t*******d
发帖数: 1845 | 1 China automaker to open electric bus plant in CA
LOS ANGELES (AP) — A Chinese company whose mantra is Build Your Dreams
plans to build all-electric buses in California's Mojave Desert.
Lancaster Mayor R. Rex Parris and officials of BYD Automotive scheduled a
news conference Wednesday to announce plans to open the first Chinese-owned
vehicle manufacturing plant in the United States in the wind-swept high-
desert city 60 miles northeast of Los Angeles.
BYD, which opened its North American headquar... 阅读全帖 |
|
l**t
发帖数: 6971 | 2 【 以下文字转载自 SanFrancisco 讨论区 】
发信人: lopt (好好学习天天向上), 信区: SanFrancisco
标 题: 韩国两家航空公司的飞机千万不能坐！
发信站: BBS 未名空间站 (Sat Jul 13 03:05:44 2013, 美东)
这个是我在Yahoo News的comments看到的。一个在韩国两家航空公司教了五年的美国飞
行教官写的。基本就是讲，这两家公司的飞行员普遍不具备基本飞行技能，训练和考试
偷奸耍滑。摔飞机才是正常的。这次旧金山机场趁天气好维修自动助降的仪器，韩亚飞
行员就原形毕露了。
=====================================================
After I retired from UAL as a Standards Captain on the –400, I got a job as
a simulator instructor working for Alteon (a Boeing subsidiary) at Asiana.
When I first got ther... 阅读全帖 |
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D******e
发帖数: 11265 | 3 【 以下文字转载自 Stock 讨论区 】
发信人: lopt (好好学习天天向上), 信区: Stock
标 题: 韩国两家航空公司的飞机千万不能坐！ (转载)
发信站: BBS 未名空间站 (Sat Jul 13 03:06:23 2013, 美东)
发信人: lopt (好好学习天天向上), 信区: SanFrancisco
标 题: 韩国两家航空公司的飞机千万不能坐！
发信站: BBS 未名空间站 (Sat Jul 13 03:05:44 2013, 美东)
这个是我在Yahoo News的comments看到的。一个在韩国两家航空公司教了五年的美国飞
行教官写的。基本就是讲，这两家公司的飞行员普遍不具备基本飞行技能，训练和考试
偷奸耍滑。摔飞机才是正常的。这次旧金山机场趁天气好维修自动助降的仪器，韩亚飞
行员就原形毕露了。
=====================================================
After I retired from UAL as a Standards Captain on the –400, I got a job... 阅读全帖 |
|
e******t
发帖数: 3289 | 4 IF 3.4 分
Cell Physiol Biochem. 2013;31(1):113-22. doi: 10.1159/000343354. Epub 2013
Jan 25.
External Qi of Yan Xin Qigong inhibits activation of Akt, Erk1/2 and NF-&#
312;B and induces cell cycle arrest and apoptosis in colorectal cancer cells.
Yan X, Shen H, Jiang H, Hu D, Wang J, Wu X.
Source
Chongqing Institute of Traditional Chinese Medicine, Chongqing, China.
Abstract
Background/Aims: Colorectal cancer (CRC) is the second leading cause of
cancer death in the Western countries. Novel approac... 阅读全帖 |
|
z****0
发帖数: 3942 | 5 Are foods made using biotechnology safe to eat?
by Jonathan Strickland
Agricultural biotechnology is the science of using genes to alter crops. Why
would scientists want to fiddle with a plant's genes? The reasons range
from improving crop yields to designing plants that are resistant to pests
and disease. But are these genetically modified foods safe to eat?
The short answer is yes. Scientists around the world have conducted multiple
studies on genetically modified food and found that the food ... 阅读全帖 |
|
C*I
发帖数: 4736 | 6 Roundup® (a trade name used by Monsanto) and other herbicides based on
glyphosate (the generic name) are probably the most commonly applied weed
killers in use today. These herbicides are used by everyone from farmers to
foresters to gardeners to biologists trying to control invasive exotic
plants.
Glyphosate-based herbicides all work on the same biochemical principle --
they inhibit a specific enzyme that plants need in order to grow. The
specific enzyme is called EPSP synthase. Without tha... 阅读全帖 |
|
C*I
发帖数: 4736 | 7 所以说你不懂还要装？ 好了，给你说了中文，现在给你看看英文吧。 如果你看不懂
那我没有办法了。
Roundup® (a trade name used by Monsanto) and other herbicides based on
glyphosate (the generic name) are probably the most commonly applied weed
killers in use today. These herbicides are used by everyone from farmers to
foresters to gardeners to biologists trying to control invasive exotic
plants.
Glyphosate-based herbicides all work on the same biochemical principle --
they inhibit a specific enzyme that plants need in order to grow. The
spec... 阅读全帖 |
|
c*********l
发帖数: 3438 | 8 【 以下文字转载自 SanFrancisco 讨论区 】
发信人: honde (宏德之坚韧不拔), 信区: SanFrancisco
标 题: 诺贝尔奖获得者Sudhof老婆是踹了原配找美国老头的中国裔女留学(转载)
发信站: BBS 未名空间站 (Thu Oct 10 12:27:01 2013, 美东)
发信人: honde (宏德之坚韧不拔), 信区: Biology
标 题: 诺贝尔奖获得者Sudhof老婆是踹了原配找美国老头的中国裔女留学生ZZ
发信站: BBS 未名空间站 (Thu Oct 10 12:24:37 2013, 美东)
诺贝尔奖获得者Sudhof老婆是踹了原配找美国老头的中国裔女留学生
楼主：bxdfhbh 时间：2013-10-09 22:57:00 点击：3363 回复：32
新浪微博有人爆料，诺贝尔奖获得者Sudhof老婆是踹了中国原配找美国老头的中国
裔女留学生：
@walnut姐姐:他Lp和她的前lg是国内大学同学双飞，后来俩人经过奋斗成为某校ap
,那时她的前lg给她挂了很多文章。后来她搭上了sudhof,离婚又结婚又生女，然后就迅... 阅读全帖 |
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q******s
发帖数: 7469 | 9 【 以下文字转载自 WaterWorld 讨论区 】
发信人: honde (宏德之坚韧不拔), 信区: WaterWorld
标 题: 诺贝尔奖获得者Sudhof老婆是踹了原配找美国老头的中国裔女留学(转载)
发信站: BBS 未名空间站 (Thu Oct 10 12:24:52 2013, 美东)
发信人: honde (宏德之坚韧不拔), 信区: Biology
标 题: 诺贝尔奖获得者Sudhof老婆是踹了原配找美国老头的中国裔女留学生ZZ
发信站: BBS 未名空间站 (Thu Oct 10 12:24:37 2013, 美东)
诺贝尔奖获得者Sudhof老婆是踹了原配找美国老头的中国裔女留学生
楼主：bxdfhbh 时间：2013-10-09 22:57:00 点击：3363 回复：32
新浪微博有人爆料，诺贝尔奖获得者Sudhof老婆是踹了中国原配找美国老头的中国
裔女留学生：
@walnut姐姐:他Lp和她的前lg是国内大学同学双飞，后来俩人经过奋斗成为某校ap
,那时她的前lg给她挂了很多文章。后来她搭上了sudhof,离婚又结婚又生女，然后就迅
速得了... 阅读全帖 |
|
o*****k
发帖数: 169 | 10
要起诉就要有（1）有一定胜算概率, 或（2）逼和的把握。
Losing a case will create a direct precedence on point that will likely
remove all inhibitions for the exact kinds of behaviors intended to address
and proscribe in the very first place. |
|
J**b
发帖数: 182 | 11 addiction!
So every success person must be capable of anti-addictive, and they usually
have a large prefrontal cortex to inhibit their preliminary desire....haha |
|
b********n
发帖数: 38600 | 12 “America seems to have lost it's ability to differentiate between fair and
equal. If everyone has to abide by the same rules then that's fair. If
everyone gets punished or not punished the same amount in spite of breaking
the rules that's equal. Fair should be our goal not equal for making
everything equal inhibits those that will do more with the opportunities
given to them.”
of
combat
encourage
and |
|
c*******9
发帖数: 9032 | 13 www.teslamotors.com
All Our Patent Are Belong To You
By Elon Musk, CEO
Yesterday, there was a wall of Tesla patents in the lobby of our Palo Alto
headquarters. That is no longer the case. They have been removed, in the
spirit of the open source movement, for the advancement of electric vehicle
technology.
Tesla Motors was created to accelerate the advent of sustainable transport.
If we clear a path to the creation of compelling electric vehicles, but then
lay intellectual property landmines behi... 阅读全帖 |
|
g***j
发帖数: 40861 | 14 【 以下文字转载自 WaterWorld 讨论区 】
发信人: deer2005 (老鹿), 信区: WaterWorld
标 题: 依博拉病（Ebola virus disease）：真相和热点
发信站: BBS 未名空间站 (Sat Oct 4 13:08:03 2014, 美东)
依博拉病（Ebola virus disease）：真相和热点
博客文章：
http://www.mitbbs.com/pc/pccon.php?id=14439&nid=338895
几天来，由于在德州Dalas发现美国国内首例病例，Ebola成了人们谈论的热点话题，
Ebola相关生化药股也在爆涨中。
Ebola可怕么？它如何传播？如何预防和治疗Ebola？
这里讨论了一些关于Ebola的热点问题：
（一）Ebola的真相
世界卫生组织（WHO）列举的关于Ebola的关键事实：
1. Ebola virus disease (EVD), formerly known as Ebola haemorrhagic
fever, is a severe, often fatal illness in ... 阅读全帖 |
|
d********a
发帖数: 3698 | 15 Beijing, Aug 29: China’s first Ebola drug has recently obtained
manufacturing approval from the General Department of Logistics of Chinese
People’s Liberation Army (PLA) as a special medication for the PLA. The
drug named “JK-05″ is the country’s first drug for the treatment of the
deadly Ebola virus, and has been developed by the Institute of Microbiology
Epidemiology under Academy of Military Medical Sciences.
The research team in the institute, headed by Professor Wang Hongquan, spent
the las... 阅读全帖 |
|
x********i
发帖数: 905 | 16 Intel STS 2015 Finalists
Anandapadmanaban, Eswar
Dr. Ronald E. McNair Academic High School, Jersey City, NJ
The ThereNIM: A Touch-less Respiratory Monitor
Ashkin, Emily Lorin
Providence Day School, Charlotte, NC
A Novel Synergistic Approach for Enhancing Immunotherapy in the Treatment of
Melanoma
Chemparathy, Augustine George
Dougherty Valley High School, San Ramon, CA
Accumulation of the Biodiesel Precursor Triacylglycerol Offsets Oxidative
Stress in the Model Alga Chlamydomonas reinhardtii
Cui... 阅读全帖 |
|
g**1
发帖数: 10330 | 17 学霸又来：27岁女生成浙大教授、博导，5年前刚本科毕业
澎湃新闻记者 蒋子文
2015-02-26 07:40 来自 人事风向
27岁的陆盈盈已是教授、博士生导师、“青年千人计划”入选者，并将回到母校浙大全
职任教。
2月11日，千人计划网公示了第十一批“千人计划”青年人才名单，从去年8月
申报工作开始至今，经过三层筛选，最终这份名单中的667人通过了评审。
在这批引进的“海归”青年才俊中，共有41名“85后”，而其中最年轻的陆盈
盈则更是出生于1988年11月30日，堪称“学霸”。
中央2008年12月决定实施引进海外高层次人才的“千人计划”，该计划围绕国
家发展战略目标，用5到10年时间，在国家重点创新项目、重点学科和重点实验室、中
央企业和金融机构、以高新技术产业开发区为主的各类园区等，有重点的引进并支持一
批海外高层次人才回国（来华）创新创业。
千人计划网称，截至2014年5月底，“千人计划”已分十批引进4180余名海外高
层次人才。
5年前，陆盈盈才本科毕业。5年后，年仅27岁的她已是教授、博士生导师、“
... 阅读全帖 |
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j*****o
发帖数: 638 | 18 这位明显是搞炒菜的，一堆东西往锅里一丢，煮一煮，然后拿出来随便测一下，然后就
说是纳米新材料高性能，这些杂志都是超级水杂志，论研究意义不如生物，论理论水平
不如物理，论应用性更是屁都不是。
1. Y. Lu*, Z. Tu*, and L. A. Archer, Stable lithium electrodeposition in
liquid and nanoporous solid electrolytes, Nat. Mater. 13, 961-969, 2014. (*:
authors contributed equally to this work)
2. Y. Lu, S. K. Das, S. S. Moganty, L. A. Archer, Ionic liquid-nanoparticle
hybrid electrolytes and their application in secondary lithium-metal
batteries, Adv. Mater. 24, 4430-4435, 2012. This paper has been high... 阅读全帖 |
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m********5
发帖数: 17667 | 19 Khat消耗了该国的所有农田，40%的水用于浇灌Khat
Khat is so popular in Yemen, its cultivation consumes much of the country's
agricultural resources. An estimated 40% of the country's water supply goes
towards irrigating it,[14] with production increasing by about 10% to 15%
every year. One "daily bag" of khat requires an estimated 500 litres (130 US
gal) of water to produce.[15] Water consumption is so high, groundwater
levels in the Sanaa basin are diminishing, so government officials have
proposed relocating larg... 阅读全帖 |
|
O***O
发帖数: 1854 | 20 福布斯：中国政府偷偷抛售美金干预人民币汇率。从2014年Q4大约100亿美金一个月开
始，力度越来越大，目前达到1000亿美金一个月。
解读一下：目前央行名义外储3.7万亿，其中虚假QE成分（自己借钱给自己以印刷人民
币）大约8000亿，外债5000亿，坏账以及贬值（例如两房债）7000亿，也就是说实际外
储大约是1.7万亿。假设目前就是最坏的局面（i.e.国内不再宽松货币、股市不再狂飙
、出口不再萎缩），大约可以支持17个月，到2016年Q4。之前我估算说中共“谷支三年
”，按照福布斯的数据算乐观了。
====================
The People’s Bank of China, the central bank, and Chinese financial
institutions sold a net $25.2 billion in foreign exchange last month as they
defended the renminbi.
The month before, the currency was apparently running th... 阅读全帖 |
|
z**********e
发帖数: 22064 | 21 http://foreignpolicy.com/2015/06/25/korean-war-anniversary-why-
Beijing's support for Pyongyang during the Korean War tells us why it still
backs Kim today.
Sixty-five years ago, on June 25, 1950, the Soviet-equipped North Korean
army struck south of the 38th parallel. The ensuing three years of seesaw
warfare turned much of the Korean Peninsula into ashes: Up to 3 million
Koreans were killed or wounded before the two sides signed a cease-fire in
July 1953. Millions more were left to pick up pie... 阅读全帖 |
|
B*******c
发帖数: 5056 | 22 美国白宫承认美国现有的转基因食品作物管理体系不是以民众健康和生态安全为目标，
而是为孟山都和杜邦等极少数人的商业利益为目标;
承认现有体系的标准规范和管理质量不能确保法规要求的国家管理透明、危害风险预见
和应对。
-----------------------------------------------------------------
http://zhiyanle.blog.hexun.com/101722816_d.html
今年07月02日，美国白宫以科技顾问备忘录形式颁布了行政令，标题挺长：
MEMORANDUM FOR HEADS OF FOOD AND DRUG ADMINISTRATION， ENVIRONMENTAL
PROTECTION AGENCY， AND DEPARTMENT OF AGRICULTURE。
SUBJECT: Modernizing the Regulatory System for Biotechnology Products [1]。
[1] For the purpose of this memo， “biotechnology ... 阅读全帖 |
|
s****y
发帖数: 18685 | 23 【 以下文字转载自 Utah 讨论区 】
发信人: surely (雪里红◎内双), 信区: Utah
标 题: BYU女学生因被强奸被学校开除
发信站: BBS 未名空间站 (Wed May 4 10:56:27 2016, 美东)
A prominent Provo, Utah, police official has spoken out to PEOPLE against
Brigham Young University's practice of opening "honor code" investigations
into students who have reported being sexually assaulted, claiming the
practice inhibits victims from coming forward.
Controversy over the practice erupted last month when 20-year-old student
Madi Barney filed a Title IX complaint ... 阅读全帖 |
|
l*y
发帖数: 21010 | 24 http://www.youtube.com/watch?v=s59rx_VBCY8
One of those fucking awful black days
When nothing is pleasing and everything that happens
Is an excuse for anger
An outlet for emotions stockpiled, an arsenal, an armour
These are the days when I hate the world
Hate the rich, hate the happy
Hate the complacent, the TV watchers
Beer drinkers, the satisfied ones
Because I know I can be all of those little hateful things
And then I hate myself for realizing that
There's no preventative, directive or safe ... 阅读全帖 |
|
发帖数: 1 | 25 12月28日，答案 2 （2011）
Filariasis
From Wikipedia, the free encyclopedia
Filariasis
Life cycle of Wuchereria bancrofti, a parasite that causes filariasis
Classification and external resources
Specialty Infectious disease
ICD-10 B74
ICD-9-CM 125.0-125.9
Patient UK Filariasis
MeSH D005368
[edit on Wikidata]
Filariasis is a parasitic disease caused by an infection with roundworms of
the Filarioidea type.[1] These are spread by blood-feeding black flies and
mosquitoes. This disease belongs... 阅读全帖 |
|
f***y
发帖数: 4447 | 26 http://www.eepw.com.cn/article/201703/345450.htm
SEMICON China 2017开幕日即3月14日，上海微电子装备(集团)股份有限公司(后简称“
SMEE”)宣布，SMEE 与荷兰公司 ASML 签署战略合作备忘录(MoU)，为双方进一步的潜
在合作奠定了基础。
本文引用地址：http://www.eepw.com.cn/article/201703/345450.htm
根据这项合作备忘录，ASML 和 SMEE 将探索就 ASML 光刻系统的特定模块或半导
体行业相关产品进行采购的可能性。此次MoU的签署代表 ASML 继日前与上海集成电路
研发中心(ICRD)宣布合作之后，进一步深入参与中国的IC产业的发展。
光刻机被称为“人类最精密复杂的机器”，制造光刻机更被比作是在微观世界里“
造房子”——成像系统由几十个直径为200~300毫米的透镜组成，定位精度都是纳米级
。微米级的瞬时传输控制技术，犹如两架空客以1000/小时公里同步高速运动，在瞬间
对接穿针引线;玻璃镜面加工等精度，误差不会超过0.5毫米。
为了在更小的物理空间集... 阅读全帖 |
|
发帖数: 1 | 27 前面的答案其实不错，但貌似没有毒物分布和吸收的原理内容，那我就来献丑补充一下
吧。查了下书，书上是这么写的：
“体内和体外实验均表明，在机体各组织中，除肾脏外，肺组织中的百草枯浓度最高。
染毒30小时后，肺组织中百草枯的浓度会异常升高（Sharp等，1972；Rose等，1976）
。这是因为肺泡细胞中，有一个独特的二胺/多胺运载系统参与百草枯的摄取。百草枯
被摄取时，经NADPH依赖的单电子还原反应生成自由基，自由基与氧分子反应重新生成
百草枯阳离子和一个活性超氧化物阴离子，此超氧化物阴离子在超氧化物歧化酶作用下
转为过氧化氢。氧和过氧化氢可攻击多个未饱和脂质，形成脂质过氧化氢，再与不饱和
脂质反应形成更多的无脂质自由基，促进破坏性反应（Smith，1987）。肺泡细胞膜的
损坏可引起肺泡炎，破坏肺泡细胞，该处随即被成纤维细胞侵入，使肺组织弹性下降，
呼吸功能受损，气体（O2，CO2）无效交换。”
——Curtis D. Klaassen,《卡萨瑞特 道尔 毒理学》，人民卫生出版社,2005,P689
所以从这里来看，肺泡中的这个二胺/多胺运载系统是问题的关键。按照这个提示简单
搜索... 阅读全帖 |
|
t*******a
发帖数: 4055 | 28 SEMICON China 2017开幕日即3月14日，上海微装备(集团)股份有限公司(后简称“
SMEE”)宣布，SMEE 与荷兰公司 签署战略合作备忘录(MoU)，为双方进一步的潜在合作
奠定了基础。下面就随手机小编一起来了解一下相关内容吧。
根据这项合作备忘录，ASML 和 SMEE 将探索就 ASML 光刻系统的特定模块或行业
相关产品进行采购的可能性。此次MoU的签署代表 ASML 继日前与上海集成电路研发中
心(ICRD)宣布合作之后，进一步深入参与中国的IC产业的发展。
被称为“人类最精密复杂的机器”，制造光刻机更被比作是在微观世界里“造房子
”——成像系统由几十个直径为200~300毫米的透镜组成，定位精度都是纳米级。微米
级的瞬时传输控制技术，犹如两架空客以1000/小时公里同步高速运动，在瞬间对接穿
针引线;玻璃镜面加工等精度，误差不会超过0.5毫米。
为了在更小的物理空间集成更多的电子元件，单个电路的物理尺寸越来越小，主流
光刻机在硅片上投射的光刻电路分辨率达到50-90nm。超高的技术难度使得光刻机在全
世界集成电路设备厂商中形成... 阅读全帖 |
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W*****B
发帖数: 4796 | 29 现在美国情报部门火力全开。小黄人末日不远了！美华赶快准备收拾下去集中营的行李。
Don’t use Huawei phones, say heads of FBI, CIA, and NSA
The US intelligence community is still worried about Chinese tech giants’
government ties
The heads of six major US intelligence agencies have warned that American
citizens shouldn’t use products and services made by Chinese tech giants
Huawei and ZTE. According to a report from CNBC, the intelligence chiefs
made the recommendation during a Senate Intelligence Committee hearing on
Tuesday. The group i... 阅读全帖 |
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s******r
发帖数: 5309 | 30 4-way Stop sign 抢道，不让行人的大多是开好车的阔人。
In one experiment, the researchers stationed themselves at a busy
intersection with four-way stop signs and tracked the model of every car
whose driver cut off others instead of waiting their turn. People driving
expensive cars — like a brand-new Mercedes — were four times more likely
to ignore right-of-way laws than those in cheap cars like an old beat-up
Honda.
Next, they had a researcher play a pedestrian trying to cross at a crosswalk
and tracked which cars... 阅读全帖 |
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s******r
发帖数: 5309 | 31 2015年疮破大楼保安在大楼外殴打示威劳模致使一人重伤案，疮破和企业将作为被告之
一接受审判。
A New York state judge rebuffed President Trump’s attempt to distance
himself from a lawsuit against his security team on Monday, forcing him to
face claims that they allegedly attacked a group of peaceful Mexican
protesters in 2015.
Bronx Supreme Court Judge Fernando Tapia denied Trump’s motion to dismiss
allegations of assault and battery, destruction of property and negligent
hiring and supervising, saying that a jury could find that Trump “
aut... 阅读全帖 |
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l*****r
发帖数: 687 | 32 Ice is slightly different. Rather than enhancing flavours, it inhibits them
as the ice makes the temperature of the whisky drop rapidly. It is the same
as when you drink a good white wine that has been chilled down too much. It
will be a more refreshing drink and calm the burn of alcohol, but can make
the whisky taste dull and flat. The aromas and taste will only start to open
up and reveal their full characteristics once the whisky starts to warm up
to room temperature. |
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发帖数: 1 | 33 https://www.cnn.com/2019/11/03/health/china-alzheimers-drug-intl-hnk-scli/
index.html
好像是海草里一种多糖提取物，可以抑制肠胃的有害菌诱发的阿尔兹海默氏症
Sodium oligomannate therapeutically remodels gut microbiota and suppresses
gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer’s
disease progression
Article (PDF Available) in Cell Research 29(7):1-17 · September
2019 with 283 Reads |
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V*****2
发帖数: 7930 | 34 Inhibition of SARS Coronavirus
Infection In Vitro with Clinically
Approved Antiviral Drugs
Emily L.C. Tan,* Eng Eong Ooi,† Chin-Yo Lin,* Hwee Cheng Tan,†
Ai Ee Ling,‡
Bing Lim,* and Lawrence W. Stanton*
自己GOOGLE一下，这文章超过1MB，黏贴不上来。 |
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X*******G
发帖数: 14887 | 35 学者研究发现：瑞得西韦和磷酸氯喹能在体外有效抑制新冠病毒
近日，中国科学院武汉病毒研究所/生物安全大科学研究中心与军事科学院军事医学研
究院国家应急防控药物工程技术研究中心开展联合研究，在抑制2019新型冠状病毒（
2019-nCoV）药物筛选方面取得重要进展。相关研究成果以“Remdesivir and
chloroquine effectively inhibit the recently emerged novel coronavirus (2019
-nCoV) in vitro”（《瑞得西韦和磷酸氯喹能在体外有效抑制新型冠状病毒（2019-
nCoV）》）为题发表在中国自主知识产权的国际知名学术期刊Cell Research（《细胞
研究》）上。
该研究表明，在Vero E6细胞上，瑞得西韦（Remdesivir, GS-5734）对2019-nCoV的半
数有效浓度EC50=0.77 uM（微摩尔每升），选择指数SI大于129；磷酸氯喹（
Chloroquine）的EC50=1.13 uM，SI大于88，说明上述两种药物在细胞水平上能有效抑
制2019-nCoV的感染，其在... 阅读全帖 |
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S*******l
发帖数: 4637 | 36 找到了，是可以bind to ubiquitin ligase，最后结果是降低干扰素合成。
真狡猾。
J Virol. 2017 Mar 29;91(8). pii: e02143-16. doi: 10.1128/JVI.02143-16. Print
2017 Apr 15.
The Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Inhibits Type
I Interferon Production by Interfering with TRIM25-Mediated RIG-I
Ubiquitination. |
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k**********4
发帖数: 16092 | 37 1. We know what it is
The first cases of AIDS were described in June 1981 and it took more than
two years to identify the virus (HIV) causing the disease. With COVID-19,
the first cases of severe pneumonia were reported in China on December 31,
2019 and by January 7 the virus had already been identified. The genome was
available on day 10. We already know that it is a new coronavirus from group
2B, of the same family as the SARS, which we have called SARSCoV2. The
disease is called COVID-19. It ... 阅读全帖 |
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发帖数: 1 | 38 Biochem Biophys Res Commun. 2004 Oct 8;323(1):264-8.
In vitro inhibition of severe acute respiratory syndrome coronavirus by
chloroquine.
Keyaerts E1, Vijgen L, Maes P, Neyts J, Van Ranst M.
We report on chloroquine, a 4-amino-quinoline, as an effective inhibitor of
the replication of the severe acute respiratory syndrome coronavirus (SARS-
CoV) in vitro. ... |
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发帖数: 1 | 39 Virol J. 2005; 2: 69.
Published online 2005 Aug 22. doi: 10.1186/1743-422X-2-69
Chloroquine is a potent inhibitor of SARS coronavirus infection and spread
Martin J Vincent,1 Eric Bergeron,2 Suzanne Benjannet,2 Bobbie R Erickson,1
Pierre E Rollin,1 Thomas G Ksiazek,1 Nabil G Seidah,2 and Stuart T
Nicholcorresponding author1
Conclusion
Chloroquine is effective in preventing the spread of SARS CoV in cell
culture. Favorable inhibition of virus spread was observed when the cells
were either treated ... 阅读全帖 |
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发帖数: 1 | 40 源于中国的氯喹冠状病毒治疗
Original 雅美之途 雅美之途 2 days ago
位于法国南部马赛的世界领先传染病学家的最新研究表明，Hydroxychloroquine（羟氯
喹）与抗生素合用能够在六天内治愈新冠病毒。氯喹为临床常用药，所以不需要繁琐的
临床试验，川普总统迅速反应，强力推荐上临床。我都只是读到的法国人的论文手稿，
可见现在疫情的紧迫性。
总部位于瑞士巴塞尔的世界制药巨头Novartis宣布，自愿捐赠一亿三千万剂量的氯喹用
于全球抗新冠的治疗。在小样本的临床试验中取得了100%的治愈率后，现在是老药治新
病，激动人心！
这项临床应用的基础机理性研究最先是由Institute of Virology的前所长胡志红等领
导的团队与别人合作率先发表的。我同班同学为胡所长的夫君，我的老同学可能还贡献
了些思想，居然没有在原始论文里混到个署名，可见胡所长科学规范之严谨。这次疫情
告诉我们，与我们班联姻的群体素质都了得。我们男生娶武汉病毒所前所长，女士则嫁
现在几乎是世界名人的中南医院ICU主任彭志勇教授。
如果氯喹治疗成功，那将是近代中国医学领域里影响世界疾病治疗的新例子，... 阅读全帖 |
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W*****B
发帖数: 4796 | 42 Scientists Are Testing Nitric Oxide to Treat Coronavirus Patients
Scientists in Massachusetts, Italy, and elsewhere are experimenting with a
familiar medical treatment for the new problem of covid-19. They’ve begun
clinical trials meant to find out whether inhaled nitric oxide can save
people who are severely sick from the new coronavirus. This treatment might
even be used preventatively to keep health care workers infection-free.
Nitric oxide, or NO, is a key part of our biology (and not to be ... 阅读全帖 |
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g********d
发帖数: 4174 | 43 http://www.advocate.com/politics/2012/05/16/white-house-issues-
The White House on Tuesday threatened to veto the Violence Against Women Act
(VAWA) should protections for LGBT victims remain absent from the bill's
language.
The House version of the bill’s reauthorization “fails to include language
that would prohibit discrimination against LGBT victims in VAWA grant
programs,” according to a White House Statement of Administration Policy (
SAP) that lists other perceived major flaws, including t... 阅读全帖 |
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D**S
发帖数: 24887 | 44 大家可以按照这个适当关注下。
不知道是否还有其他州会加入这个不名誉的名单。
http://gma.yahoo.com/arizona-5-other-states-considering-anti-ga
Arizona Gov. Jan Brewer said a bill that would have allowed business owners
to refuse service to gay people and others on the basis of religious beliefs
was divisive and created more problems than it solved.
Brewer vetoed Senate Bill 1062, also known as the "Religious Freedom
Restoration Act," last night.
"Let's turn the ugliness of the debate over Senate Bill 1062 into a renewed
search for grea... 阅读全帖 |
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w****n
发帖数: 25644 | 45 【 以下文字转载自 Military 讨论区 】
发信人: Bluemusic (Bluemusic), 信区: Military
标 题: 转基因：美国认错了。
发信站: BBS 未名空间站 (Tue Aug 25 14:03:49 2015, 美东)
美国白宫承认美国现有的转基因食品作物管理体系不是以民众健康和生态安全为目标，
而是为孟山都和杜邦等极少数人的商业利益为目标;
承认现有体系的标准规范和管理质量不能确保法规要求的国家管理透明、危害风险预见
和应对。
-----------------------------------------------------------------
http://zhiyanle.blog.hexun.com/101722816_d.html
今年07月02日，美国白宫以科技顾问备忘录形式颁布了行政令，标题挺长：
MEMORANDUM FOR HEADS OF FOOD AND DRUG ADMINISTRATION， ENVIRONMENTAL
PROTECTION AGENCY， AND DEPARTMENT OF AGRICULT... 阅读全帖 |
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l****z
发帖数: 29846 | 46 一项对同性恋人群的研究发现，女同性恋父母的子女中58%是同性恋，男同性恋子女是
33%，异性恋父母子女是5-10%；欢迎同性恋的社区里同性恋比例高89%
http://www.aolnews.com/science/article/study-gay-parents-more-likely-to-have-gay-kids/19668089
Study: Gay Parents More Likely to Have Gay Kids
Updated: 1 day 19 hours ago
Paul Kix
AOL News
(Oct. 17) -- Walter Schumm knows what he's about to do is unpopular: publish
a study arguing that gay parents are more likely to raise gay children than
straight parents. But the Kansas State University family studies professor
has a ... 阅读全帖 |
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l****z
发帖数: 29846 | 47 http://www.christiangunowner.com/christian-blog.html#Liberals-J
I just read a web page on a site of an organization that represents public
workers. On that page this statement is made: "It's time for politicians to
create jobs instead of playing politics."
If I were in that organization, I would seriously consider getting out. That
statement is a common one that is parroted, primarily by liberals, across
America.
Here's the reality. If you've been around any time at all and paid any
attention to... 阅读全帖 |
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l****z
发帖数: 29846 | 48 By Richard Baehr
The Obama administration wants to "pivot" to jobs. A bit late, I would say.
They wasted a year pushing health care reform. That passed with zero
Republican votes in the House and Senate, and about the same number of
Republican ideas. When the Democrats controlled both branches of Congress
and the White House, they shoved their approach down the throats of
Republican in Congress, and an American public that opposed it then, and
still opposes the legislation by a 3-to-2 margi... 阅读全帖 |
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l****z
发帖数: 29846 | 49 The End of the Euro?
by Bruce Thornton (Research Fellow and W. Glenn Campbell and Rita Ricardo-
Campbell National Fellow, 2009–10, 2010–11)
Good riddance to a bad idea.
The champions of the European Union once touted it as a “bold new
experiment in living” and “the best hope in an insecure age.” But these
days “fear is coursing through the corridors of Brussels,” as the B.B.C.
reported in September. Such fear is justified, for the nations of Europe are
struggling with fiscal problems that challe... 阅读全帖 |
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l****z
发帖数: 29846 | 50 David and Charles Koch have been the targets of a campaign of vituperation
and assault, choreographed from the very top.
By THEODORE B. OLSON
How would you feel if aides to the president of the United States singled
you out by name for attack, and if you were featured prominently in the
president's re-election campaign as an enemy of the people?
What would you do if the White House engaged in derogatory speculative
innuendo about the integrity of your tax returns? Suppose also that the
president... 阅读全帖 |
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