g********0
发帖数: 6201 | 1 09/04/2012 Melissa Lee Phillips
Former Harvard postdoc Shane Mayack reaches a settlement with the ORI but
maintains that the duplication of flow cytometry images was an error, not
fabrication.
The U.S. Office of Research Integrity (ORI) has concluded that former
Harvard postdoctoral fellow Shane Mayack engaged in research misconduct
while working in the Joslin Diabetes Center lab of high-profile stem cell
biologist Amy Wagers.
The U.S. Office of Research Integrity (ORI) has concluded that former
Harvard postdoctoral fellow Shane Mayack engaged in research misconduct
while working in the Joslin Diabetes Center lab of high-profile stem cell
biologist Amy Wagers. Source: IdeaConnection
On August 28, the ORI posted a notice to the Federal Register indicating
final action has been taken in the case, which lasted for two years and
involved the retraction of two papers. Mayack has agreed to a voluntary
settlement surrounding the case, although she "neither admits nor denies ORI
's finding of research misconduct."
In August 2010, Wagers told Nature editors she had noticed a problem with
her lab's January 2010 Nature paper "Systemic signals regulate ageing and
rejuvenation of blood stem cell niches," which claimed that age-related
changes in blood stem cells might be reversible (1). Mayack, who was the
first author on that paper, used a flow cytometry plot that appeared
identical to one in a 2008 Blood paper by Mayack and Wagers (2), but it was
used to represent a different experiment with different results.
A retraction notice appeared in Nature in October 2011, but Mayack refused
to sign it and maintained that the results were valid. In the same month,
Wagers also published a statement of concern in Blood for the 2008 paper, "
Osteolineage niche cells initiate hematopoietic stem cell mobilization."
That paper was retracted in late 2011, also without Mayack's signature.
In a 2011 guest post on the blog Retraction Watch, Mayack admitted to
mishandling data—publishing the same plots but with different labels and
results—but said that it was the result of mistakes in data retrieval. "
Errors, not fabrications, were made in assembling figures for these
manuscripts," she wrote. "I am likely the one who made these errors."
However, ORI's final report concludes that Mayack not only duplicated eight
flow cytometry images but also "falsely represented" two images of bone
nodules, by copying them from other authors' unrelated publications.
Mayack maintains that the errors were unintentional, according to a
statement through her lawyer that was posted on Retraction Watch this week:
"These were mistakes in representation and presentation of the data, as
corroborated by ORI’s findings of ‘falsely presented,' and were not due to
fabrication, falsification, or plagiarism of scientific results."
Wagers said in an email that she has "nothing to add to the ORI conclusions,
other than I am glad the matter is concluded."
ORI's notice specifies that the settlement does not constitute admission of
liability by Mayack but notes that she has voluntarily agreed to be
supervised in any federally funded research that she conducts during the
next three years and that she will not serve in any advisory capacity to
federally funded research for that time period as well.
References
Mayack, S. R., J. L. Shadrach, F. S. Kim, and A. J. Wagers. 2010. Systemic
signals regulate ageing and rejuvenation of blood stem cell niches. Nature
463(7280):495-500.
Mayack, S. R., and A. J. Wagers. 2008. Osteolineage niche cells initiate
hematopoietic stem cell mobilization. Blood 112(3):519-531. | c********r
发帖数: 1125 | 2 Amy Wager实验室。。。。
据说在小领域里面名声已经毁了？？ | w********r
发帖数: 1431 | | T****i
发帖数: 15191 | 4 刑不上（有背景的）PI。
薄厚就是苦逼的命。有好处大头是PI的，有坏事大头是薄厚的。
【在 w********r 的大作中提到】
: 在哈佛照样promote,
: 照样发文章
| F*Q
发帖数: 3259 | 5 牛屎堆里的事情？
【在 w********r 的大作中提到】
: 在哈佛照样promote,
: 照样发文章
| F*Q
发帖数: 3259 | 6 我前面说过，学术圈就是奴隶社会和封建社会的结合体。
【在 T****i 的大作中提到】
: 刑不上（有背景的）PI。
: 薄厚就是苦逼的命。有好处大头是PI的，有坏事大头是薄厚的。
| a*********n
发帖数: 2526 | 7 duplication of an image 这种假也太没有技术含量了
稍微勤奋一点的造假的根本就查不出，要不然生物界就不会有那么多似是而非的data了
【在 g********0 的大作中提到】
: 09/04/2012 Melissa Lee Phillips
: Former Harvard postdoc Shane Mayack reaches a settlement with the ORI but
: maintains that the duplication of flow cytometry images was an error, not
: fabrication.
: The U.S. Office of Research Integrity (ORI) has concluded that former
: Harvard postdoctoral fellow Shane Mayack engaged in research misconduct
: while working in the Joslin Diabetes Center lab of high-profile stem cell
: biologist Amy Wagers.
: The U.S. Office of Research Integrity (ORI) has concluded that former
: Harvard postdoctoral fellow Shane Mayack engaged in research misconduct
| f***g
发帖数: 53 | | D*a
发帖数: 6830 | 9 图片盗用PI也可以无罪？？擦，TA名字在paper上面是干嘛用的。
你要说直接从实验伪造结果PI很难控制也就罢了，赤裸裸的搬PI以前签名发表的paper
图片，PI无罪的理由是神马？？？ | T****i
发帖数: 15191 | 10 她上面有人：）
paper
【在 D*a 的大作中提到】
: 图片盗用PI也可以无罪？？擦，TA名字在paper上面是干嘛用的。
: 你要说直接从实验伪造结果PI很难控制也就罢了，赤裸裸的搬PI以前签名发表的paper
: 图片，PI无罪的理由是神马？？？
| H*****e
发帖数: 120 | 11 My previous post:
I always had problem with Amy's work, even her postdoctoral's work in that
big name lab. She is very aggressive which makes me sick. She had no shame
draw big conclusion with a small data and cannot take the 2nd voice. In
these cases, it is obvious that these data fit her big dream. So she even
did not noticed the data itself.
I remember that my mentor even remember every molecular weight marker that I
labelled. As the PI, Amy is responsible for these misconduct for sure. |
|
