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t***n
发帖数: 121 | 8 1. Curr Pharm Biotechnol. 2015;16(11):966-82.
Title : Process Development Strategies in Plant Molecular Farming.
http://www.ncbi.nlm.nih.gov/pubmed/26343135
3. Curr Protein Pept Sci. 2013 Nov;14(7):568-79.
Title : Heterologous production of peptides in plants: fusion proteins and
beyond.
http://www.ncbi.nlm.nih.gov/pubmed/23968345
4. Expert Opin Drug Deliv. 2015 Apr;12(4):653-67. doi: 10.1517/17425247.2015
.974546. Epub 2014 Oct 28.
Title: Elastin-like polypeptide for improved drug delivery for... 阅读全帖 |
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k****s
发帖数: 1209 | 11 原文在
http://www.skizit.biz/2013/07/21/ecdysone-insect-hormone-an-ind
Ecdysone Insect Hormone Switches on Disease
21 Jul 2013 | ECDYSONE
MORGELLONS:
INSECT HORMONE ECDYSONE TRIGGERS GENETIC CHANGES
TO BUILD NEW HAIR, SKIN, NAILS and CAUSE DISEASES
SkizitGesture-2013
Morgellons is a military grade entomological terror weapon being used to
torture and kill innocent civilians. The medical community has not been
informed about this disease and its complexity keeps it from being properly
identified, ... 阅读全帖 |
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J***n
发帖数: 210 | 17
Such studies are all over. Although there might be an acute increase of
testosterone level, endurance training generally reduces testosterone level.
You conclusion that "耐力运动员的testosterone绝对比举重的多" only shows you
ignorance on this topic.
Here are some "studies" from my causal search...
Reproducibility of low resting testosterone concentrations in endurance
trained men.
http://www.ncbi.nlm.nih.gov/pubmed/8817130
"Previous reports indicate endurance trained (ET) men have low resting
testosterone c... 阅读全帖 |
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l**********1
发帖数: 5204 | 19 大鼠/欧洲野兔/水䶄/鸡 的MHC 是越外(性)交: 路边的野花 不采白不采) 好似后代越advantageous哦
欧洲野兔 MHC paper:
Homozygosity at a class II MHC locus depresses female
reproductive ability in European brown hares
PubMed link:
//www.ncbi.nlm.nih.gov/pubmed/20731776
Wiki:
//en.wikipedia.org/wiki/European_Hare
水䶄MHC paper:
Selection Maintains MHC Diversity through a Natural Population Bottleneck
//www.ncbi.nlm.nih.gov/pubmed/22323362
Wiki:
//en.wikipedia.org/wiki/European_Water_Vole
据说恐龙演化过来的鸟类中的鸡 MHC paper
PNAS (2011)
Th... 阅读全帖 |
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l**********1
发帖数: 5204 | 20 Please refer below company CEO his resume:
//www.epitomics.com/about/about_management/
Epitomics dot Com CEO Guoliang Yu, Ph.D.
Dr. Guo-Liang is currently the Chairman and President of Epitomics, Inc. an
emerging biotech company dedicated to the development of innovative next-
generation monoclonal antibodies. Before starting Epitomics, he was the
Senior Vice-President of Research and Development in Mendel Biotechnology
Inc. Dr. Yu has broad technological and scientific experiences in many
aspec... 阅读全帖 |
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l**********1
发帖数: 5204 | 21 here you are:
A spatially distributed, signaling-transcription cascade robustly
discriminates between transient and sustained
ERK activities at the c-Fos system level:
//www.ncbi.nlm.nih.gov/pubmed/20493519
Stimulus-dependent MAPKs, ERK1/2 and ERK5, in DRG, motor neuron:
//www.ncbi.nlm.nih.gov/pubmed/21220101
Modeling review:
//www.ncbi.nlm.nih.gov/pubmed/16482094
Modeling cancer review:
//www.ncbi.nlm.nih.gov/pubmed/20836040
NGWet lab tools review:
//www.ncbi.nlm.nih.gov/pubmed/21999828
Conclus... 阅读全帖 |
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l**********1
发帖数: 5204 | 22 Please refer
Harmonics of Circadian Gene Transcription in Mammals
PLoS Genet. 2009 April; 5(4): e1000442.
Published online 2009 April 3
Validation experiments show that 12-hour oscillatory transcripts occur in several other peripheral tissues
as well including heart, kidney, and lungs. These harmonics are lost ex vivo, as well as under restricted
feeding conditions. Taken in sum, these studies illustrate the importance of time sampling with respect to
multiple testing, suggest caution in use of ... 阅读全帖 |
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l**********1
发帖数: 5204 | 23 Please keep in mind that original post
> 最初论文(publishe 50Y ago possible)
可能的时间跨度指1962-2011
any year is possible.
从最初投稿到accepted for publish
Cell 需时间 比N/S 长3～4倍
2006 Nobel winner
RNAi father: AZ Fire
//en.wikipedia.org/wiki/Andrew_Fire
RNAi within nematode
//www.ncbi.nlm.nih.gov/pubmed/10535731
over 13 month
N
//www.ncbi.nlm.nih.gov/pubmed/9486653
S
//www.ncbi.nlm.nih.gov/pubmed/1314423
both 4～5 month
不要说AZ Fire 以前没Cell 啊 至少有两篇
Cell. 1981 (3 Pt 2):555-61.
Inhibition of transcription factor ac... 阅读全帖 |
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l**********1
发帖数: 5204 | 25 Here you go, by bottom to up way: 以下括号内是按地区规模的比喻
Bibliography:
1, Deep Sequence Analysis of Non-Small Cell Lung Cancer: Integrated
Analysis of Gene Expression, Alternative Splicing, and Single Nucleotide
Variations in Lung Adenocarcinomas with and without Oncogenic KRAS Mutations
. (2012) (Newport beach, CA)
by
Kalari KR et al. and Thompson EA.
Front Oncol. 2:12. doi: 10.3389/fonc.2012.00012. Epub 2012 Feb 10.
Abstracts:
Our study is the first to integrate genomic features from RNA-S... 阅读全帖 |
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l**********1
发帖数: 5204 | 26 Pls check,
>This underlines the importance of identifying the presence and
understanding the function of these antisense non-coding RNAs. The
information concerning strand ori-gin is often lost during conventional RNA-
Seq; capturing this information would substantially increase the worth of
any RNA-Seq experiment. By manipulating the input cDNA during the template
preparation stage it is possible to retain this vital information. This
forms the basis of strand-specific RNA-Seq. With an ability ... 阅读全帖 |
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c**i
发帖数: 6973 | 29 (1) You say, "现在在国内."
Sorry, there is NOTHING anybody can do, now that the patient--er, the dog--
is in China. Say what you may, but China is no place to treat human or
animal patients.
(2) Jack Daniel Terrier
http://en.wikipedia.org/wiki/Jack_Russell_Terrier
(Originating in the early 19th century from dogs bred and used by Reverend
John Russell, it has similar origins to the modern Fox terrier)
(3) Google with the term (Jack Daniel Terrier spine)--not quotation marks--
and you will find many ow... 阅读全帖 |
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l**********1
发帖数: 5204 | 35 嗅觉的review:
//www.ncbi.nlm.nih.gov/pubmed/21297629
SOM pdf file link:
//www.nature.com/neuro/journal/v14/n3/extref/nn.2754-S1.pdf
-----
味觉的review:
//www.ncbi.nlm.nih.gov/pubmed/20696704
relative 2008 PNAS:
//www.ncbi.nlm.nih.gov/pubmed/18305172
more recently:
//www.ncbi.nlm.nih.gov/pubmed/21411651 |
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l**********1
发帖数: 5204 | 36 //www.ncbi.nlm.nih.gov/pubmed/21423173
//www.ncbi.nlm.nih.gov/pubmed/22308393
NB:
To
FAQ,
before you gave more details about the target you want to know i can not hit
above general cell membrane budding:
//www.ncbi.nlm.nih.gov/pubmed/21145455
and its paper:
//www.ncbi.nlm.nih.gov/pubmed/22067154
then Bottom to Top searching for getting above both papers.
Do you really think that all of them was not relative to your topic?
Conversion from Type B to Type A
It has been shown that lanthanides can ... 阅读全帖 |
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l**********1
发帖数: 5204 | 37 //www.ncbi.nlm.nih.gov/pubmed/15738949
//www.ncbi.nlm.nih.gov/pubmed/16980487
//www.ncbi.nlm.nih.gov/pubmed/18045498
//www.ncbi.nlm.nih.gov/pubmed/19959579
off
话说吧，哪个基因被敲除后bud就不长了，但细胞的其它进程不受影响。 |
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l**********1
发帖数: 5204 | 38 James Bailey's grandson within ME field.
//www.ncbi.nlm.nih.gov/pubmed/3277067
if Liu T. G. was similar to bleow guy whom some Bailey's grand grandson
noted last year paste.
only from PubMed,
Dr. Liu T. G. only one original paper during his PD training:
link:
//www.ncbi.nlm.nih.gov/pubmed/20184964
and two review articles:
0F Science review
plus
//www.ncbi.nlm.nih.gov/pubmed/20822440
all cited from
//www.ncbi.nlm.nih.gov/pubmed?term=%22Khosla%20C%22%5BAuthor%5D
so his PD 经历：
2008年--2010年
美国Chaita... 阅读全帖 |
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l**********1
发帖数: 5204 | 39 Exactly,
now is Prigogine Dissipative Structures Theory its turn within
Cancer Stem Cell Stochastic Systems Biology fields.
References:
1)
//www.ncbi.nlm.nih.gov/pubmed/21203505
2)
//www.ncbi.nlm.nih.gov/pubmed/21867509
3)
//www.ncbi.nlm.nih.gov/pmc/articles/PMC2754594/
4)
//www.ncbi.nlm.nih.gov/pubmed/21727130
5)
//www.bio.ucalgary.ca/contact/faculty/huang.html
About
Ilya Prigogine Dissipative Structures Theory/Non-Equilibrium Stastistical Mechanics
please refer:
http://www.mitbbs.com/article... 阅读全帖 |
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l**********1
发帖数: 5204 | 40 利用人工智能免疫系 likes CD44 plus Hyaluronan (hyaluronic acid, HA) is a
linear naturally occurring polysaccharide 钓3kDa左右的多肽的鱼
可以不通过分离而直接挑出peptide or protein来特异反应--just matrix two cents.
References:
1)
Erickson M, Stern R.
Chain gangs: new aspects of hyaluronan metabolism.
Biochem Res Int.2012:893947.
//www.ncbi.nlm.nih.gov/pubmed/22216413
and
2)
Chaim OM et al.(2011)
Brown Spider (Loxosceles genus) Venom Toxins: Tools for Biological Purposes.
Toxins (Basel). 3: 309-344
Abstract
Venomous animals use ... 阅读全帖 |
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b*********s
发帖数: 3863 | 46 受老同学所托,了解这方面的情况和治疗方案,自己收集了一点资料，希望能集思广益,
造福别人，高手见笑了。谢谢大家，能发到中文百科阿什么的也很感谢。
1.背景
2.varenicline 治疗
3. 辅酶 Q10的治疗
4.Sinemet (Carbidopa/levodopa)的治疗
1.背景
复原
康复专业人员（复健科医师，物理治疗师，职业治疗师，言语治疗师，和其他人）的管
理对步路/运动，日常任务，及言语障碍者的问题是必不可少的。
理疗可以帮助维持患者的运动性，将有助于防止挛缩。 [ 6 ]指导患者步态训练，将有
助于提高其流动性，减少跌倒的风险。 [25]物理治疗师也可以建议用行动辅助工具如
拐杖或助行器，以增加病人的安全。 [ 25]教他们从坐着到慢慢站立可以减少跌倒的风
险，并限制体位性低血压的影响 [ 25 ]在脚踝泵的指示（?）有助于腿的血液返回到全
身循环[25]为了进一步控制体位性低血压，可以在睡觉时提高床的头部（20.3公分），
以及利用弹性压缩服装。 [ 7 ]
言语及语言治疗师是评估，治疗和支持讲话（构音障碍）及吞咽困难（吞咽困难）的关
键 。吞咽困难的早期干预是... 阅读全帖 |
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e***n
发帖数: 138 | 48 多谢你详细的回复。我投的是一个很小的institute, National Library of Medicine.
以下是他们的官方解释。我真的属于比较倒霉的那种吧。
http://www.nlm.nih.gov/ep/Payplan.html
Fundable Range: NLM uses the overall Impact Score as the primary basis for
award decisions on all grant types, along with innovation and potential
impact. Generally, speaking, for experienced investigators, applications
with Impact scores 30 or better are the most likely to be funded. For Early
Stage Investigators and New Investigators seeking their first R01 research
grant... 阅读全帖 |
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c*******u
发帖数: 12899 | 49 ☆─────────────────────────────────────☆
littlehei (嘿嘿) 于 (Thu Mar 10 19:27:29 2011, 美东) 提到:
上大学新生入学体检的时候第一次检查出来，众目睽睽下几个肝感觉阳性的同学给点名
，被校医区别对待了，甚
至游泳卡也过了好久才拿到。。。当时只觉得无地自容，感觉被歧视了。
//幸好后来好像没有再这么被当众羞辱过。出国的体检，工作以后每年的体检都没有很
多废话。
后来我自己一直很注意这个方面的话题。得知我父亲年轻的时候得过乙肝，家里的孩子
成为乙肝病毒携带者也是
十有八九的事。虽然医学上说这个病毒携带是不可治愈也不可逆转的，还是相信民间偏
方吃了不少中药。小三阳
还是小三阳，姐姐是大三阳的，据说一度变成小三阳，现在不知道。因为美国好像没有
大小三阳的说法。
一直风平浪静的直到怀孕。第一trimester血结果出来以后，产科医生似乎有点紧张。
然后州政府的health
department给我打电话，说要把我登记在案。让我LG去打肝炎预防针，说小孩出生的几
个小时内得打第一针预防
针，期间各种血液体液样... 阅读全帖 |
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