q****8
发帖数: 1 | 1 Does anyone know how to use drc package to estimate IC50? Which model is
normally used? I searched from internet that IC50 is the dose that
corresponds to half of the upper and lower limit of the curve, does that be
the same as ED50 if I use LL.3 in drc package?
I am confused about the definition of IC50 calculation. If a drug is very
resistant, normally the IC50 should be very high, however, if we use the
definition that IC50 is the dose response to half of the upper and lower
limit, it should be very small?
Thanks in advance. |
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