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全部话题 - 话题: interferon
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S*******l
发帖数: 4637
1
来自主题: Military版 - 二更的老婆感染更严重了...
找到了,是可以bind to ubiquitin ligase,最后结果是降低干扰素合成。
真狡猾。
J Virol. 2017 Mar 29;91(8). pii: e02143-16. doi: 10.1128/JVI.02143-16. Print
2017 Apr 15.
The Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Inhibits Type
I Interferon Production by Interfering with TRIM25-Mediated RIG-I
Ubiquitination.
k**********4
发帖数: 16092
2
来自主题: Military版 - Coronavirus - ten reasons not to panic
1. We know what it is
The first cases of AIDS were described in June 1981 and it took more than
two years to identify the virus (HIV) causing the disease. With COVID-19,
the first cases of severe pneumonia were reported in China on December 31,
2019 and by January 7 the virus had already been identified. The genome was
available on day 10. We already know that it is a new coronavirus from group
2B, of the same family as the SARS, which we have called SARSCoV2. The
disease is called COVID-19. It ... 阅读全帖
w*l
发帖数: 14
3
信源:自由亚洲电台|编辑:2014-02-05
香港中文大学最近的一项研究显示,由于某种特定基因的影响,中国人比较容易感染
H7N9禽流感,此种疾病可能只会在中国人之间传播。
这项发表在《临床传染病》(Clinical Infectious Diseases)期刊的研究表明,因为中
国人身上带有“干扰素引导跨膜蛋白3”(Interferon-Induced Transmembrane
Protein3,IFITM3)这种易感基因(susceptibility gene),H7N9禽流感容易在中国人之
间传播,感染此种疾病的中国人也比较多。
香港中文大学传染疾病专家许树昌(David Hui)表示,IFITM3基因会增加流感的严重性
,普遍存在中国人身上,而白人很少有这种基因,这或可说明为何有较多中国人感染
H7N9禽流感。
许树昌在谈论H7N9禽流感的危险因素时说,最近的研究揭示,70%曾罹患严重流感的中
国病人拥有IFITM3基因,这或可解释为何家族成员容易集体感染。
他说,此种基因致使严重流感的风险增6倍,也会导致更高的流感死亡率。由于中国人
多有这种基因,中国人口感染的人群归因危... 阅读全帖
A********e
发帖数: 354
4
【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时,深深的鄙视一下自己的无聊行径!!
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖
b********s
发帖数: 9
5
Postdoctoral and Technician Positions in the Dinshaw J. Patel lab
in the Department of Biology, SUSTC, Shenzhen.
Dinshaw J. Patel is a member of the United States National Academy of
Sciences. The Patel structural biology lab is set to open on March 1, 2016
in the Department of Biology at the South University of Science and
Technology of China (SUSTC) in Shenzhen. SUSTC, located in picturesque and
environmentally healthy Shenzhen, is a new University that aims to become a
world-leader in Science... 阅读全帖
C****l
发帖数: 143
6
文章比较长,而且是英文的,不过很有帮助
以前老有人在版上问美国有没有治癌症的药物,除了化学理疗外
现在有AstraZeneca的新药Iressa, 还没通过FDA药检,不过已经在PhaseIII试用阶段
对某些病人有奇迹般效果,虽然范围可能只有10-15%的人有效
而且一旦服用,就可能要服用终生,每年费用是3000$
研制这类药品的公司还有Genetech, Imclone等

the
we
Once
cancer
on
a
&
chemotherapy.
Cancer
interferon
no
s*********e
发帖数: 77
7
来自主题: Medicine版 - Re: 治疗乙肝的特效药
interferon (IFN)α
lamivudine
adefovir dipivoxil
all requires prescription and all are expensive.
p*****c
发帖数: 155
8
来自主题: Medicine版 - 乙肝的一个新药名字
老妈大三洋几年了
动了两次手术
开了tumor
最近又查出病毒高
于是转战吃lamivudine, interferon之类
她电话里和我说到又出了第三代新药
现在上海只有传染病医院有售,临床一年
她自己拼出来的叫
telbizubine
但是我google了一下不对
不知道有没有牛人帮忙看一下到底是什么新药
d********r
发帖数: 303
9
be sure to give good nutrition.
there is one therapy in nci. (check this: http://www.cancer.gov/newscenter/pressreleases/MelanomaGeneTherapy)
basically he used immune cells to attack melanoma and shows some progress.
his results have been published on science last year. however, it is
difficult to get this type of therapy in china. the only good news is, as i
mentioned, immune system does some time can control this type of cancer.
also, you may ask doctor for interferon or IL-2, they may also sh
t*******n
发帖数: 4445
10
来自主题: Medicine版 - 有关TB治疗 与否 的问题
Could be either false positive or latent TB. Interferon-γ release assay
test may help in distinguish them.
For GC application, people need a TB test, and those with ACTIVE TB must get
treatment. That's all.
F**********8
发帖数: 36
11
来美前已知携带乙肝病毒,但其他指标正常。最近体检发现情况不妙,两转氨酶(ALT,
AST)都超出正常范围,表面抗原(HBsAg)和e抗体(Anti-HBe)阳性,乙肝病毒DNA含量4*
10^6,显示病毒复制活动。心中焦虑。有两个问题诚心求教各位有经验的兄弟姐妹:
1. 我年纪不小了,正打算要小孩子,没想到节骨眼上来了这个问题捣乱。请问目前我
的情况,是不是要赶紧治疗,这两年不能考虑怀孕了?
2. 我在美国见医生的感觉不太好,家庭医生根本不懂那些指标。请问是否有必要回国
治疗?但似乎网上资料显示国内的治疗方法也与美国大同小异,不外乎抗病毒药如
lamivudine(拉米夫定)和adefovir,以及干扰素(interferon)。请问国内还有比较有
效的办法吗?
焦虑惶急中,请百忙中提供您的意见。多多感谢!!
f******I
发帖数: 769
12
来自主题: Medicine版 - 表哥乙肝大三阳

elevated AFP in patient with chronic hep b infection is concerning for
hepatocellular carcinoma, he might need a liver ultrasound, normally they
say if AFP is high the lesion should be more than 1cm, if there is any
lesions found on ultrasound, he'd need biopsy, then depends on the result
and number of lesions he might be suitable for chemo-embolization and
transplant,
don't know if his interferon was standard or pegylated, if he failed
pegylated INFa, then he might need to be switched to antiv
x******n
发帖数: 208
13
来自主题: Medicine版 - 表哥乙肝大三阳
Thank you for the response. Very helpful. Could you look up those new treatments for me? I
don't know what kind of interferon he used. I only remember his treatment is extremely expensive.
g***r
发帖数: 285
14

if it's idiopathic pulmonary fibrosis you are talking about, it's a chronic
and progressive disorder that with very poor prognosis, maybe interferon
would help, or maybe lung transplant,
g***r
发帖数: 285
15

management
Complications
very good answer, just few more things to add
1. you have to make sure the diagnosis is essential thrombocythemia, not
polycythemia vera, myelodysplastic syndrome, CML, or any others that have
high risk of converting to leukemia,
2. the patient is 62 yrs old, which would put him into high risk for
thrombotic events(whether to treat is based on thombotic risk rather than on
hemorrhagic risk), so he will need treatment,
3. interferon will reduce platelet counts, but is VE
q********m
发帖数: 3234
16
1. you have to make sure the diagnosis is essential thrombocythemia, not
polycythemia vera, myelodysplastic syndrome, CML, or any others that have
high risk of converting to leukemia,
这个要问一下,在国内做过骨髓穿刺,专家会诊,应该是算确诊的。
2. the patient is 62 yrs old, which would put him into high risk for
thrombotic events(whether to treat is based on thombotic risk rather than on
hemorrhagic risk), so he will need treatment,
考虑血栓了,好像也考虑动脉硬化,您能具体说说吗?
3. interferon will reduce platelet counts, but is VERY expensive and
g*****j
发帖数: 1211
17
来自主题: Medicine版 - 真心求助
Hepatitis b treatment depends on the stage of disease. Newly infected
patients are treated with anti-HBV immunoglobulin. Chronic infection
treatment depends on severity of liver damage. If minimal liver injury and
viral titer is low, patient is usually monitored. If infection is more
active, interferon alpha as well as several reverse transcriptase inhibitor
can be used (such as Iamiudine, adefovir, entecavir). In severe cirrhosis,
liver transplantation is the only treatment. The bottom lin
c*****b
发帖数: 164
18
来自主题: Medicine版 - 用药3年,乙肝病毒终为零
Congratulations.
Could we know what your HBV genotype is? and what the medication you are
taking? interferon? if so, any side effects? Thank you.
s********r
发帖数: 1
19
来自主题: Medicine版 - 母亲慢性乙肝,请求建议
这几种药在美国常用,属于一线药。
Pegylated interferon alpha a2
Entecavir
Tenofovir
我不知道他们的中文名。对不起!
h*****3
发帖数: 1461
20
来自主题: Medicine版 - 13岁儿童血小板偏高
帮我爸朋友咨询下,谢大家了。
下面是引用那位叔叔的话:
我儿13岁,去年感冒查血偶然发现血小板高,正常值为100-300,他为1300,我们马上在烟台住院
检查,做了几十项检查,包括融合基因RT-PCR、抗人球蛋白、染色体等都没发现明显异常,后初
步定义为原发性血小板增高症(即不明原因引起的症病都为原发性),国内目前没有针对性的药
物,只能用羟基脲(Hydroxycarbamide Tablets)和干扰素(Recombinant H uman Interferon a
Ib Injection),这两种药都是靠这两种药的副作用(即为能引起血小板下降)进行治疗,。去年
年底和今年初,我又去北京天津等各大医院作了相应检查,还是未检查出发病原因,天津一大夫
告知我盐酸阿那格雷(anagrelide hydrochloride,Agrylin)此药,但他没有给病人用过,因为
此药国内没引进,想让你打听一下象我儿这样的小孩在美国发病高不高(在国内很少),治疗和国
内一不一样,再就是这种药的疗效和副作用怎么样?
w**********9
发帖数: 242
21
乙肝 can be treated with interferon in combination of anti-viral drugs such
as entecavir and adefovir. some people can be cured.
肝硬化is no cure.
j****x
发帖数: 1704
22
来自主题: Medicine版 - 乙肝要马上治疗吗
慢性HBV携带者?
隔1-2周复查肝功能,同时定量HBV DNA并检测HBV血清学指标。然后就遵医嘱吧。慢性
乙肝治疗目前的guideline非常明确,没什么可纠结的,显然不必回国治疗。
抗病毒治疗可以考虑首先采用peg-interferon长效干扰素(有几点因素需要考虑),核
苷类抗病毒药物(Entecavir or Tenofovir)作为候选,根据具体情况选择用药。
不管怎么说,慢性乙肝患者需要积极治疗,毋庸置疑。
l*h
发帖数: 4124
23
来自主题: Medicine版 - hpv16型病毒 c1n1 感染
not a good serotype. i don't think interferon is very effective for HPV.
s*******2
发帖数: 1182
24
yes, your family can come over US .
b*******e
发帖数: 302
r******r
发帖数: 309
26
来自主题: Medicine版 - Intron A (Interferon alfa-2b Injection)
是不是处方药?
网上查了查,没得卖.
国内朋友想要.不知到能否买到?
B****J
发帖数: 586
27
来自主题: Medicine版 - Intron A (Interferon alfa-2b Injection)

国内怎么可能买不到?查(1)安福隆 (2)安达芬
N*********c
发帖数: 330
28
Ask your doctor to order a blood test called "Interferon-γ release assays".
It is more accurate and specific.
If this is negative then your PPD is false positive.
R******0
发帖数: 307
29
来自主题: NextGeneration版 - 求助:回国卡介苗的接种问题
同关心这个问题。
国内的儿医和结核病院医生都建议打,因为国内公众场合的结核杆菌太普遍存在了,有
一半成年人都感染过结核杆菌,但大多数人的抵抗力都抗住了,因为结核杆菌感染过的
95%人群是不发病的,余下5%免疫力低下的人群才成为结核病人,而婴幼儿就属于易感
人群。
孩子回美上学后,学校的体检部门能否遵循CDC关于卡介苗(BCG)已免疫人群采用TB
blood tests (interferon-gamma release assays or IGRAs)的方法来判断是否为结核
杆菌隐性感染/结核病的方式,从而避免小孩做TB皮试,X光,乃至避免被强迫服用半年
对幼小的肝肾副作用很大的抗生素。
请有经验的妈妈们聊聊
f**********n
发帖数: 246
30
Interferon-gamma release assays (IGRAs) is the blood test you need.
c*******u
发帖数: 12899
31
☆─────────────────────────────────────☆
tyxfxvv (tyxfx) 于 h 提到:
其实乙肝对成年人的威胁很低很低。高感染风险的是婴幼儿,好在现在有疫苗了,出生
时及时接种即可。乙肝妈妈现在都能生育,她们关心的问题已经是抗病毒服药期间能否
要宝宝了。下面四个part分别解释:
单独的乙肝病毒本身不会导致肝硬化乃至肝癌;
需要治疗的“小三”往往比“大三”难治,“大三”常常病情最轻;
成人共餐感染微乎其微;
乙肝不可以也可以治愈。
希望可以澄清一些误区。
Part 1,乙型肝炎病毒(HBV)介绍——HBV本身不会导致肝硬化乃至肝癌
毋庸置疑的血液传播,不是消化道传染病。即使是那些顽固坚持和感染者吃饭有危险要
分餐消毒的人,理由也是可能会通过口腔溃疡等进入血液而传染。
结构上,HBV分三层,一般只关心最外面两层。最外面的是表面抗原,其他不用看,单
看这一项,阳性即代表感染,阴性就是没有感染,阳性转阴性就代表最终治愈。中间的
是e抗原,感染者e抗原阳性基本等同于民间说的“大三”, e抗原阴性则是“小三”。
有抗原就有相应的抗体。乙肝五项检测... 阅读全帖
d*a
发帖数: 60
32
来自主题: NextGeneration版 - 孕十三周 确认HCV-RNA Positive
Bless 楼主
关于特效药方面,给你点鼓励。Gilead公司的全球首个口服治疗丙肝的药马上就上市了
(不用和干扰素一起使用),就14年。去年年底FDA批准的,这个药的好处是,口服12
周治愈率达到90%左右,复发的比率只有10%左右,比以前interferon注射连续52个星期
的好很多(干扰素注射的有效率只有40%左右,而且副作用巨大,复发率也极高)。
之前也有人提到genotype,这个也很重要,不同的genotype对药物的反应也不一样。如
果你是genotype 2和或者3,那么治愈的可能性就更大了。目前比较难治疗的是
genotype 1,这个在美国占到60-70%的丙肝病人,但是Gilead的药物的治愈率是达到90
%左右的,Genotype2和3,好几个公司目前研究的药物临床的治愈率都达到了100%.
不要太担心,过去两年丙肝的药物开发上有巨大的突破,不再像以前那样了。不过总体
来说还是要多注意肝的保护,不要熬夜,不要喝酒,饮食上也多注意就好了。等你看过
专科医生就应该能知道更多的信息了。祝宝宝健康,早日康复!
b***4
发帖数: 12
33
来自主题: Returnee版 - Job opportunity in Beijing
It’s by chance that I got to know the CEO of Kawin Technologies. Kawin is
an established Chinese domestic biotech company located in Beijing. It’s a
main local producer of Interferon alpha with annual sale over 100 million
RMB. The revenue is not significant by US standard, but it gives the company
a strong foothold and provides sufficient cash flow for new drug
development.
Kawin is looking for a veteran returnee as its head of new drug development.
Kawin’s main interest is protein therapeutics... 阅读全帖
p*******g
发帖数: 2976
34
【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时,深深的鄙视一下自己的无聊行径!!
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖
j***u
发帖数: 836
35
来自主题: Stock版 - 会让gild跌吗?
No. GILD's Sovaldi is part of it.
The news is on 8月27日. If it had been bad news for GILD, GILD price would
have already been hit down.
Not a bad news.
From many comments that I have read lately, for HVC market, the bigger
threat would come from MRK, but in 2H 2015 or later.
http://seekingalpha.com/article/2451415-gilead-earnings-forecas
"Regarding Hepatitis C, concerns have been raised regarding the market size,
competitors and patent vulnerability. I believe that it is now understood
that this ... 阅读全帖
d******5
发帖数: 4273
36
FDA clears Gilead hep C combo pill • 1:43 PM
The FDA approves Gilead Sciences' (GILD -0.3%)
Harvoni for the treatment of chronic hepatitis C
genotype 1 infection.
Harvoni is a combination of ledipasvir and
sofosbuvir. It is the first approved regimen that
does not require administration with interferon or
ribavirin.
This is the third HCV drug approved in the last 12
months. The agency cleared Janssen's (JNJ +0.3%)
Oysio (simeprevir) in November 2013 and Sovaldi in
December 2013.
z*********1
发帖数: 192
37
来自主题: Stock版 - GILD 4:30 ER
Gilead Sciences 3Q Rev $6.04B >GILDBY Dow Jones & Company, Inc.
— 4:05 PM ET 10/28/2014
Gilead Sciences Announces Third Quarter 2014 Financial Results
- Product Sales of $5.97 billion -
- Sovaldi Sales of $2.80 billion -
- Non-GAAP EPS of $1.84 per share -
- Revised 2014 Full Year Guidance - FOSTER CITY, Calif.--(BUSINESS WIRE)--
October 28, 2014--
Gilead Sciences, Inc. (GILD

Loading...


) announced today its results of operations for the quarter ended September
30, 2014. Total re... 阅读全帖
d******8
发帖数: 1972
38
http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm42
The U.S. Food and Drug Administration today approved Viekira Pak (ombitasvir
, paritaprevir and ritonavir tablets co-packaged with dasabuvir tablets) to
treat patients with chronic hepatitis C virus (HCV) genotype 1 infection,
including those with a type of advanced liver disease called cirrhosis.
Hepatitis C is a viral disease that causes inflammation of the liver that
can lead to reduced liver function, liver failure or liver canc... 阅读全帖
c*********4
发帖数: 13
39
来自主题: Stock版 - GILD 值得关注
Abbv的定位是跟sovaldi比,他要好一点因为不需要和peg-interferon alpha(副作用大
)连用,参见fda批的label
但是方便性上差点,所以价格稍便宜。
对于新一代的harvoni,Abbv目前批的确实不如所以价格便宜1000刀。但是这个市场是会
变化的,abbv的pipeline上的新东西也是往harvoni靠拢的,也不需要ribavirin。新的
战场会转向6到8个星期的治愈,achn在做这个。所以gild在短期内有绝对统治地位,但
是未来新的产品会给他的竞争压力越来越大。
s********e
发帖数: 209
40
来自主题: Stock版 - BIIB ER
from seeking alpha.
Biogen (NASDAQ:BIIB) Q1 results ($M): Total Revenues: 2,726.8 (+6.7%); Net
Product Sales: 2,309.4 (+6.3%).Net Income: 970.9 (+18.0%); Non-GAAP Net
Income: 1,049.4 (+16.6%); EPS: 4.43 (+26.9%); Non-GAAP EPS: 4.79 (+25.4%).
Key Product Sales: Tecfidera: 945.9 (+7.1%); Total Interferon (Avonex +
Plegridy): 670.4 (-11.1%); Tysabri: 477.0 (+3.1%); Eloctate: 107.7 (+100.9%).
我觉得是相当不错的earning.
Biogen (NASDAQ:BIIB): Q1 EPS of $4.79 beats by $0.32.Revenue of $2.73B (+7.1
% Y/Y) misses... 阅读全帖
s*******t
发帖数: 65
41
我自己知道晚了,白白挨了一针,还为会不会影响baby忧心忡忡!后来才听说有一种blood
test可以检查TB,放狗一搜,uscis网站上写得清清楚楚:从2009年1月1日开始,除了传统
的TST(即TB皮试)以外,applicant可以选择用抽血检查(interferon gamma release
assay (IGRA))代替TST,好处就是不用给你注射病毒,直接血液检查是否有TB 病毒.当然
,如果血液检查阳性,还是要去照X-RAY的.血检只是类似于TST的screening test.但是,
我听说对于打了BCG疫苗的人,90%多TST呈阳性,但是血检却是阴性.这对于孕妇很重要,
阴性就不用照X-RAY啦.当然,以上说法只是我道听途说,没有任何理论根据,至少不用挨
一针对于孕妇也是好的.还有24小时医生直接知道结果,无须applicant去看结果.最后一
点,血检的费用比TST贵,另外还是设备限制,所以不是所有移民体检医生都提供血检,要
打电话问清楚.
然后是copy的uscis网站上的有关规定,供参考:
To fulfill the requirement of the i
s*******t
发帖数: 65
42
来自主题: Immigration版 - 怀孕期间能做ppd test么?
我就白挨了一针.后来知道可以做血检.下面是我前段发的贴,给你附上,希望有帮助:
发信人: smellycat (nikki), 信区: Immigration
标 题: 人品贴: 需要485体检的孕妇现在可以选择TB test or blood test for TB
发信站: BBS 未名空间站 (Fri Apr 16 18:09:43 2010, 美东)
我自己知道晚了,白白挨了一针,还为会不会影响baby忧心忡忡!后来才听说有一种blood
test可以检查TB,放狗一搜,uscis网站上写得清清楚楚:从2009年1月1日开始,除了传统
的TST(即TB皮试)以外,applicant可以选择用抽血检查(interferon gamma release
assay (IGRA))代替TST,好处就是不用给你注射病毒,直接血液检查是否有TB 病毒.当然
,如果血液检查阳性,还是要去照X-RAY的.血检只是类似于TST的screening test.但是,
我听说对于打了BCG疫苗的人,90%多TST呈阳性,但是血检却是阴性.这对于孕妇很重要,
阴性就不用照X-RAY啦.当然,以上说
t*********1
发帖数: 418
43
来自主题: Immigration版 - Tuberculosis (TB) 体检
请问版上各位大侠,你们去做485的体检时,TB 有两种选择: Tuberculin Skin Test (
TBT) or an Interferon Gamma Release Assay (IGRA).请问各位是做的哪一种呢?在
CIVILSURGEON 那里真的可以进行选择吗,还是他们大部分只给做一种,没有选择,是
不是在预约是就得问清楚呢?谢谢!
y***8
发帖数: 134
44
On page 1 of I-693, there is an option called "Interferon Gamma Release
Assay (IGRA) test"
You can use "QuantiFERON®-TB gold test". It is easy for the doctor to
operate, but it could cost you $100-$200 more expensive in comparison with
the chest X-ray examination.
y***o
发帖数: 246
45
The only purpose of taking those medicines is to kill the mycobacterium tuberculosis (causative agent of TB), otherwise it is helpless to take such toxic cocktail medcines.
If your doctor is correct on that the antibody induced by BCG can only last for 8 years, then how to explain almost all chinese are TB positives at their age of >30? Will he assuming that all those chinese have dormant MT? My personal case is that I got two shots of BCG between 12 to 15, and TB positive at age of 31, my docto... 阅读全帖
f********0
发帖数: 1129
46
来自主题: Immigration版 - 再问下有关体检中的 TB test 的问题
之前发帖问过有关体检的事,因为最近在备孕,医生是在不知道这个月的结果之前不让
做 X-RAY的。所以我们想尽量不做。看到版上有人给出主意说TB 阳性之后可以直接要
求做血检,可是医生说不行,具体的经过是这样的,想问问版上的大侠们,医生说的是
对的吗?
今天下午做医生那看TB的结果,肯定是 POSITIVE啦!然后我们要求不做X-RAY,直接做
BLOOD TEST, 可是那个医生居然说即使做了BLOOD TEST,他也要在表上写上做了 TB
,而且要写上是 POSITIVE,我们表示很不理解,因为我们看到表上写的是:either a
Tuberculin Test (TST) or an Interferon Gamma Release Assay (IGRA) is
required for all applicants 2 years of age and older.
我们的意思是既然人家说了 either or 了,我们就可以只选血检的结果写上去,TB的
就不用写了。可是医生就是死活不同意。我们说之前你又没告诉我们可以选择直接血检
不用做TB,他就不吱声了,只是说现在已经这样了... 阅读全帖
l********d
发帖数: 443
47
来自主题: Immigration版 - [急]体检的具体问题请教
请问你说的那个TB test用验血代替,是说做Interferon Gamma Release Assay吗?
表上写它也是initial screening test,但是如果我以前TB阳性,那么是不是这个血检也是阳性,然后结果还是要X-ray
呢?

,
must
just
,
q*p
发帖数: 667
48
485体检时Skin Test阳性并不一定意味感染了结核杆菌
很多美国本土的医生言之凿凿的认为TB skin test 阳性的人感染了肺结核杆菌。即使X
-ray胸透结果是阴性。那些庸医也会认为那只是意味着细菌处于休眠状态。他们会要
求你吃药。用于杀死休眠状态的肺结核杆菌的药异烟肼对肝脏有很大的毒副作用。我承
认胸透结果并不能排除有潜伏肺结核菌的可能,但在没有确诊肺结核感染前就要求人吃
这些药,实在太不负责任。
如果你告诉医生皮试阳性是由于以前在中国打过BCG疫苗, 有点知识的医生会明白。可
也会有很多的医生不懂就会说是你有潜伏着的TB细菌,BCG疫苗5年后对皮试没有影响什
么的。所以我就结合CDC网站的介绍,最新的研究报道和我自身的经历来说说为什么那
些医生是不负责任的。
CDC (Centers for Disease Control and prevention) 网站介绍TB的检测和诊断时也
承认了BCG对skin test 的干扰, 血液检测比较可靠。“TB blood tests (interferon
-gamma release assays or IGRAs), un... 阅读全帖
D******D
发帖数: 1022
49
you should perform Interferon Gamma Release Assay (IGRA) test in the first
place
t**********8
发帖数: 404
50
来自主题: Immigration版 - 体检TB皮试可以用血检IGRA代替吗?
IGRA-interferon gamma release assay
和皮试一样的作用,你要是皮试阳性估计IGRA也是阳性。你的医生建议你做IGRA是因为
你皮试已经是阳性了,你每多注射一次tuberculin你的反应会更重,红肿的会更厉害。
最终还是要做x-ray。
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