h********n 发帖数: 4079 | 1 我的意思是, 多数都是MALDI-TOF, 但我看到一个MS是Quadrupole TOF, 这个有啥特点
或者特别的原因要这样设计呢?
专业人士能不能给说说.
谢谢. | b*******g 发帖数: 1309 | 2 I bet what you mentioned is ESI-Q-TOF,
ESI-Q-TOF is similar as ESI-QqQ
TOF used here instead of Q is to improve mass accuracy.
QToF is much cheaper than FT MS, but the mass accuracy is also good (1-5ppm)
, and the scan speed is very fast, so it become more and more popular.
With the MALDI source, there is instrument called MALDI-ion trap-TOF,
produced by Shimadzu. Ion trap is used to select and fragment ions, then you
can do MS/MS or more.
There are also some home-made MALDI-quadrupole-TOF instruments, but not
popular, not commercial available instruments.
【在 h********n 的大作中提到】![](/moin_static193/solenoid/img/up.png) : 我的意思是, 多数都是MALDI-TOF, 但我看到一个MS是Quadrupole TOF, 这个有啥特点 : 或者特别的原因要这样设计呢? : 专业人士能不能给说说. : 谢谢.
| h********n 发帖数: 4079 | 3 Thank you very much.
5ppm)
you
【在 b*******g 的大作中提到】![](/moin_static193/solenoid/img/up.png) : I bet what you mentioned is ESI-Q-TOF, : ESI-Q-TOF is similar as ESI-QqQ : TOF used here instead of Q is to improve mass accuracy. : QToF is much cheaper than FT MS, but the mass accuracy is also good (1-5ppm) : , and the scan speed is very fast, so it become more and more popular. : With the MALDI source, there is instrument called MALDI-ion trap-TOF, : produced by Shimadzu. Ion trap is used to select and fragment ions, then you : can do MS/MS or more. : There are also some home-made MALDI-quadrupole-TOF instruments, but not : popular, not commercial available instruments.
| b*****r 发帖数: 203 | 4 MALDI-TOF can only do MS, Quadrupole TOF can do MS/MS.
【在 h********n 的大作中提到】![](/moin_static193/solenoid/img/up.png) : 我的意思是, 多数都是MALDI-TOF, 但我看到一个MS是Quadrupole TOF, 这个有啥特点 : 或者特别的原因要这样设计呢? : 专业人士能不能给说说. : 谢谢.
|
|