w****g
发帖数: 256 | 1 1. 进行阿氏的时候喝咖啡到底影响有多大？
咖啡因与胰岛素
咖啡因能兴奋中枢神经，因而使肾上腺素等激素释放增多。这些激素增多，对血糖会有
什么影响呢？2002年2月发表的一篇报告中对此作了研究。研究内容是咖啡因对胰岛素
敏感性的影响。因为近年发现，腹部肥胖、糖尿病、高血压、高血脂等病人都有一个共
同的基础，在医学上称作“胰岛素抵抗”。意思是一定量的胰岛素不能发挥它应有的作
用，主要是降低血糖，亦即胰岛素敏感性降低。他们对12名健康志愿者，一方面从手臂
静脉注入咖啡因，另一方面测定胰岛素敏感性及各种激素。咖啡因的剂量是每千克体重
3毫克，一般女性为160毫克，男性约230毫克，相当于2大杯咖啡。
注射咖啡因后可见血压稍上升，前臂血流增加，心跳并不加快，但血中肾上腺素、去甲
肾上腺素及游离脂肪酸明显增加。此时用标准的方法测定胰岛素敏感性，可见用了咖啡
因以后，胰岛素敏感性较对照组降低15％。胰岛素敏感性下降，表示体内不易使血糖进
入细胞内供代谢应用，因而可能升高血糖。
从此研究结果来看，可以认为咖啡因对血糖控制不利。
2. 可以喝无糖可乐吗？ 貌似柠檬酸是三羧酸循環中间产物，对阿氏有影响。有同学能
详细讲讲吗？
•Citric acid, a common ingredient in diet soda and other diet
products, can stall weight loss for 40-50% of lowcarbers. If you are
sensitive to this substance it can slow down your weight loss by kicking you
out of ketosis.
柠檬酸 是 | G***a
发帖数: 27294 | 2 如果阿氏，咖啡因和柠檬酸最好都要戒除。原书要求最多decaf
【在 w****g 的大作中提到】
: 1. 进行阿氏的时候喝咖啡到底影响有多大？
: 咖啡因与胰岛素
: 咖啡因能兴奋中枢神经，因而使肾上腺素等激素释放增多。这些激素增多，对血糖会有
: 什么影响呢？2002年2月发表的一篇报告中对此作了研究。研究内容是咖啡因对胰岛素
: 敏感性的影响。因为近年发现，腹部肥胖、糖尿病、高血压、高血脂等病人都有一个共
: 同的基础，在医学上称作“胰岛素抵抗”。意思是一定量的胰岛素不能发挥它应有的作
: 用，主要是降低血糖，亦即胰岛素敏感性降低。他们对12名健康志愿者，一方面从手臂
: 静脉注入咖啡因，另一方面测定胰岛素敏感性及各种激素。咖啡因的剂量是每千克体重
: 3毫克，一般女性为160毫克，男性约230毫克，相当于2大杯咖啡。
: 注射咖啡因后可见血压稍上升，前臂血流增加，心跳并不加快，但血中肾上腺素、去甲
| w****g
发帖数: 256 | 3 我咖啡瘾很大，咖啡因+阿氏的坏处如果只是stall ketosis,那我倒不太 care。但是要
是因为咖啡因造成血糖浓度忽高忽低，有健康上的危险，我就要想想是quit atkins还
是quit caffine了。
【在 G***a 的大作中提到】
: 如果阿氏，咖啡因和柠檬酸最好都要戒除。原书要求最多decaf
| G***a
发帖数: 27294 | 4 阿氏的意义就是ketosis。。。。。不ketosis白受罪，
【在 w****g 的大作中提到】
: 我咖啡瘾很大，咖啡因+阿氏的坏处如果只是stall ketosis,那我倒不太 care。但是要
: 是因为咖啡因造成血糖浓度忽高忽低，有健康上的危险，我就要想想是quit atkins还
: 是quit caffine了。
| w****g
发帖数: 256 | 5 so far 我coffee, diet coke, crystal light energy一样没戒， ketostix在最紫和
第二紫之间，所以我不太担心ketosis. 我有点担心忽然晕倒之类的实际上的健康问题
，因为induction貌似一直在低血糖状态。
【在 G***a 的大作中提到】
: 阿氏的意义就是ketosis。。。。。不ketosis白受罪，
| G***a
发帖数: 27294 | 6 咖啡里面加heavy cream，应该可以避免
Heavy cream是纯乳脂，在一般超市里有卖，没有碳水。
和
【在 w****g 的大作中提到】
: so far 我coffee, diet coke, crystal light energy一样没戒， ketostix在最紫和
: 第二紫之间，所以我不太担心ketosis. 我有点担心忽然晕倒之类的实际上的健康问题
: ，因为induction貌似一直在低血糖状态。
| w****g
发帖数: 256 | 7 可以避免什么？
【在 G***a 的大作中提到】
: 咖啡里面加heavy cream，应该可以避免
: Heavy cream是纯乳脂，在一般超市里有卖，没有碳水。
:
: 和
| A***a
发帖数: 3603 | 8 我看过一篇文章，鼓励糖尿病人每天1杯咖啡，所以对你的第一点不能同意。
至于无糖可乐，现在有些study显示可能会让body储存更多的fat.但是这没有定论,你也
就听听。
以上我讲的和Atkins 无关，只是对咖啡因，代糖的一些看法。
★ Sent from iPhone App: iReader Mitbbs Lite 7.39 | G***a
发帖数: 27294 | 9 避免你血糖低晕过去。乳脂能压住咖啡因的降血糖作用
【在 w****g 的大作中提到】
: 可以避免什么？
| w****g
发帖数: 256 | 10 谢谢
【在 G***a 的大作中提到】
: 避免你血糖低晕过去。乳脂能压住咖啡因的降血糖作用
| | | k**********h
发帖数: 197 | 11 咖啡因和胰岛有关系？
【在 w****g 的大作中提到】
: 1. 进行阿氏的时候喝咖啡到底影响有多大？
: 咖啡因与胰岛素
: 咖啡因能兴奋中枢神经，因而使肾上腺素等激素释放增多。这些激素增多，对血糖会有
: 什么影响呢？2002年2月发表的一篇报告中对此作了研究。研究内容是咖啡因对胰岛素
: 敏感性的影响。因为近年发现，腹部肥胖、糖尿病、高血压、高血脂等病人都有一个共
: 同的基础，在医学上称作“胰岛素抵抗”。意思是一定量的胰岛素不能发挥它应有的作
: 用，主要是降低血糖，亦即胰岛素敏感性降低。他们对12名健康志愿者，一方面从手臂
: 静脉注入咖啡因，另一方面测定胰岛素敏感性及各种激素。咖啡因的剂量是每千克体重
: 3毫克，一般女性为160毫克，男性约230毫克，相当于2大杯咖啡。
: 注射咖啡因后可见血压稍上升，前臂血流增加，心跳并不加快，但血中肾上腺素、去甲
| w****g
发帖数: 256 | 12 2012年的小册子，Atkins carb counter and acceptable food list,在induction
phrase, beverages允许的包括，
...club soda; heavy or light cream or half and half (1-1.5 ounces a day),
caffeinated or decaffeinated coffee and tea; diet soda sweetened with
noncaloric sweeteners; lemon juice or lime juice (2-3 tablespoons a day),
plan or flavored seltzer (must say "no calories")....
【在 G***a 的大作中提到】
: 如果阿氏，咖啡因和柠檬酸最好都要戒除。原书要求最多decaf
| r**z
发帖数: 1793 | 13 11年的文章，没做出什么
Effects of caffeinated and decaffeinated coffee on biological risk factors
for type 2 diabetes: a randomized controlled trial.
Wedick NM, Brennan AM, Sun Q, Hu FB, Mantzoros CS, van Dam RM.
SourceDepartment of Nutrition, Harvard School of Public Health, Boston, MA,
USA. n*****[email protected]
Abstract
BACKGROUND: Coffee consumption has been associated with a lower risk of type
2 diabetes in prospective cohort studies, but the underlying mechanisms
remain unclear. The aim of this study was to evaluate the effects of regular
and decaffeinated coffee on biological risk factors for type 2 diabetes.
METHODS: Randomized parallel-arm intervention conducted in 45 healthy
overweight volunteers who were nonsmokers and regular coffee consumers.
Participants were assigned to consumption of 5 cups (177 mL each) per day of
instant caffeinated coffee, decaffeinated coffee, or no coffee (i.e., water
) for 8 weeks.
RESULTS: Average age was 40 years and body mass index was 29.5 kg/m2.
Compared with consuming no coffee, consumption of caffeinated coffee
increased adiponectin (difference in change from baseline 1.4 μg/mL; 95% CI
concentrations and consumption of decaffeinated coffee decreased fetuin-A
concentrations (difference: -20%; 95% CI: -35, -1). For measures of glucose
tolerance, insulin sensitivity, and insulin secretion, no significant
differences were found between treatment groups.
CONCLUSIONS: Although no changes in glycemia and/or insulin sensitivity were
observed after 8 weeks of coffee consumption, improvements in adipocyte and
liver function as indicated by changes in adiponectin and fetuin-A
concentrations may contribute to beneficial metabolic effects of long-term
coffee consumption. | G***a
发帖数: 27294 | 14 不要拿这种小册子当圣经。都是后面人胡写的。原本的书里明确写了不能有咖啡因。
能让你就着heavy cream喝，真的费了很多脑子了。
别在来来回回了。我求你们了。。一个个都非要阿氏，一个个又都不看书
★ 发自iPhone App: ChineseWeb - 中文网站浏览器
【在 w****g 的大作中提到】
: 2012年的小册子，Atkins carb counter and acceptable food list,在induction
: phrase, beverages允许的包括，
: ...club soda; heavy or light cream or half and half (1-1.5 ounces a day),
: caffeinated or decaffeinated coffee and tea; diet soda sweetened with
: noncaloric sweeteners; lemon juice or lime juice (2-3 tablespoons a day),
: plan or flavored seltzer (must say "no calories")....
| r**z
发帖数: 1793 | 15 这个做了同时口服脂质和咖啡因对糖耐量的影响，作者认为能降低糖耐量
J Nutr. 2011 Apr 1;141(4):574-81. Epub 2011 Feb 23.
An oral lipid challenge and acute intake of caffeinated coffee additively
decrease glucose tolerance in healthy men.
Beaudoin MS, Robinson LE, Graham TE.
SourceDepartment of Human Health and Nutritional Sciences, University of
Guelph, Guelph, Ontario N1G 2W1, Canada.
Abstract
Lipid-induced insulin resistance has been investigated primarily with i.v.
infusions, and caffeine-induced insulin resistance, with alkaloid caffeine.
The effects of orally consumed lipids and coffee have not been established
and to our knowledge have never been simultaneously investigated. The goals
of this study were to determine whether an oral lipid challenge and
caffeinated coffee would disrupt glucose homeostasis and to characterize
their respective incretin responses. It was hypothesized that oral ingestion
of saturated lipids would impair glucose tolerance and that caffeinated
coffee would further hinder glucose management. Ten young, healthy males
participated in 5 trials in a randomized, cross-over design. At time 0 h,
they underwent an oral fat tolerance test (OFTT: 1 g lipid/kg body weight)
or consumed water, followed 5 h later by caffeinated (5 mg/kg) coffee,
decaffeinated coffee, or water. At 6 h, volunteers underwent an oral glucose
tolerance test (OGTT). Consumption of the OFTT increased glucose
concentrations (P < 0.05) after a subsequent OGTT. At 7 h, caffeinated
coffee produced the highest glucose concentrations (P < 0.05). Glucagon-like
peptide-1 active (GLP-1a) and glucose-dependent insulinotropic polypeptide
(GIP) were both increased for up to 6 h in all OFTT trials (P < 0.05).
Compared to all other treatments, caffeinated and decaffeinated coffee
produced higher GLP-1a response at 6.25 h (P < 0.05), whereas only
caffeinated coffee increased GIP secretion (P < 0.05). These results show
that oral consumption of lipids and caffeinated coffee can independently and
additively decrease glucose tolerance. Incretin hormones could explain at
least in part this impaired glucose homeostasis. | r**z
发帖数: 1793 | 16 看到第三篇 又是不同结论
Diabetologia. 2011 Feb;54(2):320-8. Epub 2010 Nov 3.
Associations between the intake of caffeinated and decaffeinated coffee and
measures of insulin sensitivity and beta cell function.
Loopstra-Masters RC, Liese AD, Haffner SM, Wagenknecht LE, Hanley AJ.
SourceDepartment of Nutritional Sciences, Faculty of Medicine, University of
Toronto, FitzGerald Building, 150 College St, Toronto, ON, Canada.
Abstract
AIMS/HYPOTHESIS: Although protective relationships between coffee
consumption and type 2 diabetes mellitus have consistently been observed,
few studies have examined the relationships between coffee consumption and
underlying pathophysiological defects that characterise diabetes aetiology.
The aim of this study was to explore the associations between caffeinated
and decaffeinated coffee consumption and measures of insulin sensitivity and
secretion.
METHODS: The study population included 954 multi-ethnic non-diabetic adults
from the Insulin Resistance Atherosclerosis Study (IRAS). Multiple
regression analyses were performed to examine the cross-sectional
relationships between caffeinated and decaffeinated coffee intake and
insulin sensitivity and acute insulin response, measured by a frequently
sampled intravenous glucose tolerance test, 2 h postload glucose measured by
OGTT, fasting insulin, and proinsulin to C-peptide ratios.
RESULTS: Caffeinated coffee intake was positively associated with insulin
sensitivity (β = 0.054; SE = 0.026; p = 0.04) and inversely related to 2 h
postload glucose (β = -0.37; SE = 0.10; p = 0.0003) in fully adjusted
models. Caffeinated coffee intake was not associated with acute insulin
response or proinsulin ratios. Decaffeinated coffee intake was inversely
related to 2 h postload glucose (β = -0.47; SE = 0.18; p = 0.0096)
and positively related to acute insulin response (β = 0.191; SE = 0.077; p
= 0.0132). Decaffeinated coffee intake was inversely related to the ratios
of both intact and split proinsulin to C-peptide (β = -0.150; SE = 0.
061; p = 0.0148; β = -0.254; SE = 0.068; p = 0.0002, respectively).
CONCLUSIONS/INTERPRETATION: In this cross-sectional study, caffeinated
coffee was positively related to insulin sensitivity and decaffeinated
coffee was favourably related to measures of beta cell function. These
results provide pathophysiological insight as to how coffee could impact the
risk of type 2 diabetes mellitus.
总而言之，言而总之，2011年大家还在疯狂做这个东西，说明还没有定论 大家稍安勿
躁 | w****g
发帖数: 256 | 17 阿博士自己也挺搞的，第一版说sugar alcohol也得算carbs，第二版开始自己卖bars/
shakes loaded with sugar alcohol就说不用算了。
【在 G***a 的大作中提到】
: 不要拿这种小册子当圣经。都是后面人胡写的。原本的书里明确写了不能有咖啡因。
: 能让你就着heavy cream喝，真的费了很多脑子了。
: 别在来来回回了。我求你们了。。一个个都非要阿氏，一个个又都不看书
:
: ★ 发自iPhone App: ChineseWeb - 中文网站浏览器
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