p**********m
发帖数: 472 | 1 Why I can see baseline seperation using ELSD, while very big tailing peak in
MS. And peaks between two detectors just cannot match.
what should I do next? help... |
D***D
发帖数: 5321 | 2 Because
These are two different detectors.
MS is more sensitive.
in
【在 p**********m 的大作中提到】
: Why I can see baseline seperation using ELSD, while very big tailing peak in
: MS. And peaks between two detectors just cannot match.
: what should I do next? help...
|
s**********8
发帖数: 25265 | 3 no necessarily.
ELSD is a generic detector and MS only applies to ionizable compound. this
is like u r using pda at two different wave length and the profile could be
way different.
【在 D***D 的大作中提到】
: Because
: These are two different detectors.
: MS is more sensitive.
:
: in
|
p**********m
发帖数: 472 | 4 but what i want to know is all of compounds in my sample.
this
be
【在 s**********8 的大作中提到】
: no necessarily.
: ELSD is a generic detector and MS only applies to ionizable compound. this
: is like u r using pda at two different wave length and the profile could be
: way different.
|
d******s
发帖数: 674 | 5 check your extra column volume, where most likely the mismatch and
resolution lost came from.
try to match the tubing size and length for both detectors |
d******s
发帖数: 674 | 6 check your extra column volume, where most likely the mismatch and
resolution lost came from.
try to match the tubing size and length for both detectors |
p**********m
发帖数: 472 | 7 I used the same tube to connect to both detetors. so i do not think that is
problem.
【在 d******s 的大作中提到】
: check your extra column volume, where most likely the mismatch and
: resolution lost came from.
: try to match the tubing size and length for both detectors
|
