发帖数: 1 | 1 【 以下文字转载自 Joke 讨论区 】
发信人: pokerfuker (mike), 信区: Joke
标 题: 我筛出来的一个compound
发信站: BBS 未名空间站 (Fri Mar 3 12:11:13 2017, 美东)
01年的时候,我从平顶山卫校毕业,用MD的头衔,在美国50名左右的医学院找到了
postdoc的位置。之后的两年里我专心考board,在科研上产出很低。03年的时候,我被
告知,虽然board考的非常好,但美国不承认卫校的MD学历。无奈之下我只好放弃了从
医之路。于是在科研的道路上一走10多年。
04年的时候,老板拿了NIA的一个大PO1 grant。几个中心一起做端粒的研究。当时这个
概念炒得很火。我们lab主要负责药物筛选。化合物库是默克的。默克当时用这个库筛
出了几个一型糖尿病的小分子,做得很成功,但用完后,这个库就废了。大概有13万多
个compound吧。我的任务就是从这13万多个compound里面筛选出有用的,用于抗衰老的
研究。
我先做酵母模型,做了1年多吧,筛出了几个化合物,这些化合物可以显著影响酵母衰
老模型。但并不作用于端粒... 阅读全帖 |
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l*******1 发帖数: 16217 | 2 【 以下文字转载自 Joke 讨论区 】
发信人: pokerfuker (mike), 信区: Joke
标 题: 我筛出来的一个compound
发信站: BBS 未名空间站 (Fri Mar 3 12:11:13 2017, 美东)
01年的时候,我从平顶山卫校毕业,用MD的头衔,在美国50名左右的医学院找到了
postdoc的位置。之后的两年里我专心考board,在科研上产出很低。03年的时候,我被
告知,虽然board考的非常好,但美国不承认卫校的MD学历。无奈之下我只好放弃了从
医之路。于是在科研的道路上一走10多年。
04年的时候,老板拿了NIA的一个大PO1 grant。几个中心一起做端粒的研究。当时这个
概念炒得很火。我们lab主要负责药物筛选。化合物库是默克的。默克当时用这个库筛
出了几个一型糖尿病的小分子,做得很成功,但用完后,这个库就废了。大概有13万多
个compound吧。我的任务就是从这13万多个compound里面筛选出有用的,用于抗衰老的
研究。
我先做酵母模型,做了1年多吧,筛出了几个化合物,这些化合物可以显著影响酵母衰
老模型。但并不作用于端粒... 阅读全帖 |
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发帖数: 1 | 3 01年的时候,我从平顶山卫校毕业,用MD的头衔,在美国50名左右的医学院找到了
postdoc的位置。之后的两年里我专心考board,在科研上产出很低。03年的时候,我被
告知,虽然board考的非常好,但美国不承认卫校的MD学历。无奈之下我只好放弃了从
医之路。于是在科研的道路上一走10多年。
04年的时候,老板拿了NIA的一个大PO1 grant。几个中心一起做端粒的研究。当时这个
概念炒得很火。我们lab主要负责药物筛选。化合物库是默克的。默克当时用这个库筛
出了几个一型糖尿病的小分子,做得很成功,但用完后,这个库就废了。大概有13万多
个compound吧。我的任务就是从这13万多个compound里面筛选出有用的,用于抗衰老的
研究。
我先做酵母模型,做了1年多吧,筛出了几个化合物,这些化合物可以显著影响酵母衰
老模型。但并不作用于端粒,因而老板并不十分高兴。我用我有限的有机化学知识,归
纳出了这几个看似截然不同的化合物的共同点,并与当时已经筛出的一些化合物做比对
,再通过生化验证,终于证明这一类带巯基苯环的化合物作用于SIRT2通路。我又从各
个公开的库里面,搜集了700多... 阅读全帖 |
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s*y 发帖数: 472 | 4 【 以下文字转载自 Business 讨论区 】
发信人: sxy (sxy), 信区: Business
标 题: 【学术探讨】问一个interest rate compounding的问题
发信站: BBS 未名空间站 (Sun May 1 23:30:30 2011, 美东)
看到investopedia上关于interest rate compounding的计算:
http://www.investopedia.com/articles/07/continuously_compound.a
我觉得前面一半完全错了,按照他那种算法,同样是年利率12%, compounding越freque
nt,反而最后实际利率变低了。
按照以前学的,如果年利率12% continuous compounding, 实际利率应该是exp(0.12)
= 1.1275%。
难道这网页上要说明的问题是同样百年实际利率6%的情况下,compounding rate的大小
?那的确是compounding越frequent,需要的rate越低。不过实在不明白不明白这样的计
算有什么意义。
各位有什... 阅读全帖 |
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w******s 发帖数: 1429 | 5 【 以下文字转载自 Living 讨论区 】
发信人: whoumass (who), 信区: Living
标 题: spacking compound 和 joint compound 有什么区别亚
发信站: BBS 未名空间站 (Wed Sep 1 16:09:07 2010, 美东)
我们要补个墙上的大洞,我家有spacking compound还是会变色的那种.要不要买joint
compound呢?
好像spacking compound不能用在会热胀冷缩的地方,所以一般用来补补钉子的洞. |
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w*******y 发帖数: 60932 | 6 Arctic Cooling MX-2 8Gram Thermal Compound $2.99 f/s
Link:
http://www.mwave.com/mwave/SKUSearch.asp?px=DS&scriteria=AA7919
Description:
ARCTIC MX-2 is the thermal compound offering high thermal conductivity and
low thermal resistance to dissipate heat efficiently from CPU / GPU to the
installed heatsink.
Features:
Excellent Performance
The ARCTIC MX-2 compound is composed of carbon micro-particles which lead to
an extremely high thermal conductivity. It guarantees that heat from the
CPU or GPU c... 阅读全帖 |
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f*****t 发帖数: 895 | 7 今天painter来房子里把墙纸撕了,painter说有一部分hallway的墙纸下面有joint
compound,很难除掉。painter说有两种解决方案:
1. 直接在joint compound上面刷primer,然后刷漆。joint compound应该不会影响油
漆的质量。他会找油漆店里的人来评估这个方案。
2. 加钱请人把joint compound一点一点的刮掉。还没说要加多少钱,听他的意思估计4
,5百块是需要的的。
请问,joint compound有那么难搞掉吗?是不是一定需要搞掉? |
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s*y 发帖数: 472 | 8 看到investopedia上关于interest rate compounding的计算:
http://www.investopedia.com/articles/07/continuously_compound.a
我觉得前面一半完全错了,按照他那种算法,同样是年利率12%, compounding越freque
nt,反而最后实际利率变低了。
按照以前学的,如果年利率12% continuous compounding, 实际利率应该是exp(0.12)
= 1.1275%。
难道这网页上要说明的问题是同样百年实际利率6%的情况下,compounding rate的大小
?那的确是compounding越frequent,需要的rate越低。不过实在不明白不明白这样的计
算有什么意义。
各位有什么看法? |
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w******s 发帖数: 1429 | 9 我们要补个墙上的大洞,我家有spacking compound还是会变色的那种.要不要买joint
compound呢?
好像spacking compound不能用在会热胀冷缩的地方,所以一般用来补补钉子的洞. |
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h********8 发帖数: 7355 | 13 Spackling compound 干后变成白色, 干的快些,价格贵不少。
Joint compound 要24hr 才干,甚至更久, 但很便宜。 |
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w*******p 发帖数: 253 | 14 【 以下文字转载自 EE 讨论区 】
发信人: windowsxp (windowsxp), 信区: EE
标 题: [Job opening] Compound Semiconductor Process Technician
发信站: BBS 未名空间站 (Thu Sep 9 15:32:49 2010, 美东)
Compound Semiconductor Process Technician
Job Description
• Perform multiple processing and verification steps routinely in a
small III-V compound semiconductor fab.
• Processing steps include: photolithography, metallization, wet
and dry etching.
• Follow processing recipes and procedures.
• Do all s |
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c****1 发帖数: 1095 | 15 HPLC检测compound,只有一个单峰,是不是说明compound很纯?从合作者那里拿来
compound,每次都说很纯。但是,有时候是黄色的,有时是白的的。人家说,这颜色不
代表纯度。
我完全不懂这次化学合成的技术问题。请教大家,HPLC单峰,可以说明纯度么?不同批
次,不同颜色,说明什么问题? |
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y**********t 发帖数: 37 | 16 Sorry can't type Chinese in this computer
1. What is the most accurate parameter (thermodynamically or kinetically) to
describe how stable of a compound to the heat?
2. The Arrhenius equation to calculate rate constant k is based on the
activation energy between the compound and its transition state species, and
the pro-exponential factor which is poorly documented. Is there any decent
estimation of activation energy and pro-exponential factor. e.g. how to
calculate the decomposition rate of ace... 阅读全帖 |
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w*******y 发帖数: 60932 | 17 Sears
Craftsman Compound Action Bypass Lopper
$24.99 - $10 Instant Savings
= $14.99 with Free Store Pickup
Compound Action Bypass Lopper
* 112" diameter cutting capacity
* Unique compound cutting action triples your cutting power
* Fully heat treated high-carbon steel bypass cutting head
* PTFE non stick coated blade for easy clean cuts
* Lightweight, strong aluminum handles with ergonomic grip
|
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w*******y 发帖数: 60932 | 18 Link:
http://www.mwave.com/mwave/SKUSearch_v3.asp?px=HP&scriteria=BA21525
Join as an "M" club member and get it for $1.99
Description:
Cooler Master htk-002-u1 Thermal Compound
Cooler Master HTK-002-U1 thermally conductive compounds are grease-like
silicone materials, heavily filled with heat conductive metal oxides. This
combination promotes high thermal conductivity, low bleed and high-
temperature stability. These compounds resist changes in consistency at
temperatures up to 177C (350F), main |
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w*******y 发帖数: 60932 | 19 Link:
http://www.sears.com/shc/s/p_1015...183719000P
Craftsman Compound Action Bypass Lopper
Reg Price: $25.99
Savings: $10.00
$15.99
Free Store Pickup or + $7.75 shippingl
Compound Action Bypass Lopper
* 1-1/2" diameter cutting capacity
* Unique compound cutting action triples your cutting power
* Fully heat treated high-carbon steel bypass cutting head
* PTFE non stick coated blade for easy clean cuts
* Lightweight, strong aluminum handles with ergonomic grip
General Warranty: Lifetime
Apparen... 阅读全帖 |
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F*V 发帖数: 3978 | 20 Cairo (CNN) -- Angry protesters attacked U.S. diplomatic compounds in Libya
and Egypt on Tuesday, citing in both instances an online film considered
offensive to Islam.
In Cairo, several men scaled the walls of the U.S. Embassy and tore down its
American flag, according to CNN producer Mohammed Fahmy, who was on the
scene.
In Libya, witnesses say members of a radical Islamist group called Ansar al-
Sharia protested near the U.S. Consulate in Benghazi, where NATO jets
established no-fly zones las... 阅读全帖 |
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W**********n 发帖数: 187 | 21 Cairo (CNN) -- Angry protesters attacked U.S. diplomatic compounds in Libya
and Egypt on Tuesday, citing in both instances an online film considered
offensive to Islam.
In Cairo, several men scaled the walls of the U.S. Embassy and tore down its
American flag, according to CNN producer Mohammed Fahmy, who was on the
scene.
In Libya, witnesses say members of a radical Islamist group called Ansar al-
Sharia protested near the U.S. Consulate in Benghazi, where NATO jets
established no-fly zones las... 阅读全帖 |
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g**1 发帖数: 10330 | 22 http://www.reuters.com/article/us-usa-russia-cyber-idUSKBN14I1TY
The United States on Thursday expelled 35 Russian diplomats and closed two
Russian compounds in New York and Maryland in response to a campaign of
harassment by Russia against American diplomats in Moscow, a senior U.S.
official said on Thursday.
The U.S. official, speaking on condition of anonymity, told Reuters the
Russian diplomats would be given 72 hours to leave the United States. Access
to the two compounds will be denied to ... 阅读全帖 |
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F*V 发帖数: 3978 | 23 Cairo (CNN) -- Angry protesters attacked U.S. diplomatic compounds in Libya
and Egypt on Tuesday, citing in both instances an online film considered
offensive to Islam.
In Cairo, several men scaled the walls of the U.S. Embassy and tore down its
American flag, according to CNN producer Mohammed Fahmy, who was on the
scene.
In Libya, witnesses say members of a radical Islamist group called Ansar al-
Sharia protested near the U.S. Consulate in Benghazi, where NATO jets
established no-fly zones las... 阅读全帖 |
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a*****y 发帖数: 1488 | 24 昨天遇到两个做私活的,帮我把车身上的一个很大的坑给搞好了。最后他喷了一些 car
paint imperfection compound, 说我过4个小时后用soap water 擦掉就好了。现在倒
是能擦掉,不过非常慢,一定要那种有点挂丝的布,一点一点慢慢擦才行,太费时间了。
请问有没有人有经验,这些compound怎么擦最快,又不伤本身的车漆。 |
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O****a 发帖数: 68 | 25 我今天倒车没注意 后视镜擦到了柱子 留下了印子 准备买meguiars 的ultimate
compound 和scratchx 试一下可不可以复原 现在的问题就是如果弄了compound或者
scrathx 然后wash 最后还需要wax吗?? 这个还是比较新的车 我看说新车不需要wax
或者应该上clearcoat吗 |
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k*********s 发帖数: 4474 | 26 如果漆掉了:
1. 洗干净再Compound 把脏东西打磨掉
2. 上touch up paint, 等干
3. 砂纸 wet sand 凸岀来的touch up paint
4. Compound + polish + liquid wax (推荐Meguiar's)
wax |
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m******g 发帖数: 3667 | 27 我看是网上算月付,是APR除以12,是compounded monthly? 那这个APR一点意义都没有
,实际利息要比APR高得多 |
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c**********e 发帖数: 2007 | 28 monthly compound. The actual annual rate is higher than the nominal rate. |
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a***e 发帖数: 27968 | 29 你是还贷,丫怎么利滚利?
你的月付比利息高,利息先付掉
再付本金,根本没利滚利的机会
你自己算算就知道了
要不你给个不compound的例子?
★ 发自iPhone App: ChineseWeb 11 |
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k****y 发帖数: 4083 | 30 墙里装10/3电线,墙上开了几个洞,转角处金属外层有破损,露出纸包着的线体。补洞
时直接用compound抹上会腐蚀绝缘层吗?compound肯定碰上最外层的纸了,纸下面就是
绝缘胶包着的铜线。 |
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a*o 发帖数: 25262 | 31 木头阳台, 有上漆, 日久风化, 边上有少量腐蚀。想先涂 compound 再上漆。去 HD 问
,可是没有室外 Compound。。。那里有卖? |
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c********l 发帖数: 8138 | 33 不是
http://www.homedepot.com/h_d1/N-5yc1vZ1xh7/R-
100398387/h_d2/ProductDisplay?langId=-1&storeId=10051&catalogId=10053
这个compound摸在手上有一点粘性。不像一般的spackle,spackle给人觉得都是粉末
上漆之前需要等24小时,令之完全干
COMPOUND/dp/B002OTDYOO |
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z*********n 发帖数: 94654 | 34 软硬度不一样的,如果只是补墙,最好就用那种light weight的dry wall putty
或者快干的compound。否则用普通join compound干了以后特别硬,想打磨是非常费胳
膊的一件事情 |
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f*****k 发帖数: 276 | 35 bathroom的drywall要补几个洞,和装新的drywall(bathroom专用的),请问应该用什
么特殊的防潮的joint compound吗?那个牌子? 还是一般的最一般的joint compound
? |
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x*********9 发帖数: 71 | 36 不大不小的几道划痕,以为补起来很容易,结果用putty knife抹了joint compound往
上涂,才发现手上怎么也控制不好,越涂越乱,结果一看,歪七扭八的糊了几个奇形怪
状的joint compound 图案,而且还厚厚薄薄。
怎么补救?买了砂纸,干了后,是不是使劲打磨就能恢复平整了? |
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M******9 发帖数: 223 | 37 大家有用compound bow and crossbow的么?crossbow能猎鹿么?crossbow似乎比
compound bow 好掌握,比rifle狩猎时间长,声音小,并且省弹药,大家怎么看? |
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c*********r 发帖数: 2097 | 38 借这个帖子问一下 compound bow 和 composite bow 有啥区别? 以前玩 diablo 2 的
时候经常看到 composite bow, 却没有 compound bow 谢谢。 |
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b*****e 发帖数: 5133 | 39 compound bow不是也有个ghost ring,和枪比哪个在先就不知道了,不过看compound
bow的结构觉得应该在后。 |
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b**s 发帖数: 4571 | 40 我在俱乐部射3D。我们都用compound bow, 有个人用弩. 我们的箭基本一个人单手都能
拔出来。弩射出的箭,经常是箭头会穿透靶子的另一侧。要两个人一个拉一个在另一边
推,还要用腿顶住3D靶子来帮着固定。小的3D靶子,好像完全穿透过。
从好玩上来说,还是recurve好玩。现代的compound弓和弩都可以先进到让一个新人1,
2个小时就能成为一个射手。而recurve才玩的有难度有味道。 |
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l********r 发帖数: 175 | 41 how to input the chemical compound names in latex correctly?
for example, SiO2, how to do it?
I used following: SiO$_2$, because if I used the $ sign earlier, then the
whole word will become italic. I just want to make chemical compound name
consistent with that from word, which does not have such kind of problems.
Anyone could help? thanks a lot. |
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x******3 发帖数: 92 | 42 现在需要从植物叶片中提取polar compound用作LC-MS/MS。查了文献,发现有很多种提
取方法,比如用热水,用一定比例的水-氯仿-甲醇等,提取的温度也不一样。我从来没
有用过植物的叶片,也不知道哪个方法能最有效的提取到想要的compound,请问有什么
建议吗?谢谢了先~ |
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w*******p 发帖数: 253 | 43 Compound Semiconductor Process Technician
Job Description
• Perform multiple processing and verification steps routinely in a
small III-V compound semiconductor fab.
• Processing steps include: photolithography, metallization, wet
and dry etching.
• Follow processing recipes and procedures.
• Do all steps of processing on a wafer from start to finish.
Requires three years of hands-on experience with lithography, etching,
deposition, and diagnostic testing of c |
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N***n 发帖数: 660 | 44 http://www.reuters.com/finance/stocks/keyDevelopments?symbol=PFE.N×tamp=20090224133200&rpc=66
Pfizer Discontinues Development Of Two Phase 3 Compounds
Tuesday, 24 Feb 2009 08:32am EST
Pfizer announced that, following a review of the development and commercial
portfolios in the Primary Care Business Unit, it is terminating Phase 3
development programs for the investigational compounds esreboxetine for
fibromyalgia and PD 332,334 for generalized anxiety disorder (GAD). The
decision to termina |
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b**o 发帖数: 5769 | 45 我去年参加了national student pharmacist compounding competetion,我们队还拿了
第一名呢。
推荐你参加这个比赛。拿不拿奖无所谓,会有很多业界大人物做presentation,受益多
多哦!
compounding的缺点就是job market不大,就业机会不是很多,不过如果你从现在开始
关注,总是会有机会的。
可以加入IACP,学生免费的。
http://www.iacprx.org/ |
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w*******y 发帖数: 60932 | 46 Back again Mwave has MASSCOOL STARS-700 silver thermal grease compound 0.5
gram:
http://www.mwave.com/mwave/SKUSearch.asp?scriteria=BA31168&page STARS-700 silver thermal grease compound 0.5 g
for $0.99 + FS
Description:
MASSCOOL STARS-700 Silver Thermal Grease
Thermal grease can be used on the rear side of the heatsink which has no
thermal pad. It will improve the heat dispatch of your processor.
Features:
Silver grease, Thermal grease
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w*******y 发帖数: 60932 | 47 Craftsman 10'' Compound Miter Saw (21236):
http://www.mygofer.com/shc/s/p_10175_27151_00921236000P
through mygofer.com
Shows $69.99 on the item page
Select shipping as delivery method
Add it to your cart
sign in or register if you are not already registered.
If you had to register add a shipping address in the next cart window
A discount of 13.95 will show up in your cart
Add code FIXITUP for another 10% off makig the total discount $20.95
Final Price - $49.04
Currently $112.49 at Sears:
http:... 阅读全帖 |
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w*******y 发帖数: 60932 | 48 Arctic Cooling MX-2 Thermal Compound - 4gram $2.99 f/s
Link:
http://www.mwave.com/mwave/SKUSearch.asp?px=DS&scriteria=AA7721
Description:
MX-2 is a high thermal conductivity and low thermal resistance compound for
components that require optimum thermal dissipation. It is ideally suited
for use in CPU, GPU cooling and other applications between power
semiconductor components and heat sinks where thermal conductivity is a
major factor.
Features:
High Thermal Conductivity
Low Thermal Resistance
No... 阅读全帖 |
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L*****d 发帖数: 5093 | 50 President and Mrs. Obama built/has a ten foot Wall around their D.C. mansion
/compound. I agree, totally necessary for their safety and security. The U.S
. needs the same thing, slightly larger version!
-Donald J. Trump |
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