c**i
发帖数: 6973 | 1 (1) You say, "现在在国内."
Sorry, there is NOTHING anybody can do, now that the patient--er, the dog--
is in China. Say what you may, but China is no place to treat human or
animal patients.
(2) Jack Daniel Terrier
http://en.wikipedia.org/wiki/Jack_Russell_Terrier
(Originating in the early 19th century from dogs bred and used by Reverend
John Russell, it has similar origins to the modern Fox terrier)
(3) Google with the term (Jack Daniel Terrier spine)--not quotation marks--
and you will find many ow... 阅读全帖 |
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l**********1
发帖数: 5204 | 2 The corresponding author of below Barcelona one PhD thesis (2009)
its reference list CNS only limited:
link:
//www.tesisenred.net/bitstream/handle/10803/7182/tjsc.pdf?sequence=1
i.e.
M.Reza Ghadiri, Ph.D
//www.ncbi.nlm.nih.gov/pubmed/19520909
and
//www.ncbi.nlm.nih.gov/pubmed/19566101
J Am Chem Soc. 2009 Jul 8;131(26):9368-
Universal translators for nucleic acid diagnosis.
Picuri JM, Frezza BM, Ghadiri MR.
Source
Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines R... 阅读全帖 |
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l**********1
发帖数: 5204 | 3 The corresponding author of below Barcelona one PhD thesis (2009)
its reference list CNS only limited:
link:
//www.tesisenred.net/bitstream/handle/10803/7182/tjsc.pdf?sequence=1
i.e.
M.Reza Ghadiri, Ph.D
//www.ncbi.nlm.nih.gov/pubmed/19520909
and
//www.ncbi.nlm.nih.gov/pubmed/19566101
J Am Chem Soc. 2009 Jul 8;131(26):9368-
Universal translators for nucleic acid diagnosis.
Picuri JM, Frezza BM, Ghadiri MR.
Source
Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines R... 阅读全帖 |
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a*****s
发帖数: 838 | 7 Can anybody help to get these two papers today, many thanks! contact z*****[email protected], thanks!
===first one===
pubmed link: http://www.ncbi.nlm.nih.gov/pubmed/19729489
Pkd2 dosage influences cellular repair responses following ischemia-
reperfusion injury.
Prasad S, McDaid JP, Tam FW, Haylor JL, Ong AC.
Am J Pathol. 2009 Oct;175(4):1493-503. Epub 2009 Sep 3.PMID: 19729489 [
PubMed - indexed for MEDLINE]
===another one===
Aberrant regulation of planar cell polarity in polycystic kidney disease. |
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c*******c
发帖数: 93 | 8 求pdf文章
http://www.ncbi.nlm.nih.gov/pubmed/19732307
J Sex Med. 2009
Nov;6(11):3063-70. Epub 2009 Sep 1.
Sexual dysfunctions and suicidality in patients with bipolar disorder and
unipolar depression.
Dell'Osso L, Carmassi C, Carlini M, Rucci P, Torri P, Cesari D, Landi P,
Ciapparelli A, Maggi M.
Psychiatry Unit, Department of Psychiatry, Neurobiology, Pharmacology and
Biotechnology, University of Pisa, Pisa
56100, Italy.
http://www.ncbi.nlm.nih.gov/pubmed/20712747
Bipolar Disord. 2010 Aug;12(5):45... 阅读全帖 |
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j*****d
发帖数: 787 | 9 this one may be not right.
i guess they two share the same name Zhao Chen.
One is working in Tianjin, another one working in Nanjin.
Correct me if I am not right. and I will delet this post.
4: Zhao C, Bellur DL, Lu S, Zhao F, Grassi MA, Bowne SJ, Sullivan LS, Daiger
SP,
Chen LJ, Pang CP, Zhao K, Staley JP, Larsson C. Autosomal-dominant retinitis
pigmentosa caused by a mutation in SNRNP200, a gene required for unwinding
of
U4/U6 snRNAs. Am J Hum Genet. 2009 Nov;85(5):617-27. Epub 2009 Oct 29.
P... 阅读全帖 |
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a*******e
发帖数: 245 | 10 Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
这个是preview，不能算吧
PubMed
and
Apr |
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l**********1
发帖数: 5204 | 11 EN T. P. Speed is Godfather in this field:
//www.ncbi.nlm.nih.gov/pubmed/11842121
or
//www.ncbi.nlm.nih.gov/pubmed/12925520
and
//www.ncbi.nlm.nih.gov/pubmed/20193046
cited his lab paper. |
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l**********1
发帖数: 5204 | 12 RE: 这些游来游去的蛋白是在细胞质里翻译的，还是在翻译的过程中先进入ER，然后转移出
来的？
CERT protein is localized on perinuclear regions
References:
a, JBC (2006)
htp://www.ncbi.nlm.nih.gov/pubmed/16895911
b, BBA (2007)
htp://www.ncbi.nlm.nih.gov/pubmed/17314061
c, Adv Exp Med Biol. 2010;688:1-23.
htp://www.ncbi.nlm.nih.gov/pubmed/20919643 |
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l**********1
发帖数: 5204 | 13 Good question!
Please try MIT 2011 degree thesis:
Phosphorylation-based control of cellular asymmetry and the cell
about
a birth scar protein called TipN
//dspace.mit.edu/handle/1721.1/68425
[PDF]
...
dspace.mit.edu/bitstream/.../768772324.pdf?
and 2010 one review article:
//www.ncbi.nlm.nih.gov/pubmed/20138002
and its relative Cell papers:
//www.ncbi.nlm.nih.gov/pubmed/16530048
//www.ncbi.nlm.nih.gov/pubmed/16530047 |
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l**********1
发帖数: 5204 | 15 //www.ncbi.nlm.nih.gov/pubmed/15903968
//www.ncbi.nlm.nih.gov/pubmed/19222862
//www.ncbi.nlm.nih.gov/pubmed/20725638
Ps: if you are satisfied with above links.
BAOZI 2 please transfer to my MITBBS account here. |
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l**********1
发帖数: 5204 | 16 做交叉学科的就整天被自个儿相轻 左脑轻右脑 右脑轻左脑? joke
BTW,
>一点实际作用都没有。。。
是吗?
//www.ncbi.nlm.nih.gov/pubmed/5861813
>Goodwin BC.
Oscillatory behavior in enzymatic control processes.
Adv Enzyme Regul. 1965;3:425-
Goodwin oscillator mathematic model 一点实际作用都没有?
then what is this:
//www.ncbi.nlm.nih.gov/pubmed/18703678
>
Transcriptional negative feedback loops are common throughout nature; introducing a time delay in such a
feedback loop can theoretically produce oscillatory pulses of gene expression (Goodwin 1965; x... 阅读全帖 |
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l**********1
发帖数: 5204 | 17 De rien.
plus
please go to
//www.ncbi.nlm.nih.gov/pubmed/22198840
for
The planarity of peptide bonds is an assumption that underlies decades of theoretical modeling of proteins
PNAS 2012 paper
but
Nonplanar peptide bonds in proteins are common and conserved but not biased toward active sites.
by Berkholz DS, Driggers CM, Shapovalov MV, Dunbrack RL Jr, Karplus PA.
Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):449-
and above paper 1st author his PubMed total records:
//www.ncbi.nlm.nih.gov/pubmed?... 阅读全帖 |
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l**********1
发帖数: 5204 | 18 嗯 更搞笑的是
PubMed
just frrom click the last author name at
//www.ncbi.nlm.nih.gov/pubmed/12953102
then
Results: 1 to 20 of 9430
//www.ncbi.nlm.nih.gov/pubmed?term=%22Wang%20W%22%5BAuthor%5D
OMG |
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l**********1
发帖数: 5204 | 19 only for paralogous
please go to
//www.ncbi.nlm.nih.gov/pubmed/15865991
its page one:
What is paralogy?
Since Darwin, for most biologists (or at least, for evolutionary biologists) homology has
come to mean something like ‘similarity due to common descent’, to distinguish it from
similarity due to convergent evolution. An accurate understanding of the relationships
between living things depends upon correctly identifying homologous characteristics of
an organism from other similarity. A classic ... 阅读全帖 |
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l**********1
发帖数: 5204 | 20 CMV 可以 试下
看图
from
//www.ncbi.nlm.nih.gov/pubmed/12052890
more papers:
//www.ncbi.nlm.nih.gov/pubmed/17823235
or
//www.ncbi.nlm.nih.gov/pubmed/16479005 |
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l**********1
发帖数: 5204 | 21 Continue to 18th floor
not only Plant but also human HIV treatment should take more care about
non coding RNAs:
References:
//www.ncbi.nlm.nih.gov/pubmed/22312265
more
//www.ncbi.nlm.nih.gov/pubmed?db=pubmed&cmd=link&linkname=pubmed_pubmed_
citedin&uid=15565159
original hint from:
http://www.mitbbs.com/article_t/Biology/31644341.html
NB: if HIV treatment is not relative to 抗性和kinase
Are you sure? centuribob (Planta)
回复]
[ 20 ]
发信人: centuribob (Planta), 信区: Biology
标 题: Re: 怎样设计小实验来确定一个基因编码的蛋... 阅读全帖 |
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l**********1
发帖数: 5204 | 22 Continue to 18th floor
not only Plant but also human HIV treatment should take more care about
non coding RNAs:
References:
//www.ncbi.nlm.nih.gov/pubmed/22312265
more
//www.ncbi.nlm.nih.gov/pubmed?db=pubmed&cmd=link&linkname=pubmed_pubmed_
citedin&uid=15565159
original hint from:
http://www.mitbbs.com/article_t/Biology/31644341.html
NB: if HIV treatment is not relative to 抗性和kinase
Are you sure? centuribob (Planta)
回复]
[ 20 ]
发信人: centuribob (Planta), 信区: Biology
标 题: Re: 怎样设计小实验来确定一个基因编码的蛋... 阅读全帖 |
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l**********1
发帖数: 5204 | 23 学习了
BTW
无论哪一个 Raman scatter or Stimulated emission
德国 哥廷根大 斯图加特大 都有牛人啊 除了法兰克福的Hell 以外
links:
//www.ncbi.nlm.nih.gov/pubmed/15884061
//www.ncbi.nlm.nih.gov/pubmed?db=pubmed&cmd=link&linkname=pubmed_pubmed_
citedin&uid=15884061
//www.pi3.uni-stuttgart.de/ags/volkmer/andreas.html |
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l**********1
发帖数: 5204 | 24 11th♂的细菌膜蛋白
>时间分辨常数大概在几秒到几十秒量级
那就是说细菌膜蛋白的铁离子通道 如果变化短于几秒 STORM无用武之地了吧?
打个比方用照相机 拍刘翔 百米跨栏的细节 想找到技术弱点 如可能改进后 伦敦奥运夺金牌
用傻瓜机的话是 南柯一梦吧 还得用D700 or MARKII 5D 吧
用电显的电子波长看不明白膜蛋白分子上的亚原子级别的实时动态变化的话
现实要看小于1.0 nm 的话
只有用 ESRF etc Synchrotron Radiation X-ray beam line
Freire F, Romão MJ, Macedo AL, Aveiro SS, Goodfellow BJ, Carvalho AL.
Preliminary structural characterization of human SOUL, a haem-binding protein.
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Jul 1;65(Pt 7):723-
Abstract
Human S... 阅读全帖 |
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l**********1
发帖数: 5204 | 25 学习了
BTW
无论哪一个 Raman scatter or Stimulated emission
德国 哥廷根大 斯图加特大 都有牛人啊 除了法兰克福的Hell 以外
links:
//www.ncbi.nlm.nih.gov/pubmed/15884061
//www.ncbi.nlm.nih.gov/pubmed?db=pubmed&cmd=link&linkname=pubmed_pubmed_
citedin&uid=15884061
//www.pi3.uni-stuttgart.de/ags/volkmer/andreas.html |
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l**********1
发帖数: 5204 | 27 Exactly,
now is Prigogine Dissipative Structures Theory its turn within
Cancer Stem Cell Stochastic Systems Biology fields.
References:
1)
//www.ncbi.nlm.nih.gov/pubmed/21203505
2)
//www.ncbi.nlm.nih.gov/pubmed/21867509
3)
//www.ncbi.nlm.nih.gov/pmc/articles/PMC2754594/
4)
//www.ncbi.nlm.nih.gov/pubmed/21727130
5)
//www.bio.ucalgary.ca/contact/faculty/huang.html
About
Ilya Prigogine Dissipative Structures Theory/Non-Equilibrium Stastistical Mechanics
please refer:
http://www.mitbbs.com/article... 阅读全帖 |
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l**********1
发帖数: 5204 | 28 以下的review
by
Shukla GC et al.
A boost for the emerging field of RNA nanotechnology.
ACS Nano. 2011 May 24;5(5):3405-18.
PubMed link:
//www.ncbi.nlm.nih.gov/pubmed/21604810
those CNS paper last/corresponding authorship s/he is your target. Sure
for example:
Lund K et al.
Molecular robots guided by prescriptive landscapes.(2010)
Nature 465:206-10.
//www.ncbi.nlm.nih.gov/pubmed/20463735
its corresponding authorship
Nils Walter
//www.umich.edu/~rnapeopl/WalterLabMember.htm
and his lab publicatio... 阅读全帖 |
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l**********1
发帖数: 5204 | 29 after quit Bio wet lab
if move into Biostatistics
may face ChIP-RNA Seq by Bayesian Statistical Techniques with R package
relative papers PubMed links:
//www.ncbi.nlm.nih.gov/pubmed/21245054
or
//www.ncbi.nlm.nih.gov/pubmed/22556370 |
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l**********1
发帖数: 5204 | 30 Bingo
plus one Chinese American super Bull in this field:
Frank Hu
Harvard Medical School
his group one paper:
Malik VS et al.(2010)
Sugar-sweetened beverages, obesity, type 2 diabetes mellitus, and
cardiovascular disease risk.
Circulation. 121: 1356-1364.
link:
//www.ncbi.nlm.nih.gov/pubmed/20308626
his lab publications link:
//www.hsph.harvard.edu/faculty/frank-hu/publications/
and PubMed all papers link:
//www.ncbi.nlm.nih.gov/pubmed?term=Hu%20FB%5BAuthor%5D&cauthor=true&cauthor_
uid=2030862... 阅读全帖 |
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l**********1
发帖数: 5204 | 31 if originally omitted below attached figure shown right pathway
then no way can bet below report:
Levy SF et al.(2012)
Bet hedging in yeast by heterogeneous, age-correlated expression of a stress
protectant.
PLoS Biol. 10: e1001325.
Abstract
Genetically identical cells grown in the same culture display striking cell-
to-cell heterogeneity in gene expression and other traits. A crucial
challenge is to understand how much of this heterogeneity reflects the noise
tolerance of a robust system and ho... 阅读全帖 |
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S**********l
发帖数: 3835 | 32 土了吧。pubmed现在也用的google的算法。
再说google有的pubmed未必有。pubmed有的，google都有。 |
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l**********1
发帖数: 5204 | 34 对头 没那么简单区分 对称还是 非对称
非对称的雌果蝇生殖干细胞的非对称作用的BMP蛋白的作用可能需要图林Reaction-
diffusion 偏微分公式方程组
来计算哦 而最后的结果可能是促成了成年雌果蝇的左右对称
pls refer;
Lu W at al. (2012)
Niche-associated activation of rac promotes the asymmetric division of
Drosophila female germline stem cells.
PLoS Biol. 10: e1001357.
Abstract
BACKGROUND:
Drosophila female germline stem cells (GSCs) reside adjacent to a cellular
niche that secretes Bone Morphogenetic Protein (BMP) ligands and anchors the
GSCs through adherens junctions. The GSCs divide a... 阅读全帖 |
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c********b
发帖数: 363 | 35 这种人还是有的，当然，可能正在找位置中或者已经找到了。比如不知道下面这个人找
到工作了没。
Jiang Xu,Hao-Dong Li,Li-Qing Chen,Yi Wang,Li-Li Liu,Liu He,and Wei-Hua WU* (
2006) A Protein Kinase, Interacting with Two Calcineurin B-like Proteins,
Regulates K+ Transporter AKT1 in Arabidopsis. Cell
http://www.ncbi.nlm.nih.gov/pubmed?term=chen%20li-qing%20sweet
Sucrose efflux mediated by SWEET proteins as a key step for phloem transport.
Chen LQ, Qu XQ, Hou BH, Sosso D, Osorio S, Fernie AR, Frommer WB.
Science. 2012 Jan 13;335(6065):207-11. Epub 2... 阅读全帖 |
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l**********1
发帖数: 5204 | 36 通俗点讲
Brain Tumor Cytoskeleton Dynamic Microtubules likes Tublin Myosin Action etc
. projects
要借助数学 和工程计算学 生化学
药学 医学 至少 5 个实验组的co-Fundings.
比如以下 生化数学计算方面的 论文
Margolin G. at al. (2012)
The mechanisms of microtubule catastrophe and rescue: implications from
analysis of a dimer-scale computational model
Mol Biol Cell. 23: 642-56.
link:
http://www.ncbi.nlm.nih.gov/pubmed/22190741
引用它的论文 是应用药学方面的
Bouazza N et al. (2011)
Population pharmacokinetics and pharmacodynamics of cysteamine in
nephropathic cy... 阅读全帖 |
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l**********1
发帖数: 5204 | 37 Please DIY from below papers:
a,
DNA Methylation Dynamics during In Vivo Differentiation of Blood and Skin
Stem Cells.
Bock C, Beerman I, Lien WH, Smith ZD, Gu H, Boyle P, Gnirke A, Fuchs E,
Rossi DJ, Meissner A.
Mol Cell. 2012 Aug 24;47(4):633-47. Epub 2012 Jul 26.
PMID: 22841485 [PubMed - in process]
b.
In vivo control of CpG and non-CpG DNA methylation by DNA methyltransferases.
Arand J, Spieler D, Karius T, Branco MR, Meilinger D, Meissner A, Jenuwein T
, Xu G, Leonhardt H, Wolf V, Walter J.... 阅读全帖 |
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l**********1
发帖数: 5204 | 40 楼主 如果 有推荐信 至少三封 包括master thesis main advisor etc her/his RL/
s.
可以试试 提前一年就 联系 近5～6年 已和cns 绝迹的 有志向称为 HHMI/ NAS 的
PI
尽管很久以前依靠末作的 名字和荣光 有过一作的 cns records.
目前紧缺cns的一作人选 吧
比如
Catherine A. Wolkow
2011 one paper:
HTTP ://www.ncbi.nlm.nih.gov/pubmed/21765926
lab link:
HTTP: //www.grc.nia.nih.gov/branches/lns/cvs/cwolkow.htm
当然今后靠楼主加盟 再出一 or N 篇 cns
要看楼主和那PI 的运气和造化了。
----
or NIDDK
John A. Hanover
his team 2010 one PNAS paper:
ncbi PubMed link:
HTTP: //www.ncbi.nlm.nih.gov/pubmed/20368426
... 阅读全帖 |
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l**********1
发帖数: 5204 | 41 GST-A.B co-expression pls let IPTG and the cultures were maintained at 4°C
for 48-72 h then do that induction
reference:
PMID 23525091
Production of soluble eukaryotic recombinant proteins in E. coli is favoured
in early log-phase cultures induced at low temperature. (2012).
Springerplus. 2:89.
FINDINGS:
A high yield of active soluble proteins was obtained by combining early-log
phase cultures and low temperatures for protein induction. When IPTG was
added at OD600 = 0.1 and cultures... 阅读全帖 |
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l**********1
发帖数: 5204 | 42 Here you go
about 50 bp of frog Xenopus sp BMP responsive element
firstly reported on
PMID 10660046
Cell 100: 229–240. (2000)
http://www.ncbi.nlm.nih.gov/pubmed/10660046
or PDF link:
HTTP: //xenopus.rockefeller.edu/publications/57.pdf
then by
Karaulanov E
Transcriptional regulation of BMP4 synexpression in transgenic Xenopus. (
2004).
EMBO J. 23: 844-56.
http://www.ncbi.nlm.nih.gov/pubmed/14963489
just recently
PMID 22984405
by
Javier AL et al.
Bmp indicator mice reveal dynamic regulation of tra... 阅读全帖 |
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l**********1
发帖数: 5204 | 44 BMJ
Gut is not trash journal
this journal 2013 one review
web link:
http://gut.bmj.com/content/62/8/1093.extract
its pp1094 left column top
cited here stuff sentence,
>Surprisingly, Yan et al did not provide
>Southern blot data demonstrating accumulation
of HBV DNA replication intermediates,
as this electrophoretic pattern is
a signature of productive virus replication.
Only one subfigure shows some evidence
of cccDNA formation, which
defines a successful infection by HBV;
however, unlike HBV DN... 阅读全帖 |
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