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发帖数: 3003 | 2 A total of 90 KEGG pathways were broken down into over 130 million extensive
linear subpathways that considered all multiple gene assignments. Among
these subpathways, 4,644 well-defined subpathways were identified and their
significance evaluated via permutation tests. Subsequently, text-mining
association analysis was performed for the selected significant well-defined
subpathways
From;Pathway-Based Evaluation in Early Onset Colorectal Cancer Suggests
Focal Adhesion and Immunosuppression along with Epithelial-Mesenchymal
Transition
这篇文章说用microarray on colorectal cancer, 大概有5%左右的可以被证实。如果
考虑microarray或者方法的sensitivity, 至少大概10-20%的edge，或者基因之间的连
接可以确认。
但是这个数字有好像太低了，因为KEGGpathway的保守性，一般认为都要大约60%左右的
conservation
不知道大家有没有这方面的经验。 |
