b******l 发帖数: 155 | 1 老公从他妈那遗传有糖尿病,我没有。我们家有二女儿一儿子,我的推断如下,不知对否
老公的糖尿病基因在X染色体上,是从他妈来的,他的Y染色体没有糖尿病基因,因为他
爸沒有糖尿病。儿子是我的X染色体加他的Y染色体,所有不会有。女儿们是我的X染色
体(没有糖尿病基因)加他的X染色体(有糖尿病基因),所以两女儿会带有糖尿病基因。
请专家们或懂行的说々,我的推断是否正确 | m**********r 发帖数: 2099 | 2 你说的是孟德尔经典遗传model,不幸的是糖尿病不遵循孟德尔经典模型。
如果是I型糖尿病,有某一种的问题基因在6号染色体短臂上,其他种类的I型糖尿病在2
,14,15,18号染色体上都有变异;
如果是II型糖尿病,至少有36个基因与之有关,大多没有在X染色体上。其中有一种:
Turner Syndrome,病变在X染色体,后代有增加的II型糖尿病危险:但Turner
syndrome有后代的女性都有智力障碍:你婆婆智力如何?身材?
In general, if you are a man with type 1 diabetes, the odds of your child
developing diabetes are 1 in 17.
If you are a woman with type 1 diabetes and your child was born before you
were 25, your child's risk is 1 in 25; if your child was born after you
turned 25, your child's risk is 1 in 100.
Your child's risk is doubled if you developed diabetes before age 11. If
both you and your partner have type 1 diabetes, the risk is between 1 in 10
and 1 in 4. | b******l 发帖数: 155 | 3 老公是ll型。他妈正常智力,个子矮但并不胖
在2
【在 m**********r 的大作中提到】![](/moin_static193/solenoid/img/up.png) : 你说的是孟德尔经典遗传model,不幸的是糖尿病不遵循孟德尔经典模型。 : 如果是I型糖尿病,有某一种的问题基因在6号染色体短臂上,其他种类的I型糖尿病在2 : ,14,15,18号染色体上都有变异; : 如果是II型糖尿病,至少有36个基因与之有关,大多没有在X染色体上。其中有一种: : Turner Syndrome,病变在X染色体,后代有增加的II型糖尿病危险:但Turner : syndrome有后代的女性都有智力障碍:你婆婆智力如何?身材? : In general, if you are a man with type 1 diabetes, the odds of your child : developing diabetes are 1 in 17. : If you are a woman with type 1 diabetes and your child was born before you : were 25, your child's risk is 1 in 25; if your child was born after you
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