M****e
发帖数: 70 | 1 for the offspring from 1st cousin, the possibility getting
homozygous mutations (derived from one of the grandparents)
is only 1/64. and for the reason that uteral or embryonic
lethality increases with homozygous recessive mutations, the
observed genetic disorders could be underestimated. for the
research per se, i have not read the paper. but i would like
to point out that genetic background and subpopulation
structure must be taken account to interpret the data. otherwise,
it could be easily b |
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