f******g
发帖数: 1003 | 1 老板现在正在用chemical screening的方法筛选p21的inhibitor，已经有几个候选的了。
还在申请专利，把的前途说的神乎其神的。
我挺怀疑的，p53的inhibitor很早就有了，但是临床效果不是很明显。 |
h********n
发帖数: 4079 | 2 测试了才知道. 测试要钱, 所以你老板在搞钱.
了。
【在 f******g 的大作中提到】
: 老板现在正在用chemical screening的方法筛选p21的inhibitor，已经有几个候选的了。
: 还在申请专利，把的前途说的神乎其神的。
: 我挺怀疑的，p53的inhibitor很早就有了，但是临床效果不是很明显。
|
h****6
发帖数: 229 | 3 I remember patent for p53 inhibitor applications is owned by an Isreal
company. It was once mentioned that it was very effective against apoptosis.
One application is for heart attack recovery. Heart cells mostly die after
oxygen is available after heart attack. By using p53 inhibitors, it is
possible to prevent heart cells from dying. p21 inhibitors may have similar
effect? |
m******5
发帖数: 1383 | 4 Since oxygen recover would also induce many MAPK pathway, I don't understand
why inhibition of p53 alone could be so effective
apoptosis.
after
similar
【在 h****6 的大作中提到】
: I remember patent for p53 inhibitor applications is owned by an Isreal
: company. It was once mentioned that it was very effective against apoptosis.
: One application is for heart attack recovery. Heart cells mostly die after
: oxygen is available after heart attack. By using p53 inhibitors, it is
: possible to prevent heart cells from dying. p21 inhibitors may have similar
: effect?
|
