4日报道，最近，根据美国斯坦福大学医学院的科学家
介绍，一种新的方法能够快速而有效地延长人类端粒的长度，端粒是染色体末端的保护
帽，与衰老和疾病有关。这项研究结果发表在最近的《FASEB Journal》杂志（美国实
验生物学会的旗舰杂志——观察者网）。文章通讯作者是资深的干细胞研究专家、美国
科学院院士海伦·布劳（Helen M. Blau）。
干细胞研究专家、美国科学院院士海伦·布劳（Helen M. Blau）
如何让老细胞“返老还童”，关键在于染色体末端。日前，科学家成功通过一项新技术
延长了染色体末端的长度。美国斯坦福大学的研究者称这项技术可以延长人的寿命，为
战胜衰老导致的疾病带来希望。
染色体末端的端粒是染色体端部的保护帽，它影响着人类的年龄和健康。染色体终端对
DNA起保护作用，DNA每复制一次，端粒就会变短一些，直至最终无法再保护DNA。因此
，DNA便可能受到损伤或发生突变，导致人的衰老。
一般情况下，年轻人的染色体终端大概有8000到10000个有机分子（核苷... 阅读全帖 |
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w*********g
发帖数: 30882 | 32 治疗人类衰老迈出第一步：美国科学家成功延长染色体末端
发表时间：2015-02-05 10:06:49
字号：A-AA+
关键字: 染色体染色体末端端粒染色体终端衰老青春返老还童干细胞
科学家已经成功将老年人的细胞转变成为年轻细胞，这或许让我们离永葆青春的梦想又
近了一步。据英国《每日邮报》4日报道，最近，根据美国斯坦福大学医学院的科学家
介绍，一种新的方法能够快速而有效地延长人类端粒的长度，端粒是染色体末端的保护
帽，与衰老和疾病有关。这项研究结果发表在最近的《FASEB Journal》杂志（美国实
验生物学会的旗舰杂志——观察者网）。文章通讯作者是资深的干细胞研究专家、美国
科学院院士海伦·布劳（Helen M. Blau）。
干细胞研究专家、美国科学院院士海伦·布劳（Helen M. Blau）
如何让老细胞“返老还童”，关键在于染色体末端。日前，科学家成功通过一项新技术
延长了染色体末端的长度。美国斯坦福大学的研究者称这项技术可以延长人的寿命，为
战胜衰老导致的疾病带来希望。
染色体末端的端粒是染色体端部的保护帽，它影响着人类的年龄和健康。染色体终端对
DNA起保护作用... 阅读全帖 |
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x********e
发帖数: 35261 | 33 telomere
特例是planaria，可以从个体和细胞层面自我克隆 |
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发帖数: 1 | 34 http://www.natureindex.com/news-blog/ten-institutions-that-domi
1. Chinese Academy of Sciences (CAS), China
Weighted fractional count (WFC): 1357.82
Established in 1949 in Beijing, the Chinese Academy of Sciences (CAS) is the
world’s largest scientific organisation, comprising 114 institutes and 48,
500 researchers. In 2015 its scientists made the largest contribution to
high-quality research included in the index, a contribution that’s grown by
a compound annual growth rate of 6.8% since 2012. ... 阅读全帖 |
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s****e
发帖数: 7018 | 35 刚刚知道细胞里面的 telomere 约束基因复制的时候，
好多人认为终于找到永生的秘密了
结果永生到现在还是泡影 |
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w********2
发帖数: 632 | 36 MGEs are drivers of genomic and biological diversity (Böhne et al.,
2008) and play a significant role in HGT in several ways:
(1) MGEshaveevolvedmechanismsthatenhancethepo- tential for gene transfer
between organisms. For ex- ample, conjugative elements have evolved highly
ef- ficient mechanisms for the passage of genes into a recipient cell.
(2) MGEs can alter the function of genes in the vicin- ity of the insertion
in the host genome. These alter- ations can include disruption or
inactiva... 阅读全帖 |
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S*****n
发帖数: 4185 | 37 要破解这个有什么思路？
叔认为一个思路是绕开这个Telomere，用其他外部机制替代，就可以长生不老了。 |
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发帖数: 1 | 38 本千老告诉你，人老死的原因是器官衰竭，器官衰竭的原因跟电脑CPU用的太久挂了的
原因是一样的，磨损了。人和电脑不一样的地方是人的细胞可以繁殖复制，但是有些器
官比如心和脑子，结构太复杂，需要在发育的时候一次成型，类似倒模，倒模成型了就
不能替换里面的部件了，除非彻底把它拆了，所以就算单个细胞可以繁殖更新也没有用。
只要解决器官替换，人就可以无穷无尽的活下去。
但是你最后会遇到泰修斯之船的哲学问题，一艘船，所有部件全都换过，还是同一艘船
吗？人体同理。
: 要破解这个有什么思路？
: 叔认为一个思路是绕开这个Telomere，用其他外部机制替代，就可以长生不老了。
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x********e
发帖数: 35261 | 39 当然不。在生物学和病毒学上，polyA的长度影响病毒蛋白的表达，越长越好。病毒的
polyA应该跟telomere一样，越来越短。 |
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p**j
发帖数: 7063 | 40 【 以下文字转载自 Military 讨论区 】
发信人: beijingren (to thine own self be true), 信区: Military
标 题: 种族歧视导致黑人衰老. 你妈，这种研究也有Funding?
发信站: BBS 未名空间站 (Thu Jan 9 10:13:47 2014, 美东)
http://washington.cbslocal.com/2014/01/08/study-racism-may-acce
Study: Racism May Accelerate Aging In African-American Men
COLLEGE PARK, Md. (CBSDC) – Accelerated aging and a greater likelihood of
suffering from an age-related illness at a younger age are two consequences
being linked to African-American men who have experienced high... 阅读全帖 |
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b*****t
发帖数: 31 | 41 【 以下文字转载自 Biology 讨论区 】
发信人: bluebat (蓝蝙蝠), 信区: Biology
标 题: positions in Hangzhou China
发信站: BBS 未名空间站 (Fri Jan 21 13:24:37 2011, 美东)
代友发文，请勿回复到本人站内信箱。
Institute of Aging Research in Hangzhou, China is of several positions at
different levels in the research areas of neurological, ovarian, and bone
marrow disorders in animal models. In addition, there are also focused
research interests in telomeres and telomerase in aging, stem cells and
cancer at the Institute of Aging Research, Hangzhou Nor... 阅读全帖 |
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w******y
发帖数: 6 | 42 土博，美国postdoc第4年
生化方向，背景如下
文章四篇，其中第一作者两篇，
1st author, IF~8, 2007, citation 75
1st author, IF~10, 2011, citation 0
2st author, IF~4, 2007, citation 6
3st author, IF~8, 2010, citation 5
准备申请Eb1a和NIW，现无任何审稿，正在给编辑写信攒审稿机会中
现急求review 机会, 领域是telomere ， DNA structure and epigenetics.
各位看看如果我能把 review弄上去的话够EB1a吗?另外文章数量是不是太少了？
另问，要被多少杂志加入reviewer list一般才够，加入reviewer list后多久才能收到
审稿机会？ 谢谢 |
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t*****r
发帖数: 107 | 43 To Whom It May Concern:
I am Dr. xxxx, an editor of XXX. FEBS letters is owned by XXX(Federation
Biochemical Societies), one of the largest organizations in XXX, with nearly
XXX members distributed among 36 Constituent Societies and 7 Associated
Member Societies in 43 countries. XXX is one of the world's leading journals
in XXX and is XXX.
To ensure the rapid publications with high quality, we carefully recruit
scientists with outstanding credentials as manuscript reviewers. The ability
to judge... 阅读全帖 |
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i**n
发帖数: 1481 | 44 http://www.news.com.au/story/0,27574,26170217-421,00.html
* Aussie biologist wins Nobel prize
* Pioneering work in ageing and disease
* Win is a first for an Australian woman
MOLECULAR biologist Elizabeth Blackburn has become the first Australian
woman to win a Nobel prize.
Professor Blackburn, whose pioneering work on telomeres - protective caps on
the ends of chromosomes - has opened up new lines of inquiry into growth,
ageing and disease, is the 2009 Nobel laureate for physiology |
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发帖数: 1 | 45 “踩烂癌细胞”信念改命运 日医师30天癌愈
综合报导 / 李小奕
美国生物学家布鲁斯·立顿认为，信念在挑选我们的基因、决定我们的行为。（
shutterstock)
很多从重病中康复的人几乎都有三个共同点：改变饮食、改变生活习惯，以及“改变信
念”。其中以人的信念尤为关键，越来越多的“身心灵医学”研究发现，人的情绪、信
念和思想能左右生理健康、甚至改变遗传密码（DNA）。
日精神科医师一个月抗癌成功
日本精神科医师渡部芳德在其书《一个月，从癌症生还》中记述，自己在一次健检中发
现肺癌。他下定决心，开始透过饮食、健走，以及运用正念来调养自己的身体。一个月
后他再回医院做检查，原本3～5公分的肿瘤竟消失无踪！
渡部芳德在书中讲述了自创的“抗癌（想像）健走法”。身为精神科医师，渡部芳德非
常了解情绪与疾病的关系：当人处在焦虑状态下，免疫力就会下降。于是他很快收拾自
己负面的心情，采取一种积极的“焦虑控管”技巧：在每日健走的时候，集中心力对抗
癌症。
“我走在喜欢的路途上，每走一步就想像自己用力踩烂癌细胞。”他说：“每天持续这
个方法，想像力就变得越来越清晰。我的脑海里开始浮现癌细胞被踩烂的具... 阅读全帖 |
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b**********5
发帖数: 7881 | 46 Children born to older fathers 'are more likely to be ugly'... but may also
live longer
Older fathers have uglier children, researchers have claimed after linking
age to genetic mutations.
The finding comes weeks after leading scientists reported children born to
men over the age of 45 run a higher risk of having autism and psychiatric
disorders.
With age, sperm-producing cells do not copy a man's DNA as effectively,
leading to genetic mutations.
Martin Fielder, an anthropologist at Vienna Unive... 阅读全帖 |
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f****s
发帖数: 145 | 47 Not exactly true. For body building, a high protein diet is usually recommen
ded. However, a high protein diet is not healthy for the kidney in the long
run and easy to trigger inflammation. Multiple studies have shown that calor
ie restricted mice live longer than mice with regular diet.
I personally still believe that human body is like a machine with limited se
lf-repair function. As cells divide by themselves (maybe after 50 passages?
), there will be an accumulation of all kinds of problems... 阅读全帖 |
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f****s
发帖数: 145 | 48 前一阵JAMA上有篇文章说鱼油还可以防止telomere缩短，间接延长寿命。
多吃点没错。 |
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