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A Senior Scientist position requiring a Ph.D. degree is available for a
highly motivated and creative candidate with a strong background in human
dendritic cell biology, tumor immunology and immunotherapy to join the
Targeted Therapeutics Discovery Group in the Oncology R&D Unit. The
successful candidate will have an opportunity to establish their own immuno-
oncology research project and expected to collaborate with multiple
immunotherapy program leaders. The ideal applicant will have extensive
experience in investigating mechanisms that regulate anti-tumor immune
responses by activation of innate immunity including Pattern Recognition
Receptor (PRR) signaling or related pathways, and a desire to continue in a
laboratory-focused role. The candidate will have a proven track record of
scientific productivity as evidenced by first author publications in
prominent journals and ability to participate in a highly matrixed and
innovative research environment. The individual will have a leadership role
that participates in strategic discussions, establishes external
collaborations, mentors/manages other scientists and coordinates program
activities. Candidate should be able to translate basic research findings
into novel therapeutic strategies that support clinical drug development.
Responsibilities
• Independently design and execute experiments using cellular and
molecular immunological assays to investigate target biology and therapeutic
mechanisms of action.
• Focused work in tumor and immune cell target identification and
validation.
• Ability to develop novel in vitro assay systems that are predictive
of in vivo biology
• Demonstrate a high level of initiative in troubleshooting
experiments and accurate data analysis.
• Effectively collaborate with other members of the Oncology group and
supporting partner lines.
• Present hypothesis, on-going progress and future plan to project
teams and governance bodies and prepare technical reports
• Conduct research that leads to publication in peer-reviewed journals
and presentation of data at internal and external meetings and conferences.
Education & Training
• Ph.D. degree in Immunology, Cancer Biology, Cell Biology,
Pharmacology or related field with postdoctoral or 0-3 years’ industry
experience plus a solid background in tumor immunology and/or biologic-based
therapeutics.
• Experience in innate immunity and human DC biology will be preferred.
• Strong research experience with a focus on basic immunology
techniques is required, including mammalian cell culture, FACS,
immunofluorescence, ELISA, ELISPOT, cytokine and chemokine detection,
molecular biology techniques and in vivo mouse tumor experience.
• Basic knowledge in antibody, immunotherapy and/or nanoparticle
characterization.
• Excellent communication skills, both written and oral, and highly
organized in terms of goal setting and achieving.
About Pfizer. A career at Pfizer offers opportunity, ownership and impact.
All over the world, Pfizer colleagues work together to positively impact
health for everyone, everywhere. Our colleagues have the opportunity to grow
and develop a career that offers both individual and company success; be
part of an ownership culture that values diversity and where all colleagues
are energized and engaged; and the ability to impact the health and lives of
millions of people. Pfizer, a global leader in the biopharmaceutical
industry, is continuously seeking top talent who are inspired by our purpose
to innovate to bring therapies to patients that significantly improve their
lives.
Visit www.pfizercareers.com and apply to Job ID 1046822 |
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