I******t
发帖数: 1619 | | I******t
发帖数: 1619 | | w********g
发帖数: 447 | 3 俺做，但是工业界好像不怎么care这个东西，比DMPK肯定差多了
【在 I******t 的大作中提到】
: 没有一个人做啊？有那么冷吗？郁闷
| s**********r
发帖数: 330 | 4 Up and coming, but more difficult than proteomics, which is already
struggling. At least there are protein databases available, but for
metabolites such resources are very limited. Even if you have a mass
measurement with high accuracy, itself alone is often not enough for
identification. Sometimes for unknown metabolites of low abundance, I can't
even distinguish real signal from noise. | I******t
发帖数: 1619 | 5 NMR就可以准确定性啊，定量差点，灵敏度差，不过基本MS的metabolomics的数据库也
有啊，好几个啊，而且有NIST library可以来search GCMS的数据啊，对于一些比较低
浓度的化合物来说，确实是比较难，不过现在的分析手段，越来越好了，LECO的那个
GCXGC MS好像很强大啊，软件也很棒哦
't
【在 s**********r 的大作中提到】
: Up and coming, but more difficult than proteomics, which is already
: struggling. At least there are protein databases available, but for
: metabolites such resources are very limited. Even if you have a mass
: measurement with high accuracy, itself alone is often not enough for
: identification. Sometimes for unknown metabolites of low abundance, I can't
: even distinguish real signal from noise.
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