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s******y
发帖数: 28562 | 2 David Venet from the Université Libre de Bruxelles 用胡乱挑选的基因组合
和已经发表的所谓的癌基因的marker 用在未知的病人的数据上，发现胡乱挑选
的基因的准确率比那些所谓的marker 还要好。
文章结尾直接点了几个杂志的名：Cell, Nature Genetics, PNAS, 认为这些杂志
过分鼓吹所谓的 gene marker 的意义。从文章里面的行文来看，估计这些也是
把这个文章据掉的杂志 （lol)
文章最后发表在
PLoS Comput Biol. 2011 Oct;7(10):e1002240. Epub 2011 Oct 20.
http://blog.f1000.com/2012/01/10/random-gene-sets-can-predict-b
Random gene sets can predict breast cancer survival better than cancer-
related signatures
And top-tier journals did not want to pu... 阅读全帖 |
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s******y
发帖数: 28562 | 3 David Venet from the Université Libre de Bruxelles 用胡乱挑选的基因组合
和已经发表的所谓的癌基因的marker 用在未知的病人的数据上，发现胡乱挑选
的基因的准确率比那些所谓的marker 还要好。
文章结尾直接点了几个杂志的名：Cell, Nature Genetics, PNAS, 认为这些杂志
过分鼓吹所谓的 gene marker 的意义。从文章里面的行文来看，估计这些也是
把这个文章据掉的杂志 （lol)
文章最后发表在
PLoS Comput Biol. 2011 Oct;7(10):e1002240. Epub 2011 Oct 20.
http://blog.f1000.com/2012/01/10/random-gene-sets-can-predict-b
Random gene sets can predict breast cancer survival better than cancer-
related signatures
And top-tier journals did not want to pu... 阅读全帖 |
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F******y
发帖数: 1988 | 4 Clin Physiol Funct Imaging. 2002 Sep;22(5):312-9.
Decreased actin solubility observed during ATP-depletion is mimicked by
severing agents but not depolymerizing agents in isolated and cultured
proximal tubular cells.
To : f*************[email protected]
5黄包子，呵呵 |
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c*******n
发帖数: 82 | 9 Successful Intercalation into Multiwall Carbon Nanotubes without Breaking
Tubular Structure
Molecular Crystals and Liquid Crystals
Volume 310, 1998, Pages 159 - 164
Authors: V. Z. Mordkovicha; M. Baxendaleb; M. Yudasakab; S. Yoshimurab; J. -
Y. Daic; R. P. H. Changc
DOI: 10.1080/10587259808045330
http://www.informaworld.com/smpp/content~db=all~content=a757854
Email:c*******[email protected]
Thanks |
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l****y
发帖数: 92 | 10 请教各位,在下面这些cv的方向中,哪个比较热门,好找工作啊?
Computational Mechanics
Concrete Structures
Steel Structures
Composite Structures
Tubular Structures
Structural Mechanics
Structural Forensics
Repair of Structures
Earthquake Engineering
Bridge Engineering
Concrete Materials
Building Science
Construction Management
GeoMechanics
Rock Engineering
Soil Engineering
Mining Geomechanics
Geomatics Engineering
Water and Wasterwater Treatment
Enviroment Management
Water Resources, Hydrology, Hydraulics
Groundwater
Sustainab |
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m***n
发帖数: 266 | 11 现在nerve regeneration大都是通过tubular scaffold来控制方向和pattern
如果没有scaffold,怎样来实现指哪长哪？不管in vitro 还是in vivo。
在胚胎发育过程中，血管和神经总是同时并行发育的，两者可以互相调控。 |
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l********e
发帖数: 3632 | 12 yes,
for points CLOSE to M, this is always true, it's called
"Tubular neighborhood theorem"
Of course, you must assume M is smooth(at least the tangent space must exsit) |
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R********n
发帖数: 519 | 13 太赞了！谢谢大牛，呵呵，我刚google到了这个Tubular neighborhood theorem
我想要这个结论的出发点是因为一个猜测，本来也不知道对不对，但感觉有了你说的这
个theorem，应该是对的？:-)
对于一个属于R^D的smooth Riemannian manifold M，如果我们以某个分布 P 在M上面
sampling点得到x，然后对x加上R^D空间各向同性的正态噪声e，得到y=x+e
另一方面，如果在M上以另一个分布P'在M上sampling点得到x'，然后对x'加上在x'的
normal space里的各项同性的正态噪声e'，得到y'=x'+e'
猜测是，如果正态噪声e的方差不是太大，我们通过选择分布P'和e'的方差，
可以使得y和y'的在R^D空间的分布是一样的
exsit) |
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h******l
发帖数: 238 | 14 Immunofluorescence Microscope: Five glomeruli are present; granular
deposition along the mesangium and capillary wall:
Ig G-; IgM+ -; Ig A + -; C3 -; F +; C1q + -
HE stain: 5 glomeruli are examined, three show partial sclerosis, one shows global sclerosis. Mild to moderate mesangial proliferation are present in most glomeruli, with 2 to 6 cells in each mesangial segment. The mesangial matrix is proliferated and expanded. The capillary wall is a relatively normal. Tubular epithelial cells show s |
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o**h
发帖数: 55 | 15 A MAOi taker presents in ER with hypertensive crisis after drinking.
Alert patient, Nifedipine.
Unconscious patient,Labetalol.
preventive therapy of cluster headache,: Cab
Viral agents are factors contributing to the development of RA
To confirm urine in a urine leak: measuring the creatinine level.
In winter, intermittent headache, joint pain, nausea
next step in mx: checking arterial blood gas.
renal tubular acidosis
type I: low potassiun
type II: maybe hypophosphatemia
type IV: high potassium |
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z****o
发帖数: 368 | 16 An asymptomatic 56-year-old woman has occult blood in her stool. Barium
studies of her transverse colon show an intraluminal mass. The surgical
specimen is shown. Which of the following is the most likely diagnosis?
A. Adenocarcinoma
B. Carcinoid tumor
C. Polypoid leiomyoma
D. Tubular adenoma
E. Villous adenoma
病例图片请见附上的文件。是不是因为出现隐血，所以一定就是恶性了？或者adenoma
会不会出血？ |
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d****y
发帖数: 2180 | 17 我第1个反应就是carcinoma，不过看了图后觉得这个肿块不象那么恶性的。
刚好在看RRP，查了一个Gastrointestinal disorders,嘿嘿，有个图跟这个几乎一样，
是D; Tubular adenoma. |
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d****y
发帖数: 2180 | 18 Adenocarcinoma: crater-like(象火山口的）, reddish, irregularly-shaped tumor
Tubular adenoma: most common polyp, the head of the stalked polyp has a
lobulated, mushroom-like appearance.
This is consitent with the figure presented in the question. The stalk of
the polyp is just under the mushroom-like head.
The adenoma has a great chance to develop into maglinant carcinoma since the
adenoma >2cm. |
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s******t
发帖数: 579 | 19 If you look at the pitcure carefully, you will find that it is an adenomatous
polyp (tubular adenoma) attached to the lumen by a stalk. It is round and w
/ a smooth surface. Polyps can cause rectal bleeding too.
I go with daisy. |
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l*********0
发帖数: 85 | 20 I will make change, D is correct, not A.
The following somehow useful, according to this, this woman has 20% of
chance to be cancer. Just make clear, tubular or villus will be determined
by microscope, not by eye.
What is a colon polyp?
Colon polyps are fleshy growths that occur on the inside (the lining) of the
large intestine, also known as the colon. Polyps in the colon are extremely
common, and their incidence increases as individuals get older. It is
estimated that 50% of the people over th |
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p******9
发帖数: 114 | 21 1. A 5-year-old boy is brought to the physician 1 hour after urinating
bright red blood. He has been taking ibuprofen since injuring his right
flank while wrestling with friends yesterday; he also has been taking
penicillin for 3 days for streptococcal pharyngitis. His temperature is 36.7
C (98 F), blood pressure is 90/48mm Hg, pulse is 108/min, and respirations
are 18/min. Examination shows purple ecchymoses over the shins and right
flank; there is tenderness of the right costovertebral area. T... 阅读全帖 |
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L********a
发帖数: 576 | 22 A 42 year old man is admitted to the local hospital with a diagnosis of deep
vein thrombosis. On physical exam, he has bilateral pitting edema of the
lower extremities. On standard chemistry testing, his albumin is 2.5g/dl.
During further interview, the patient states that this past year he noticed
he had more "cold" than usual. A 24 hour urinalysis shows 4 g of protein
with no hematuria or red blood cells. If a renal biopsy is performed, which
of the following findings would be expected?
A) Nor... 阅读全帖 |
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l**x
发帖数: 296 | 23 III score 8 is high grade, not good
Low grade: score 3-5
Intermediate grade: score 6,7
High grade: score 8,9
This is histological grading of invasive ductal carcinoma of breast, based on tubular formation, mitotic count, and nuclear grade.
The link is about cancer staging, which means how extensive the tumor is involved, eg if there is axillary lymph node involved, if there's distant metastasis. |
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j******g
发帖数: 171 | 24 I went nuts this morning, for two cases. Share your responses, and I'll give
what I did and found at the end. It is hoped that you'd learn something
through the practical components of pathology.
1 case. A biopsy of transverse colon only contains piece of fat with some
cautery/crush artifact. What will you do?
2 case. A biopsy of colon polyp has a fragmented typical tubular adenoma.
However, in the early afternoon, I got additional slides for the same case
with the same label! Now I have two sli... 阅读全帖 |
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j******g
发帖数: 171 | 25 1 case. A biopsy of transverse colon only contains piece of fat with some
cautery/crush artifact. What will you do?
A. Go check block against slide/
B. Go check the container including the lid(!). And filter the contents into
another block (wrap with filter paper or mesh bag).
C. If the block matched with slide and the remaining contents does not have
anything meaningful, call the MD to tell the situation and ask for his/her
input. In fact, he said "Oh, I thought it was a lipoma and thank you fo... 阅读全帖 |
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z**********o
发帖数: 106 | 26 Can anyone give the correct answer for the following two questions? thanks!
Q25
a 45-year old man has four episodes of involuntary twitch of the right foot.
following the last episodes, he had a tonic-clonic seizure. Which of the
following structures on the left is the most likely origin of the seizure?
A. inferior frontal cortex
B. inferior temporal cortex
c. insular cortex
D. Primary motor cortex
E. Supplementary motor cortex
I think B is the correct answer. For partial seizures, most common... 阅读全帖 |
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J**b
发帖数: 182 | 27 1. Sarah is recovering from pneumonia. She is 93 and a resident of a local
nursing home, where she was diagnosed with behavioral and cognitive
disturbances. She is refusing food, drink and medication. Her BUN is 60
and her serum Creatinine is 1.0 . Her potassium level is 4.8.
Which of the following is most likely to be true?
A. Her serum creatinine is “normal” because her kidneys have not
been injured
B. Her renal function will return to normal with adequate rehydration
... 阅读全帖 |
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J**b
发帖数: 182 | 28 这是我试着选的答案，如果哪位兄弟姐妹同意我的一个答案，答谢一个包子，指正一个
错误，2个包子。
1. Sarah is recovering from pneumonia. She is 93 and a resident of a local
nursing home, where she was diagnosed with behavioral and cognitive
disturbances. She is refusing food, drink and medication. Her BUN is 60
and her serum Creatinine is 1.0 . Her potassium level is 4.8.
Which of the following is most likely to be true?
A. Her serum creatinine is “normal” because her kidneys have not
been injured
B. Her renal function wil... 阅读全帖 |
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J*********4
发帖数: 1274 | 29 一家之言, just for discussion
1. C, 2. C, 3.don't know 4. E, 5.C, 6.C, 7.B, 8.E
1. The old lady has dehydration, which causes pre-renal azotemia and
eventrually leads to renal tubule necrosis. The low creatinine is due to the
lack of muscle mass in old people, which underestimates the actual renal
insufficiency.
8. RBC cast indicates damage in GBM. Here is a paragraph from wiki
Hyaline casts
The most common type of cast, hyaline casts are solidified Tamm-Horsfall
mucoprotein secreted from the tubula... 阅读全帖 |
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U******u
发帖数: 5829 | 30 发信人: USMedEdu (US_CMGs), 信区: Pre_Resident_Club
标 题: Summary for externship with Dr. He's program
发信站: BBS 未名空间站 (Thu Sep 10 01:07:41 2015, 美东)
Summary for externship with Dr. He's program
CHZ
It was a difficult decision for me to have an externship in New York
this summer. I had to leave work without payment, and I am also the
only person earning money for my family. However, I believe it was
very important for me, a truly old CMG, to have the special training
from Dr. He, a medical education s... 阅读全帖 |
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U******u
发帖数: 5829 | 31 发信人: USMedEdu (US_CMGs), 信区: Pre_Resident_Club
标 题: Summary for externship with Dr. He's program
发信站: BBS 未名空间站 (Thu Sep 10 01:07:41 2015, 美东)
Summary for externship with Dr. He's program
CHZ
It was a difficult decision for me to have an externship in New York
this summer. I had to leave work without payment, and I am also the
only person earning money for my family. However, I believe it was
very important for me, a truly old CMG, to have the special training
from Dr. He, a medical education s... 阅读全帖 |
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T****g
发帖数: 705 | 32 “临床思维，解题思路”
举个例子：
An 82 year-old man has been mechanically ventilated in the hospital for the
past 48 hours because of an exacerbation of chronic obstructive pulmonary
disease. He has passed no urine since removal of a urinary catheter 12 hours
ago. Current medications include intravenous methylprednisolone and
albuterol, ipratropium. And fluticasone by inhalation. Which of the
following is the most likely diagnosis?
A) Acute interstitial nephritis
B) Acute urethral obstruction
C) Contr... 阅读全帖 |
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r********n
发帖数: 149 | 33 单体燃料电池只能产生1V左右电压，功率有限，为了使得SOFC具有实际应用可能，需要
大大提高SOFC的功率。
可以应用的方式：将若干个单电池以各种方式（串联、并联、混联）组装成电池组。目
前SOFC组的结构主要为：管状（tubular）、平板型（planar）和整体型（unique）三
种，其中平板型因功率密度高和制作成本低而成为SOFC的发展趋势。
1、管状SOFC
管状结构SOFC是最早发展的一种形式，也是目前较为成熟的一种形式。单电池由一端封
闭、一端开口的管子构成，如图2a所示。最内层是多孔支撑管，由里向外依次是阴极、
电解质和阳极薄膜。氧气从管芯输入，燃料气通过管子外壁供给。
目前管状结构单电池已经运行了数万小时。单电池通过阴、阳极间连接形成电池堆，如
图2b所示。
资料来源：彭苏萍等，物理 2004 33（2） 90～94：固体氧化物燃料电池
2、平板型SOFC
平板型固体氧化物燃料电池的几何形状简单，其设计形状使得制作工艺大为简化。平板
式SOFC结构组成如图3a所示。阳极、电解质、阴极薄膜组成单体电池，两边带槽的连接
体连接相邻阴极和阳极，并在两侧提供气体通道，同时隔开 |
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s**********8
发帖数: 25265 | 34 来自主题: MedicalDevice版 - stent http://en.wikipedia.org/wiki/Stent
Stent
From Wikipedia, the free encyclopedia
For people named Stent, see Stent (surname).
Stent
Intervention
MeSH
D015607
In the technical vocabulary of medicine, a stent is an artificial 'tube'
inserted into a natural passage/conduit in the body to prevent, or
counteract, a disease-induced, localized flow constriction. The term may
also refer to a tube used to temporarily hold such a natural conduit open to
allow access for surgery.
Contents
[hide] 1 Etymology
... 阅读全帖 |
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C*****D
发帖数: 1299 | 35 z这个没法彻底解决。 像律师样按实际时间收，更难。
我们看tubular adenoma 只要30秒， 但炎症要几分钟到几十分钟，但RVU 是一样的。
平均后是一样的。问题是，有人钻空子，只做RVU 高的。
像美国卖西瓜，按个不按分量，如果大家都拼命捡大的，系统就会乱。 |
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C*****D
发帖数: 1299 | 36 z这个没法彻底解决。 像律师样按实际时间收，更难。
我们看tubular adenoma 只要30秒， 但炎症要几分钟到几十分钟，但RVU 是一样的。
平均后是一样的。问题是，有人钻空子，只做RVU 高的。
像美国卖西瓜，按个不按分量，如果大家都拼命捡大的，系统就会乱。 |
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h***y
发帖数: 834 | 37 关于dilantin，刚去看了一下pfizer的网页：
Unusually high levels result from liver disease, congenital enzyme
deficiency, or drug interactions which result in metabolic interference. The
patient with large variations in phenytoin plasma levels, despite standard
doses, presents a difficult clinical problem. Serum level determinations in
such patients may be particularly helpful. As phenytoin is highly protein
bound, free phenytoin levels may be altered in patients whose protein
binding characteristics differ fr... 阅读全帖 |
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b******a
发帖数: 704 | 38 Lampl, C. and K. Yazdi (2002). "Central pontine myelinolysis." Eur Neurol 47
(1): 3-10
The etiology and pathogenesis of this disorder are unclear and will be
discussed. Chronic alcoholism is still the most common underlying condition
of CPM patients. In the literature, 174 cases of CPM have been reported in
alcoholics since 1986, which is equivalent to an incidence of 39.4%.
Likewise, 95 cases of CPM following the correction of hyponatremia have been
documented since 1986 (21.5%). The role of h... 阅读全帖 |
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m******r
发帖数: 9604 | 39 早上没有为了训练而训练：先开去朋友家还车，再跑6.5k回家；然后骑车24k去公司，
把车装汽车里开走。骑车的时候被扎了胎
中午捡了个hot deal：600刀买了一对404 tubular carbon wheels，带cassette，粘好
的管胎，还有1条备胎。 |
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i*********5
发帖数: 19210 | 40 车轮还是齿轮？
车轮都是兼容的，只要看清楚是Tubular还是Clincher，是700c还是650c。还有就是内胎的valve有长有短，别买短了就行。碳刀的长（参照ZIPP 404，808），普通圈的短。 |
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i*********5
发帖数: 19210 | 41 tubular (as oppose to clincher, the regular outer tire + inner tube) |
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i*********5
发帖数: 19210 | 44 前轮辐条少，后轮辐条多。后轮左边（non-drive）空间多，右边（drive）空间少，因
此左右编法也不一样。
大多数轮组的编法如下：
Front Spoke Pattern : Radial
Rear Spoke Pattern Non-Drive : Cross
Rear Spoke Pattern Drive : Radial
http://zipp.com/wheels/808-firecrest-tubular/ |
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i*********5
发帖数: 19210 | 45 前轮辐条少，后轮辐条多。后轮左边（non-drive）空间多，右边（drive）空间少，因
此左右编法也不一样。
大多数轮组的编法如下：
Front Spoke Pattern : Radial
Rear Spoke Pattern Non-Drive : Cross
Rear Spoke Pattern Drive : Radial
http://zipp.com/wheels/808-firecrest-tubular/ |
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R*****s
发帖数: 41236 | 46 然，版面有男人帮趋势，赶紧把你喊出来 ：）
买了个烂气筒，还在纠结要不要上铁哥说的那个fancy的。。
据说tubular的轮子要打到200psi.. |
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R*****s
发帖数: 41236 | 47 然，版面有男人帮趋势，赶紧把你喊出来 ：）
买了个烂气筒，还在纠结要不要上铁哥说的那个fancy的。。
据说tubular的轮子要打到200psi.. |
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R*****s
发帖数: 41236 | 48 一般是700c, 我其实也不知道多大，wiki了一下，似乎直径是一样大的：
http://en.wikipedia.org/wiki/Bicycle_wheel#700C_Road_bicycle_wh
29 inch wheels/ISO 622
Main article: 29er (bicycle)
“29-inch wheels”, which also conform to the popular 700C (622 mm diameter
clincher wheel standard) are becoming more popular for not only cyclocross
bikes but also cross-country mountain bikes for larger riders. Their rim
diameter of 622 mm (~24.5 inch) is identical to most road, hybrid and
touring bicycle wheels but are typically reinforced fo... 阅读全帖 |
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m******r
发帖数: 9604 | 49 【 以下文字转载自 Cycling 讨论区 】
发信人: manyhuar (许多花儿), 信区: Cycling
标 题: 404 管胎轮组$600/求建议/急/在线等
发信站: BBS 未名空间站 (Sat Dec 17 10:58:45 2011, 美东)
ZIPP 404 Carbon Race Wheels in excellent condition with less than 300 miles.
Raced only about 5 or 6 times(Olympic Distance). No damage whatsoever.
Includes Continental tubular tires in excellent condition and ready to race!
$600 firm |
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R*****s
发帖数: 41236 | 50 【 以下文字转载自 Cycling 讨论区 】
发信人: Rodimus (变叔- 似水流年), 信区: Cycling
标 题: Zipp 404 Aluminum Clincher Wheelset
发信站: BBS 未名空间站 (Wed Jan 11 11:40:28 2012, 美东)
早上看邮件，看到这么个咚咚：
http://www.nytro.com/index.cfm/product/?ProductID=7867
Aerodynamics - time and watt savings over 40K for 404 Firecrest Wheelset: 80
seconds / 27 watts.
貌似比碳轮还快？如果是真的话，这个比tubular便宜又方便啊？大牛怎么看？ |
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