g*2 发帖数: 658 | 1 Popliteal pain or pressure — Popliteal pain or pressure can accompany any
of the above pain patterns (anterior, medial, lateral knee pain). It is most
commonly caused by the buildup of pressure from a large, acute effusion.
When the patient flexes the knee in the presence of an effusion, the
quadriceps mechanism forces the fluid posteriorly. Pressure is exerted on
the gastrocnemius muscle, vascular structures, and the branches of the
sciatic nerve, leading to local pain, lower extremity edema, a... 阅读全帖 |
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g***e 发帖数: 14217 | 2 借楼转一篇理性分析转基因的文章
作者:WeiIan Ye,Head of the Vascular Biology Program at Genentech (
Genentech是历史最久规模最大的生物制药公司)
首先,现代自然的食用植物很多是经过人类几百甚至几千年的基因改造而形成的。天然
的植物产量太少,养不活这么大的人口,比如水稻杂交其实就是一种基因工程,只是采
用的是传统方法,所以很多人没有意识到这是“人造”的产品。我们很多人已经不知不
觉地吃了不少基因改造过的食物,比如无籽西瓜、苹果梨,等等。所谓转基因,只是把
基因改造的过程急速加快,用了现代技术把想要的基因放进了种子里。
第一代转基因农作物主要是为了增加作物生长优势,转进去的基因使农作物有抗虫或抗
病毒的能力,或者增强对除草剂的耐受性。
第二代转基因农作物还改造一些能提高营养成分的基因,比如有些转基因黄豆产的油会
比较能抗氧化,从而使豆油产量增加,并增长油的保存期。
虽然美国的转基因农作物都经过安全检验,很多人还是担心转基因农作物的安全性。下
面针对最主要的而且有科学依据的几点担忧评价一下:
1)转进食物里的基因会不会传到... 阅读全帖 |
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c**i 发帖数: 6973 | 3 You are a keen observer, regarding Cuban doctors. But 只知其一不知其二.
Joel Millman, New Prize in Cold War: Cuban Doctors. Wall Street Journal, Jan
15, 2011.
http://online.wsj.com/article/SB1000142
4052970203731004576045640711118766.html
Quote:
"triggering defections of Cuban medical personnel all over the globe—an
average of one a day since the U.S. countermeasure began in 2006. Cuba
generally doesn't include doctors among the 20,000 or more Cubans it
authorizes to immigrate to the U.S. each year.
"Th... 阅读全帖 |
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p********3 发帖数: 5750 | 4 50, 70, 71; 大家注意一下和这几篇文献相关的话题。 另外, 73-75我本人没有看,确实是谈的印度药材, 我在查阅参考文献的时候在搜索Chinese Medicine的时候, 显示有这些文献,我本人没有亲自看这些文献, 也许其中有讲中药的地方。不过这不影响我要表达的意思。
慢慢看:
INTRODUCTION — Plants have been used for medicinal purposes for thousands
of years. All major cultures including Native American, European, South
American, Asian, and African cultures have used botanicals for healing
purposes. As an example, saw palmetto was used for urinary symptoms in men
from Egypt in the 15th century BC [1]. Hippocrates documented... 阅读全帖 |
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D*******a 发帖数: 1723 | 5 http://apps.who.int/medicinedocs/en/d/Js4926e/5.html
Acupuncture: Review and Analysis of Reports on Controlled Clinical Trials
3. Diseases and disorders that can be treated with acupuncture
The diseases or disorders for which acupuncture therapy has been tested in
controlled clinical trials reported in the recent literature can be
classified into four categories as shown below.
1. Diseases, symptoms or conditions for which acupuncture has been proved-
through controlled trials-to be an effec... 阅读全帖 |
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h********m 发帖数: 14 | 6 请帮忙转求医问药版和我爱宝宝版
我孩子今年5岁3个月,男孩。出生于东海岸,一直在东海岸生活到1岁搬到西海岸。2岁
开始出现了一系列的症状,开始突然半夜腹痛,后来便秘超过2个星期,再后来出现便
秘,腹泻,腹胀等各种症状交替发生。
在过去的3年多已经,已经进行了一系列的therapy (speech, OT, ABA等)基本无效。
也尝试了各种diet,GFCF,SCD,FODmap等,基本没解决问题,biocidin,
Saccharomyces boulardii 有一点效果(但有限)。无克罗病家族史。
他最主要的一个症状就是肚子的气非常的多,腹胀。早上起床的时候肚子是非常的小 (
正常的),后来就越来越大,一直大到好像带了一个大气球!!!!
我们进行了很多的测试,在美国正规的儿科儿童医院基本没查出问题。我们查了无数的
资料,也基本没发现什么跟他相似的小孩。现在抱着最后一丝希望上Mit来问一下,希
望能得到一点信息。如果大家都听说过类似案例,或者有肠胃科医生给点意见,又或者
有不错的医生推荐,都非常感谢!
最近我们又看了一个小儿肠胃专科,初步诊断是回肠炎,据说绝大部分的回肠炎都属于
C... 阅读全帖 |
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l******k 发帖数: 27533 | 7 有呀
dementia主要是因为alzheimer,但也可能由vascular disease引起
大脑的血管损伤不分年龄,年纪大的人出现几率更高而已 |
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d***a 发帖数: 316 | 8 没什么可怕的,对于需要器官移植的人来说,是梦寐以求的。
Nature Medecine. 2008 Feb;14(2):213-21. Epub 2008 Jan 13.
Perfusion-decellularized matrix: using nature's platform to engineer a
bioartificial heart.
Ott HC, Matthiesen TS, Goh SK, Black LD, Kren SM, Netoff TI, Taylor DA.
Department of Surgery, Massachusetts General Hospital, Harvard Medical
School, 55 Fruit Street, Boston, Massachusetts 02114, USA.
Abstract
About 3,000 individuals in the United States are awaiting a donor heart;
worldwide, 22 million individuals are ... 阅读全帖 |
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a******9 发帖数: 1192 | 9 【 以下文字转载自 Military 讨论区 】
发信人: pertain99 (pertain), 信区: Military
标 题: 女码农外F出钱养洋老公,被割器官卖钱
发信站: BBS 未名空间站 (Sat Feb 28 14:53:12 2015, 美东)
/post-outseachina-86246-2.shtml
救我 救我,美国医院拿我做手术实验 并盗取器官弄残我
[楼主:散落海角的技工] [只看楼主]
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2014-09-17 00:52:00
我成长在一个单纯的环境中,从来不去害人 从来都很相信人世间的美好善良 但是
我自己也很容易被骗被害。
我原来是从事软件工作,有稳定的生活和收入。于是我碰到了我的第一个丈夫,在
他的欺骗下,我们结婚了。婚后 我不顾家人和反对 并和家人断绝了关系 跟着他来了
美国,我原以为我的美好生活就此开始了 我憧憬的美好的生活。我慢慢发现他是个小
人,没有才干,人小气鬼又吝啬鬼。他心胸狭窄,因为我收入高,平时工作忙。他当时
还在上学,没有收入,为了满足心里上的平衡,不仅利用我来完成他的学业,还在生活
中时... 阅读全帖 |
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l*****a 发帖数: 38403 | 10 Plants are able to remember information and react to it, thanks to an
internal communications system that can be likened to a central nervous
system in animals, according to a new study by a Polish plant biologist.
Plants "remember" information about light, and a certain type of cell
transmits that information, much like nerves do in animals.
In the study, which was published in the early online version of the
journal Plant Cell July 16, the researchers found that light shone on
one leaf of an A... 阅读全帖 |
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x**h 发帖数: 173 | 11 Two Ph.D. research assistantships are available in the Laboratory of Applied
Dynamics at the University of Tennessee Knoxville (www.utk.edu). Areas of
interest include
1.) Computational cardiology: build mathematical models of cardiac tissue to
understand how excitation waves develop unstably and heterogeneously,
leading to fibrillation.
2.) Biomechanics: investigate mechanics and vibration problems in physiology
, including vascular mechanics and human body dynamics.
Candidates with a master de |
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x**h 发帖数: 173 | 12 Two Ph.D. research assistantships are available in the Laboratory of Applied
Dynamics at the University of Tennessee Knoxville (www.utk.edu). Areas of
interest include
1.) Computational cardiology: build mathematical models of cardiac tissue to
understand how excitation waves develop unstably and heterogeneously,
leading to fibrillation.
2.) Biomechanics: investigate mechanics and vibration problems in physiology
, including vascular mechanics and human body dynamics.
Candidates with a master de |
|
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x**h 发帖数: 173 | 14 Two Ph.D. research assistantships are available in the Laboratory of Applied
Dynamics at the University of Tennessee Knoxville (www.utk.edu). Areas of
interest include
1.) Computational cardiology: build mathematical models of cardiac tissue to
understand how excitation waves develop unstably and heterogeneously,
leading to fibrillation.
2.) Biomechanics: investigate mechanics and vibration problems in physiology
, including vascular mechanics and human body dynamics.
Candidates with a master de |
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T**********e 发帖数: 29576 | 15 下面这篇文章对Jobs的胰腺内分泌癌治疗总结的不错,看来死的有点冤。
1. 10-2003 确诊,07-2004终于手术切除,期间Jobs一直在试自己选的diet疗法。扫描发现癌变在扩大才动了手术,这段时间癌转移的多少不可知,但肯定越拖转移的越多。
2.手术后没化疗和放疗。Jobs 2005年演讲说这表明病情乐观,不知是哪个庸医给他灌输的。2004年手术是大面积切除,部分胰腺和胃和小肠,胆和胆管都切除,目的是要消除扩散,但不系统化疗和放疗怎么能最大程度减少扩散威胁?哪个外科大夫这么信自己的手艺?
3.2009年换肝,这在扩散性癌治疗是有争议的,因为换肝后压制免疫反应有可能促进别处癌的生长。也有可能当时肝已经不行了没办法。
这种癌正常治疗大多数可活10年以上,Jobs真该到东岸Hopkins或Harvard找个靠谱的大夫。
Jobs’s Unorthodox Treatment
Some of Apple trailblazer Steve Jobs’s cancer treatment choices, from
alternative therapies to a liver tra... 阅读全帖 |
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j**r 发帖数: 7 | 16 Journal of Cardiovascular Disease Research (JCDR) 是个新的,很严肃认真,很有前
途的心血管疾病专业杂志;
(Journal of Cardiovascular Disease Research (JCDR) [ISSN: 0975-3583] is a
double-blind peer-reviewed, open access international circulating
professional journal led by a group of research scientists, vascular disease
experts and cardiologists coming from North America, Asia and Europe etc.)
第一期已经出版,请查看以下网址:
http://www.jcdronline.org
www.jcdronline.com
目前editorial board 的构筑已经完成,现在需要建立review board.希望心血管疾病以
及相关领域的基础和临床研究人 |
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j**r 发帖数: 7 | 17 Journal of Cardiovascular Disease Research (JCDR) [ISSN: 0975-3583] is a
double-blind peer-reviewed, open access international circulating
professional journal led by a group of research scientists, vascular disease
experts and cardiologists coming from North America, Asia and Europe etc.
JCDR covers from basic scientific research to clinical practice dealt with
all areas of cardiovascular diseases. JCDR publishes articles on work at the
molecular, subcellular, cellular, tissular, organic and sy |
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w******e 发帖数: 1187 | 18 Current Pharmaceutical Design
Volume 11 Issue 28
Vascular Homing Peptides with Cell-Penetrating Properties
pp.3655-3660 (6) Authors: E. Ruoslahti, T. Duza, L. Zhang
please email to: l**********[email protected]
Thank you! |
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s******e 发帖数: 841 | 19 Clin Sci (Lond). 2010 Mar 25. [Epub ahead of print]
Tetrahydrobiopterin supplementation reduces atherosclerosis and vascular
inflammation in Apolipoprotein E-knockout mice.
Please send to e********[email protected]
Thanks so much!!!!! |
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S*********e 发帖数: 127 | 20 Promotion of cell spreading and migration by vascular endothelial-protein
tyrosine phosphatase (VE-PTP) in cooperation with integrins.
Mori M, Murata Y, Kotani T, Kusakari S, Ohnishi H, Saito Y, Okazawa H,
Ishizuka T, Mori M, Matozaki T.
J Cell Physiol. 2010 Mar 18. [Epub ahead of print]
a*****[email protected]
Thanks alot |
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S*********e 发帖数: 127 | 21 Endogenous endothelial cell signaling systems maintain vascular stability.
London NR, Whitehead KJ, Li DY.
Angiogenesis. 2009;12(2):149-58. Epub 2009 Jan 27. Review.
and
Transgenic mouse models of angiogenesis and lymphangiogenesis.
Ribatti D.
Int Rev Cell Mol Biol. 2008;266:1-35. Review.
a*****[email protected]
thanks a lot. |
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S*********e 发帖数: 127 | 22 Promotion of cell spreading and migration by vascular endothelial-protein
tyrosine phosphatase (VE-PTP) in cooperation with integrins.
Mori M, Murata Y, Kotani T, Kusakari S, Ohnishi H, Saito Y, Okazawa H,
Ishizuka T, Mori M, Matozaki T.
J Cell Physiol. 2010 Jul;224(1):195-204.
a*****[email protected]
thanks alot. |
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f**d 发帖数: 1952 | 23 Curr Drug Targets. 2010 Apr 26. [Epub ahead of print]
Vascular microRNAs.
Bonauer A, Boon RA, Dimmeler S.
PMID: 20415654 [PubMed - as supplied by publisher]
Please send: p************[email protected]
Thanks a lot. |
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S*********e 发帖数: 127 | 24 The Rac1 Regulator ELMO1 Controls Vascular Morphogenesis in Zebrafish.
Epting D, Wendik B, Bennewitz K, Dietz CT, Driever W, Kroll J.
Circ Res. 2010 May 13. [Epub ahead of print]
a*****[email protected]
thanks alot. |
|
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m*********7 发帖数: 5207 | 26 Is the "缺血" you are talking about due to thrombosis, thromboembolism,
bleeding disorders or abnormal vascular development? |
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c**n 发帖数: 73 | 27 Laser activates endothelium and induces vascular injury.
There are platelets adhesion/aggregation and fibrin deposition.
Furie group from Beth Deacon studied a lot about this particular model.
Check out their papers
Not sure this applies to cerebral vascularture though. |
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e****l 发帖数: 115 | 28 Innate Immunity April 2008 vol. 14 no. 2 63-87
Invited review: Vascular cells contribute to atherosclerosis by cytokine-
and innate-immunity-related inflammatory mechanisms
请发到e********[email protected]
非常感谢!!! |
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x*****a 发帖数: 972 | 29 真就不需要那么多人~~而且人已经很多了。05/06年的时候,很多拿到AP的只做过1年
Post-doc;最
近拿到AP的,都差不多做了2.5年;将来肯定还会延长。
而且几乎没什么应用。几乎所有的器官都有人在做,但是好像就只有skin有比较成熟的
产品。bone,不
还是金属为主啊~至于liver, cardiac, vascular, neural之类,更是远了去了。
只不过说,如果是做modeling之类的,数理背景好,会编程,方便转行;但要转行,直
接转CS就好
了。 |
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t********t 发帖数: 18 | 30 求以下两篇文章的全文。非常感谢~
TRAN CHT, and WELSH DG. the differential hypothesis: a provocative
rationalization of the conducted
vasomotor response. Microcirculation. 17: 226-236
BOEGEHOLD MA. Endothelium-dependent control of vascular tone during early
postnatal and juvenile growth.
Microcirculation. 17: 394-406 |
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s*******w 发帖数: 1879 | 31 不是那一个,是新出来的一个,之前他说要一个做结构的,不过你一说我想起来了,他
们组还真是没有人做nmr的。
但是新出来一个要做vascular biology的,反正我都没洗了,跟其他人说说,大家有兴
趣上啊。 |
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n***w 发帖数: 2405 | 32 Angiotensin and bradykinin: targets for the treatment of vascular and neuro-
glial pathology in diabetic retinopathy.
Please send to n***[email protected]
Thank you!!! |
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C*****h 发帖数: 926 | 33 These findings are wrong.
We examined more than a thousand different GBM slides (stained with all
kinds of important proteins such as PTEN, p53 etc), and found that the
vascularized regions are completely different from the solid tumor regions.
The so-called GBM stem cells are just a piece of crap. |
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s**a 发帖数: 6 | 34 美中药协纽英伦分会
第十三届学术研讨会-癌症药物的创新与未来
时间:2010年12月11日,下午12:30-5:30
地点:麻省理工 斯隆管理学院
Tang Center, Building E51, Room 395
2 Amherst St, Cambridge, MA
美中医药开发协会纽英伦分会(美中药协,Sino-American Pharmaceutical
Professional Association New England Chapter,SAPA-NE)将于2010年 12月11日在
麻省理工学院(Tang center E51-395) 举办一场别开生面的学术研讨会 - 癌症药物的
创新与未来。
本届学术研讨会将由来自Harvard, Brown, Pfizer, Millennium, Novartis的教授和专
家集中讨论癌症创新药物的早期研究和后期运作, 其中包括研究策略,临床测临床测试
, 药物审批, 新药商务化。本届学术研讨会将有助于与会者更好地了解癌症药物者更好
地了解癌症药物研究与开发的发展新趋势和生物医药在中国及全球的... 阅读全帖 |
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b**********t 发帖数: 366 | 35 1.
Journal: Current drug targets
Title: Vascular Endothelial Growth Factor as an Anti-Angiogenic Target for
Cancer Therapy
Author: Niu, etc
Year 2010, Volume 11, Issue 8, Page 1000-1017
Link:
http://www.ncbi.nlm.nih.gov/pubmed/20426765
2.
Journal: Expert opinion on biological therapy
Title: Oligosaccharides as anti-angiogenic agents
Author: Cole, etc
Year 2008, Volume 8, Issue 3, Page 351-362
Link:
http://www.ncbi.nlm.nih.gov/pubmed/18294105
My email: b********[email protected]
Thanks a lot! :) |
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c**n 发帖数: 73 | 36 Proc Natl Acad Sci U S A. 1997 Mar 4;94(5):1973-8.
A genetic analysis of integrin function: Glanzmann thrombasthenia in vitro.
Baker EK, Tozer EC, Pfaff M, Shattil SJ, Loftus JC, Ginsberg MH.
Department of Vascular Biology, Scripps Research Institute, La Jolla, CA 920
37, USA. |
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l*******h 发帖数: 797 | 37 email: l*****[email protected]
thanks!!
http://www.ncbi.nlm.nih.gov/pubmed/20923272
Multiplex cytokine analysis technologies.
Lash GE, Pinto LA.
Reproductive and Vascular Biology Group, Institute of Cellular Medicine,
Newcastle University, Newcastle upon Tyne, NE2 4HH, UK. g******[email protected]
Abstract
Multiplex technologies at both the mRNA and protein level have given
researchers the ability to determine the co-ordinated cellular response to
any given stimuli, in both biological and laboratory-deriv... 阅读全帖 |
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x********u 发帖数: 430 | 38 Purdue Biomaterials, Cell/Tissue Engineering, Transplantation Postdoctoral
Position
Dear Colleagues and Friends, I am searching for a postdoc to start as soon
as possible. Please help me by circulating this posting and please pass on
to any individuals you think might be interested. Thanks! Jenna Rickus 6/
2011. Biomaterials, Cellular & Tissue Engineering, Islet Transplantation
Postdoctoral Position: A postdoctoral position is currently available in the
Bindley Bioscience Center and the Bir... 阅读全帖 |
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c*****6 发帖数: 23 | 39 Tsiara S, Elisaf M, Mikhailidis DP.Influence of smoking on predictors of
vascular disease. Angiology. 2003 Sep-Oct;54(5):507-30.
Sobczak AJ.The effects of tobacco smoke on the homocysteine level--a risk
factor of atherosclerosis. Addict Biol. 2003 Jun;8(2):147-58.
please sent to email: g*********[email protected]. Thanks a lot! |
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s**u 发帖数: 9035 | 40 NEW T32 Training Grant in Cancer Biology at the University of Maryland
We are very pleased to announce that the application for an NIH T32 Training
Grant in Cancer Biology that was submitted in January 2010 was approved for
funding by the National Cancer Institute.
We are funded for a 5 year period, with 4 slots in the first year and 8
slots in the subsequent years. NCI has limitations on the categories of
trainees, with a 1:3 ratio of graduate students to postdoctoral trainees.
At this time, ... 阅读全帖 |
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s**u 发帖数: 9035 | 41 NEW T32 Training Grant in Cancer Biology at the University of Maryland
We are very pleased to announce that the application for an NIH T32 Training
Grant in Cancer Biology that was submitted in January 2010 was approved for
funding by the National Cancer Institute.
We are funded for a 5 year period, with 4 slots in the first year and 8
slots in the subsequent years. NCI has limitations on the categories of
trainees, with a 1:3 ratio of graduate students to postdoctoral trainees.
At this time, ... 阅读全帖 |
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l******n 发帖数: 298 | 42 这个板块能人太多但是技术帖子太少,想学习学习
vascular smooth muscle cell function, differentiation, cell fate, cell
tracking, stem cell differentiation.等等吧,就是平滑肌细胞的领域,血管生物学。
眼看35了,从来没发过什么好文章,请大牛给个提纲我学习学习。发不了nature, JCI啥的也行,10分以下的不考虑了。
最好给个假设的机制,体内体外都能做,我病人样品也都能搞到,老鼠只要jackson lab有的都能买,不差钱!
垃圾,loser,水平差的,没工作的或找不着工作的,不想搞科研的不要跟帖。 |
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c*******7 发帖数: 3763 | 43 干细胞定向分化成为vascular smooth muscle及其分子机制,这个课题怎么样。搞出来的话,一篇nature或者sciences应该问题不大的话。当然,搞不搞得出来,就是另外一回事了。
学。
JCI啥的也行,10分以下的不考虑了。
lab有的都能买,不差钱! |
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n******w 发帖数: 70 | 44 没看后面的讨论,来尝试回答下问题
HYPOXIA和MET是有联系的,HYPOXIA在先,MET在后。可能机理如下
1,Hypoxia-HIF1a-VEGF/VPF-vascular permeability-tumor dissemination;
2,Hypoxia-HIF1a-VEGF-C-peri/intra-tumor infiltration of lymphatic vessel-
tumor dissemination.
3, Hypoxia-met niche-invasive front of tumor-tumor dissemination.
引用就不列了,PUBMED一下就出来。
Dissemination是时时刻刻都存在的,真正能否形成MET,就是一个几率问题。换言之,
DIS越多,MET约有可能形成。 |
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