i******e 发帖数: 171 | 1 in Homo sapiens
Nitzan Mekel-Bobrov,1,2 Sandra L. Gilbert,1 Patrick D. Evans,1,2 Eric J.
Vallender,1,2 Jeffrey R. Anderson,1 Richard R. Hudson,3 Sarah A. Tishko
ff,4 Bruce T. Lahn1*
The gene ASPM (abnormal spindle-like microcephaly associated) is a speci
fic regulator of brain size, and its evolution in the lineage leading to
Homo sapiens was driven by strong positive selection. Here, we show tha
t one genetic variant of ASPM in humans arose merely about 5800 years ag
o and has since swept to hi |
|