a*t
发帖数: 2596 | 1 我考，太纨绔了，太过分了
自己的setup啊，用过的effect pedal 也拿出来晒晒吧！！期待xchain奔他的器材！
就买了这个，比较便宜不过感觉好像没太大分别，而且这个
用的空间比较小，所以就用了
的effect都很好,特别是Undulator。本来想买Electro-
起来没啥特色 |
|
n****o
发帖数: 41 | 2 admire .....
Is TS9 a good replacement for TS808? Sounds good? It is much cheaper ~~~~
自己的setup啊，用过的effect pedal 也拿出来晒晒吧！！期待xchain奔他的器材！
就买了这个，比较便宜不过感觉好像没太大分别，而且这个
用的空间比较小，所以就用了
的effect都很好,特别是Undulator。本来想买Electro-
起来没啥特色 |
|
l*******g
发帖数: 4894 | 3 看了这个我发现我都不是器材组的。
自己的setup啊，用过的effect pedal 也拿出来晒晒吧！！期待xchain奔他的器材！
就买了这个，比较便宜不过感觉好像没太大分别，而且这个
用的空间比较小，所以就用了
的effect都很好,特别是Undulator。本来想买Electro-
起来没啥特色 |
|
x****n
发帖数: 2297 | 4 根据我的记忆，TS9DX 声音较为硬朗。
我也非常喜欢 Eventide 的 TimeFactor，没用过 ModFactor, 不过这款好评如潮啊。
MT-2 是一个很 tricky 的 pedal.
我上个星期还和路易讲，不用买 pedalboard 的。 到Home Depot 割块木板，再贴上
velcro 就好了， 你看人家Zakk Wylde ..
自己的setup啊，用过的effect pedal 也拿出来晒晒吧！！期待xchain奔他的器材！
就买了这个，比较便宜不过感觉好像没太大分别，而且这个
用的空间比较小，所以就用了
的effect都很好,特别是Undulator。本来想买Electro-
起来没啥特色 |
|
t********t
发帖数: 5415 | 5 自用，琴是fender american std strat（用到年底）和ibz js1000.
amp不想（也不能）买太大，住个小studio...估计marshall mg30fx到头了，但是那上
面的effect我也不用，有点浪费...
effect要有USB，要不然还得另搞interface去。目前看上的是pod hd500，曾经对gt10
很有感但是后来不这么想了...
高人们有什么好建议没？ |
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p**k
发帖数: 120 | 6 For Multi-effect:
You will always need a multi effect if you play electric(in
my opinion, that is). For limited budget, you can get an
original Zoom 505 for less than 70$ everywhere( I saw
sam-ash brick and mortar store was selling it for 60$ a
while ago). For a little bit more ($100 or so) you can get a
new version Zoom 505 or Digitech rp-100. Both these models
were just released and I do suspect that they are way better
than original 505 (based on the reputations of the
manufacturer).
|
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c**********a
发帖数: 6 | 7 Effective application of dendrimers in the field of ultra-low pressure
reverse osmosis membrane.
Dendrimer-based ultra-low pressure reverse osmosis membrane can effectively
retain a variety of salts, such as sodium sulfate, sodium chloride,
magnesium sulfate, retention rate reaches 92%, in particular sodium sulphate
, up to 98%. The membrane has high flux, and low operating pressure. Water
flux can reach 30-40 L • M-2 • h - 1, operating pressure was 0.
6MPa. The film has good resista... 阅读全帖 |
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s*****7
发帖数: 433 | 8 severe asthma 症状和COPD很像的，所以不要瞎猜。一般COPD是老年病，也不像Asthma
那样时好时坏，好的时候和正常人/毛一样。临床诊断是用了支气管扩张药后FEV1/FVC
仍旧小于0.7 (不知道是否适用于咪)，当然还有其它辅助诊断的标准。不过治疗用药两
种病都差不多。
我也不知道为啥流口水，不过Albuterol(beta2-agonist)一般还是挺安全的药。要不和
你的Vet讨论下能不能用另外一个药Ipratropium,这也是个支气管扩张药，而且针对COPD兼治
asthma,但是药理上
不同(anticholinergics),这药的side effect有一条就是口水少。Boehringer
Ingelheim出的Combivent就是Albuterol和Ipratropium的合剂。
Therapeutic window就是有效用药的区间，用少了没疗效，用多就overdose。大多数
corticosteroid的肺部给药都suffer这个窄区间。
给药方式应该行的，一般喷完Fluticasone要漱漱口，或许咪不会漱口，就只好流哈喇子解决
了。
Bl... 阅读全帖 |
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wh
发帖数: 141625 | 9 还是关于牡丹亭的翻译，原文是：
In dream，each knows the other's name. Liu Mengmei's dream girl calls to him
young man to approach her partly because he knows who she is: "I was on my
way to follow Miss Du home." Inexplicably, they sing to each other: "Where
have we seen each other before? Now we gaze at each other silently."
看我傻乎乎的翻译：
在梦里，两人都知道对方的姓名。柳梦梅的梦中女郎叫他“柳郎，柳郎！”；而杜丽娘
在梦中接受年轻男子的亲近，部分原因正是他知道她是谁：“小生顺路儿跟着杜小姐回
来。” 他们莫名其妙地对唱：“是那处曾相见，相看俨然，早难道这好处相逢无一言
？”
“部分原因”翻得不大顺是不是？“莫名其妙”是不是也很怪？文章是想说他们明明不
认识，在梦里却莫名其妙地认识。有更合适的... 阅读全帖 |
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w********1
发帖数: 3492 | 10 Thu, 28 Jun 2012 06:54:23 PDT
Earlier this week, U.S. District Judge Lucy Koh granted a preliminary
injunction that would allow Apple to bar Samsung from selling its Galaxy Tab
10.1 in the United States while a full trial on Samsung's alleged design
infringement is conducted.
Enforcement of the sales ban required that Apple post a $2.6 million
bond from which damages to Samsung would be paid if Apple ultimately lost
its infringement case, and FOSS Patents reports that Apple has indeed moved
... 阅读全帖 |
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e******r
发帖数: 76 | 11 Effective C Sharp 50 Specific Ways to Improve Your C Sharp
这本书像 Effective C++ 55 Specific Ways to Improve 那样经典吗？
有没有其他 C Sharp 的经典书籍？
谢谢 |
|
h**2
发帖数: 2841 | 12 Battlefield 3游戏的deal是一个接一个，其实tmd不就是5块5块的降吗！
不过是个40多块的游戏，得配$200块的显卡才能勉强玩得爽，为了最爱的jets还得买新
摇杆，又是$50……(定义：爽=1920x1080, 特效全开 ，min.FPS>35)
发行好几个月了，看看这个显卡要求，还是心凉！
http://www.pcgameshardware.com/aid,851282/Battlefield-3-11-Rade
EA总是一个接一个的树立标杆，上次Crysis Effect才过去多久，这BF3又逼着来个大跃进
过几个月吧，等买得起这样的硬件，再买了BF3的游戏，登到服务器上一露头，又见老
鸟成群组队虐菜鸟，又要做noob给人humiliate……
算了，继续在BF2里虐noob自慰吧 |
|
S****z
发帖数: 666 | 13 原来这书作者是在BSO它自己的safe而其他书的不safe是吧
好吧，这次忍了，再往下读读看
BTW：貌似还有本叫More Effective C++？既然它叫More Effective
那More的作者应该比这个没有More的更牛叉吧，我是不是直接读那本就行了
没必要在这本没有More的上浪费时间？ |
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s*****t
发帖数: 1994 | 14 A Force from Empty Space: The Casimir Effect
Credit & Copyright: Umar Mohideen (U. California at Riverside)
Explanation: This tiny ball provides evidence that the universe will expand forever.
Measuring slightly over one tenth of a millimeter, the ball moves toward a smooth plate in
response to energy fluctuations in the vacuum of empty space. The attraction is known as the
Casimir Effect, named for its discoverer, who, 50 years ago, was trying to understand why
fluids like mayonnaise m |
|
h*******e
发帖数: 205 | 15 Genetically modified organisms (GMO’s) are a broad group of plants, animals
, and bacteria that are engineered for a wide variety of applications
ranging from agricultural production to scientific research. The types of
potential hazards posed by GMO’s vary according to the type of organism
being modified and its intended application. Most of the concern surrounding
GMO’s relates to their potential for negative effects on the environment
and human health. Because GMO’s that could directly effect |
|
G*****h
发帖数: 320 | 16 个人理解，不一定完整：
【背景】：
如果 2 药物（A、B）纯粹作用同一个药靶或者途径（not independent），那么“最大
”效果一致（maximum responses/effects）。这时候出现的是 additive effect。或
者说，在 A 里面加些 B 时候，也就是等于在 A 里面多加了些 A）。
另外情况是 A、B 作用为 independent to each other，或者 partially dependent（
这时应该不止一个药靶，但其中一个是吻合的）。
【如何检测】：
最简单合适的方法应该做 3 个 dose response 曲线（浓度从 0 到 最高）：A、B、和
A+B combined。
然后看 A+B 的曲线，是否吻合 A 和 B 两个曲线的简单叠加，同时做个 significance
test。
1）等于叠加、或者几乎是叠加 = additive
2）显著地低于叠加 = negative synergy
3）显著地高于叠加 = positive synergy
也要考虑这3种情况的程度之分（效果好坏的程度）。
欢迎讨论和补充！ |
|
发帖数: 1 | 17 比如一个384孔板，一个sample至少要6个孔（3 replicates for target gene and 3
for gapdh control）
这样最多能同时做64个样本
但如果超过64个样本怎么办呢？那就只能分两批做，可是这样会有batch effect，就是
每一“锅”的qpcr都是不太一样的，两“锅”data直接拼到一起比较，是不是有问题？
有没有啥好办法remove batch effect呢 |
|
x*****e
发帖数: 309 | 18 batch effect没想象的那么大吧？如果真的和hcy的batch effect那么大，这实验没法
做或者多优化多练习吧。 |
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h**********a
发帖数: 298 | 19 need more details about your data and model.
But upon the information you provide, country fixed effect can be removed by
the mean differencing since a country could export several products.
Product specific fixed effect probably can't be removed if you only have one
year data. |
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s*****w
发帖数: 2065 | 20 fixed effect可以用dummy variable建模。
但是如果两个fixed effect在一个model里，会出现问题。
具体怎么回事去找本wooldrige的书看看吧 |
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s*******d
发帖数: 126 | 21 I have heard people talking on radio about consumer spending has this
multiplicative effect and that if more and more people start to spend,
economy will turn around faster. But since people are not spending, someone
has, and this someone turns out to be the government who is borrowing
heavily and spending like crazy. It makes sense to me that if the government
has spent in one shot but failed to get you and I to spend, the economy
does not get this multiplicative effect/boost and it is less lik |
|
w****r
发帖数: 748 | 22 Fixed Effect跟Random Effect的本质区别是v_i项是不是跟independent variables 相
关。当然，这是个不严谨的说法，严谨的说法参看wooldridge的讨论，我比较喜欢他的
argument。 |
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s********k
发帖数: 6180 | 23 right，所以capture effect能够提高throughput，不过也有人质疑其能量消耗以及
near far的问题。就能量问题，从电路角度肯定比不开capture effect消耗大，不过从
系统角度未必。因为省掉了很多不必要的重传。第二个问题我觉得CCA的存在也会解决
绝大部分near far的问题 |
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w*******n
发帖数: 1 | 24 达人们，一辆车穿过双黄线，撞了我左边道的摩托车，然后摩托车被撞飞后又撞在我车
上，车左边全部烂掉。。。警察认定是那个人的责任，我也拿到了事故报告，但是给对
方保险公司打电话，被告知对方的保险not in effect。什么是not in effect？像这种
情况，我怎么索赔呢？另外，是摩托车撞的我，虽然摩托车并不是肇事车，那我可不可
以联系摩托车的保险公司，让他们给赔付，然后摩托车保险公司再去找肇事车主或者他
的保险公司呢？谢谢达人！ |
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l***d
发帖数: 1828 | 25 Enhanced Permeability and Retention (EPR) effect,大概多大的macromolecule
可以引发VEGF 的EPR effect。我听一个报告说polymer大概要40K,但多糖的话10K左右
就可以，这个好像在drug delivery 里面应用很多。为什么会这样？有没有了解的人谈
一谈,先谢谢了。 |
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h*********g
发帖数: 78 | 26 Enhanced Permeability and Retention 主要指的尺寸吧，比如，frechet 做树状分子
时，都说的EPR和尺寸的关系。尺寸大到一定的尺度（50nm ？），被身体排出的half
life就增长了，一半小分子大改是小于30 分中什么的.
VEGF 和EPR effect我就有点不理解了，我做过VEGF控释，可我从来没有考虑过它的EPR
effect，它不是很容宜被分解什么的么。 |
|
t***u
发帖数: 20182 | 27 Weissenberg effect
什么是non-zero first normal stree difference?我的想法是不是就象飞天转轮一下
给甩起来了？
From wiki：
The Weissenberg effect is a common phenomenon that occurs when a spinning
rod is placed into a solution of liquid polymer. Instead of being thrown
outward, entanglements cause the polymer chains to be drawn towards the rod.
It is named after Karl Weissenberg.
Technically, it is due to a non-zero first normal stress difference. The
strain tensor of the motion of turning the rod produces a non-zero
diffe |
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w***e
发帖数: 269 | 28 confounding是指一个因素如果和 factor of interest以及effect都有关系，但是又不
是在factor of interest 和 effect 的因果关系上，那么就是confounding factor.
比如说男性肺癌比例高，吸烟可以算作一个confounding factor.因为并不是男性和吸
烟有因果关系，但是两个有关。反而看你的这个问题，OCP和家族病史没有关系，所以
家族病史不是OCP causing breast cancer的confounding factor. |
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m******i
发帖数: 834 | 29 Quantum Size Effects in Metallic Nanostructures
Michael C. Tringides
Iowa State University, Ames
Mieczyslaw Jalochowski
Maria Curie-Sklodowska University, Lublin, Poland
Ernst Bauer
Arizona State University, Tempe
In solid-state physics, crystals are usually assumed to be large enough that
the influence of finite dimensions on their electronic structure is
negligible compared to the effects of the periodic potential produced by the
regular arrangement of the ion cores. Th |
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h********g
发帖数: 5 | 30 Ming Liu and Fuqian Yang, Finite element simulation of the effect of
electric boundary conditions on the spherical indentation of transversely
isotropic piezoelectric films, Smart Materials and Structures 21 (2012)
105020 (10pp)
Finite element simulation was used to analyze the effect of electric
boundary conditions on the
indentation deformation of a transversely isotropic piezoelectric film
with the contact radius
much larger than the film thickness. Six different combinations of... 阅读全帖 |
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s********r
发帖数: 295 | 31 E-Verify Federal Contractor Rule Effective 9/8/09!
The USCIS issued a press release reminding federal contractors and
subcontractors that effective yesterday (9/8/09) they may be required to use
the E-Verify system to verify their employees' work authorization if their
contract includes the Federal Acquisition Regulation (FAR) E-Verify clause.
The E-Verify federal contractor rule extends the E-Verify system to federal
contractors and subcontractors, including those who have received TARP funds
. |
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s*********s
发帖数: 18 | 32 小弟正在做spin hall effect in graphene.
敬请前辈给点指教！
i.e
1.如何控制graphene边缘态edgy state(zigzag、 armchair )
2.结构如何设计spin hall effect configuration（big spin diffusion length)
3.如何提高graphene spin-orbit interaction(graphene weak SOL) |
|
m********t
发帖数: 121 | 33 几年前我是一个笃信星座的人，跟陌生人见面，头两句话里就会问：你是什么星座的？
找男朋友也是非水相星座的不考虑。直到有一天接触Forer Effect (Barnum Effect)，
才重新审视我信奉了颇久的星相。以下是转自wiki的内容：
Forer's demonstration
In 1948, psychologist Bertram R. Forer gave a personality test to his
students, and then gave them a personality analysis supposedly based on the
test's results. He invited each of them to rate the analysis on a scale of 0
(very poor) to 5 (excellent) as it applied to themselves: the average was 4
.26. He then revealed that each student had been given the |
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y******g
发帖数: 317 | 34 ☆─────────────────────────────────────☆
mochascent (Life Is Beautiful) 于 (Tue Dec 5 23:31:49 2006) 提到:
几年前我是一个笃信星座的人，跟陌生人见面，头两句话里就会问：你是什么星座的？
找男朋友也是非水相星座的不考虑。直到有一天接触Forer Effect (Barnum Effect)，
才重新审视我信奉了颇久的星相。以下是转自wiki的内容：
Forer's demonstration
In 1948, psychologist Bertram R. Forer gave a personality test to his
students, and then gave them a personality analysis supposedly based on the
test's results. He invited each of them to rate the analysis on a scale of 0
(very poor) to 5 (excelle |
|
d********e
发帖数: 5 | 35 看了两遍effective C++,想继续提高一下,但是时间比较紧,不太可能全读完,请面过
quant analyst或quant developer的人给提提意见. |
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b***k
发帖数: 2673 | 36 effective give you 50 tips,
and more effective give 35 more tips.
其实这两本书都是在对C++基本概念熟悉并且有了一定工程实践之后
才应该阅读的，是前人（牛人）的经验和教训的总结。
我不觉得C++ entry level的人应该读这个，虽然可能读起来显的很
轻松，可是深入理解是不可能的。倒是那些设计工程的人需要备一份，
开工前多看看，可以避免以后少走很多歪路。
但有人说读了这些书对应付面试有好处，我想也许唯一的办法就是
死记硬背那些tip了，不多，两本书总共才85个。呵呵。
Efficient |
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y*w
发帖数: 238 | 37 effective可能新手可以看看
more effective后面半本新手几乎不可能读懂 |
|
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m*******7
发帖数: 244 | 39 Does any one have an electronic version of Mixed Effect Model, GEE class
notes ?
How is GEE related to Mixed Effect Model? Could anyone please explain to me?
Thanks. |
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h****s
发帖数: 16779 | 40 Both GEE and Linear Mixed Effects Model (LMM) can be viewed as special cases
of the Generalized Linear Mixed Effects Model (GLMM):
GEE is the population averaged (PA) marginal model of GLMM, see Zeger, Liang
, Albert, 1988, Biometrics, 1049-1060.
LMM is the GLMM with normal distribution and identity link function, see SAS
help. |
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C******n
发帖数: 284 | 41 貌似版上用Stata的不多，但愿熟悉random effects model的大牛们能提供些指导
我在Stata中用某些procedure，比如xtmelogit来做一个简单的two-level random
intercept logit model
在output中，by default，显示的是standard deviation of the random intercept，
如下表：
Random-effects Parameters | Estimate Std. Err. |
|
d**********r
发帖数: 24123 | 42 同赞。个人的理解是 Fixed Effects 是俺选取的，而Rabdom 不是自己控制的。
比如天气。
如果你专门选择晴天和雨天来做，那么这个天气就是Fixed。
如果你不专门挑选晴雨，碰到什么就是什么，那么这个天气就是Random |
|
F****n
发帖数: 3271 | 43 I don't think what you say has anything to do with fixed / random effects.
1. 如果你专门选择晴天和雨天来做，-- That only means your population is only
晴天 + 雨天 because you are particularly interested in contrasting these two
groups. Your results will only reflect the variation between these two.
2. 如果你不专门挑选晴雨，碰到什么就是什么 -- That means you are modeling the
entire population. |
|
p******r
发帖数: 1279 | 44 请问continous的indep variables会有interaction effect吗？
我知道categorical的indep variables要去看下interaction effect是否significant
，但如果indep variable是continous的呢？ 有必要或者说理论上允许不允许去看他们
的interaction term啊？
谢谢！！ |
|
s*******e
发帖数: 226 | 45 The model is
Y_it=aX_t-1+bX_t-2 + control variables_it
a and b are both significant, how to effectively explain the effect of X_t-1
and X_t-2 ( the same variable with different lags)together?
Thank you very much in advance. |
|
e****t
发帖数: 766 | 46 suppose, each patient will be measured at 1,2,3,4 time, but there is missing
value at different timepoint.
we fit model as
proc mixed ;
class sub time trt ;
model sub = time trt time * trt;
repeated time / sub = sub type = un ;
lsmeans trt * time / pdiff ;
run;
when calculating effect size,
we use ls Means diff / (SE / sqrt (1/n1 + 1/n2))
here n1 and n2 should be patient number in different group.
or should be patient number in different group by visit (due to missing,
observations at each visit... 阅读全帖 |
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k****e
发帖数: 23 | 47 今天电话面试, 结果被问到这个问题, 我就按照当时课上面学的, 说random effects
是因为sampled from a distribution (其实当时学的就很糊涂); 结果对方不是太满意
,让我举例说明, 我就不知道该咋说了.
面试肯定黄了; 大家教教我吧, 这两者究竟怎么去区分? |
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n**m
发帖数: 156 | 48 我是这么理解的，
一般fixed factor是我们对这几个factor的effect感兴趣，比如你想知道某种药的效果
，某种教学方法对学生的成绩有没有提高。
random factor我们对factor中某个个体不感兴趣，但是random factor解释variation
，帮助设计正确的model。
另外，有一些条件限制，比如factor只有几个个体，比如3个，用random factor就不太
合适。有时候个体太多了，比如20多个，就会比较倾向于设计成random factor。 |
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s*********e
发帖数: 1051 | 49 it is very interesting http://statcompute.wordpress.com/2012/09/30/marginal-effects-on-binary-outcome/.
you might test it yourself. as shown in many research literature, marginal
effects across different classes of models can be very much similar even
with substantial differences in model specification and assumptions. this is
very useful information in the content of model comparison. |
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A*******s
发帖数: 3942 | 50 非常有趣，读lz的blog受益良多。
logit和probit实质上没有什么差别，因为standard normal distribution和scaled
logistic distribution with unit variance的形状是很相近的。logit和probit的系
数的关系大概是1.6至1.8的关系，但是对应的std dev也是同样的倍数关系（因为
standard normal和standard logit的square root of variance也是同样的倍数关系）
，所以两者的t statistics和p-value非常接近。marginal effect是相同应该也是同样
道理吧。
其他model为啥marginal effect相同我就不清楚原因了。
is |
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