c*******n
发帖数: 1648 | 1 http://www.sina.com.cn 2009年12月29日 11:10 中国高新技术产业导报
本报记者 马丰敏报道
爱美的时尚人士对胶原蛋白并不陌生，因为在其被大众知晓之初，就与美丽、健康
关系密切。但
是，直到２０世纪末，世界各大公司还都只能从动物中提取胶原蛋白。普通提纯的动物
胶原蛋白存在
很大的风险，例如变性温度低，３７℃－４０℃的变性温度导致在使用中存放条件比较
苛刻，容易变
性引起功能丧失；动物提纯的胶原蛋白常为酸溶或碱溶，会改变人体本身的酸碱平衡度
，而且动物胶
原蛋白隐含动物本身存在的病毒等病毒隐患。
２０００年，西北大学化工学院教授范代娣以人体自身胶原蛋白的基因片段为来源
，成功研制出
与人体组织同宗同源的胶原蛋白——类人胶原蛋白。就是这项技术打破了胶原蛋白的传
统行业格局，开
创了胶原蛋白的全新时代。现在，范代娣正用胶原蛋白书写自己的美丽人生，开创大众
的美丽事业。
中国第一位生物化工博士
当年高考填报志愿时，喜欢化学的范代娣报考了西北大学化工系。“当时也不知道
化工和化学到底
有什么区别，以为都是学化学的”。于是，懵懵懂懂地开始上课。范代娣说：“不过， |
c********1
发帖数: 517 | 2 上次华东理工那个骗人的核酸解决了没有啊？生工怎么成天出这种骗子？啊？上来解释
一下吧？
（1）
http://www.xys.org/xys/ebooks/others/science/dajia/hesuanyingyang59.txt
2001年2月11日，“全国核酸类物质功能与应用研讨会”在上海召开。主办者是设在 华
东理工大学的中国生物化学与分子生物学会工业生化专业委员会，它是卫生部下属学术
机构。
（2）
http://www.chinanews.com.cn/2001-02-26/26/73693.html |
z*h
发帖数: 773 | 3 范代娣 is a trash. She knew nothing. When I began my graduate research at
ECUST (1994) and asked her a basic technique question in her thesis, she did
not know any know-how. Her thesis was finished by real copy and paste. (For
publication, she cut her original pictures for the pictures). |
f*******c
发帖数: 94 | 4 what sexpression system, and what section of gelatin, purification method?
If purification depends on traditional precipitation, this gelatin is trash
even it is recombinant human gelatin.
As I know, there are not successful gelatin (recombinant) produced in
industrial for several problems:
1) post-translation modification, which cause allerge and other immuno
problem.
2) Gelatin is a big and complex protein, which means no way or too difficult
to express whole gelatin in pichia or E Coli or oth |
c********1
发帖数: 517 | 5 原来还有前科。
对了，这“用胶原蛋白书写美丽人生” 跟以前有个作家说的“用体液来写作”有一比。
did
For
【在 z*h 的大作中提到】
: 范代娣 is a trash. She knew nothing. When I began my graduate research at
: ECUST (1994) and asked her a basic technique question in her thesis, she did
: not know any know-how. Her thesis was finished by real copy and paste. (For
: publication, she cut her original pictures for the pictures).
|
c*******n
发帖数: 1648 | 6 这个我不懂，主要是看到她是第一生化工女博士转的。
trash
difficult
expensive.
【在 f*******c 的大作中提到】
: what sexpression system, and what section of gelatin, purification method?
: If purification depends on traditional precipitation, this gelatin is trash
: even it is recombinant human gelatin.
: As I know, there are not successful gelatin (recombinant) produced in
: industrial for several problems:
: 1) post-translation modification, which cause allerge and other immuno
: problem.
: 2) Gelatin is a big and complex protein, which means no way or too difficult
: to express whole gelatin in pichia or E Coli or oth
|
c*******n
发帖数: 1648 | 7 原来你老也是愤青。
did
For
【在 z*h 的大作中提到】
: 范代娣 is a trash. She knew nothing. When I began my graduate research at
: ECUST (1994) and asked her a basic technique question in her thesis, she did
: not know any know-how. Her thesis was finished by real copy and paste. (For
: publication, she cut her original pictures for the pictures).
|
d********a
发帖数: 3698 | 8 这个不妨碍人家赚大钱，
象胶原蛋白这块可赚大钱了，
女人都买来吃。
did
For
【在 z*h 的大作中提到】
: 范代娣 is a trash. She knew nothing. When I began my graduate research at
: ECUST (1994) and asked her a basic technique question in her thesis, she did
: not know any know-how. Her thesis was finished by real copy and paste. (For
: publication, she cut her original pictures for the pictures).
|
