s****9 发帖数: 932 | 1 不知道楼上的两个人怎么回答你的问题的?你的问题这么笼统。
你是想overexpress BM-derived dendritic cell还是splenic dendritic cells,还
是tissue dendritic cells?Human的还是老鼠的?各种感染都有不同的protocol?In
vivo还是In vitro?有的retrovirus效果就非常好,有的lentivirus也很难。
楼上的回复的就随口说说,也不attach文献什么的,不知道楼主获得有用信息没有?
哎。。。。 |
|
c**********a 发帖数: 6 | 2 Dendritic polymers can be used as effective decoloring agent.
Dendrimers can effectively remove triarylmethane dyes. Its advantages are: (
1) the higher the pH value, the better the decoloring effect, the highest
decolorization rate is 99.8% (2) less dosage, achieve good results with
dosage concentration of 33.3mg / L (3) dendrimer can be reused, and to
maintain a high decolorization activity; (4) Dendrimer has a good treatment
effect for different components of the sewage (5) a low concentratio... 阅读全帖 |
|
c**a 发帖数: 94 | 3 dendritic spines retract or collapse之后,它的PSD structure咂整了啊, 落回
dendrite上之后是解散
了吗, 要是没有解散, 那spine还可能从同一个地方再重新长起来吗.
能给篇reference吗,谢谢 |
|
o*****n 发帖数: 445 | 4 现在在e coli里表达一个蛋白,这个蛋白序列里有cystein。我想知道蛋白纯化时需不
需要加入dtt.
蛋白是neuron dendrites里的一个蛋白,不知道dendrite里是不是reducing
environment?
谢谢。 |
|
f*******n 发帖数: 1 | 5 Steinman实验室的Science文章。非常老的一个抗原,很有意思的发现,非常新的认识
。这一期的Cell上有Akiko Iwasaki写的一篇prereview,记得这个版面有人评论过这个
日本mm是否美女来着,显然她的研究领域已经不仅仅是mucousal immunity了,应该还
会保持上升的。
http://www.sciencemag.org/cgi/content/abstract/315/5808/107
Science 5 January 2007:
Vol. 315. no. 5808, pp. 107 - 111
DOI: 10.1126/science.1136080
Prev | Table of Contents | Next
Reports
Differential Antigen Processing by Dendritic Cell Subsets in Vivo
Diana Dudziak,1 Alice O. Kamphorst,1 Gordon F. Heidkamp,1 Veit R. Buchholz,1
Christine Trump |
|
n********k 发帖数: 2818 | 6 Could any friends recommend nice and simply ways to look at mature neuron
dendritic morphology in hippocampus (CA regions and DG as well). my Cre is
so bright and GFP is so weak, hard to tell...not sure whether my sections
still can go for Golgi staining since we perfused with PFA and then sucrose
and then section at 30um...I am thinking to go with calbindin... |
|
s****9 发帖数: 932 | 7 I do not know. I assume that DC is very good at internalizing antigens and
bounded Ig can be easily internalized before successful ADCC occurs.
Similarly, I never see any reference depleting macrophages in vivo using mAb.
In addition, if CD11c-DTR cannot be used and macrophages play little role in
your system, you might consider clodronate liposome. High dose of CLL
depletes macrophages and most dendritic cells. |
|
s*****y 发帖数: 55 | 8 刚好看过这篇很有意思的文章:Effective collaboration between marginal
metallophilic macrophages and CD8+ dendritic cells in the generation of
cytotoxic T cells
用的就是楼上说的clodronate liposome。我用这东西除过macrophage,效果不错 |
|
k****n 发帖数: 158 | 9 各位同修,
请赐一个梯度离心分离dendritic cells (mouse)的 protocol, 给了文献或者公司的链
接就可,
谢谢 |
|
s****9 发帖数: 932 | 10 不知道版上哪个牛人实验室有D1 dendritic cell line?或者知道哪个美国实验室有?
查到的文献都是欧洲的,在ATCC也没有查得到。
只需要提供信息就好,我可以让我老板发信(提供Fedex account)索取。
有用信息,给5个热包子以示热情感谢。 |
|
f**d 发帖数: 768 | 11 这是一本计算神经科学的优秀著作,全文拷贝这里(图和公式缺),有兴趣的同学可以
阅读
如需要,我可以分享PDF文件(--仅供个人学习,无商业用途)
From Computer to Brain
William W. Lytton
From Computer to Brain
Foundations of Computational Neuroscience
Springer
William W. Lytton, M.D.
Associate Professor, State University of New York, Downstato, Brooklyn, NY
Visiting Associate Professor, University of Wisconsin, Madison
Visiting Associate Professor, Polytechnic University, Brooklyn, NY
Staff Neurologist., Kings County Hospital, Brooklyn, NY
In From Computer to Brain: ... 阅读全帖 |
|
发帖数: 1 | 12
Download pdf published by SfN (Chapter from 'The History of Neuroscience in
Autobiography, Volume 8' edited by Larry R. Squire)
Yuh-Nung Jan's CV
Lily Jan's CV
Yuh-Nung Jan and Lily Jan
Birth
Family History and Growing Up
National Taiwan University
The Hiking Trip to Shitou in the Spring of 1967
Graduate School Application
Graduate Study at Caltech (1968锟974)
Seymour Benzer Lab (1974锟977)
Steve Kuffler锟絪 Lab at H... 阅读全帖 |
|
h******y 发帖数: 1374 | 13 The Nobel Prize in Physiology or Medicine 2011
shall be divided, with one half jointly to
Bruce A. Beutler and Jules A. Hoffmann
for their discoveries concerning the activation of innate immunity
and the other half to
Ralph M. Steinman
for his discovery of the dendritic cell and its role in adaptive immunity
Summary
This year's Nobel Laureates have revolutionized our understanding of the
immune system by discovering key principles for its activation.
Scientists have long been searching for the g... 阅读全帖 |
|
a****y 发帖数: 1035 | 14 【 以下文字转载自 Biology 讨论区 】
发信人: hellowhy (夹死do it), 信区: Biology
标 题: 2011 Nobel Prize in Physiology or Medicine
发信站: BBS 未名空间站 (Mon Oct 3 08:44:48 2011, 美东)
The Nobel Prize in Physiology or Medicine 2011
shall be divided, with one half jointly to
Bruce A. Beutler and Jules A. Hoffmann
for their discoveries concerning the activation of innate immunity
and the other half to
Ralph M. Steinman
for his discovery of the dendritic cell and its role in adaptive immunity
Summary
This year's Nobel Laureate... 阅读全帖 |
|
|
A********e 发帖数: 354 | 16 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时,深深的鄙视一下自己的无聊行径!!
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
|
p*******g 发帖数: 2976 | 17 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时,深深的鄙视一下自己的无聊行径!!
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
|
O***n 发帖数: 13127 | 18 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时,深深的鄙视一下自己的无聊行径!!
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
|
a********k 发帖数: 2273 | 19 花了一个小时,深深的鄙视一下自己的无聊行径!!
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branches in lamellipodia. Cell. 2008 Sep
5;134(5):828-42. PubMed PMID: 18775315; PubMed Central PMCID: PMC2570342.
Cai L, Makhov AM, Bear JE. F-actin... 阅读全帖 |
|
p*******g 发帖数: 2976 | 20 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时,深深的鄙视一下自己的无聊行径!!
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
|
l***d 发帖数: 1828 | 21 http://www.bbc.co.uk/news/health-15155642
Canadian scientist Ralph Steinman will keep his Nobel prize for medicine,
the Nobel Foundation has said, after his death on Friday threw it into doubt.
The rules state "work by a person since deceased shall not be considered".
But the foundation said it was unaware of Prof Steinman's death from
pancreatic cancer and that the award had been made "in good faith".
Prof Steinman was announced the joint winner on Monday, along with Prof
Bruce Beutler and Prof... 阅读全帖 |
|
f**d 发帖数: 768 | 22 http://online.itp.ucsb.edu/online/neuro10/
有兴趣的同学可以观看其中视频cam链接,效果很清晰,
学习的同时也可以非常好地练习英语听力
KITP Program: Emerging Techniques in Neuroscience (Sep 20 - Nov 12,
2010) Coordinators: Adrienne Fairhall, David Kleinfeld, Fred Wolf
Speakers: Please see us about file upload for your slides.
会议内容涉及实验和计算神经科学的比较广泛的课题
Time
Speaker
Title
9/20, 10:15 a.m.
All
Greeting & Salutations from Adrienne, David & Fred[Podcast][Aud][Cam]
9/20, 10:30 a.m.
John Hopfield
Princeton, IAS
How Have Experiment and Theory Informe... 阅读全帖 |
|
m****s 发帖数: 18160 | 23 【 以下文字转载自 Biology 讨论区 】
发信人: eefil (eefil), 信区: Biology
标 题: Job opening: QC Scientist (Beijing Yizhuang)
关键字: job,opening,bejing
发信站: BBS 未名空间站 (Tue Jan 22 21:32:10 2013, 美东)
Company Introduction
SOTIO is a European biotechnology company developing new therapies based on
activated dendritic cells, focusing on the treatment of cancer and
autoimmune diseases. Our mission is to develop new medical therapies using
our proprietary cell-based technologies to treat highly unmet medical
conditions usi... 阅读全帖 |
|
e***l 发帖数: 33 | 24 Company Introduction
SOTIO is a European biotechnology company developing new therapies based on
activated dendritic cells, focusing on the treatment of cancer and
autoimmune diseases. Our mission is to develop new medical therapies using
our proprietary cell-based technologies to treat highly unmet medical
conditions using our immunotherapy platform. Sotio (Beijing), a fast growing
subsidiary focusing on China market, is looking for talented, motivated,
dynamic employees to join its internation... 阅读全帖 |
|
k*****1 发帖数: 454 | 25 刚刚找到一篇文章, 两个电生理的专家 Lisman 和 Spruston 的, 有兴趣的话可以看
一下
Questions about STDP as a General Model of Synaptic Plasticity
John Lisman and Nelson Spruston
According to spike-timing-dependent plasticity (STDP), the timing of the Na+
spike relative to the EPSP determines whether LTP or LTD will occur. Here,
we review our reservations about STDP. Most investigations of this process
have been done under conditions in which the spike is evoked by postsynaptic
current injection. Under more realistic condition... 阅读全帖 |
|
s**********x 发帖数: 4593 | 26 报讯2007年9月2日至9月6日,加州理工大学(Caltech)Erik Winfree博士实验室特邀
我中心博士生钱璐璐前往加州理工进行了数天的学术访问,并承担全部费用。在访问期
间,钱璐璐介绍了Bio-X中心的科学研究情况;并进行了学术演讲,重点介绍了本中心
DNA计算组关于DNA折纸术方面的研究成果,获得了普遍赞誉。Winfree博士是DNA计算领
域最重要的科学家之一,该组的资深科学家PaulRothe-mund是DNA折纸术的发明者,他
们与Bio-X中心科学家之间有着广泛的共同研究兴趣。钱璐璐借此机会与同行们就双方
过去所取得的研究成果进行了深入的探讨,并展望了未来领域的发展情景。此外,南加
州大学的LenAdleman(被国际誉为DNA计算机之父)专程会见了钱璐璐并进行了愉快的
交流。
10月16日,应我室原子与分子科学研究部陈艳霞教授的邀请,加州理工大学Erik
Winfree副教授和钱璐璐博士前来我室进行学术交流与访问,并为我室师生献上“
Dendritic Synthetic Chemistry:Challenges and Rewards和Dendritic
Su... 阅读全帖 |
|
F***Q 发帖数: 6599 | 27
what matters is the charge/discharge cycles, because Li-ion forms dendrites
on the anode during the charging/discharging process
http://newscenter.lbl.gov/2013/12/17/roots-of-the-lithium-batte
this has nothing to do with shelf-life. mileage is a perfect measure of
charge/discharge cycles.
also, almost all EV manufacturers offer 8 yr/100k mile warranty for the
battery pack, and guarantee at least 70%-80% capacity. in reality,
many EV makers play on the safe side, and use a shallow Depth of
Charg... 阅读全帖 |
|
l*****g 发帖数: 547 | 28 母细胞性浆细胞样树突细胞肿瘤二例并文献复习
Blastic plasmacytoid dendritic cell neoplasm: two cases report and review of
literatures
提高对母细胞性浆细胞样树突细胞肿瘤(blastie plasmacytoid dendritic cell
neoplasm,BPDC)的认识.方法 报道2例BPDC患者,并复习文献总结该病临床及实验窒检杏
特点,介绍肿瘤细胞起源的最新进展.结果 2例患者均以皮肤结节起病,肿瘤细胞表达CD4
和CD56,不表达髓系、T细胞以及B细胞特异性标志.对初始治疗敏感,但迅速复发,病程分
别为26、11个月.结论 BPDC是少见的淋巴瘤亚型,具有独特的免疫表型,病程呈侵袭性,
预后差.近期研究表明肿瘤细胞起源于浆细胞样树突细胞前体细胞.
作 者:安刚 齐军元 邹德慧 赵耀中 陈辉树 邱录贵 AN Gang QI Jun-yuan ZOU De-
hui ZHAO Yao-zhong CHEN Hui-shu QIU Lu-gui
作者单位:中国医学科学院北京协和医学院血液学研 |
|
l*h 发帖数: 4124 | 29 let me clarify a little bit.
Letterer-Siwe was first described close to a hundred years ago. the use of "
Letterer-Siwe" has changed several times over the time. at this time, most
physicians use it to describe a certain clinical presentation of Langerhans
cell histiocytosis (ie. infantile multifocal multisystem type ). but some
use it as a synonym of Langerhans cell histiocytosis.
first, the diagnosis of Langerhans cell histiocytosis must be confirmed.
assuming it is the correct diagnosis,
seco... 阅读全帖 |
|
c******r 发帖数: 3778 | 30 你说的跟他们说的根本不是一回事。
国内这个叫做生物治理,免疫治疗。就是提取周围血,培养其中的dendritic cells。
通过IL的刺激增强其抗原递呈能力。然后回输,希望能够增强对肿瘤抗原的递呈从而激
活自身免疫系统,消灭肿瘤。
问题是dendritic cell即使增强了抗原递呈能力也不一定能够递呈有效的肿瘤抗原,即
使递呈了有效的肿瘤抗原也不一定能够激活免疫识别,即使激活了免疫系统也不能保证
肿瘤细胞永远表达这些抗原。结果就是在临床上,效果非常有限。不能说绝对没有,但
是无法确定是否有效,无法预期哪些人有效。导致医院广告产生的患者预期与临床结果
不符。
直肠癌肝转移,至少在中国治疗意义不大。一般医院也不愿意接受这样的病人。并非完
全不值得治疗,但是患者要把期望降下来。大概时间不超过一年。积极治疗也不会有很
大差别。当然这还要看具体的肿瘤性质,患者状况,介入手段,治疗选择,等等。 |
|
m*****i 发帖数: 4342 | 31 Steinman managed to extend his own life 3.5 years beyond the few months that
most pancreatic patients live by his own research. (Steve Jobs had a
different form of pancreatic cancer).
"Dr. Steinman was diagnosed with pancreatic cancer four years ago, and his
life was extended using a dendritic-cell based immunotherapy of his own
design, according to Rockefeller University."
Dr. Steinman, born in 1943 in Montreal, co-discovered in 1973 a new cell
type he called the dendritic cell. He showed that ... 阅读全帖 |
|
c**********a 发帖数: 6 | 32 Dendrimer-based dispersant have great performance.
To lead the solid matter such as pigment into a liquid medium, a high
mechanical strength is necessary, traditionally, use dispersants to deal
these substances, mainly related surfactants. In addition, the dispersed
solid material tends to re-coalescence and flocculate the entire system,
current disadvantage of the products is that viscosity is limited to lower
with highly filled colored dispersion system. Dendritic dispersant has
superior dispe... 阅读全帖 |
|
H********g 发帖数: 43926 | 33 Atomic structure of sensitive battery materials and interfaces revealed by
cryo–electron microscopy
。。。 yi cui
Frozen in time
The electrochemical processes occurring in a battery are highly dynamic. To
understand the complexities of the charge and discharge cycles, you need to
be able to watch the processes in situ or to freeze the battery rapidly for
ex situ analysis. Li et al. applied cryo–electron microscopy techniques
commonly used for studying biological samples to examine batteries. They
i... 阅读全帖 |
|
K**********e 发帖数: 188 | 34 这个貌似本版没人转载?
===========================================
从水滴到彩虹——2010年中科院神经科学研究所年会蒲慕明所长报告~依旧由方琪同学
根据录音整理,
欢迎转载分享~^^
来源: 方琪的日志
这应该是这次年会唯一一份文字记录,也就是说N年后有同学查的话,也只能找到这篇
文章,算是为神
经科学的发展做出小小的一份贡献。考虑到年会中所有的报告都是未发表的结果,因此
禁止摄像、摄影
和录音,不过我想蒲慕明所长的讲话还是值得冒偷偷录音的风险的。其他一些有趣的信
息我稍后几天
会整理出来。蒲先生还是很擅长说冷笑话的。欢迎转载分享,让更多的同学感受到科学
的魅力~^^
2010年中科院神经科学研究所年会蒲慕明所长报告
2010 12月28日 16:30
不会拖太长,今年这报告做完要赶飞机……首先我想先说说这次年会,非常不寻常的年
会,这次来参加的
外来单位是最多的,往年我们最多只请一个单位,今年我们请了三个单位[中科院生物
物理所、复旦大
学脑科学研究院、浙江大学医学部],每一个组的发言机会少一些,但是呢我们题目的
内容更丰富,交
流有更多... 阅读全帖 |
|
n***3 发帖数: 663 | 35 1. Nat Biotechnol. 2004 Dec;22(12):1546-53. Epub 2004 Nov 21.
Silencing of SOCS1 enhances antigen presentation by dendritic cells and
antigen-specific anti-tumor immunity.
Shen L, Evel-Kabler K, Strube R, Chen SY.
2. Nat Biotechnol. 2006 Dec;24(12):1581-90. Epub 2006 Dec 3.
An essential role for Akt1 in dendritic cell function and tumor
immunotherapy.
Park D, Lapteva N, Seethammagari M, Slawin KM, Spencer DM.
3. Nat Biotechnol. 2008 May;26(5):571-7. Epub 2008 Apr 20.
Single-round infectious part... 阅读全帖 |
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a********k 发帖数: 2273 | 36 搜了一下,觉得院士还行嘛,很多人引用都还不错。
科学院院士饶子和,工程院院士曹雪涛,科学院院士常文瑞,科学院院士杨焕明,科学
院院士张启发
饶同学:The crystal structures of severe acute respiratory syndrome virus
main protease and its complex with an inhibitor,引用297
曹同学:Splenic stroma drives mature dendritic cells to differentiate into
regulatory dendritic cells,引用222
常同学:Crystal structure of spinach major light-harvesting complex at 2. 72
resolution,引用617
杨同学有很多,不过估计有人不齿他:A draft sequence of the rice genome (Oryza
sativa L. ssp. indica)引
用1953
张同学也有很多,挑一个小paper吧:Pat... 阅读全帖 |
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s******r 发帖数: 2876 | 37 那就是说饶毅还没有到一骑绝尘的地步,
搜了一下,觉得院士还行嘛,很多人引用都还不错。
科学院院士饶子和,工程院院士曹雪涛,科学院院士常文瑞,科学院院士杨焕明,科学
院院士张启发
饶同学:The crystal structures of severe acute respiratory syndrome virus
main protease and its complex with an inhibitor,引用297
曹同学:Splenic stroma drives mature dendritic cells to differentiate into
regulatory dendritic cells,引用222
常同学:Crystal structure of spinach major light-harvesting complex at 2. 72
resolution,引用617
杨同学有很多,不过估计有人不齿他:A draft sequence of the rice genome (Oryza
sativa L. ssp. indica)引
用1953
张同... 阅读全帖 |
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h******y 发帖数: 1374 | 38 新浪科技讯 北京时间9月21日晚间消息,汤森路透9月21日公布了年度汤森路透引文桂
冠得主名单,以预测将于10月公布的诺贝尔奖科学和经济学类得主,名单上的科研人员
将有可能成为各项诺贝尔奖的有力争夺者。
每年,汤森路透都会利用其研究解决方案Web of Knowledge™中的数据,根
据诺贝尔奖的生理或医学、物理、化学与经济分类,使用定量数据来分析和预测最有影
响力的研究人员。根据其发表的研究成果的总被引频次,这些高影响力研究人员被授予
汤森路透引文桂冠得主(Citation Laureates)称号,预示着他们可能成为今年或不久将
来的诺贝尔奖得主。
汤森路透是唯一采用定量数据预测年度诺贝尔奖得主的机构,自2002年起,共有21
位引文桂冠奖得主赢得诺贝尔奖。
汤森路透研究服务引文分析师David Pendlebury说:“在科学社群里,若经过分析
和计算,引文可以作为另一种形式的同行评审。一位科学家发表研究成果的被引用次数
越多,这位学者在其同行之中、从学术角度的受敬重程度越高,而这可以作为如诺贝尔
奖这类奖项的预测指标。汤森路透引文桂冠奖是通过成熟完善的方法评估引用... 阅读全帖 |
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l***d 发帖数: 1828 | 39 生理学或医学
Brian J. Druker 美国奥勒冈州波特兰市奥勒冈健康暨科学大学 (Oregon Health
Science University)医学教授、JELD-WEN血癌研究教授及奈特癌症研究所(OHSU
Knight Cancer Institute)主任、同时也是霍尔休斯医学研究所(Howard Hughes
Medical Institute)研究人员
Nicholas B. Lydon 美国怀俄明州杰克森洞(Jackson Hole, WY)Granite ***a, LLC
创办人;美国加州圣地牙哥AnaptysBio共同创办人兼总监;及美国麻州剑桥Blueprint
Medicines共同创办人兼总监
Charles L. Sawyers 美国纽约州纽约市Memorial Sloan-Kettering癌症中心人类肿
瘤学及病因Marie-Josee and Henry R. Kravis教授、同时也是霍尔休斯医学研究所(
Howard Hughes Medical Institute)研究人员
获奖成就:他们发展出***性慢性骨髓性白血病治疗药物im... 阅读全帖 |
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z*t 发帖数: 863 | 40 Beutler得奖,Medzhitov会不会有意见?
http://www.sciencedirect.com/science/article/pii/S1074761309002
Ruslan Medzhitov
This year marks the 20th anniversary of a publication (Janeway, 1989) that
in many ways revolutionized our understanding of the immune system. As part
of the proceedings of the Cold Spring Harbor Symposium on Immune Recognition
, the paper authored by the late Charles A. Janeway, Jr. was not a standard
peer-reviewed publication. In fact, Charlie used to refer to it as “the
best paper I've ... 阅读全帖 |
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l**********1 发帖数: 5204 | 41 Sure
BTW,
试下转进西欧大陆 的职位 也未尝不可
for example:
France:
Post-doctoral fellowship 2-3
Lille France
(February, 9th 2012)
//u1019.lille.inserm.fr/position-available/post-doctoral-fellowship/?lang=en
Lionel POULIN CR
Dendritic Cells in Infection and Immunity Laboratory (DCIIL)
Our objectives aim at investigating the roles play by human and mouse dendritic cells (DC) subsets in
infection and immunity. The laboratory name, DCIIL, has been chosen to really underline that our Institute
philosophy, the resolu... 阅读全帖 |
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s*********t 发帖数: 600 | 42 没人转这个咩?老Poo的2012年新年报告
版主给m下,再给一个包子吧:)
——————————————————————
科学追求的事实和谬论——2011中科院神经所年会蒲慕明所长报告
方琪
今年的神经所年会蒲慕明所长的报告继续由我根据录音整理,不知是不是独家,在年末
愿与有志于科学的同学们共勉~^^
科学追求的事实和谬论
Facts and Fallacies in Science
Mu-ming Poo
2011.12.29 16:30-17:15
好,我们今年年会非常热烈,大家都看到了,我们年年有进展,今年很多进展的报告大
家都觉得很兴奋,我想先讲今年所里几件大事吧,第一件大事是现在所里的领导增加了
鲜血,大家可能还不知道,王燕老师是我们所里正式的学术副所长,舒友生老师是我们
的党委副书记[在座一同学说道:“舒老师今天实验室来了新样品,估计在做实验今天
……”],还有王佐仁老师是所长助理,我们最近又来了几个新的师长,最新的是昨天
到的张翼凤老师,Harvard博士后,UCSD的PhD,有些同学听过她的报告,有些同学没有
听过,可以给她安排一场,晚上的seminar.
下面为大家讲... 阅读全帖 |
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p*****m 发帖数: 7030 | 43 不喜欢
没人转这个咩?老Poo的2012年新年报告
版主给m下,再给一个包子吧:)
——————————————————————
科学追求的事实和谬论——2011中科院神经所年会蒲慕明所长报告
方琪
今年的神经所年会蒲慕明所长的报告继续由我根据录音整理,不知是不是独家,在年末
愿与有志于科学的同学们共勉~^^
科学追求的事实和谬论
Facts and Fallacies in Science
Mu-ming Poo
2011.12.29 16:30-17:15
好,我们今年年会非常热烈,大家都看到了,我们年年有进展,今年很多进展的报告大
家都觉得很兴奋,我想先讲今年所里几件大事吧,第一件大事是现在所里的领导增加了
鲜血,大家可能还不知道,王燕老师是我们所里正式的学术副所长,舒友生老师是我们
的党委副书记[在座一同学说道:“舒老师今天实验室来了新样品,估计在做实验今天
……”],还有王佐仁老师是所长助理,我们最近又来了几个新的师长,最新的是昨天
到的张翼凤老师,Harvard博士后,UCSD的PhD,有些同学听过她的报告,有些同学没有
听过,可以给她安排一场,晚上的seminar.
下... 阅读全帖 |
|
k****n 发帖数: 158 | 44 title:
Mechanisms of cross presentation in dendritic cells and the dendritic-like
cell line, KG-1
Author:
Anne Lenore Ackerman
谢谢 |
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l**********1 发帖数: 5204 | 45 it a book,
i can not download full book here.
Mechanisms of cross presentation in dendritic cells and the dendritic-like
cell line, KG-1
by Ackerman, Anne Lenore, Ph.D., YALE UNIVERSITY, 2008,
273 pages |
|
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p*****c 发帖数: 20445 | 47 Marc R. Freeman, Ph.D.
HHMI Early Career Scientist
University of Massachusetts Medical School
Neurons hog the attention, but our brains couldn’t operate without the
unassuming neural cells called glia. Marc Freeman is working to bring these
overlooked cells—which represent about 60 percent of brain cells—their
share of credit.
Freeman has been dissecting the role of glia in brain development, function,
and healing after injury, when glia hurry to the damaged area and devour
cellular debris to al... 阅读全帖 |
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e*******r 发帖数: 275 | 48 请问版上哪位可不可以refer我一些审稿机会,最近心力交瘁,急需申请绿卡。先谢过
了。
方向大致是dendritic spines, dendritic spine morphology,actin, cytoskeleton,
receptor tyrosine kinase, opioid receptors, GPCR, functional selectivity,
arrestin recruitment. etc.
a**********[email protected] |
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T****i 发帖数: 15191 | 49 可以加DMSO,和一般细胞系一样。不过影响dendritic structure, 尤其dendritic
spine。 |
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d****h 发帖数: 46 | 50 For rat neuron
GABRA1: (Neuron. 1989 Dec;3(6):745-53.A novel alpha subunit in rat brain
GABAA receptors.Khrestchatisky M, MacLennan AJ, Chiang MY, Xu WT, Jackson MB
, Brecha N, Sternini C, Olsen RW, Tobin AJ.)
GABBR2:similar to GABRA1, highly neuron-specific
MAP2:(A Harada, J Teng, Y Takei, K Oguchi, N Hirokawa
MAP2 is required for dendrite elongation, PKA anchoring in dendrites, and
proper PKA signal transduction J Cell Biol, 158 (2002), pp. 541–549)
Tuj1: (J Neurobiol. 1995 May;27(1):26-43.Div... 阅读全帖 |
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