R*******t
发帖数: 367 | 1 太赞了！能说说为什么poorly differentiated NSCLC让你觉得活检样品不足吗？还有
什么样的病例结果让你觉得需要重新活检的，除了病理说,inadequate specimen以外？
谢谢。
metastatic
of
efficacy |
|
d******g
发帖数: 2 | 2 左乳全切，前哨淋巴只切了一个，有isolated tumor cell, 但医生说按现在的标准算
Negative，不需radiation。
biospy时左乳发现的两个tumor：
乳头处的tumor HER2是negative (IHC score 2+，FISH negative) ；
12点的tumor HER2是positive (IHC score 3+)。
手术病理显示有两块 specimen, 因为有re-excision。
但是只发现一个 tumor(乳头处)，1.5cm, HER2结果和biopsy时乳头处的tumor一样，
IHC score 2+, FISH negative，另一个(12点)不仅tumor没找到，biopsy时放到那的
clip也找不到。后来作过X-RAY， US， MRI，没有发现体内有什么残留。
本来医生说chemo会采用 TCH*6 with HERCEPTIN for 1 year based on the fact that
ONCOTYPE SCORE for the tumor at nipple is 20 (intermedi... 阅读全帖 |
|
g******1
发帖数: 45 | 3 I am I did not read carefully. They did FISH on the biopsy specimen taken
from 12:00. It was negative. You most likely don't need Herceptin. I am
sorry about this. |
|
a*********1
发帖数: 872 | 4 也来写下我的病理internship.我们这里6月份只有institutional orientation,所里真
正进program是从7月2号开始。前两个月都算orientation,grossing有chief手把手教的
，一天gross大标本，第二天signout。第一个星期不知道怎么搞的，specimen不多，中
间独立日还放了一天，开会，看autopsy,还没什么感觉就过去了。 第二周开始标本多
了，chief稍微一放手，我就犯了错误。一次是dictate size，结果没dictate进去,
attending问我也不记不清了，最后用slide上拼着估计了一下，下次要把dictate的号
码记下来这样还可以回过去查，另外一次submit lymph nodes,slide key 写成A1
lymph nodes-4,attending搞不清是4个完整的，还是一个切成4块，所以正确的说法是
four lymph nodes-4。还有thyroid tumor,4cm是staging的cutoff值，得注意。
我们这级里面其他都是刚毕业的美国人，人好相处，但是生活太不一样。... 阅读全帖 |
|
h******u
发帖数: 602 | 5 In GI system, stage is usually determined by maximal depth of invasion, not
tumor size, so 4 cm or 6 cm will not make a big difference. However in
other organ systems, like breast, lung, size determins stage. 2.9 cm and 3
cm in a lung tumor will change its stage. Check CAP Cancer protocol for
detail.
Every time you gross a specimen, always keep in mind: orientation, ink,
measurement, weight.....
是 |
|
C*****D
发帖数: 1299 | 6 Was the specimen sent to the commercial lab or hospital for pathology? |
|
b******a
发帖数: 704 | 7 Common Causes of Pneumonia
In a young patient without coexisting illnesses, there are many potential
infectious causes of pneumonia.1 The patient's history gives us several
clues that help in reducing the list of possible pathogens. This patient
underwent bronchoscopy and bronchoalveolar lavage. Negative bacterial
cultures argue against common, easy-to-culture bacterial pathogens.
Furthermore, the patient did not have a response to multiple, broad-spectrum
antibacterial therapy including erythro... 阅读全帖 |
|
M***D
发帖数: 249 | 8 I have 10 years of research experience in cell culture study (6 years for my
PhD and 4 years as a post-doctoral research fellow), I hope I can help you
to understand Dr. Chen's study better:
(1) Cell cultures
-Cultured normal cells have limited growth in a petri-dish due to lateral
inhibition, while cultured cancer cells grow much faster comparing to
cultured normal cells. Therefore, you must "pass" the cultured cancer cells
from one petri-dish to 2 petri-dishes more frequently in order to keep ... 阅读全帖 |
|
i*****r
发帖数: 265 | 9 【 以下文字转载自 MedicalCareer 讨论区 】
发信人: integer (integer), 信区: MedicalCareer
标 题: 关于乳腺癌，大牛看看
发信站: BBS 未名空间站 (Wed Feb 4 02:49:02 2015, 美东)
帮个朋友问的，57岁，下面是病理报告：
Examination Findings
Specimen of right breast mass 4X2X3CM was sent for inspection. A grey nodule
with size of 2.5X2CM was found in the section. Endoscope finding: The tumor
cells were in nest shape and glandular tube. The cells arranged solidly and
grew invasively. Nuclear fission was easy to see, and nuclear atypia was
obvious. No cancer met... 阅读全帖 |
|
|
f**d
发帖数: 768 | 11 这是一本计算神经科学的优秀著作，全文拷贝这里（图和公式缺），有兴趣的同学可以
阅读
如需要，我可以分享PDF文件（－－仅供个人学习，无商业用途）
From Computer to Brain
William W. Lytton
From Computer to Brain
Foundations of Computational Neuroscience
Springer
William W. Lytton, M.D.
Associate Professor, State University of New York, Downstato, Brooklyn, NY
Visiting Associate Professor, University of Wisconsin, Madison
Visiting Associate Professor, Polytechnic University, Brooklyn, NY
Staff Neurologist., Kings County Hospital, Brooklyn, NY
In From Computer to Brain: ... 阅读全帖 |
|
I***i
发帖数: 14557 | 12 http://www.cbsnews.com/8301-202_162-57492524/report-mutated-but
August 13, 2012 10:52 PM
Report: Mutated butterflies found near Fukushima
(CBS News) A group of scientists in Japan made a surprising discovery by
finding large numbers of specimens of pale grass blue butterflies that had
mutated.
In a report in the Scientific Reports journal, the scientists said their
research concluded that "that artificial radionuclides from the Fukushima
Nuclear Power Plant caused physiological and genetic damag... 阅读全帖 |
|
i*****s
发帖数: 15215 | 13 这是最近抓到的一条超大Eastern Diamondback.
A 7.3 feet (2.2 m) specimen was caught and killed outside a neighborhood in
St. Augustine, Florida in September 2009. |
|
I***i
发帖数: 14557 | 14 Officially, giant eyeball was from smallish swordfish
http://www.myfoxtampabay.com/story/19866069/2012/10/19/official
ST. PETERSBURG (FOX 13) - The giant eyeball that made headlines after
washing ashore has a new home in St. Pete. It's now preserved among the tens
of thousands of specimens at the Fish and Wildlife Research Institute.
The eyeball washed ashore on Pompano Beach on the east coast last week. It
was brought to FWC's research offices in St. Pete for genetic testing and
preservation.
T... 阅读全帖 |
|
i*****s
发帖数: 15215 | 15 这组照片是Boston Globe的照片专题The Big Pictures里的一个主题，照片都很精彩，
本帖后面有链接。
Animals and their people
We keep them as pets, although which species maintains the upper paw in that
relationship is sometimes in doubt. We drive them to the brink of
extinction, and then make desperate attempts to bring them back. We tend
them as livestock, display them in zoos, and research them in labs and in
the wild. Our lives are intertwined with those of animals, and better for
it. Gathered here are images of that furry in... 阅读全帖 |
|
|
I***i
发帖数: 14557 | 17 （才知道，龙虾竟然是很长寿的动物。）
http://www.huffingtonpost.com/2012/11/30/lobster-age_n_2215990.
Lobster Age Shown By Counting Its Rings Like A Tree, Study Reveals
PORTLAND, Maine -- For the first time, scientists have figured out how to
determine the age of a lobster – by counting its rings, like a tree.
Nobody knows how old lobsters can live to be; some people estimate they live
to more than 100.
But knowing – rather than simply guessing – their age and that of other
shellfish could help scientists better u... 阅读全帖 |
|
S****r
发帖数: 260 | 18 http://www.msnbc.msn.com/id/50071912/ns/technology_and_science-
All hail the queen: Space-flown spider Nefertiti dies in museum
She survived space station trip, but dies days after going on public display
at Smithsonian
The Smithsonian's exhibition of the first jumping spider to survive the trip
to space has turned out to be short lived: The arachnid astronaut died just
days after going on display.
"It is with sadness that we announce the death of Nefertiti, the 'spidernaut
,'" the staff at the ... 阅读全帖 |
|
S****r
发帖数: 260 | 19 The 'spidernaut,' NASA's new insect zoo star, dies
http://www.latimes.com/news/nation/nationnow/la-na-nn-spidernau
WASHINGTON — The “spidernaut” has died.
Just days after becoming a star attraction at the National Museum of Natural
History’s Insect Zoo, the spider that spent 100 days in space was found
dead Monday.
“The unexpected loss of this special animal who inspired so many
imaginations will be felt throughout the museum community,” Kelly Carnes, a
museum spokeswoman, said.
The spider, name... 阅读全帖 |
|
I***i
发帖数: 14557 | 20 http://blogs.smithsonianmag.com/smartnews/2012/12/spider-builds
Spider Builds Fake Spider Decoy
Deep in the Peruvian Amazon, a spider is at work building an elaborate, fake
decoy of itself. In its web, it busily goes to working crafting its doppelg
änger out of leaves, debris and dead prey insects, including multiple
spidery legs, a head and abdomen, Wired reports.
The new spider, thought to be a member of the genus Cyclosa, might build
these decoys as part of a defense mechanism to confuse... 阅读全帖 |
|
I***i
发帖数: 14557 | 21 Four-Winged Bird Discovered by Chinese Paleontologists
http://frenchtribune.com/teneur/1316758-four-winged-bird-discov
A study published in the journal Science has shed light on 11 four-winged
fossil specimens that lived about 130 million years ago.
It says there is strong evidence, after recently excavated primitive bird
species, that the primitive species were available with four wings.
According to the Chinese paleontologists, modern-day birds have evolved from
the pre-historic birds.
After s... 阅读全帖 |
|
|
z*******n
发帖数: 1034 | 23 By Lee Mathews Jun. 27, 2014 7:32 am
5000-year-old-poop
A team of archaeologists in Spain have really stepped in it this time, but
that’s a good thing. They’ve uncovered what is believed to be the oldest
fossilized human poo. Five whole piles of it.
The Neanderthal coprolites (a generic but shapely specimen is pictured above
) are around 50,000 years old, which lines up nicely with the age of the dig
site at El Salt in southeastern Spain. It’s known to have been occupied by
Neanderthals for t... 阅读全帖 |
|
n****o
发帖数: 13 | 24 PA working conditions and salary
PA大部分任职于hospitals，这一部分也是薪水相对最高最稳定福利也最好的，朝九晚
五，因为overtime的情况一般都有pathologist residents处理。还有一部分在
reference labs和各种private labs，这些lab因为处理的specimen数量庞大，所以可
能需要night shift，平均薪水比医院略低。还有很少的一部分在forensic和政府部门。
统计来说，New grad PA的薪水大约从75k-90k不等，就我知道的case来说，几个前两届
的毕业生大约都拿到80-85k的offer。Experienced PA能拿到6位数。PA的薪水大约是加
州最高，这些年一直PA工作机会很多，一些有PA program的states（供大于求）和相对
比较偏远的state（ex. Maine）薪水较低。
Accredited programs
目前NAACLS认证的program一共12个，我记得都是两年制master program （maybe not
accurate），包... 阅读全帖 |
|
n****o
发帖数: 13 | 25 How to apply?
PA program一般都比较competitive，每个program每年招收的人数很少，小的program
大约5-8人，中等的12-16人，最大的program应该是quinnipiac university每年招24-
26人。我所知道的录取比例大约1/9-1/10。
1.Prerequisite courses
每个program的要求都不太一样，不过大概包括chemistry，organic chemistry，
biochemistry，microbiology，biology，anatomy，physiology这些基本的课程。如果
上过pathology，histology，immunology，cell biology，genetics这些课程，那更是
巨大的plus。
这个program的外国人很少，其中一个原因是大部分program要求prereqs必须on us or
canada based transcript，也就是说即使已经在美国博士毕业，如果这些课是当年在
其他国家上本科的时候修的，也不被承认。就是因为这个要求让我多耗费了... 阅读全帖 |
|
h******2
发帖数: 1498 | 26 Welcome to the wonderful world of triathlon, where you can see many
beautiful female specimens of the human species. |
|
r*****s
发帖数: 59 | 27 老公的精液检查报告出来了，医生什么都没说。
我看了一下，Progression分值只有1+到2 。
网上查了一下，看到以下的标准：
Motility and forward progression: normally >50% of sperm in the specimen are
motile. Forward progression describes how fast the motile sperm
are moving (normal 2+ in the scale from 0 to 4)
0 No movement
1 Movement, none forward
1+ Occasional movement of a few sperm
2 Slow, undirected
2+ Slow , directly forward movement
3- Fast, but undirected movement
3 Fast, directed forward movement
3+ Very fast forward movement
4 Extremely fast |
|
t*******e
发帖数: 912 | 28 Pat pat.. Just finish the cycle and then think about what could be the next
step. Yes life sucks but life goes on.
My hubby gave another specimen to clinic and got 0 sperm count. Not even 1
sperm. This is the 3rd time he got 0 count sperm. We don't know what is
going on. |
|
w*******y
发帖数: 60932 | 29 Kids.woot Has:
HEXBUG nano Bridge Battle Habitat Set $14.99 + $5 shipping (19.99 total)Link:
http://kids.woot.com/
HEXBUG nano Bridge Battle Habitat Set - Model# 477-1631
Components:
- (1) easy connect Bridge Battle Piece
- (6) easy connect curved pieces
- (2) easy connect straight pieces
- (4) easy connect hex cell pieces
- (16) easy connect standoff pieces
- (2) HEXBUG nano specimens
The Price on amazon is 28.88 with free shipping with Prime.
|
|
T*********s
发帖数: 17839 | 30 it seems H1N1 not over yet
from CDC
This is the final report of the 2009-2010 season.
The first weekly influenza surveillance report of the 2010-2011 season (week
40, week ending October 9, 2010) will be published on October 15, 2010.
Synopsis:
During week 20 ( May 16-22, 2010), influenza activity decreased in the U.S.
* Two (0.2%) specimens tested by U.S. World Health Organization (WHO)
and National Respiratory and Enteric Virus Surveillance System (NREVSS)
collaborating laboratories and re |
|
e*n
发帖数: 1511 | 31 Not sure why my post yesterday didn't come through; brief summary this
time. Helicos gave a phenomenal presentation at the American
Association for Cancer Research annual meeting yesterday. Any of the
~1,000 audience members who witnessed the session should chime in to
validate this post. To me, they presented themselves as the clearly
superior sequencing technology in front of a very important audience
that includes the medical and academic institutions investing heavily
in sequencing technol... 阅读全帖 |
|
b****n
发帖数: 865 | 32 Were you commenting on my opinion or my friend's review?
Are you female? As a male specimen of the homo sapien,
I am not sure I'm qualified to judge feminism. Though
I try to make objective observations.
Take a course and you became a feminist? I always think you need
more life experience to reach that stage?
Agree you heer. That's where I disouted with my friend.
But the movie is still enjoyable. The tongue-in-cheek
irony and dark humour is so obviously there. Any thing with
that sense of humo |
|
y*****n
发帖数: 5016 | 33 有朋友从国内发来以下的短文请朕帮忙翻译，朕竟然看不懂，汗！有没有人能翻译出来
的？
Specimen 42.13a
Letter of Participation Guarantee
To: Public Power Corporation S.A
30, Chalkokondyli Street
Athens, 104-32 Greece
Date:
We wish to inform you that we irrevocably and unreservedly guarantee in
favor of your bidder Nanyang Cable Group having its seat or domiciled in No
1 Lane second, zhujin industry zone, Shantou China waiving expressly and
unreservedly the exception of claiming the benefit of option and our right
objections of all k... 阅读全帖 |
|
E********t
发帖数: 2447 | 34 Round 1
16 (16)
Dallas
Zack MartinG School:Notre Dame NFP Rank:22
It's not the pick the fans wanted, but Martin will be a terrific addition
for the Cowboys — at any of the offensive line positions. He's a proven,
smart lineman who will keep Tony Romo (sorry, not Johnny Manziel) and his
twice-operated-on back upright.
Round 2
14 (46)
Pittsburgh
Stephon TuittDT School:Notre Dame NFP Rank:33
The Steelers make a classic pick in Tuitt, a long-armed hulk who played much
better in 2012, when he wasn't ... 阅读全帖 |
|
e***e
发帖数: 3872 | 35 [cont.]
Joseph: What varied and difficult requirements this definition of yours
has!
Aloys: I do not deny at all, Joseph, that it is not possible for novices,
for whom it is not easy to recognize the commonplace at first, to achieve
this in all respects; nor can they reach this stage unless they are first
able to become familiar with the common things. For you, Joseph, who have
given such splendid specimens of your progress up to now, it may perhaps be
possible to arrive at this stage; I sha |
|
