w***4
发帖数: 302 | 1 妈妈这三年白细胞都比较稳定，一直低于两万。最近白细胞升至两万四，医生建议吃药
降低白血球。药是留可然（苯丁酸氮芥片），一天一片，妈妈服了不良反应挺多的，腰
痛，浑身无力等。服了两周了，白血球降了1000，医生让继续吃。请问这里有同学有关
于慢淋治疗的经验吗，我担心这药也把其他的免疫系统破坏，但不吃又怕白细胞升起来
，请问有同学知道美国这边如何治疗的？
谢谢了！! | h**********a
发帖数: 74 | 2 找个好的国内医院就可以了，如上海瑞金医院，美国这边，问了也解决不了你的实际问
题 | J*********4
发帖数: 1274 | 3 It seems that your mother's disease is indolent
Assume your mother was asymptomatic before the treatment, no weight loss,
low fever, no loss of appetite, no enlargement of lymphonodes, no enlarged
spleen
If her lymphocyte count <30,000/microL, blood lymphocyte doubling time >12
months, hemoglobin ≥13 g/dL, her survival statistics could be similar to
those of an age and sex-matched group.
For 慢淋, even extreme increased lymphocytosis, without symptoms or impaired
bone marrow function such as anemia or low platelet, is NOT an indication
for treatment.
Therefore, she does not need treatment, especially with all the side effects
Bests! | w***4
发帖数: 302 | 4 谢谢你！ 很有帮助！
impaired
【在 J*********4 的大作中提到】
: It seems that your mother's disease is indolent
: Assume your mother was asymptomatic before the treatment, no weight loss,
: low fever, no loss of appetite, no enlargement of lymphonodes, no enlarged
: spleen
: If her lymphocyte count <30,000/microL, blood lymphocyte doubling time >12
: months, hemoglobin ≥13 g/dL, her survival statistics could be similar to
: those of an age and sex-matched group.
: For 慢淋, even extreme increased lymphocytosis, without symptoms or impaired
: bone marrow function such as anemia or low platelet, is NOT an indication
: for treatment.
| m****d
发帖数: 156 | 5 There still might be some reason that the doctor is considering disease
progression, for example, if the white cell baseline was 15k. See below.
Patients with chronic lymphocytic leukemia (chronic lymphoid leukemia, CLL)
do not need to be treated with chemotherapy until they become symptomatic or
display evidence of rapid progression of disease, as characterized by the
following:
Weight loss of more than 10% over 6 months
Extreme fatigue
Fever related to leukemia for longer than 2 weeks
Night sweats for longer than 1 month
Progressive marrow failure (anemia or thrombocytopenia)
Autoimmune anemia or thrombocytopenia not responding to glucocorticoids
Progressive or symptomatic splenomegaly
Massive or symptomatic lymphadenopathy
Progressive lymphocytosis, as defined by an increase of > 50% in 2 months or
a doubling time of less than 6 months
【在 w***4 的大作中提到】
: 妈妈这三年白细胞都比较稳定，一直低于两万。最近白细胞升至两万四，医生建议吃药
: 降低白血球。药是留可然（苯丁酸氮芥片），一天一片，妈妈服了不良反应挺多的，腰
: 痛，浑身无力等。服了两周了，白血球降了1000，医生让继续吃。请问这里有同学有关
: 于慢淋治疗的经验吗，我担心这药也把其他的免疫系统破坏，但不吃又怕白细胞升起来
: ，请问有同学知道美国这边如何治疗的？
: 谢谢了！!
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