Z******5 发帖数: 435 | 1 国内小地方做ap有段时间了,研究方向一直没有怎么确定,现在实验室主要做的方向是
蛋白修饰和信号通路,和以前phd期间做的transcription and epigenetic regulation
不太一样,很多东西做起来不太熟悉也很辛苦,都是东搞搞西搞搞,发两篇小破文章。
再这样下去就废掉了。
最近和老板商量了一下,觉得还是在自己比较熟悉的领域DNA epigenetic或者RNA
epigenetic上多下一些功夫,深挖一下。但觉得这两个领域传统研究的方法都已经比较
成熟了。感觉3D genome是一个比较新起的领域,现在跳进去应该还不算晚。就是不太
确定整个大方向是个真坑还是假坑?希望别跳到假坑里,欢迎有经验的大神指点一下。 |
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Z******5 发帖数: 435 | 3 原来课题是做miRNA,你说能有啥绝技,也愁呀。 现在就是想跳一个刚兴起的坑里,
搞点绝技。
之所以想选这个坑,就是因为自己对转录调控和表观遗传还算熟悉,ChIP-seq和RIP-
seq都做过,没啥问题。想在这个基础上往3D genome发展一下。目前担心的就是这个所
谓的空间结构本质上到底是真的存在(保守并确实用功能),还是不存在这回事(那么
长的染色体纯粹是随机碰到一起的,根本是杂乱无章,无序可言),现在那些文章只是
噱头或concept。 |
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发帖数: 1 | 4 那你是要做单细胞3D genome咯?
[在 Zifeng85 (Zifeng9527) 的大作中提到:]
:其实4D就是多了一个时间而已,比如胚胎发育的时间。本质上和3D好像没啥区别。我
是做肿瘤的,这个不考虑。我要考虑的是癌变的各个阶段的差异,或者异质性的肿瘤细
胞中的差异。 |
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c*********r 发帖数: 1312 | 5 多谢你之前的帖子介绍这方面的实验室,很有帮助。我了解一下看这方面水深不深。如
果有前途的话,我也许就做个独立课题,海胆早期胚胎发育细胞周期中的3D genome
dynamics。不知道这个topic够不够sexy?
人。 |
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n********b 发帖数: 27 | 6 There is an opening of a Research Specialist in a Center for Genomics in a
private university in southern California. The position is supported by the
hard money with good and full benefit/medical plans. The candidates with
strong background in molecular biology with a PhD in the life sciences or a
medical degree from China are strongly encouraged to apply. Please email
your CV to Dr. Wang at [email protected]/* */, if you are interested. Thanks! |
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发帖数: 1 | 7 做一些生物信息分析,一个问题:
很多project,NGS其实是看趋势、普遍的机制、全基因组的变化;传统的生物学是跑胶
杀老鼠,看单个的基因。
那么,现在的问题是,你做了NGS,看到了genome wide的变化,传统的生物学往往不买
账,非要你收敛到一两个具体的基因再次验证。
然而,生物如此复杂,往往是通过一个network发挥作用的,但是构建network,又是不
可能的任务,最后还是收敛到具体的一两个基因。
一个悖论。 |
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发帖数: 1 | 8 想积攒review为申请eb1做准备。
本人可以review生物信息和化学信息两个方向。生物信息可以是genomics, molecular
evolution, or cancer-related. 现在主要做molecular diagnosis, ML在基因或者医
疗方面的应用,medical imaging方面的也可以审。
我的OCID profile: https://orcid.org/0000-0002-2088-7142
谢谢! |
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R******d 发帖数: 1436 | 9 通常几千个个体,几十万个标记snp,要算出每个snp的效应。貌似这类数据有维度问题
,一般的机器学习和线性方程就做不了,需要先降维处理。但是Genomic selection领
域有一
系列bayes的方法能用这种数据估计出每个snp的效应。请问是怎么实现的?是有偏的吗
?还是只算这些snp之前效应的排序而不是真正的效应值?
谢谢。 |
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s****l 发帖数: 10462 | 11 有人愿意讨论这里面提及的测序技术吗?优缺点,可行性,第一手经验等等
这里面谁现在是赢家很清楚,但是可见的将来和更远的将来谁会赢?
http://cen.acs.org/articles/92/i33/Next-Gen-Sequencing-Numbers-
全文拷贝如下
试试看图能不能贴上
/1407973177171.jpg
/1408028636124.jpg
OVER STORY
Next-Gen Sequencing Is A Numbers Game
As technical and cost barriers fall, instrument firms move their systems
into research and clinical markets
By Ann M. Thayer
Department: Business
Keywords: instrumentation, gene sequencing, diagnostics, genomics, cancer
[+]Enlarge
09233-cover-Openercxd_17647969-690
A... 阅读全帖 |
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c********n 发帖数: 225 | 12 【记录历史】谁重复验证了NgAgo?
项目 结题
date: 2017年8月2日
updated: 2017年8月4日
Note2017080401: added a few notable reviews/summaries
---------------------------------------
- NBT retraction note:
http://www.nature.com/nbt/journal/v34/n7/full/nbt.3547.html#correction2
原文引用
“Retracted online 02 August 2017
We are retracting our study because of the continued inability of the
research community to replicate the key results in Figure 4, using the
protocols provided in our paper. In this figure we report that the
Natro... 阅读全帖 |
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发帖数: 1 | 13 http://theprepared.com/blog/no-the-2019-ncov-genome-doesnt-actually-seem-engineered-from-hiv/
2019-nCoV genome doesn’t really seem engineered from HIV
A group of bioinformaticians at two prestigious universities in Delhi, India
, published a preprint scientific manuscript on the bioRxiv preprint server
Friday has led many to speculate wildly that 2019-nCoV may have been
deliberately engineered using HIV protein sequences.
The paper, entitled “Uncanny similarity of unique inserts in the 2019-nCoV... 阅读全帖 |
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o*******w 发帖数: 2310 | 14 【 以下文字转载自 MoneyFriends 俱乐部 】
发信人: opiumsnow (谦虚使人进步), 信区: MoneyFriends
标 题: HGSI, GNOM or ROSG
发信站: BBS 未名空间站 (Thu Jan 26 15:19:24 2012, 美东)
If it feels like there's a little more activity and interest in Human Genome
Sciences (NASDAQ:HGSI), Rosetta Genomics Ltd. (NASDAQ:ROSG), and Complete
Genomics, Inc. (NASDAQ:GNOM), you're not crazy - there is. The fact that
GNOM, HGSI, and ROSG are all up big-time today is proof enough of that
sudden interest, but even on a more subjective level there's cl... 阅读全帖 |
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b****n 发帖数: 8 | 15 Address:
Email:
Cell phone:
Work phone:
Oct 28, 2013
Department of Homeland Security
USCIS Nebraska Service Center
P.O. Box 87103
Lincoln, NE 68501-7103
I-140 Immigration Visa Petition Under First Preference EB-1
Petitioner/Beneficiary: XX Z., Ph.D.
Category of Petition: Alien of Extraordinary Ability
Classification Sought: 203(b)(1)(A)
Nature of Submission: Original Submission
Dear Immigration Officer,
This letter is respectfully submitted in s... 阅读全帖 |
|
b****n 发帖数: 8 | 16 Address:
Email:
Cell phone:
Work phone:
Oct 28, 2013
Department of Homeland Security
USCIS Nebraska Service Center
P.O. Box 87103
Lincoln, NE 68501-7103
I-140 Immigration Visa Petition Under First Preference EB-1
Petitioner/Beneficiary: XX Z., Ph.D.
Category of Petition: Alien of Extraordinary Ability
Classification Sought: 203(b)(1)(A)
Nature of Submission: Original Submission
Dear Immigration Officer,
This letter is respectfully submitted in s... 阅读全帖 |
|
C*I 发帖数: 4736 | 17 相比较而言,石正丽的《Bat origin of human coronaviruses/蝙蝠是人类冠状病毒的
来源》是扎扎实实的抓蝙蝠,解剖蝙蝠,分离病毒,对比DNA,RNA后得出得结论。
请lobbock读一读,说一说,走两步!
http://virologyj.biomedcentral.com/articles/10.1186/s12985-015-0422-1
Review
Open Access
Published: 22 December 2015
Bat origin of human coronaviruses
Ben Hu, Xingyi Ge, Lin-Fa Wang & Zhengli Shi
Virology Journal volume 12, Article number: 221 (2015) Cite this article
Abstract
Bats have been recognized as the natural reservoirs of a large variety of
viruses. Special attention has ... 阅读全帖 |
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C*I 发帖数: 4736 | 19 一直在误导,现在还在误导。 说说明corona virus 不可以从蝙蝠直接传染给人,必须
经过一个中间宿体性的其它动物才能传染给人。所以,病毒发生后,就故意误导全国人
民去海鲜市场找证据,找其它野生动物的麻烦。 而且还是病毒所去找的,找完了还装
模做样化验呀,分离呀什么的。最后把责任全部推给了海鲜市场的动物。可是那种动物
,一直不敢说,说了其它相关已经在人就会去早那种动物监测。 所以压根不说,打马
虎眼。
事实上,早在2013 年,就是这个武汉病毒研究所,已经从来自云南的蝙蝠身上所携带
的corona virus中分离出第一株蝙蝠SARS类似样的冠状病毒的活病毒,其中就包含了类
似于S类型的基因。从而证实这株病毒能够使其接受和SARS病毒相同的受体,并能够感
染人的细胞。对此新发现,武汉病毒所还把它以武汉病毒研究所的英文简称命名“WIV1
”,以彰显这一发现的重要价值和属于自己第一个发现的巨大研究成果。这个成果刊载
于2013年11月的《自然》杂志。
就是说,从云南弄回来的这种蝙蝠所携带的类似于sars的 corona virus, 可以不经过
其它受体/宿体,而直接传染给人。 他们... 阅读全帖 |
|
C*I 发帖数: 4736 | 20 一直在误导,现在还在误导。 说说明corona virus 不可以从蝙蝠直接传染给人,必须
经过一个中间宿体性的其它动物才能传染给人。所以,病毒发生后,就故意误导全国人
民去海鲜市场找证据,找其它野生动物的麻烦。 而且还是病毒所去找的,找完了还装
模做样化验呀,分离呀什么的。最后把责任全部推给了海鲜市场的动物。可是那种动物
,一直不敢说,说了其它相关已经在人就会去早那种动物监测。 所以压根不说,打马
虎眼。
事实上,早在2013 年,就是这个武汉病毒研究所,已经从来自云南的蝙蝠身上所携带
的corona virus中分离出第一株蝙蝠SARS类似样的冠状病毒的活病毒,其中就包含了类
似于S类型的基因。从而证实这株病毒能够使其接受和SARS病毒相同的受体,并能够感
染人的细胞。对此新发现,武汉病毒所还把它以武汉病毒研究所的英文简称命名“WIV1
”,以彰显这一发现的重要价值和属于自己第一个发现的巨大研究成果。这个成果刊载
于2013年11月的《自然》杂志。
就是说,从云南弄回来的这种蝙蝠所携带的类似于sars的 corona virus, 可以不经过
其它受体/宿体,而直接传染给人。 他们... 阅读全帖 |
|
C*I 发帖数: 4736 | 21 Published: 30 October 2013
Isolation and characterization of a bat SARS-like coronavirus that uses the
ACE2 receptor
Xing-Yi Ge, Jia-Lu Li, Xing-Lou Yang, Aleksei A. Chmura, Guangjian Zhu,
Jonathan H. Epstein, Jonna K. Mazet, Ben Hu, Wei Zhang, Cheng Peng, Yu-Ji
Zhang, Chu-Ming Luo, Bing Tan, Ning Wang, Yan Zhu, Gary Crameri, Shu-Yi
Zhang, Lin-Fa Wang, Peter Daszak & Zheng-Li Shi
Nature volume 503, pages535–538(2013)Cite this article
Abstract
The 2002–3 pandemic caused by severe acute respirator... 阅读全帖 |
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c****t 发帖数: 19049 | 22 AN ORISON OF SONMI~451
On behalf of my ministry, thank you for agreeing to this final interview.
Please remember, this
isn’t an interrogation, or a trial. Your version of the truth is the only
one that matters.
TRUTH IS SINGULAR. ITS “VERSIONS” ARE MISTRUTHS.
… Good. Ordinarily, I begin by asking prisoners to recall their earliest
memories to provide a
context for corpocratic historians of the future. Fabricants have no
earliest memories,
Archivist. One twenty-four-hour cycle in Papa Song’s is i... 阅读全帖 |
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p*******r 发帖数: 59 | 23 Career Opportunities at JCVI Infectious Disease (8 Positions)
The PIs did not ask me to post here, I did this just in case someone is
looking for similar positions but did not see these, and I would be happy to
see some chinese fellows to come. All the PIs are very nice.
All listed at
https://careers.jcvi.org/careers/Careers.aspx
http://www.jcvi.org/
No. 1 & No. 2 Post-Doctoral Fellows
Job Responsibilities
JCVI is looking for two Post-Doctoral Fellows to join the Infectious Disease
Group in our ... 阅读全帖 |
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D*a 发帖数: 6830 | 24 Nature忘了它有一整本杂志都是这玩意儿了?
两年前Science发了一篇GWAS方法研究人类长寿相关基因分析的文章,一年后被说有技
术问题,假阳性,撤稿了,最近刚从Plos One发出来了。两年前就瞅了一眼结果,现在
看貌似大结论没变啊?还没细看,细看也看不懂。。。
http://www.nature.com/nature/journal/v487/n7408/full/487427a.ht
Scientists and journals must work together to ensure that eye-catching
artefacts are not trumpeted as genomic insights, says Daniel MacArthur.
When a study of the genomes of centenarians reported genetic variants
strongly associated with exceptional longevity1, it received widespread
media and publi... 阅读全帖 |
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a********h 发帖数: 245 | 25 转一个相关的博客:
http://www.michaeleisen.org/blog/?p=1179
Blinded by Big Science: The lesson I learned from ENCODE is that projects
like ENCODE are not a good idea
By Michael Eisen | Published: September 10, 2012
When the draft sequence of the human genome was finished in 2001, the
accomplishment was heralded as marking the dawn of the age of “big biology
”. The high-throughput techniques and automation developed to sequence DNA
on a massive scale would be wielded to generate not just genomes, but
refe... 阅读全帖 |
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g*********d 发帖数: 233 | 26 Genetic history of an archaic hominin group from Denisova Cave in
Siberia
David Reich, Richard E. Green, Martin Kircher, Johannes Krause,
Nick Patterson, Eric Y. Durand, Bence Viola, Adrian W. Briggs, Udo
Stenzel, Philip L. F. Johnson, Tomislav Maricic, Jeffrey M. Good,
Tomas Marques-Bonet, Can Alkan, Qiaomei Fu, Swapan Mallick, Heng
Li, Matthias Meyer, Evan E. Eichler, Mark Stoneking, Michael
Richards, Sahra Talamo, Michael V. Shunkov, Anatoli P. Derevi... 阅读全帖 |
|
o*****D 发帖数: 1563 | 27 U.S. Clears DNA Firm’s Acquisition by Chinese
The federal government has given national security clearance to the
controversial purchase of an American DNA sequencing company by a Chinese
firm.
The Chinese firm, BGI-Shenzhen, said in a statement this weekend that its
acquisition of Complete Genomics, based in Mountain View, Calif., had been
cleared by the federal Committee on Foreign Investment in the United States,
which reviews the national security implications of foreign takeovers of
America... 阅读全帖 |
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t*d 发帖数: 1290 | 28 http://www.genomeweb.com//node/980559?hq_e=el&hq_m=1103092&hq_l
----------------------------------------
A recent study by scientists at Yale University suggests that the actual
cost of sequencing may be much higher than some current estimates indicate
since those figures may not factor in the analysis costs that are necessary
for a successful sequencing project.
In the paper, published in Genome Biology last month, Yale's Mark Gerstein
and colleagues consider costs that weren’t taken into accou... 阅读全帖 |
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j*p 发帖数: 411 | 29 本人在wet lab里面做纯数据分析,for NGS data analysis, 简单介绍一些自己接触过
,并且觉得挺有用的工具,说的有点杂,权作抛砖引玉,还请不吝赐教。
Next-Gen sequencing(NGS)和现在正在发展的3rd-gen sequencing将会在生物学研究中
被越来越广泛应用。不管你信不信,反正我信了。一是基于实验成本的降低($1k
whole-genome sequencing is coming),越来越多的实验室可以操作;二是可以提供
相对low throughput experiment多的多的数据和信息,可以看到很多从前看不到的东
西;三是sequencer本身对测序的准确性正在逐渐提高,所以实验固有错误率降低;四
是各种算法的成熟应用,这使得很多由于实验产生的误差在出数据后通过对数据的分析
得以过滤。按照library preparation来分,NGS主要有DNA-seq和RNA-seq
DNA-seq is usually used as ChIP-seq to study transcription factor(TF)-DNA
bi... 阅读全帖 |
|
j*p 发帖数: 411 | 30 本人在wet lab里面做纯数据分析,for NGS data analysis, 简单介绍一些自己接触过
,并且觉得挺有用的工具,说的有点杂,权作抛砖引玉,还请不吝赐教。
Next-Gen sequencing(NGS)和现在正在发展的3rd-gen sequencing将会在生物学研究中
被越来越广泛应用。不管你信不信,反正我信了。一是基于实验成本的降低($1k
whole-genome sequencing is coming),越来越多的实验室可以操作;二是可以提供
相对low throughput experiment多的多的数据和信息,可以看到很多从前看不到的东
西;三是sequencer本身对测序的准确性正在逐渐提高,所以实验固有错误率降低;四
是各种算法的成熟应用,这使得很多由于实验产生的误差在出数据后通过对数据的分析
得以过滤。按照library preparation来分,NGS主要有DNA-seq和RNA-seq
DNA-seq is usually used as ChIP-seq to study transcription factor(TF)-DNA
bi... 阅读全帖 |
|
l**********1 发帖数: 5204 | 31 please go to
//evol.mcmaster.ca/cgi-bin/my_wrap/brian/evoldir/PostDocs/
then search web with key word:
Droso
match three
then click just one:
Postdoctoral Researcher in Drosophila Evolutionary Genomics
Potential start dates are between April 1 and July 1, 2012. Please
indicate the earliest start date you would consider.
Feel free to contact me with any questions (jpool (at) wisc.edu).
John Pool
Assistant Professor
Laboratory of Genetics
University of Wisconsin-Madison
jpool (at )wisc.edu
----
A... 阅读全帖 |
|
r*****m 发帖数: 3619 | 32 Results: 46
Select item 25597018
1.
Exome-wide Sequencing Shows Low Mutation Rates and Identifies Novel Mutated
Genes in Seminomas.
Cutcutache I, Suzuki Y, Tan IB, Ramgopal S, Zhang S, Ramnarayanan K, Gan A,
Lee HH, Tay ST, Ooi A, Ong CK, Bolthouse JT, Lane BR, Anema JG, Kahnoski RJ,
Tan P, Teh BT, Rozen SG.
Eur Urol. 2015 Jan 14. pii: S0302-2838(14)01396-7. doi: 10.1016/j.eururo.
2014.12.040. [Epub ahead of print]
PMID: 25597018 [PubMed - as supplied by publisher] Free Article
Related citations... 阅读全帖 |
|
A********e 发帖数: 354 | 33 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时,深深的鄙视一下自己的无聊行径!!
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
|
p*******g 发帖数: 2976 | 34 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时,深深的鄙视一下自己的无聊行径!!
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
|
O***n 发帖数: 13127 | 35 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时,深深的鄙视一下自己的无聊行径!!
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
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a********k 发帖数: 2273 | 36 花了一个小时,深深的鄙视一下自己的无聊行径!!
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branches in lamellipodia. Cell. 2008 Sep
5;134(5):828-42. PubMed PMID: 18775315; PubMed Central PMCID: PMC2570342.
Cai L, Makhov AM, Bear JE. F-actin... 阅读全帖 |
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p*******g 发帖数: 2976 | 37 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时,深深的鄙视一下自己的无聊行径!!
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
|
x****6 发帖数: 4339 | 38
The occurrence of concentrated pneumonia cases in Wuhan city, Hubei province
of China was first reported on December 30, 2019 by the Wuhan Municipal
Health Commission (WHO, 2020). The pneumonia cases were found to be linked
to a large seafood and animal market in Wuhan, and measures for sanitation
and disinfection were taken swiftly by the local government agency. The
Centers for Disease Control and Prevention (CDC) and Chinese health
authorities later determined and announced that a novel coro... 阅读全帖 |
|
G****a 发帖数: 10208 | 39 Illumina, Inc. (NASDAQ:ILMN) today announced the launch of its TruGenome
Undiagnosed Disease Test provided by the CLIA-certified, CAP-accredited
Illumina Clinical Services Laboratory (ICSL). This new service uses whole
human genome sequencing to assist physicians in identifying the underlying
genetic cause of a rare or undiagnosed disease. By providing physicians with
more comprehensive information from a single test, the service enables a
broader understanding of the genetic basis for disease.
... 阅读全帖 |
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m***e 发帖数: 490 | 40 都来做一下,就几分钟的样子,看看你回去高考还能不能考上
前5个和所谓标准答案一致的,我发包子
(2)
June 26, 2000 — the Human Genome(基因组) Project, a great $3 billion, 15-year task aimed at drawing the
genetic(遗传的) map of humans, is now more than 90 percent completed. The scientific and medical
communities(团体) are very excited about the chances genetic research provides for getting rid of diseases
and prolonging(延长) human life. But those communities and policy(政策) makers also are careful about the
scientific door they are opening as the project... 阅读全帖 |
|
y***k 发帖数: 40 | 41 终于有人忍不住下手了,可是到哪里找业务去喂饱这个巨兽呢
=================================================
SAN DIEGO & SHANGHAI--(BUSINESS WIRE)--Mar. 10, 2014-- Illumina, Inc. (
NASDAQ:ILMN) and WuXi PharmaTech (Cayman) Inc. (NYSE:WX), a leading
pharmaceutical, biotechnology, and medical device R&D outsourcing company
with operations in China and the United States, today announced that the
WuXi Genome Center has purchased an Illumina HiSeq X Ten sequencing system.
This new investment will enable WuXi’s clinical genomic ser... 阅读全帖 |
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发帖数: 1 | 42 【Filariasis
From Wikipedia, the free encyclopedia
Filariasis
Life cycle of Wuchereria bancrofti, a parasite that causes filariasis
Classification and external resources
Specialty Infectious disease
ICD-10 B74
ICD-9-CM 125.0-125.9
Patient UK Filariasis
MeSH D005368
[edit on Wikidata]
Filariasis is a parasitic disease caused by an infection with roundworms of
the Filarioidea type.[1] These are spread by blood-feeding black flies and
mosquitoes. This disease belongs to the group of d... 阅读全帖 |
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发帖数: 1 | 43 12月27日 为什么我要替中国辩护
我要替中国辩护,并不是因为我是一个中国人,而是因为我知道中国就和这世界上绝大
数的国家一样,虽然有很多丑陋的现象,但是他们是受害者。就
象这个犯罪集团里很多的人一样,他们来自各种种族,他们可能充当了工具,但他们不
是制造这一切,谋划这一切的人。虽然经常会暴露中国产品出现问题。但要知道中国是
世界工厂,他们只是打工者,他们只是按照各种雇主提供的配方来生产,他们并不知道
他们会产生怎样的后果。或者这些工人知道后果,但他们只是奴隶,他们又如何去改变
这一切? 所以,当我的调查不断往前推进的时候,不可避免地会涉及各国的企业,但
这并不表明是针对这个国家或这个国家的人民,而是针对一种社会现实和丑陋现象。就
拿菲律宾来说,菲律宾是一个犯罪猖獗的国家,有很多犯罪分子,但是菲律宾人民却是
这个集团的受害者,他们/她们被绑架,沦为了牺牲品,人体实验对象。一个日本人,
强奸上千名菲律宾女孩,却没有受到惩罚。以前我也提到过,有20个国家的名单,这20
个国家的人民其实都是受害者。现在他们把矛头对准中国,或许仅仅是因为我揭示了他
们图害世界人民的内幕,而我是一个中国人的缘... 阅读全帖 |
|
发帖数: 1 | 44 12月27日 为什么我要替中国辩护
我要替中国辩护,并不是因为我是一个中国人,而是因为我知道中国就和这世界上绝大
数的国家一样,虽然有很多丑陋的现象,但是他们是受害者。就
象这个犯罪集团里很多的人一样,他们来自各种种族,他们可能充当了工具,但他们不
是制造这一切,谋划这一切的人。虽然经常会暴露中国产品出现问题。但要知道中国是
世界工厂,他们只是打工者,他们只是按照各种雇主提供的配方来生产,他们并不知道
他们会产生怎样的后果。或者这些工人知道后果,但他们只是奴隶,他们又如何去改变
这一切? 所以,当我的调查不断往前推进的时候,不可避免地会涉及各国的企业,但
这并不表明是针对这个国家或这个国家的人民,而是针对一种社会现实和丑陋现象。就
拿菲律宾来说,菲律宾是一个犯罪猖獗的国家,有很多犯罪分子,但是菲律宾人民却是
这个集团的受害者,他们/她们被绑架,沦为了牺牲品,人体实验对象。一个日本人,
强奸上千名菲律宾女孩,却没有受到惩罚。以前我也提到过,有20个国家的名单,这20
个国家的人民其实都是受害者。现在他们把矛头对准中国,或许仅仅是因为我揭示了他
们图害世界人民的内幕,而我是一个中国人的缘... 阅读全帖 |
|
发帖数: 1 | 45 12月28日 仔细阅读以下文章
或许这些文章可以告诉你们孩子被伤害病毒的答案。
Astellas Pharma 应该和这些人体实验有莫大的关系!
Founded 2005; 11 years ago
Headquarters 2-5-1, Nihonbashi-Honcho, Chūō-ku, Tokyo 103-8411, Japan
Key people Yoshihiko Katakana
(President and CEO)
Filariasis
From Wikipedia, the free encyclopedia
Filariasis
Life cycle of Wuchereria bancrofti, a parasite that causes filariasis
Classification and external resources
Specialty Infectious disease
ICD-10 B74
ICD-9-CM 125.0-125.9
Patient UK Filariasis
MeSH ... 阅读全帖 |
|
k**********4 发帖数: 16092 | 46 Most of the ethical discussions related to genome editing center around
human germline editing. This is because changes made in the germline would
be passed down to future generations. The debate about genome editing is not
a new one but has regained attention following the discovery that CRISPR
has the potential to make such editing more accurate and even "easy" in
comparison to older technologies.
Bioethicists and researchers generally believe that human genome editing for
reproductive purpose... 阅读全帖 |
|
发帖数: 1 | 47 12月27日 为什么我要替中国辩护
我要替中国辩护,并不是因为我是一个中国人,而是因为我知道中国就和这世界上绝大
数的国家一样,虽然有很多丑陋的现象,但是他们是受害者。就
象这个犯罪集团里很多的人一样,他们来自各种种族,他们可能充当了工具,但他们不
是制造这一切,谋划这一切的人。虽然经常会暴露中国产品出现问题。但要知道中国是
世界工厂,他们只是打工者,他们只是按照各种雇主提供的配方来生产,他们并不知道
他们会产生怎样的后果。或者这些工人知道后果,但他们只是奴隶,他们又如何去改变
这一切? 所以,当我的调查不断往前推进的时候,不可避免地会涉及各国的企业,但
这并不表明是针对这个国家或这个国家的人民,而是针对一种社会现实和丑陋现象。就
拿菲律宾来说,菲律宾是一个犯罪猖獗的国家,有很多犯罪分子,但是菲律宾人民却是
这个集团的受害者,他们/她们被绑架,沦为了牺牲品,人体实验对象。一个日本人,
强奸上千名菲律宾女孩,却没有受到惩罚。以前我也提到过,有20个国家的名单,这20
个国家的人民其实都是受害者。现在他们把矛头对准中国,或许仅仅是因为我揭示了他
们图害世界人民的内幕,而我是一个中国人的缘... 阅读全帖 |
|
n*********4 发帖数: 99 | 48 NEW YORK (GenomeWeb News) – The federal budget for fiscal year 2014 that
the Obama Administration released yesterday includes a request for $31.3
billion to fund the National Institutes of Health, which would be an
increase of 1.5 percent over the budget it received in FY 2012, the last
year the government passed a complete budget. In the current fiscal year,
the government is funded under a continuing resolution that provided $30.8
billion for NIH.
The funding proposal in the White House plan d... 阅读全帖 |
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b********w 发帖数: 334 | 49 直接面向个人
Tech Details:
- FDA approved Saliva collection kit.
- Agilent SureSelect V5 50MB chip
- 75x on target coverage (after mapping, filtering, and duplicate removal,
130-140x raw throughput)
- 99% Coverage > 1x
- 90% Coverage > 20x
- CLIA certified Illumina sequencing.
Deliverable
- Ownership of your genome
- VCF file (Beta 期间你要原始数据 BAM,我们也可以提供。)
- CLINVAR, CGD summary about your variants
- Traits
- Beta 期间你要原始数据,我们也可以提供。
Public exposure
Genomeweb:
https://www.genomeweb.com/molecular-diagnost... 阅读全帖 |
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