T**********e
发帖数: 29576 | 1 Maurice Wilkins把Franklin的DNA X-RAY 背着她给Watson 和 Crick展示,成全这两位
推导出DNA双螺旋结构发表在NATURE, 最后这三个老哥得了诺贝尔奖. 而Franklin得癌
症死掉.
Celebrating Rosalind Franklin: a perfect example of single-minded devotion
to research
Today's Google Doodle honours pioneering British biophysicist and x-ray
crystallographer, Rosalind Franklin
Today is the 93rd anniversary of the birth of British biophysicist Rosalind
Franklin, who was a pioneering x-ray crystallographer who is being honoured
today with a special Google Doodle.
Nearly everyone who has heard about Dr Franklin knows that her work was
critical to elucidating the structure and function of DNA -- a discovery
that was recognised by the 1962 Nobel Prize in Physiology or Medicine four
years after her tragic death from ovarian cancer. (Dr Franklin was not
nominated for this award; Nobel Prizes are not awarded posthumously.)
Dr Franklin was an x-ray crystallographer. To do her work, she would purify
a molecule, such as DNA, grow it into crystals and bombard the crystal with
x-rays. After photographing the x-ray diffraction pattern created by
collisions with atoms within the crystal (see right), Dr Franklin then could
directly determine the structure of the molecule.
Dr Franklin's work, particularly "Photo 51" (pictured, right; by Raymond
Gosling), was critical for correctly determining the structure and function
of DNA. According to my sources, Maurice Wilkins, who was Dr Franklin's
supervisor at King's College London, shared several of her images, including
"Photo 51", with James Watson without her knowledge or consent. Up until
the time when they saw this particular image, Watson and his colleague,
Francis Crick, had erroneously postulated that the DNA "backbone" was on the
inside of the molecule and the nucleic acid "bases" pointed outwards, like
the teeth of a comb. This image pointed out their error in logic so they
quickly revised their hypothesis and published it, which then led to them
being awarded the Nobel Prize a few years later.
http://www.guardian.co.uk/science/grrlscientist/2013/jul/25/ros | T**********e
发帖数: 29576 | 2 google把她上在首页, Rosalind Franklin这些年大有成为早期职业妇女受职场男人合
谋阴险迫害典型的趋势. | h******1
发帖数: 16295 | 3 俺问Watson：当年你哥俩用了多长时间琢磨出双螺旋结构的？
他说：大约一小时。 | T**********e
发帖数: 29576 | 4
何时见过他老?
【在 h******1 的大作中提到】
: 俺问Watson：当年你哥俩用了多长时间琢磨出双螺旋结构的？
: 他说：大约一小时。
| s**i
发帖数: 4448 | 5 这个就难说了，很明显，那时候Rosalind和她PI没想出来DNA结构。
那哥俩也技术上没做错什么，给他们看了，也就相当于data went public,除非PI当时
强调是confidential information。 | s**i
发帖数: 4448 | | h******1
发帖数: 16295 | 7 那时候他还不这么老。
对了，他当时对中国的遗传学，也就是计划生育深恶痛绝。后来我很惊异地发现他去中
国做报告去了。看来有钱能使鬼推磨，老鬼也不例外。
【在 T**********e 的大作中提到】
:
: 何时见过他老?
| T**********e
发帖数: 29576 | 8
他老从DNA之后就没搞过什么科研吧, 主要是当官了.
【在 h******1 的大作中提到】
: 那时候他还不这么老。
: 对了，他当时对中国的遗传学，也就是计划生育深恶痛绝。后来我很惊异地发现他去中
: 国做报告去了。看来有钱能使鬼推磨，老鬼也不例外。
| h******1
发帖数: 16295 | 9 对了，我问他了一个重要的问题：21世纪是什么世纪？
他说：当然是生物学的世纪，确切地说，是神经科学的世纪。
我问何以见得？
他说：当然，人们会造出更好的伟哥。
【在 T**********e 的大作中提到】
:
: 他老从DNA之后就没搞过什么科研吧, 主要是当官了.
| T**********e
发帖数: 29576 | 10
伟哥提神?
【在 h******1 的大作中提到】
: 对了，我问他了一个重要的问题：21世纪是什么世纪？
: 他说：当然是生物学的世纪，确切地说，是神经科学的世纪。
: 我问何以见得？
: 他说：当然，人们会造出更好的伟哥。
|
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