s*****g 发帖数: 87 | 1 Methylated CpG island里两条DNA链都被甲基化了。
请问有没有什么gene 或者 promoter上的 DNA 只有一条链能被甲基化? | l**********1 发帖数: 5204 | 2 here you go
PMID 20410883
Gao Z
An RNA polymerase II- and AGO4-associated protein acts in RNA-directed DNA
methylation. (2010).
Nature. 465: 106-9.
http://www.ncbi.nlm.nih.gov/pubmed/20410883
or
PMID 22895250
Zhang H, Zhu JK.
Seeing the forest for the trees: a wide perspective on RNA-directed DNA
methylation. (2012).
Genes Dev. 26: 1769-73.
http://www.ncbi.nlm.nih.gov/pubmed/22895250
or mammalian EStemCell mCXG
mCXG occurs asymmetrically with 98% of sites being methylated on only one
strand.
cited form
Non-CpG Methylation: Mechanisms, Dynamics and Implications
HTTP: //www.ucl.ac.uk/~ucbphca/work/Hywel_Carver_Case_Essay_Methylation.pdf
【在 s*****g 的大作中提到】![](/moin_static193/solenoid/img/up.png) : Methylated CpG island里两条DNA链都被甲基化了。 : 请问有没有什么gene 或者 promoter上的 DNA 只有一条链能被甲基化?
| s*****g 发帖数: 87 | | l**********1 发帖数: 5204 | 4 no thanks,
just learn each other!
【在 s*****g 的大作中提到】![](/moin_static193/solenoid/img/up.png) : 多谢大侠!!!
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