f*********e
发帖数: 24 | 1 Relation between MeCP2 and Rett syndrome
1999-10 Nat Gen Huda Y. Zoghbi Rett syndrome is caused by mutations
in X-linked MECP2, encoding methyl-CpG-binding protein 2
Mouse models: whole-body knockout, brain-specific, brain-region-specific,
knock-in,..., over-expression, rescue, ...
2001-03 Nat Gen Adrian Bird A mouse Mecp2-null mutation causes
neurological symptoms that mimic Rett syndrome
2001-03 Nat Gen Rudolf Jaenisch Deficiency of methyl-CpG bindi... 阅读全帖 |
|
j*****d
发帖数: 787 | 2 http://the-scientist.com/2011/09/20/plant-rnas-found-in-mammals
+Plant RNAs Found in Mammals
MicroRNAs from plants accumulate in mammalian blood and tissues, where they
can regulate gene expression.
By Cristina Luiggi | September 20, 2011
11 Comments Link thisStumbleTweet thisDreamstime.com, Rewat
WannasukMicroRNAs from common plant crops such as rice and cabbage can be
found in the blood and tissues of humans and other plant-eating mammals,
according to a study published today in Cell Research.... 阅读全帖 |
|
v*****s
发帖数: 20290 | 3 【 以下文字转载自 Joke 讨论区 】
发信人: mutouhui (mutouhui), 信区: Joke
标 题: Re: 麻省科学家发现病毒克星“天龙”
发信站: BBS 未名空间站 (Sun Nov 13 19:08:54 2011, 美东)
http://web.mit.edu/press/2011/antiviral.html
New drug could cure nearly any viral infection
Researchers at MIT’s Lincoln Lab have developed technology that may someday
cure the common cold, influenza and other ailments.
CAMBRIDGE, Mass. — Most bacterial infections can be treated with
antibiotics such as penicillin, discovered decades ago. However, such drugs
are useless... 阅读全帖 |
|
O******e
发帖数: 4845 | 4 Severe Congenital Disorder Successfully Treated in a Mouse Model for the
First Time
http://www.sciencedaily.com/releases/2011/12/111222103044.htm
ScienceDaily (Dec. 22, 2011) Using a mouse model, Heidelberg University Ho
spital researchers have for the first time successfully treated a severe con
genital disorder in which sugar metabolism is disturbed. The team headed by
Prof. Christian Korner, group leader at the Center for Child and Adolescent
Medicine, demonstrated that if female mice are giv... 阅读全帖 |
|
l**********1
发帖数: 5204 | 5 （老印不懂中文，我代他发的）
我是一个老印。我们实验室是个中女PI
标 题: 今天陪老板去作孕检 结果出事了！
今天老板让我陪她去医院作孕检 医院还蛮远的 高速要开三四十迈
去的时候还好 孕检也蛮顺利的 回来的时候出事了
为了做一项血检 老板在医院喝了不少水
因为下午有seminar 老板没来得及上厕所 我们就往回开了
路上老板表情异样 我想是估计是要pee 就直接问了 老板的脸刷的就红了
我赶紧开了GPS找厕所 最近的还有20几迈
只好找了一个僻静的路边 我停下来 打了双闪
老板下车去路边林子解决问题了
万万没想到 一部警车pass by 以为我们车坏了好心 停下来问
我傻乎乎地说车没事 就是方便一哈
胖警察一个箭步就冲进林子 把老板拎出来了
还上了手铐！！！！！
胖警察说public urinating要罚五百块 外加一天jail time。
老板被拎上了警车后座
上车前幽怨地望了我一眼 -- 也可能是恶毒地。。。
我因为下午有seminar 只好先自己开车回学校了。
也不知道老板现在怎么样了
出来了没有。。。
#####
标 题: 老板放出来了。。。
我昨晚睡的还挺香的。。。
一... 阅读全帖 |
|
l**********1
发帖数: 5204 | 6 if by GFP not luciferase
you can try CAG (cytomegalovirus (CMV) early enhancer element and chicken
beta-actin) promoter
paper link:
//www.ncbi.nlm.nih.gov/pubmed/22378886
Mice strain link:
//jaxmice.jax.org/strain/016532.html
Description
The CAGs-rtTA3 transgene has a CAG (cytomegalovirus (CMV) early enhancer
element and chicken beta-actin) promoter driving widespread expression of
reverse tetracycline-controlled transactivator 3 (rtTA3). High rtTA3
expression is observed in most tissues examin... 阅读全帖 |
|
l**********1
发帖数: 5204 | 7 预先打了伏笔了哈 Wo Kao Nature News
Performance enhancement: Superhuman athletes
Enhancements such as doping are illegal in sport — but if all restrictions
were lifted, science could push human performance to new extremes.
Helen Thompson
18 July 2012
Code breaking
Gene doping — enhancing performance by adding or modifying genes — has
been the subject of locker-room gossip for the past ten years. There are
plenty of natural mutations for which to wish. The Finnish cross-country
skier Eero Mäntyrant... 阅读全帖 |
|
l**********1
发帖数: 5204 | 8 BGI or others just try
NGS with both blood samples Ye Shiwen and Katie Ledecky
plus below six athletes total 8 athletes
performance profiling”方法，将所有国际上
有名的现役游泳运动员的比赛成绩，进行profiling分析，发现最高分排名（也就是最
“anomalous”的排名）是：
1. Elizabeth Beisel
2. Michael Phelps
3. Rebecca Adlington
4. Ian Thorpe
5. Stephanie Rice
6. Allison Schmitt
while can find proof of her EPOR mutation which is identical to Finnish
cross-country skier Eero Mäntyranta
and also is different to former matchs any DNA samples Ge... 阅读全帖 |
|
|
l**********1
发帖数: 5204 | 10 LZ 要找个mentor lab 问下对方 啦
比如 Fan GP of UCLA:
Fouse, S. et al. and Fan, G. (2008)
Promoter CpG methylation contributes to ES cell gene regulation in parallel
with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation..
Cell Stem Cell 2: 160-169.
//faculty.bri.ucla.edu/institution/personnel?personnel_id=45766
and his group one N sister paper about DKO mice strain:
Feng J et al. and Fan G. (2010)
Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in
adult forebrain ne... 阅读全帖 |
|
s******9
发帖数: 283 | 11 http://www.cell.com/abstract/S0092-8674%2813%2900449-2
Researchers at the Harvard Stem Cell Institute (HSCI) have discovered a
hormone that holds promise for a dramatically more effective treatment of
type 2 diabetes, a metabolic illness afflicting an estimated 26 million
Americans. The researchers believe that the hormone might also have a role
in treating type 1, or juvenile, diabetes.
The work was published today by the journal Cell as an early online release.
It is scheduled for the May 9 pr... 阅读全帖 |
|
s******9
发帖数: 283 | 12 http://www.cell.com/abstract/S0092-8674%2813%2900449-2
Researchers at the Harvard Stem Cell Institute (HSCI) have discovered a
hormone that holds promise for a dramatically more effective treatment of
type 2 diabetes, a metabolic illness afflicting an estimated 26 million
Americans. The researchers believe that the hormone might also have a role
in treating type 1, or juvenile, diabetes.
The work was published today by the journal Cell as an early online release.
It is scheduled for the May 9 pr... 阅读全帖 |
|
w***a
发帖数: 432 | 13 这片文章里有讲过一点。和shRNA一样表达。
@Article{Chen2004,
Title = {MicroRNAs modulate hematopoietic lineage
differentiation.},
Author = {Chang-Zheng Chen and Ling Li and Harvey F
Lodish and David P Bartel},
Journal = {Science},
Year = {2004},
Month = {Jan},
Note = {mark},
Number = {5654},
Pages = {83--86},
Volume = {303},
Abst... 阅读全帖 |
|
r*****i
发帖数: 117 | 14 谢谢。
1. the percentage of B cell in PB is also increased, not check SPL yet.
2. mainly, immature B cell increased in my KO mice compared to age-matched
WT mice.
As for MZ B cell, FO B cell, and GC B cell, I did not checked it yet. I plan
to check pro-B, pre-B, pre-pro-B.
3. As for IgG, IgM, IgA, I did not check it yet. I can check it by ELISA.
4. I did not get your point. Some of my experimental result (mutual
transplantation assay) shows that B cell increase in response to this gene
deletion is ... 阅读全帖 |
|
s******y
发帖数: 28562 | 15 http://www.theverge.com/2014/4/28/5661118/lab-mice-fear-men-not
Lab mice fear men but not women, and that's a big problem for science
The history of science is one chock-full of mice and men. Historically,
biological and medical research has largely depended on rodents, which
provide scientists with everything from cells and organs to behavioral data.
That's why a new study in which researchers found that mice actually fear
men, but not women, has the potential to be so disruptive. It might mean... 阅读全帖 |
|
s********3
发帖数: 231 | 16 《科学》对STAP手稿的专家评审意见曝光
《科学》对传说中的STAP细胞论文的三名评审专家意见，过去一直被雪藏，今天终于
被曝光。专家对这一研究的评价不高，认为非常全面的描述性研究，如果结果确定，可
能导致发育生物学大厦的颠覆，其实是不相信这种研究结论。因为没有当时的投稿件，
所以没有办法对这些评价进行更深入分析。不过这些资料显然都在某个地方，只是拥有
的人不愿意拿出来。
Retraction Watch readers are of course familiarwith the STAP stem cell saga,
which was punctuated by tragedy last month whenone of the authors of the
two now-retracted papers in Nature committed suicide.
In June, Science‘s news section reported:
Sources in the scientific community confirm that early version... 阅读全帖 |
|
l****y
发帖数: 486 | 17 Assume your knock-in here refers to mutating a site at the endogenous locus
(thus over expression-type approach, such as making transgenic mouse from
Rosa26 locus, will not be applied here).
Then the question is: you expect your mutation is a gain-of-function
mutation or loss-of-function mutation.
If your mutation is GOF mutation, it is easy, see Kras V12 KI strategy--
basically insert stopper element LSL before Kras V12 Exon. Note that the
allele LSL Kras V12 (before crossing with Cre) is a nul... 阅读全帖 |
|
v********a
发帖数: 646 | 18 面对这个1979年的单身女郎，从中专毕业，到参加成人自考拿到同等学历，然后一路逆
袭，最后傲然在苏州大学就职。
只有两个字：佩服
http://hlxy.suda.edu.cn/jiaoxuekeyan/yanjiushengdaoshiminglu/20
王丽，女，教授，硕士研究生导师
研究方向
慢性病运动康复：重症病者包括心脑血管疾病、骨关节系统疾病和终末期肾病等患者的
运动康复。
体能与疾病：体能水平与疾病发生和预后之间的关系；
社区康复：糖尿病、骨质疏松等的社区康复护理干预。
联系方式
电话：0512-65221499 (办公室); 138-1486-1702 (手机)
邮a class="__cf_email__" href="/cdn-cgi/l/email-protection" data-cfemail="3dd99e875154104a5c535a100c7d4e48595c13585948135e53">[email protected]/* */; [email protected]/* */
地址：苏州市十梓街1号苏州大学护理学院本部20... 阅读全帖 |
|
s***h
发帖数: 26 | 19 实在不好意思打扰了，我最近在做一个research遇到了以下几个问题，希望能够向版上
的前辈请教。虽然查过了版上的一些类似的帖子也尝试了一下，但还是决定问问：
1. 我的原始数据missing rate相当严重（总rate 50%，每个variable的 missing rate
大概在1%-20%左右）。我使用了R里面的MICE去fill进去这些missing value，但是它的
默认setting是5个sub imputation datasets，我想问问看有什么办法能够把它们合成
一个dataset？我读过了MICE的使用paper，看起来他们只能支持输出全五个datasets或
者直接在MICE的情况下run regression。我想问问看有没有使用过MICE的人有没有什么
好的方法？
2. 我的dataset原始variable数量很多（80+），其中90%是categorical变量，在R里面
有没有快速看变量之间correlation的方法（cor function应该是不适合看categorical
之间的关系的）
3. 如果我使用一些比较raw的方法删掉了一批变... 阅读全帖 |
|
s***h
发帖数: 26 | 20 实在不好意思打扰了，我最近在做一个research遇到了以下几个问题，希望能够向版上
的前辈请教。虽然查过了版上的一些类似的帖子也尝试了一下，但还是决定问问：
1. 我的原始数据missing rate相当严重（总rate 50%，每个variable的 missing rate
大概在1%-20%左右）。我使用了R里面的MICE去fill进去这些missing value，但是它的
默认setting是5个sub imputation datasets，我想问问看有什么办法能够把它们合成
一个dataset？我读过了MICE的使用paper，看起来他们只能支持输出全五个datasets或
者直接在MICE的情况下run regression。我想问问看有没有使用过MICE的人有没有什么
好的方法？
2. 我的dataset原始variable数量很多（80+），其中90%是categorical变量，在R里面
有没有快速看变量之间correlation的方法（cor function应该是不适合看categorical
之间的关系的）
3. 如果我使用一些比较raw的方法删掉了一批变... 阅读全帖 |
|
f**d
发帖数: 768 | 21 最新一期神经科学期刊
The Journal of Neuroscience DOI: 10.1523/?JNEUROSCI.0347-11.2011
译文转自 生物谷
Toronto大学的研究人员首次确定了与帕金森氏症和其他神经退行性疾病密切相关
的严重睡眠障碍的一个潜在病因。
该研究的主要作者，John Peever博士说：“我们的研究是第一次建立一个与人类
的REM睡眠行为障碍（RBD）的相关联的可能性，这很重要，因为60%至80%的诊断为
RBD的人随后进展为帕金森氏症或其他神经退行性疾病。”该研究发表在《The
Journal of Neuroscience》上。
快速动眼睡眠行为障碍（RBD）最常见的特征是在做梦睡眠（也称之为快速动眼睡
眠）中发生剧烈的运动。患有RBD的人不能体验正常的肌肉松弛，而这种肌肉松弛
可防止他们做梦，他们还经常由于快速的、强有力的运动伤害到自己或伤害到与他
们同床的配偶。在某些情况下，病人需要被固定在床上，以防止严重伤害他们自己
或他们同床的配偶。
Peever的团队重点研究了RBD的遗传的原因，因为这种疾病的根本原因是未知的。
有证据表明，减少... 阅读全帖 |
|
c**i
发帖数: 6973 | 22 Michael Wines, A U.S.-China Odyssey: Building a Better Mouse Map. New York
Times, Jan 29, 2011.
http://www.nytimes.com/2011/01/29/world/asia
/29china.html?_r=1&scp=1&sq=fudan&st=cse
Note:
(a) Tian Xu, PhD, Department of Genetics, School of Medicine, Yale
Universoty, undated.
http://medicine.yale.edu
/genetics/people/tian_xu.profile
Quote:
"Professor of Genetics; Vice Chairman of Genetics; Investigator, Howard
Hughes Medical Institute; Director, Yale Center for Functional Genomics"
"Education[:]... 阅读全帖 |
|
C********g
发帖数: 9656 | 23 余华
原文：The Spirit of May 35th （载《纽约时报》—中国来信， 2011年6月23日）
译者：爻义
你可能认为5月35日是个虚拟的日子，但在中国，它是真实存在的。它指的实际上是6月
4日，1989年发生“天安门事件“的日子，这个词在互联网上被禁掉了，人们于是使用
“5月35日”来逃避审查和纪念那天发生的事。
今年早些时候我访问台湾的时候，我的书《十个词汇里的中国》在那儿刚刚出版。我被
问到，“为什么这本书不能在大陆出版，而你的小说《兄弟》却可以？”
这就是虚构与非虚构的差别：尽管两本书都是关于当代中国的，《兄弟》触及的是隐晦
的事因而可以成为漏网之鱼，而《十个词汇里的中国》过于直白，逃不过审查。
“《兄弟》是5月35日”，我解释道，“而《十个词汇里的中国》更像6月4日。”
想要表达观点的话，5月35日式的词汇成了今天的例行规则。根据最新的数字，中国有
四亿五千七百万网民，三亿三百万中国人可以用手机上网。在网上控制这些用户不越距
是巨大的工作，政府最有效的控制机制是把某些词汇设定为不可接受，直接禁止它们在
网上使用。
于是那些热衷于表达他们自己观点的人发现他们... 阅读全帖 |
|
t*****g
发帖数: 7455 | 24 下午11:24（8 分钟前）中国人就像老鼠...从 译言-每日精品译文推荐 作者：
JACKIEXIA译者 JACKIEXIA
Chinese people are just like mice…
中国人就像老鼠...
A week or so ago I stumbled upon a Chinese language version of Animal Farm
in a local bookshop. I was slightly surprised to see it, but the back cover
described it as being about 1950’s England, so perhaps the censors signed
off on it as a criticism of the west. It was only 9rmb, so I bought it as a
gift for one of my co-workers to see how she would react.
大概一周前，我无意中在本地书店发现了一本中文版的《动物农场》，... 阅读全帖 |
|
l********k
发帖数: 14844 | 25 Secondary evolution of swimming
While tetrapods lost many of their natural adaptations to swimming when they
evolved onto the land, many have re-evolved the ability to swim or have
indeed returned to a completely aquatic lifestyle.
Primarily or exclusively aquatic animals have re-evolved from terrestrial
tetrapods multiple times: examples include amphibians such as newts,
reptiles such as crocodiles, sea turtles, ichthyosaurs, plesiosaurs and
mosasaurs, marine mammals such as whales, seals and o... 阅读全帖 |
|
h*******r
发帖数: 847 | 26 http://www.ncbi.nlm.nih.gov/m/pubmed/23284890/
CDA-2, a urinary preparation, inhibits lung cancer development through the
suppression of NF-kappaB activation in myeloid cell.
Wang X, et al. PLoS One. 2012.
Show full citation
Abstract
CDA-2 (cell differentiation agent 2), a urinary preparation, has potent anti
- proliferative and pro-apoptotic properties in cancer cells. However, the
mechanisms of tumor inhibitory action of CDA-2 are far from clear, and
especially there was no report on lung canc... 阅读全帖 |
|
发帖数: 1 | 27 【Filariasis
From Wikipedia, the free encyclopedia
Filariasis
Life cycle of Wuchereria bancrofti, a parasite that causes filariasis
Classification and external resources
Specialty Infectious disease
ICD-10 B74
ICD-9-CM 125.0-125.9
Patient UK Filariasis
MeSH D005368
[edit on Wikidata]
Filariasis is a parasitic disease caused by an infection with roundworms of
the Filarioidea type.[1] These are spread by blood-feeding black flies and
mosquitoes. This disease belongs to the group of d... 阅读全帖 |
|
发帖数: 1 | 28 12月27日 为什么我要替中国辩护
我要替中国辩护，并不是因为我是一个中国人，而是因为我知道中国就和这世界上绝大
数的国家一样，虽然有很多丑陋的现象，但是他们是受害者。就
象这个犯罪集团里很多的人一样，他们来自各种种族，他们可能充当了工具，但他们不
是制造这一切，谋划这一切的人。虽然经常会暴露中国产品出现问题。但要知道中国是
世界工厂，他们只是打工者，他们只是按照各种雇主提供的配方来生产，他们并不知道
他们会产生怎样的后果。或者这些工人知道后果，但他们只是奴隶，他们又如何去改变
这一切？ 所以，当我的调查不断往前推进的时候，不可避免地会涉及各国的企业，但
这并不表明是针对这个国家或这个国家的人民，而是针对一种社会现实和丑陋现象。就
拿菲律宾来说，菲律宾是一个犯罪猖獗的国家，有很多犯罪分子，但是菲律宾人民却是
这个集团的受害者，他们／她们被绑架，沦为了牺牲品，人体实验对象。一个日本人，
强奸上千名菲律宾女孩，却没有受到惩罚。以前我也提到过，有20个国家的名单，这20
个国家的人民其实都是受害者。现在他们把矛头对准中国，或许仅仅是因为我揭示了他
们图害世界人民的内幕，而我是一个中国人的缘... 阅读全帖 |
|
发帖数: 1 | 29 12月27日 为什么我要替中国辩护
我要替中国辩护，并不是因为我是一个中国人，而是因为我知道中国就和这世界上绝大
数的国家一样，虽然有很多丑陋的现象，但是他们是受害者。就
象这个犯罪集团里很多的人一样，他们来自各种种族，他们可能充当了工具，但他们不
是制造这一切，谋划这一切的人。虽然经常会暴露中国产品出现问题。但要知道中国是
世界工厂，他们只是打工者，他们只是按照各种雇主提供的配方来生产，他们并不知道
他们会产生怎样的后果。或者这些工人知道后果，但他们只是奴隶，他们又如何去改变
这一切？ 所以，当我的调查不断往前推进的时候，不可避免地会涉及各国的企业，但
这并不表明是针对这个国家或这个国家的人民，而是针对一种社会现实和丑陋现象。就
拿菲律宾来说，菲律宾是一个犯罪猖獗的国家，有很多犯罪分子，但是菲律宾人民却是
这个集团的受害者，他们／她们被绑架，沦为了牺牲品，人体实验对象。一个日本人，
强奸上千名菲律宾女孩，却没有受到惩罚。以前我也提到过，有20个国家的名单，这20
个国家的人民其实都是受害者。现在他们把矛头对准中国，或许仅仅是因为我揭示了他
们图害世界人民的内幕，而我是一个中国人的缘... 阅读全帖 |
|
发帖数: 1 | 30 12月28日 仔细阅读以下文章
或许这些文章可以告诉你们孩子被伤害病毒的答案。
Astellas Pharma 应该和这些人体实验有莫大的关系！
Founded 2005; 11 years ago
Headquarters 2-5-1, Nihonbashi-Honcho, Chūō-ku, Tokyo 103-8411, Japan
Key people Yoshihiko Katakana
(President and CEO)
Filariasis
From Wikipedia, the free encyclopedia
Filariasis
Life cycle of Wuchereria bancrofti, a parasite that causes filariasis
Classification and external resources
Specialty Infectious disease
ICD-10 B74
ICD-9-CM 125.0-125.9
Patient UK Filariasis
MeSH ... 阅读全帖 |
|
W*****B
发帖数: 4796 | 31 President Trump's Staff Complain of Cockroach, Mice and Ant Infestations
in the White House
Someone also requested a new toilet seat for the Oval Office
Abigail Abrams
The White House may be elaborately decorated for the holidays this time of
year, but work orders reveal the presidential mansion is also infested with
mice, cockroaches and ants.
The vermin came to light when NBC News4 Washington obtained hundreds of work
requests stretching back two years. Maintenance staff members at the White
H... 阅读全帖 |
|
s******n
发帖数: 518 | 32 【 以下文字转载自 History 讨论区 】
发信人: shaodian (有熊), 信区: History
标 题: 美国生物实验室泄露
发信站: BBS 未名空间站 (Sun Mar 22 15:25:05 2020, 美东)
Google翻译一次只能3900字符。
https://www.usatoday.com/story/news/2015/05/28/biolabs-pathogens-location-
incidents/26587505/
Investigation reveals hundreds of accidents, safety violations and near
misses put people at risk
Alison Young and Nick Penzenstadler, USA TODAY
Vials of bioterror bacteria have gone missing. Lab mice infected with deadly
viruses have escaped, and wild rodents have b... 阅读全帖 |
|
C********g
发帖数: 9656 | 33 【 以下文字转载自 ChinaNews 讨论区 】
发信人: Communipig (共产猪), 信区: ChinaNews
标 题: 5月35日的精神
发信站: BBS 未名空间站 (Sat Jul 16 20:26:54 2011, 美东)
余华
原文：The Spirit of May 35th （载《纽约时报》—中国来信， 2011年6月23日）
译者：爻义
你可能认为5月35日是个虚拟的日子，但在中国，它是真实存在的。它指的实际上是6月
4日，1989年发生“天安门事件“的日子，这个词在互联网上被禁掉了，人们于是使用
“5月35日”来逃避审查和纪念那天发生的事。
今年早些时候我访问台湾的时候，我的书《十个词汇里的中国》在那儿刚刚出版。我被
问到，“为什么这本书不能在大陆出版，而你的小说《兄弟》却可以？”
这就是虚构与非虚构的差别：尽管两本书都是关于当代中国的，《兄弟》触及的是隐晦
的事因而可以成为漏网之鱼，而《十个词汇里的中国》过于直白，逃不过审查。
“《兄弟》是5月35日”，我解释道，“而《十个词汇里的中国》更像6月4日。”
想要表达观点的话，5月35日式的词汇成了今... 阅读全帖 |
|
W*****B
发帖数: 4796 | 34 【 以下文字转载自 Military 讨论区 】
发信人: WCNMLGB (CCC), 信区: Military
标 题: 白宫蟑螂老鼠蚂蚁泛滥成灾
发信站: BBS 未名空间站 (Thu Nov 30 19:07:00 2017, 美东)
President Trump's Staff Complain of Cockroach, Mice and Ant Infestations
in the White House
Someone also requested a new toilet seat for the Oval Office
Abigail Abrams
The White House may be elaborately decorated for the holidays this time of
year, but work orders reveal the presidential mansion is also infested with
mice, cockroaches and ants.
The vermin came to light when ... 阅读全帖 |
|
w*********s
发帖数: 2136 | 35 【 以下文字转载自 Medicine 讨论区 】
发信人: whiteclouds (/ 参考消息 /), 信区: Medicine
标 题: 泰诺可杀蛇
发信站: BBS 未名空间站 (Sat Oct 2 16:51:47 2010, 美东)
Navy Bombs Guam With Dead Frozen Mice
October 01, 2010, FoxNews.com
In a ploy to rid Guam of its population of invasive brown tree snakes, the U
.S. Department of Agriculture is bombing the island with drugged frozen mice
, military news outlet Stars and Stripes reported.
Using Naval Base Guam as a starting point, scientists drop mice packed with
acetaminophen from helicop |
|
m*********g
发帖数: 646 | 36 number the bottles, and group the mice by 1023 ways. For example, for bottle
#5 let m3 and m1 test it; for bottle # 8, let m4 test it; for bottle # 11,
let m4, m2,m1 test it;
then check which combination of mice died together. Remember I mentioned
this method works when ONLY ONE bottle is poisoned (otherwise we need to
modify this question, actually, if you get the first one correctly, it is
highly possible the interviewer will ask you what if 2 bottle is poisoned) ?
Based on this condition, you... 阅读全帖 |
|
s********g
发帖数: 126 | 37 第五题给个思路》？？
4 bits are equivalent to 4 mice; each bottle has a index number 1,2,..13,
and each index can be expressed as binary (for example, 1 is 0001, 10 is
1010); give one drop to the corresponding mouse if the corresponding bit
value is 1 (for example, 10 - 1010, give 2nd and 4th mice some drink); so if
2nd and 4th mice die, it means 10th bottle is poisonous. |
|
e******e
发帖数: 57 | 38 我们是一家大型制药厂，现在有 an in vivo contract job open，目前是一年合同，
可能会延长合同. 要求工作时间比较灵活, 能在晚上８-１０ 和周末给小鼠给药。这
个工作对未来职业发展很有好处。可以把 CV 和联系方式发给我.
可以站内联系我
In Vivo Research Associate
Job description
We are seeking a highly motivated contract Research Associate with strong
interpersonal communication skills to conduct in vivo studies in mice in our
In Vivo Pharmacology group in San Diego.
Requirements
ALAT/ALATg, or BS degree in a life science with minimum 1-2 years of hands
on laboratory experience in small animal e... 阅读全帖 |
|
e******e
发帖数: 57 | 39 In Vivo Research Associate
Job description:
We are seeking a highly motivated contract Research Associate with strong
interpersonal communication skills to conduct in vivo studies in mice at our
In Vivo oncology Pharmacology group in a large pharmaceutical company in La
Jolla ( San Diego CA). This is a great opportunity to learn drug discovery
and industrial experiences.
Requirements:
ALAT/ALATg, or BS, MS degree in a life science with minimum 1-2 years of
hands on laboratory experience in small... 阅读全帖 |
|
w*********s
发帖数: 2136 | 40 Navy Bombs Guam With Dead Frozen Mice
October 01, 2010, FoxNews.com
In a ploy to rid Guam of its population of invasive brown tree snakes, the U
.S. Department of Agriculture is bombing the island with drugged frozen mice
, military news outlet Stars and Stripes reported.
Using Naval Base Guam as a starting point, scientists drop mice packed with
acetaminophen from helicopters into the jungle canopy.
The drug -- commonly found in Tylenol -- provided a regulatory advantage
because it had already |
|
w*********s
发帖数: 2136 | 41 【 以下文字转载自 Medicine 讨论区 】
发信人: whiteclouds (/ 参考消息 /), 信区: Medicine
标 题: 泰诺可杀蛇
发信站: BBS 未名空间站 (Sat Oct 2 16:51:47 2010, 美东)
Navy Bombs Guam With Dead Frozen Mice
October 01, 2010, FoxNews.com
In a ploy to rid Guam of its population of invasive brown tree snakes, the U
.S. Department of Agriculture is bombing the island with drugged frozen mice
, military news outlet Stars and Stripes reported.
Using Naval Base Guam as a starting point, scientists drop mice packed with
acetaminophen from helicop |
|
s********e
发帖数: 427 | 42 The findings, published online on Dec. 14 in Nature Medicine, could restart
work on effective killed-virus vaccines not only for RSV but other
respiratory viruses, researchers say. The new findings also debunk a popular
theory that the 1966 vaccine was ineffective because the formalin used to
inactivate the virus disrupted critical antigens, the substances that
stimulate the production of protective antibodies.
Instead, researchers said, the problem occurred when the antibodies created
by the va... 阅读全帖 |
|
s********e
发帖数: 427 | 43 The findings, published online on Dec. 14 in Nature Medicine, could restart
work on effective killed-virus vaccines not only for RSV but other
respiratory viruses, researchers say. The new findings also debunk a popular
theory that the 1966 vaccine was ineffective because the formalin used to
inactivate the virus disrupted critical antigens, the substances that
stimulate the production of protective antibodies.
Instead, researchers said, the problem occurred when the antibodies created
by the va... 阅读全帖 |
|
发帖数: 1 | 44 12月27日 为什么我要替中国辩护
我要替中国辩护，并不是因为我是一个中国人，而是因为我知道中国就和这世界上绝大
数的国家一样，虽然有很多丑陋的现象，但是他们是受害者。就
象这个犯罪集团里很多的人一样，他们来自各种种族，他们可能充当了工具，但他们不
是制造这一切，谋划这一切的人。虽然经常会暴露中国产品出现问题。但要知道中国是
世界工厂，他们只是打工者，他们只是按照各种雇主提供的配方来生产，他们并不知道
他们会产生怎样的后果。或者这些工人知道后果，但他们只是奴隶，他们又如何去改变
这一切？ 所以，当我的调查不断往前推进的时候，不可避免地会涉及各国的企业，但
这并不表明是针对这个国家或这个国家的人民，而是针对一种社会现实和丑陋现象。就
拿菲律宾来说，菲律宾是一个犯罪猖獗的国家，有很多犯罪分子，但是菲律宾人民却是
这个集团的受害者，他们／她们被绑架，沦为了牺牲品，人体实验对象。一个日本人，
强奸上千名菲律宾女孩，却没有受到惩罚。以前我也提到过，有20个国家的名单，这20
个国家的人民其实都是受害者。现在他们把矛头对准中国，或许仅仅是因为我揭示了他
们图害世界人民的内幕，而我是一个中国人的缘... 阅读全帖 |
|
g*******3
发帖数: 2520 | 45 早在本版表达过自己的观点，非独立推荐人的推荐信如果写的好，也可以起很大作用。重点是他谈的都是就事实来说话，不是光说你牛啊，牛啊牛。所以这样非独立也就有power了，还有就是讲detail,这样贡献就很清晰了。我block了一些个人信息，但最大可能的保留了原文，基本到了可以被人肉的地步，但只要对后来人有用，被人肉了也在所不辞.在此也要special thank 我的老板，居然花了两个小时在办公室给我修改律师写好的推荐信。
------------------------------------------------------
Dear Sir or Madam:
This letter serves to express my strong support to Dr. Genegun, an immunologist who has made significant contributions to our understanding of immunosenescence --- the decline in immune responsiveness that occu... 阅读全帖 |
|
w*****t
发帖数: 179 | 46 您好，不知道我的背景能否审到这片文章。我曾经审过一些小杂志，希望能够对我争取
这次机会有所帮助。详细的CV和研究背景如下。非常感谢您的考虑。我的工作邮箱：
z****[email protected]
好像CV在这里粘贴很难看，不好意思。前一段时我的CV，后一段我的较详细的研究经历
。如有需要我更详细的背景情况，请跟我发信。
1
CURRICULUM VITAE
Full Name: Zhimin Wang
Address: Allegheny-Singer Research Institute, West Penn Allegheny, Health
System, South Tower, 320 East North Avenue, Pittsburgh, PA 15212-4772
Phone: 412-359-6153 (Office)
412-737-3777 (Cell)
E-mail: z****[email protected] w************[email protected]
EDUCATION
September, 2001- May, 2005 Ph.D., Molecular M... 阅读全帖 |
|
w*****t
发帖数: 179 | 47 hello, thank you for providing the information. Please find my CV below and
my research experience. I have been revewing for over 10 journals for 14
times. My majour of PH.D is microbiology from Wuhan university. I have
published several papers concering virology and bacterial infection. So far
my work also foucse on salivary gland biofilm formation under LL37 and K4s4
treatment. If you need further information, please let me know. My email
address: z****[email protected]
Thank you for your time and c... 阅读全帖 |
|
y*****o
发帖数: 2364 | 48 Big bless for myself. too much stress now. I have a fight with the present
boss. I do every thing in the lab, from booking to cleaning. Mice raring,
recording and tissue sectioning.In the morning lab meeting (every week), he
blame me whithout new data in this week, WOW. Only me doing work in this lab
, another postdoc is boss wife who counts on me doing every her experiments.
Plus, by checking 13 mice genotyping from her previous record, 4 mice strain
are wrong.My god, what kind of results are r... 阅读全帖 |
|
N********n
发帖数: 13236 | 49 你在非洲工作，就不买礼物给这里的pretty mice，二mice，三mice啦？ |
|
发帖数: 1 | 50 NIH-supported Postdoctoral Fellow Positions in Leukocyte Biology and
Immunology at the University of Connecticut School of Medicine (UConn Health)
Our laboratory is looking for motivated postdoctoral fellows to study
integrin activation and leukocyte trafficking in inflammatory diseases using
advanced microscopy, such as super-resolution microscopy, high-resolution
live-cell imaging, and intravital microscopy.
We work on primary human leukocytes, leukocyte-like cell lines, and gene-
edited mice ... 阅读全帖 |
|
