h********n
发帖数: 4079 | 1 我的意思是, 多数都是MALDI-TOF, 但我看到一个MS是Quadrupole TOF, 这个有啥特点
或者特别的原因要这样设计呢?
专业人士能不能给说说.
谢谢. | b*******g
发帖数: 1309 | 2 I bet what you mentioned is ESI-Q-TOF,
ESI-Q-TOF is similar as ESI-QqQ
TOF used here instead of Q is to improve mass accuracy.
QToF is much cheaper than FT MS, but the mass accuracy is also good (1-5ppm)
, and the scan speed is very fast, so it become more and more popular.
With the MALDI source, there is instrument called MALDI-ion trap-TOF,
produced by Shimadzu. Ion trap is used to select and fragment ions, then you
can do MS/MS or more.
There are also some home-made MALDI-quadrupole-TOF instruments, but not
popular, not commercial available instruments.
【在 h********n 的大作中提到】
: 我的意思是, 多数都是MALDI-TOF, 但我看到一个MS是Quadrupole TOF, 这个有啥特点
: 或者特别的原因要这样设计呢?
: 专业人士能不能给说说.
: 谢谢.
| h********n
发帖数: 4079 | 3 Thank you very much.
5ppm)
you
【在 b*******g 的大作中提到】
: I bet what you mentioned is ESI-Q-TOF,
: ESI-Q-TOF is similar as ESI-QqQ
: TOF used here instead of Q is to improve mass accuracy.
: QToF is much cheaper than FT MS, but the mass accuracy is also good (1-5ppm)
: , and the scan speed is very fast, so it become more and more popular.
: With the MALDI source, there is instrument called MALDI-ion trap-TOF,
: produced by Shimadzu. Ion trap is used to select and fragment ions, then you
: can do MS/MS or more.
: There are also some home-made MALDI-quadrupole-TOF instruments, but not
: popular, not commercial available instruments.
| b*****r
发帖数: 203 | 4 MALDI-TOF can only do MS, Quadrupole TOF can do MS/MS.
【在 h********n 的大作中提到】
: 我的意思是, 多数都是MALDI-TOF, 但我看到一个MS是Quadrupole TOF, 这个有啥特点
: 或者特别的原因要这样设计呢?
: 专业人士能不能给说说.
: 谢谢.
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