l**********1
发帖数: 5204 | 1 庄只是徐福炼丹 给秦始皇炼那个长生不老丹吧?
Xiaoliang Sunney Xie
Raman Scattering is King Route to 单分子Raman scattering 光 (possible)
1)
Single DNA molecule detection in an optical trap using surface-enhanced Raman scattering
//apl.aip.org/resource/1/applab/v96/i21/p213701_s1
Abstract:
Raman spectra from single DNA molecules in their natural aqueous environment are presented. A DNA molecule that is anchored between two optically trapped dielectric beads is suspended in a solution with nanosized silver colloid particl... 阅读全帖 |
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l**********1
发帖数: 5204 | 2 单分子RNA-seq 测序仪器的错误率从15%减少到了不到0.1%。
pls refer :
美研究人员成功解码“学习能力”相关基因
translation from article:
Hybrid error correction and de novo assembly of single-molecule sequencing
reads
by
Koren S. et al. Nat Biotech (2012)
2012-07-18
据外媒报道，有US科学家称，他们组合了一条更完整的基因链条，这个基因链条可
以控制鹦鹉模仿主人和其他声音的能力。
研究者用一种新技术分解了鹦鹉的基因组中的某个区域，进行了单分子测序，并用
来自较早的DNA解码设备的数据对其进行了纠错。研究者还解码了来自玉米和细菌的难
以测序的基因物质，以此来证明他们新的排序方法。
单分子测序“在去年获得了大量宣传”，因为它产生了测序长读取，“使组装基因
组中的复杂部分变得更容易，”研究参与者之一，Duke大学的神经生物学家Erich
Jarvis说。
Jarvis对那些控制鹦鹉模仿能力的序列很感兴趣，因为它们能... 阅读全帖 |
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k*****1
发帖数: 454 | 3 你对Boltzman's principle的理解完全错误的。Boltzman's principle 只能用来描述
类似于 气体分子/离子 这样的微观分子，而voltage sensor简直是不知所云。
（1）在原文当中，已经很明确的写了，“From Boltzmann's principle the
proportion Pi of the molecules on the inside of the membrane is related to
the proportion on the outside, PO, by Pi/PO==exp[(w + zeE)/kT]," 这是非常经
典的热力学上描述分子在某个能量状态下的概率。比如说 “Pi” 就是 某（带电）分
子位于细胞膜内部的概率（看原文！！） 对了，很好奇的问一下你的本科背景是什么
？你学过统计物理或是热力学吗？
(2)你一直强调的那个voltage sensor 和 6个电荷是怎么来的呢？ 原文当中也解释的
很清楚：
由上面的方程组可以得出： Pi =constant x exp[zeE/kT]. 记住，在这里 Pi是... 阅读全帖 |
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w***x
发帖数: 265 | 4 “所以从统计物理的角度上，同时又最贴近实际情况来理解 H-H 模型，就是 首先确定了
钠离子在细胞内部的概率为P1，细胞外的概率为P0，其中P1+P0=1 并且 P1/P0=exp（函
数）”
真心不是Na离子，我粘贴原文：
In order to illustrate the possible meaning of this result we shall suppose
that a charged molecule which has some special affinity for sodium may rest
either on the inside or the outside of the membrane but is present in
negligible concentrations elsewhere. We shall also suppose that the sodium
conductance is proportional to the number of such molecules on the inside of
the membrane ... 阅读全帖 |
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s****l
发帖数: 10462 | 5 NIH最近又房顶了八个小组，大家看看哪一个最有可能成功？
The new grants are awarded (pending available funds) to:
University of California Santa Cruz, $2.29 million over three years
Principal Investigator: Mark Akeson, Ph.D.
Investigators plan to sequence single DNA molecules by using a nanopore
device comprised of a sensor that touches, examines and identifies each
nucleotide, or DNA building block, in a DNA strand as an enzyme motor moves
it through the pore. The scientists will focus on DNA “resequencing” —
examining th... 阅读全帖 |
|
s****l
发帖数: 10462 | 6 NIH最近又房顶了八个小组，大家看看哪一个最有可能成功？
The new grants are awarded (pending available funds) to:
University of California Santa Cruz, $2.29 million over three years
Principal Investigator: Mark Akeson, Ph.D.
Investigators plan to sequence single DNA molecules by using a nanopore
device comprised of a sensor that touches, examines and identifies each
nucleotide, or DNA building block, in a DNA strand as an enzyme motor moves
it through the pore. The scientists will focus on DNA “resequencing” —
examining th... 阅读全帖 |
|
l********k
发帖数: 14844 | 7 【 以下文字转载自 Military 讨论区 】
发信人: lunchbreak (考不上印度理工，才到麻省理工来), 信区: Military
标 题: 也谈偷idea：庄小威STORM之前，很多工作已经铺好路了
发信站: BBS 未名空间站 (Thu Oct 9 12:49:44 2014, 美东)
STORM的关键，除了这个荧光分子轮着闪、单个定位这个方法上的技巧之外，最最最关
键的是switchable dye. 只要掌握了这个东西，STORM也好，PALM也好，高中生、甚至
初中生都可以理解原理，甚至原创出来。庄小威是化学出身，之前研究的一个方向也正
是这个switchable dye, 比如她在2005年的这篇论文（STORM, PALM都是06年的工作）：
Short-Range Spectroscopic Ruler Based on a Single-Molecule Optical Switch，
Phys. Rev. Lett. 94, 108101 – Published 15 March 2005
有了这个东西，基本上距离STORM只有一步之遥了。
但是很... 阅读全帖 |
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s********6
发帖数: 89 | 8 http://www.amc.edu/PR/PressRelease/04_20_15_drs.html
http://www
Albany Med Announces 2015 Recipients of Albany Prize in Medicine
Albany, N.Y., April 20, 2015—A pair of scientist/inventors who developed
widely used modern research technologies that promise to accelerate medical
discoveries have been announced as the recipients of the Albany Medical
Center Prize in Biomedicine and Biomedical Research for 2015. They are:
Karl Deisseroth, M.D., Ph.D., D.H. Chen Professor, Professor of
Bioengineering... 阅读全帖 |
|
S******G
发帖数: 965 | 9 quote
" In that situation the molecules are barely mobile and won’t react because
the Pauli principle forbids them from interacting. When the researchers
flipped the orientation of the nuclear spins of some molecules so the waves
of the molecules could overlap, however, pairs of KRb molecules
with different nuclear spins reacted to produce K2 and Rb2, even when the
original molecules were as far as 1 μm apart."
介个是成功率是１００％的有效碰撞。
打个比方，没有互联网之前两地没法谈恋爱，因为彼此的信息接受不到，你也不知道对
方是不是异性呢。所以只有自己找老妈寻同事介绍。现在通过网 |
|
g******h
发帖数: 101 | 10 http://chemistryjobs.acs.org/jobs#/detail/5305585/1,false
esearch Associate / Assay Development POSTED: Apr 04
Salary: $ 35,000.00 - 45,000.00 Location: East Lansing , Michigan
Employer: Michigan State University Type: Full Time - Experienced
Field of Specialization: Analytical Work Function: Quality Control/
Analysis, Research-Applied
Required Education: Doctorate
We seek an analytical/organic/medicinal chemist to develop assays to measure
pheromones and o... 阅读全帖 |
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s****n
发帖数: 212 | 11 1, what effect will using an 900MHz NMR rather than a 300MHz NMR spectrometer
have on the linewidths of a molecule with a molecular weightof (1)1000;
(2)10,000;
Why?
2,Explain why small molecules(MW<500 Da)GENERALLY HAVE more narrow resonances
than large molecules(MW>3000 Da)?
3,Explain why moderately large molecules(MW in a range of
1000-10,000)GENERALLY HAVE more narrow resonances than very large
molecules(MW>100,000 Da)
非常谢谢！ |
|
E***n
发帖数: 308 | 12 classic vaccine/bio pharmceutical companies don't require organic chemists.
Nowadays, it is a fashion for large molecules companies to do some small
molecule, small molecule pharms buy some large molecule companies.
some are successful such as millennium. They got a small molecule drug with
mw ~350. |
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m**********7
发帖数: 13 | 13 Recruiter给我推了一个位置，需要至少Analytical Chemistry的Master或PhD，strong
experience in LC-MS small molecule analysis，Salary is $65-85K. No sponsor.
如果谁感兴趣的话可以发简历给我 [email protected]/* */，我转给Recruiter. 位置在WI.
Please send your resume asap if you are interested since I am not sure how
long this opening could be available.
Description：
Senior Analytical Chemist position
Job Description:
· Perform quantitative method development, validation, and analyses to
support a chemical manufacturing facility
· ... 阅读全帖 |
|
p*******g
发帖数: 2976 | 14 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时，深深的鄙视一下自己的无聊行径！！
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
|
发帖数: 1 | 15 名字叫舍恩。
德国科学家。不少Nature，Science。后来均被撤稿。
以下摘自维基百科。将军们怎么看这位白人科学家？据一位王姓的华人知名professor
透露，他去演讲，有个欧洲白人老头老是说华人professor的文章是造假造出来的数据
，华人教授气都气死了。
【舍恩事件】
舍恩事件是一起于2002年揭发的大规模学术论文造假丑闻。事件主角扬·舍恩 (Jan
Hendrik Schön) 1970年生于德国费尔登，1997年获康斯坦茨大学物理学博士学位
并留校任教，1998年加入贝尔实验室，于贝尔特拉姆·巴特洛格教授指导下做材料学研
究，2001年成为正式员工。之后的4年里，他与20多人合作在许多大型国际期刊上发表
了超过80篇论文，在《自然》和《科学》上发表的第一作者署名的论文就有17篇。这些
论文在当时被认为于分子电路、分子半导体、有机激光、高温超导和纳米科技领域取得
突破进展，震动了整个科学界。2001年，他获得了德国最重要的科学奖项之一——奥托
·克隆-韦伯银行奖。
舍恩最出名的“成就”是于2001年11月发表的单分子场效应管。他称在两层金电极之间
用含硫的有... 阅读全帖 |
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x****6
发帖数: 4339 | 16
The occurrence of concentrated pneumonia cases in Wuhan city, Hubei province
of China was first reported on December 30, 2019 by the Wuhan Municipal
Health Commission (WHO, 2020). The pneumonia cases were found to be linked
to a large seafood and animal market in Wuhan, and measures for sanitation
and disinfection were taken swiftly by the local government agency. The
Centers for Disease Control and Prevention (CDC) and Chinese health
authorities later determined and announced that a novel coro... 阅读全帖 |
|
发帖数: 1 | 17
Download pdf published by SfN (Chapter from 'The History of Neuroscience in
Autobiography, Volume 8' edited by Larry R. Squire)
Yuh-Nung Jan's CV
Lily Jan's CV
Yuh-Nung Jan and Lily Jan
Birth
Family History and Growing Up
National Taiwan University
The Hiking Trip to Shitou in the Spring of 1967
Graduate School Application
Graduate Study at Caltech (1968锟974)
Seymour Benzer Lab (1974锟977)
Steve Kuffler锟絪 Lab at H... 阅读全帖 |
|
m****s
发帖数: 18160 | 18 【 以下文字转载自 Boston 讨论区 】
发信人: Sciex (LCMSMS), 信区: Boston
标 题: [供求][Job Opening]: Bioanalytical Scientist
发信站: BBS 未名空间站 (Wed Oct 31 11:18:01 2012, 美东)
My group will have an opening position for Bioanalytical Scientist soon.
This is a mid level position, so we don’t need PhD candidate. Meanwhile, we
only look for local candidate at Great Boston area. If you or someone has
interest, please drop me an email at p***[email protected].
Thanks,
Here is the job description:
Description of duties:
The successfu... 阅读全帖 |
|
c*****r
发帖数: 529 | 19 http://truthcdm.com/this-could-be-the-end-for-big-oil/
This Could be the End for Big Oil
stunning breakthrough in chemical engineering has unleashed a massive supply
of fuel…
Enough fuel, in fact, to power the entire globe for over 36,000 years.
It’s poised to decimate Big Oil’s obscene profits, make OPEC obsolete, and
hand the United States 100% energy independence.
In fact, the U.S. Department of Defense just invested $7 billion in a single
day…
Apple, Google, and Facebook are spending billion... 阅读全帖 |
|
f*******3
发帖数: 122 | 20 RE: Applicant’s Name
To Whom It May Concern:
This letter is written to recommend Dr. XXX as a scientist/researcher of
outstanding accomplishments and extraordinary ability in the field of
Chemistry, specifically, development of new reactions based upon Metal-
catalyzed C-H activation processes.
I am a Professor of Organic Chemistry at ___________________________. My
group is focused on development of catalytic reactions catalyzed by platinum
and gold catalyst. My group is also engaged in metal-c... 阅读全帖 |
|
s******l
发帖数: 192 | 21 工作地点在MIT.
简历请发送到[email protected]/* */
This technical assistant will help developing stem cell/small molecule based
therapeutic systems for mucosa-related diseases. The candidate for this
position will be responsible for stem cell culture, small molecule screening
, cell-based assays, animal studies and data analysis. The candidate will
have strong organizational and communication skills for assisting technology
innovators, engineers, biologists, and clinicians in a dynamic team
environmen... 阅读全帖 |
|
d**y
发帖数: 18174 | 22 他的衣服貌似不错，我还没这个牌子的湿衣。可惜太贵。不知道比xterra怎么样？
Gear Review: blueseventy Helix Wetsuit
Wetsuits are one of the larger gear investments a budding triathlete can
make; behind a bike and/or race wheels (if, of course, you fall into USAT's
median income range of approximately $108,000), it is likely a wetsuit will
be your most expensive piece of gear.
With that kind of money on the line, then, it stands to be prudent when it
comes to selection. Much like when it comes to proper triathlon bikes and
running s... 阅读全帖 |
|
h*d
发帖数: 19309 | 23 [PS3]开发秘辛1：《小小大星球》！
本文原载于游戏人，经过部分删改，未经许可，请不要转载，谢谢
《小小大星球》
制作公司：Media Molecule
游戏平台：PS3
发行日期：2008年10月28日
开发成员：31人
开发时间：2年
开发预算：未知
代码长度：未知
《小小大星球》的风行，即使对Media Molecule的员工来说都快的有些难以置信。接近
200万的活跃用户数量，数十万充满奇思妙想的玩家自制关卡，游戏3.0的时代似乎在顷
刻之间降临到游戏产业。从最初将自己的想法诉诸实现到成为游戏产业的一种热门趋势
，这中间确实存在一些可遇不可求的偶然因素，不过最重要的是，Media Molecule将纸
面上的好点子塑造成了一款极具魅力的游戏作品。面对如潮的赞誉和媒体的关注，他们
怎样保持冷静心态，并防止随着开发团队规模日益膨胀，所引发出的种种负面问题？当
公司创始人Alex Evans再次恼羞成怒的指责团队成员所犯的错误时，又该如何避免公司
的气氛因此变得糟糕？Media Molecule的另一位创始人Mark Healey给出了自己的答案
，“当我找到了一个比较满意的解决办 |
|
w******e
发帖数: 953 | 24 How safe does transgenic food need to be?
Laura DeFrancesco1
Journal name:
Nature Biotechnology
Volume:
31,
Pages:
794–802
Year published:
(2013)
DOI:
doi:10.1038/nbt.2686
Published online 10 September 2013 Corrected online 26 September 2013
Article tools
PDF
How safe does transgenic food need to be?
Download as PDF (812 KB) View interactive PDF in ReadCube
Citation
Reprints
Rights & permissions
Article metrics
Disputes over how to assess a foodstuff's safety continue to play into
public fears a... 阅读全帖 |
|
H********g
发帖数: 43926 | 25 【 以下文字转载自 Biology 讨论区 】
发信人: lyray (lyray), 信区: Biology
标 题: 人类灵魂就隐藏在DNA末端krypton原子
发信站: BBS 未名空间站 (Wed Aug 26 16:32:06 2015, 美东)
We owe the discovery of this mysterious biogenetic process to our scientist
AOYOO 221.
It had been discovered a long time before that in the human brain were
krypton atoms (a rare gas that you know), and this discovery was a
significant, transcendent one. It was quite simply the key to the OEMBUAW,
MAN'S THIRD FACTOR, which you do not know and which acts as a link be... 阅读全帖 |
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a**********e
发帖数: 418 | 26 Withdraw the first question. It's not valid.
Before making further discussion on how simple organic molecules formed in
the beginning, I would like to clarify the follow assumpion: My
understanding of nature or primitive stage of earth contained a bunch of
simple inorganic molecules, there should be no or very little organic
molecules that are key components of our body. And chemical reactions were
only able to occur to a certain degree. The primitive conditions could not
even get anywhere close... 阅读全帖 |
|
B******y
发帖数: 2255 | 27 回下这个。
Response:
1.The calculation of odds assumes that the protein molecule formed by chance
. However, biochemistry is not chance, making the calculated odds
meaningless. Biochemistry produces complex products, and the products
themselves interact in complex ways. For example, complex organic molecules
are observed to form in the conditions that exist in space, and it is
possible that they played a role in the formation of the first life (Spotts
2001).
是啊，任何一个100个氨基酸的长链都是极为复杂的complex product, ... 阅读全帖 |
|
d********r
发帖数: 3279 | 28 Arsenic-associated bacteria (NASA's claims)
ResearchBlogging.org
Wolfe-Simon F, Blum JS, Kulp TR, Gordon GW, Hoeft SE, Pett-Ridge J, Stolz JF
, Webb SM, Weber PK, Davies PC, Anbar AD, & Oremland RS (2010). A Bacterium
That Can Grow by Using Arsenic Instead of Phosphorus. Science (New York, N.Y
.) PMID: 21127214
Note to new readers: I wrote this post on Saturday Dec. 4, mainly to
clarify my own thinking. I didn't expect anyone other than a few
researchers to ever read it. Since then I've made ... 阅读全帖 |
|
f********n
发帖数: 6465 | 29 Aptamers are oligonucleic acid or peptide molecules that bind to a specific
target molecule. Aptamers are usually created by selecting them from a large
random sequence pool, but natural aptamers also exist in riboswitches.
Aptamers can be used for both basic research and clinical purposes as
macromolecular drugs. Aptamers can be combined with ribozymes to self-cleave
in the presence of their target molecule. These compound molecules have
additional research, industrial and clinical applications... 阅读全帖 |
|
h*******1
发帖数: 15 | 30 美国西北大学土木与环境工程系Prof. Yun Wang 招收联合培养博士生
Prof. Yun Wang from the Department of Civil and Environmental Engineering at
Northwestern University is seeking for Ph.D. candidates to conduct research
in her lab as exchange students under the joint-training programs sponsored
by China Scholarship Council (CSC). Students with educational background
in Environmental Chemistry, Microbiology, Molecular Biology, or related
majors are encouraged to apply. Successful candidates must have research
experience/i... 阅读全帖 |
|
h******y
发帖数: 1374 | 31 The Nobel Prize in Physiology or Medicine 2011
shall be divided, with one half jointly to
Bruce A. Beutler and Jules A. Hoffmann
for their discoveries concerning the activation of innate immunity
and the other half to
Ralph M. Steinman
for his discovery of the dendritic cell and its role in adaptive immunity
Summary
This year's Nobel Laureates have revolutionized our understanding of the
immune system by discovering key principles for its activation.
Scientists have long been searching for the g... 阅读全帖 |
|
c**c
发帖数: 11 | 32 我看他实验室网页的介绍，只剩下social behavior了。。
We are interested in the molecular and cellular mechanisms of social
behaviors.
Social behaviors are those initiated by one animal directed towards another
animal of the same species, ranging from social interactions in animals to
social relationships, politics and war in humans.
We use multidisciplinary approaches, integrating molecular biology, genetics
, neurobiology, chemistry, modern imaging and electrophysiology, to study
important and basic social behavio... 阅读全帖 |
|
s******y
发帖数: 28562 | 33 罗马的天主教大学研究人员发现，限制热量的饮食通过触发CREB1通路而激活
很多和长寿和脑健康有关的基因。
Eating Less Keeps the Brain Young
December 20, 2011
Overeating may cause brain aging while eating less turns on a molecule that
helps the brain stay young.
A team of Italian researchers at the Catholic Univ. of Sacred Heart in Rome
have discovered that this molecule, called CREB1, is triggered by "caloric
restriction" (low caloric diet) in the brain of mice. They found that CREB1
activates many genes linked to longevity and to the proper funct... 阅读全帖 |
|
s******9
发帖数: 283 | 34 其实楼主的问题我以前问过，当时没有什么讨论。再跟进一点想法：
高通量蛋白分析可以分in vivo（proteins in natural environment）和in vitro方法
。in vitro主要是protein array和Y2H，in vivo当然是MS。不用多说，各有明显优缺
点。
NGS的优点在于它是separation independent & single-molecule based。其他的
single-molecule技术都不能做high-throughput，原因是受限于limited fluorophores
。同理，蛋白分析能够也做到SM sensitivity和separation independent，将是true
breakthrough。
MS的优势很明显，但是sensitivity， throughput和cost-effectiveness都有瓶颈的。
所以in vivo基本无法做到single-molecule proteomics。但是对于in vitro，如果
protein被DNA barcoded（比如ribosome di... 阅读全帖 |
|
a**********2
发帖数: 3726 | 35 Thank you for your fair comment.
BRCA is not used for screening for breast cancer or ovarian cancer in
general population. For breast cancer screening, still mammography for older
than 50 yo. For ovarian cancer, no screening markers. BRCA test is only
used when there is strong family history of breast/ovanrian cancers.
As for treatment, Gleevec is one of the very few molecules that are targeted
for therapy. Compared with the numbers of known molecules in signal
transuction, the successful molec... 阅读全帖 |
|
p*****c
发帖数: 20445 | 36 Marc R. Freeman, Ph.D.
HHMI Early Career Scientist
University of Massachusetts Medical School
Neurons hog the attention, but our brains couldn’t operate without the
unassuming neural cells called glia. Marc Freeman is working to bring these
overlooked cells—which represent about 60 percent of brain cells—their
share of credit.
Freeman has been dissecting the role of glia in brain development, function,
and healing after injury, when glia hurry to the damaged area and devour
cellular debris to al... 阅读全帖 |
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l***y
发帖数: 1166 | 37 We owe the discovery of this mysterious biogenetic process to our scientist
AOYOO 221.
It had been discovered a long time before that in the human brain were
krypton atoms (a rare gas that you know), and this discovery was a
significant, transcendent one. It was quite simply the key to the OEMBUAW,
MAN'S THIRD FACTOR, which you do not know and which acts as a link between
the HEART and the BODY (BUAWAA and OEMII).
69 XEE before [approximately 18 months NdT ], in laboratory fertilization
experime... 阅读全帖 |
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a*****c
发帖数: 53 | 38 Rise to prominence[edit]
Schön's field of research was condensed matter physics and
nanotechnology.[3] He received his Ph.D. from the University of Konstanz in
1997. In late 1997 he was hired by Bell Labs, located in New Jersey, United
States. There, he worked on electronics in which conventional semiconducting
elements (such as silicon) were replaced by crystalline organic materials.
Specific organic materials can conduct electrical currents, and in a so-
called field-effect transistor (a ... 阅读全帖 |
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h*******1
发帖数: 15 | 39 美国西北大学土木与环境工程系Prof. Yun Wang 招收联合培养博士生
Prof. Yun Wang from the Department of Civil and Environmental Engineering at
Northwestern University is seeking for Ph.D. candidates to conduct research
in her lab as exchange students under the joint-training programs sponsored
by China Scholarship Council (CSC). Students with educational background
in Environmental Chemistry, Microbiology, Molecular Biology, or related
majors are encouraged to apply. Successful candidates must have research
experience/i... 阅读全帖 |
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h*******1
发帖数: 15 | 40 美国西北大学土木与环境工程系Prof. Yun Wang 招收联合培养博士生
Prof. Yun Wang from the Department of Civil and Environmental Engineering at
Northwestern University is seeking for Ph.D. candidates to conduct research
in her lab as exchange students under the joint-training programs sponsored
by China Scholarship Council (CSC). Students with educational background
in Environmental Chemistry, Microbiology, Molecular Biology, or related
majors are encouraged to apply. Successful candidates must have research
experience/i... 阅读全帖 |
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d*****s
发帖数: 313 | 41 I do not know.
What I am thinking now is, since in liquid, the distribution of molecules
is random, therefore, the "packing" of molecules should not be a factor.
Therefore, this leads to the assumption that the absorption wavelength of
liquids comes individual molecules.
However, what lets the individual molecule have color preference? Why
the absorption wavelength of metals is not governed by this molecular
absorption preference? |
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c**y
发帖数: 127 | 42 Single molecular biophysics这个领域不能算Steve Chu推动的吧，80年代到90年代中
期就有一些组用STM, AFM研究单个生物分子，Ronald Vale, Steve Block80年代末90年
代初就在玩 single molecule biophysics了，更不用说70年代就发明了patch clamp,
也算single molecule biophysics啊.我觉得Chu只是在适当的时候说了些话好像就把这
个single molecule biophysics变成显学了,其实已经有很多人在做了。
其实对于现在这么多人做single molecule,我倒是觉得不一定是什么好事，虽然这个蛋
糕很大。
饥渴的 |
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t*****e
发帖数: 133 | 43 各位大牛，请帮忙看看这个作业题，谢谢。
The following method is used to measure the molecular weight of very heavy
molecules. A liquid containing the molecules is spun rapidly in a centrifuge
, which establishes a variation in the density of the liquid. The density is
measured, such as by absorption of light, to determine the molecular weight
. Assign a fictitious "centrifugal" force to act on the molecules and show
that the density varies as
rho(molecule)=rho(liquid)exp(mw^2x^2/2kT), where w is the angular velocit |
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i*****e
发帖数: 1359 | 44 看看这个再说
http://www.grc.nasa.gov/WWW/K-12/airplane/wrong1.html
{Air molecules travel faster over the top to meet molecules moving
underneath at the trailing edge.} Experiment #1 shows us that the flow over
the top of a lifting airfoil does travel faster than the flow beneath the
airfoil. But the flow is much faster than the speed required to have the
molecules meet up at the trailing edge. Two molecules near each other at the
leading edge will not end up next to each other at the trailing edge as
... 阅读全帖 |
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k***a
发帖数: 92 | 45 Found a new paper on this subject: PRL 89, 093004
Here is the abstract:
A neutral polar molecule experiences a force in an inhomogeneous electric
field. This electric field can be designed such that a beam of polar molecules
is exposed to a harmonic potential in the forward direction. In this potential
the longitudinal phase-space distribution of the ensemble of molecules is
rotated uniformly. This property is used to longitudinally focus a pulsed
beam of ammonia molecules and to produce a beam |
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t*******n
发帖数: 4445 | 46 Man, it seems there are two issues here:
(1) Whether a molecule can absorb photon and have direct vibrational
transitions.
(2) If the above is true, whether the transition is in the IR spectral range
or not.
Your book answers the second one. On the first one, it depends on whether a
particular mode of vibration changes dipole moment or not. All polar
molecules are IR-active. But the reverse is not true since non-polar
molecules can have IR active modes, too.
In the NON-polar molecule CO2, th |
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a****y
发帖数: 1035 | 47 【 以下文字转载自 Biology 讨论区 】
发信人: hellowhy (夹死do it), 信区: Biology
标 题: 2011 Nobel Prize in Physiology or Medicine
发信站: BBS 未名空间站 (Mon Oct 3 08:44:48 2011, 美东)
The Nobel Prize in Physiology or Medicine 2011
shall be divided, with one half jointly to
Bruce A. Beutler and Jules A. Hoffmann
for their discoveries concerning the activation of innate immunity
and the other half to
Ralph M. Steinman
for his discovery of the dendritic cell and its role in adaptive immunity
Summary
This year's Nobel Laureate... 阅读全帖 |
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k**********e
发帖数: 643 | 48 黄从新语录
1.对下级：评选还没开始就知道结果
当2011年国家科技进步奖、973计划、国家十二五支撑计划还没有揭晓时黄从新在
全院大会上得意的说不出意外我今年就可以拿到国家科技进步奖二等奖一项、973计划
首席科学家一项、国家十二五支撑计划首席科学家一项。评选结果还没有公布，甚至评
选还没开始就宣布自己中了。
2.对无证行医的儿子：做手术死了人又不签你的名
黄鹤在2006年至2009年9月长达近4年的无证非法行医，并担任副主任医师期间，其
对临床是完全不懂的，其恐惧的问其父亲医死了人怎么办，黄从新指出做死了人又不签
你的名，你怕什么。结果每天的导管手术都安排没有经验的黄鹤上台期间医疗事故频发。
3.对媳妇：我是研究生院院长你怕什么
黄从新担任的另外一个职位是武汉大学研究生院院长，知情人士透露，其媳妇孙晶
认识黄鹤前只是一名企业普通员工，黄从新对她说我是研究生院院长你怕什么。安排其
媳妇在毫无英语和专业基础下神奇的考取武汉大学新闻学院单波的研究生，毕业后被黄
从新特招到武大研究生院担任学位管理的工作。
《新民周刊》在报道武大蛀虫陈昭方时指出“吴意梁还反映，“陈昭方从80年代中
期以来，... 阅读全帖 |
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w*********s
发帖数: 2136 | 49 Pictures Prove Mini Nukes Caused 9-11 Devastation
here are only two events known to cause ground-hugging pyroclastic flows (
pictured above).
1. A volcanic eruption
2. A thermo nuclear detonation
by “Dennis”
All research provided by:
www.drjudywood.com and http://911u.org/
On the morning of September 11th, 2001, we were told a fairy tale. That wide
body jets flew into the twin towers and completely destroyed them. Let me
repeat that: Passenger planes (large hollow aluminum tubes) flew into... 阅读全帖 |
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g***j
发帖数: 40861 | 50 【 以下文字转载自 Biology 讨论区 】
发信人: gshjj (各输己键), 信区: Biology
标 题: Tough Lessons From Golden Rice 不错的转基因故事
发信站: BBS 未名空间站 (Wed Mar 2 22:51:41 2011, 美东)
Tough Lessons From Golden Rice
Martin Enserink
It was supposed to prevent blindness and death from vitamin A deficiency
in millions of children. But almost a decade after its invention, golden
rice is still stuck in the lab
It's easy to recognize Ingo Potrykus at the train station in Basel,
Switzerland. Quietly waiting while hurried travelers zip ... 阅读全帖 |
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